aortic pseudoaneurysm

主动脉假性动脉瘤
  • 文章类型: Journal Article
    背景:钝性创伤性主动脉损伤(BTAI)是年轻患者因创伤导致死亡的第二大原因。主要表现可能是胸部或肩胛骨间疼痛,呼吸困难,and,在严重的情况下,低血压。考虑到这些患者的临床状况迅速恶化,及时诊断和开始治疗至关重要。在这些伤害中,主动脉受累最多的部分是峡部(左锁骨下动脉远端)和胸腔的降部。因此,主要的诊断策略包括经胸超声心动图,CT血管造影,和血管内诊断方法。病例介绍患者是一名19岁男性,有胸痛症状,呼吸困难,汽车周转后四肢极度疼痛。初步评估显示,除了双侧血胸,没有异常的心血管发现。用胸管处理。十二小时后,当病人接受骨科手术观察时,他开始胸痛和呼吸困难,TTE和CTA显示主动脉瓣三降动脉瘤。患者立即接受了支架植入的血管内手术治疗。还进行了延迟脱支手术,这导致了理想的结果和顺利的后续行动。
    结论:尽管开胸手术是治疗血流动力学不稳定患者主动脉瘤的主要且几乎是唯一的选择,在具有适当解剖结构的选定患者中,血管内手术显示出优异的结局。脱支手术,可以在初始程序之后同时或延迟进行,已证明对血栓栓塞性脑事件有保护作用。
    主动脉瘤患者应与多学科小组一起送往医疗中心进行紧急评估和治疗。最初的复苏和诊断具有挑战性,考虑到这些伤害的致命性质,治疗方法的选择是基于患者的临床状况和心血管影像学的解剖学评估。
    BACKGROUND: Blunt traumatic aortic injury (BTAI) is the second leading cause of death due to traumas in young patients. The primary presentation might be chest or interscapular pain, difficulty in breathing, and, in severe cases, hypotension. Considering the rapid deterioration of these patients\' clinical conditions, prompt diagnosis and treatment initiation are crucial. In these injuries, the most involved parts of the aorta are the isthmus (distal to the left subclavian artery) and the descending part in the thorax. Therefore, the main diagnostic strategies include transthoracic echocardiography, CT angiography, and endovascular diagnostic approaches. Case presentation The patient was a 19-year-old male presenting with the symptoms of chest pain, dyspnea, and extremities excruciating pain after a car turnover. The initial evaluation showed no abnormal cardiovascular finding except bilateral hemothorax, addressed with chest tubes. Twelve hours later, when the patient was under observation for orthopedic surgeries, his chest pain and dyspnea started, and TTE and CTA showed a grade three descending aneurysm of the aorta. The patient was treated immediately with an endovascular procedure of stent implantation. A delayed debranching surgery was also performed, which resulted in desirable outcomes and uneventful follow-up.
    CONCLUSIONS: Although open thoracic surgery is the main and almost the only option for treating aneurysms of the aorta in hemodynamically unstable patients, the endovascular procedure has shown superior outcomes in selected patients with appropriate anatomy. Debranching surgery, which can be done simultaneously or with delay after the initial procedure, has proven protective against thromboembolic cerebral events.
    UNASSIGNED: Patients with an aneurysm of the aorta should be transported to a medical center with a multidisciplinary team for an urgent evaluation and treatment. The initial resuscitation and diagnosis are challenging, considering the fatal nature of these injuries, and the selection of the treatment is based on the patient\'s clinical condition and evaluated anatomy in cardiovascular imaging.
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  • 文章类型: Case Reports
    背景:真菌性心内膜炎是一种罕见但严重的疾病,与高死亡率相关。各种诱发因素促成了它的发生,比如潜在的心脏异常,心脏手术,人工心脏装置,和中央静脉导管.诊断真菌性心内膜炎,特别是曲霉,带来挑战,经常因阴性血培养而复杂化。
    方法:本报告详细介绍了一例24岁男性的升主动脉广泛累及曲霉菌性心内膜炎(AE)的病例,该男性有生物瓣主动脉瓣置换术(AVR)的病史。AVR后三个月,他出现了心包积液和主动脉破裂,导致重做生物瓣膜导管主动脉根部置换术(Bentall手术)。尽管有干预,管状移植物表现出广泛的曲霉参与,导致移植物破裂和显著的主动脉周围感染。进行了第二次重做手术,涉及主动脉同种异体移植根置换。不幸的是,病人在手术后两天死亡。
    结论:建议采用内科和外科联合治疗的方法治疗真菌性心内膜炎。尽管努力,与曲霉菌心内膜炎相关的死亡率仍然高得令人无法接受,联合治疗和单独抗真菌治疗之间没有显着差异。进一步的研究对于探索新的治疗策略和改善患有这种挑战性疾病的患者的预后至关重要。
    BACKGROUND: Fungal endocarditis is a rare but serious condition associated with high mortality rates. Various predisposing factors contribute to its occurrence, such as underlying cardiac abnormalities, cardiac surgeries, prosthetic cardiac devices, and central venous catheters. Diagnosing fungal endocarditis, particularly Aspergillus, poses challenges, often complicated by negative blood cultures.
    METHODS: This report details a case of extensive ascending aorta involvement in Aspergillus endocarditis (AE) in a 24-year-old man with a history of bioprosthesis aortic valve replacement (AVR). Three months post-AVR, he presented with pericardial effusion and aortic rupture, leading to a redo biological valved conduit aortic root replacement (Bentall surgery). Despite the intervention, the tubular graft exhibited extensive Aspergillus involvement, resulting in graft disruption and significant peri-aortic infection. A second redo procedure involving aortic homograft root replacement was performed. Unfortunately, the patient succumbed two days after the surgery.
    CONCLUSIONS: A combined approach of medical and surgical therapies is recommended to manage fungal endocarditis. Despite efforts, the mortality rate associated with Aspergillus endocarditis remains unacceptably high, with no significant difference observed between combination therapy and antifungal treatment alone. Further research is essential to explore novel therapeutic strategies and improve outcomes for patients with this challenging condition.
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  • 文章类型: Case Reports
    “咯血”是指从呼吸道咳出的血液。然而,“危及生命的咯血”包括导致气道阻塞等特征的任何体积,缺氧,或血流动力学不稳定。我们介绍了一例65岁的男性,有良性前列腺增生和不受控制的高血压病史,发生危及生命的咯血。放射学检查显示,在童年时期50多年前,先前的胸主动脉缩窄修复部位存在假性动脉瘤。他需要血管外科手术,在此期间,有证据表明主动脉-支气管瘘可能是出血的原因。在修复和最佳血压控制之后,患者没有进一步的咯血发作,已出院。他的病例不仅增加了越来越多的医学文献报道咯血是缩窄修复的并发症,而且还强调了主动脉支气管瘘是这些患者出血的可能且潜在的灾难性机制。
    \"Hemoptysis\" refers to the expectoration of blood from the respiratory tract. However, \"life-threatening hemoptysis\" includes any volume that leads to features such as airway obstruction, hypoxia, or hemodynamic instability. We present a case of life-threatening hemoptysis in a 65-year-old male with a history of benign prostatic hyperplasia and uncontrolled hypertension. Radiological investigations revealed a pseudo-aneurysm at the site of a prior thoracic aortic coarctation repair more than 50 years prior in childhood. He required vascular surgical intervention, during which there was evidence of an aorta-bronchial fistula as the likely cause of bleeding. Following the repair and optimal blood pressure control, the patient had no further episodes of hemoptysis and was discharged from the hospital. His case not only adds to the growing body of medical literature reporting hemoptysis as a complication of coarctation repair but also highlights the aorto-bronchial fistula as a possible and potentially catastrophic mechanism for bleeding in these patients.
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  • 文章类型: Journal Article
    背景:胸主动脉假性动脉瘤是心脏手术后可能发生的危险并发症。它们往往导致高死亡率。这些动脉瘤是由主动脉壁的所有层的损伤引起的。本研究旨在查明实验标本的面积(天然血管,吻合,或假体移植物)变形最大,以确定吻合部位是否可能发生假性动脉瘤。
    方法:我们通过执行从0到20的八个周期来进行充气-扩展测试。压力采样频率为100Hz,每个周期持续大约34秒,导致0.03Hz的加载频率。在实验过程中,每台摄像机拍摄3000帧。根据收集的数据,我们评估并比较了第1周期和第8周期的加载阶段。
    结论:在加载过程中,天然血管在圆周方向上经历了大约7%的主要变形。假体移植物,具有纵向结构,轴向变形约8%。假体移植物,另一方面,在圆周方向上只经历了高达1.5%的变形,这比天然血管的变形小约5倍。吻合区域非常坚硬,变形最小。此外,第一个C1和第八个C8循环之间的机械响应几乎没有差异。
    结论:根据现有证据,可以推断,主动脉假性动脉瘤更有可能形成在原生主动脉的缝合线后面,与吻合口和假体移植物的坚硬部分相比,弹性更大。天然血管的大量搏动可能会导致吻合边缘处的主动脉受损。这将导致主动脉壁的破坏和吻合区域附近天然血管中的假动脉瘤形成。
    BACKGROUND: False aneurysms in the thoracic aorta are dangerous complications that can occur after cardiac surgery. They often result in high mortality rates. These aneurysms are caused by damage to all layers of the aortic wall. This study aimed to pinpoint the area of the experimental specimen (native vessel, anastomosis, or prosthetic graft) with the greatest deformation, to determine whether a false aneurysm is likely to develop in the anastomotic portion.
    METHODS: We conducted the inflation-extension test by performing eight cycles ranging from 0 to 20. The pressure sampling frequency was 100 Hz, and each cycle lasted approximately 34 seconds, resulting in a loading frequency of 0.03 Hz. During the experiment, each camera captured 3,000 frames. Based on the data collected, we evaluated and compared the loading stages of cycle 1 and cycle 8.
    CONCLUSIONS: During loading, the native vessel experienced a dominant deformation of approximately 7% in the circumferential direction. The prosthetic graft, which had a longitudinal construction, deformed by approximately 8% in the axial direction. The prosthetic graft, on the other hand, only experienced a deformation of up to 1.5% in the circumferential direction, which was about 5 times smaller than the deformation of the native vessel. The anastomosis area was very stiff and showed minimal deformation. Additionally, there was little difference in the mechanical response between the first C1 and the eighth C8 cycle.
    CONCLUSIONS: Based on the available evidence, it can be inferred that aortic false aneurysms are more likely to form just behind the suture lines in the native aorta, which is more elastic compared to stiff sections of anastomosis and prosthetic graft. Numerous pulsations of the native vessel will likely cause the impairment of the aorta at the margin of the anastomosis. This will lead to disruption of the aortic wall and false aneurysm formation in the native vessel near the area of anastomosis.
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  • 文章类型: Case Reports
    主动脉假性动脉瘤是心脏手术后出现的并发症,胸部外伤,感染,或炎性疾病。主动脉假性动脉瘤的主要治疗方法是手术治疗。鉴于与开胸手术相关的显著发病率和死亡率,高危患者不考虑进行心脏手术.正在探索使用各种设备的新型经皮修复,尤其是那些有心脏手术风险的人。
    本案例描述了使用Amplatzer房间隔缺损(ASD)封堵器治疗一名69岁男性的主动脉假性动脉瘤,该男性此前曾接受过冠状动脉旁路移植术和心包引流治疗化脓性心包炎。植入成功后,随访2年后无并发症发生.
    用AmplatzerASD封堵装置经皮封堵霉菌性假性动脉瘤是一种安全有效的治疗选择,尤其是手术风险过高的患者。
    UNASSIGNED: Aortic pseudoaneurysms are complications that arise following cardiac surgery, thoracic trauma, infections, or inflammatory conditions. The mainstay treatment for aortic pseudoaneurysm is surgical management. Given significant morbidity and mortality related to thoracotomy, high-risk patients are not considered for cardiac surgery. Novel percutaneous repair using a variety of devices are being explored, especially in those with prohibitive risk for cardiac surgery.
    UNASSIGNED: This case describes the use of an Amplatzer atrial septal defect (ASD) occluder device to manage an aortic pseudoaneurysm in a 69-year-old male who had previously undergone coronary artery bypass graft surgery and pericardial drainage for purulent pericarditis. Following successful implant, there were no complications seen after 2 years of follow-up.
    UNASSIGNED: Percutaneous closure of a mycotic pseudoaneurysm with an Amplatzer ASD occluder device can be a safe and efficacious treatment option, especially in patients with prohibitive surgical risk.
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  • 文章类型: Journal Article
    背景:胸主动脉假性动脉瘤(TAFA)是心脏手术后尚未发现的并发症,与显著的发病率和死亡率相关。因此,这项研究的目的是检查临床概况,外科技术,和手术结果,在单一机构接受TAFA治疗的患者。
    方法:从1996年到2022年,112例患者接受了主动脉假性动脉瘤治疗(平均年龄55±14岁,78例患者为男性)。在大多数患者(90%)中,TAFA是在以前的心血管手术后发展的,TAFA发生前最常见的诊断和外科手术是主动脉夹层(52%)和Bentall手术(47%).在其他人中,主要原因是外伤.
    结果:61%的患者接受了再干预(手术再手术,腔内移植物植入,间隔封堵器植入,线圈栓塞,或程序的组合)。总的来说,52例患者进行了心脏再手术。切除了TAFA,修复了55%的主动脉或替换了45%的主动脉。手术死亡率为5.7%。在术后随访中,围绕主动脉假体的低回声病变占94%,因此,它被确定为阴性预后因素。平均随访13.2±19.4年。
    结论:虽然没有防止TAFA发展的具体方法,应保持正常血压和定期随访。对于低回声病变环绕和主动脉假体的患者,应进行更频繁的随访。术后长期随访早期发现,多学科团队个性化的方法对于良好的治疗结果是必要的.
    BACKGROUND: Thoracic aorta false aneurysms (TAFA) are unexplored complications after cardiac surgery associated with significant morbidity and mortality. Therefore, the purpose of this study was to examine the clinical profiles, surgical techniques, and operative outcomes, of patients treated for TAFA at a single institution.
    METHODS: From 1996 to 2022, 112 patients were treated for aortic pseudoaneurysm (mean age 55 ± 14 years, 78 patients were male). In the majority of the patients (90%) TAFA developed after previous cardiovascular surgery, the most common diagnosis and surgical procedure preceding the TAFA development was an aortic dissection (52%) and Bentall procedure (47%). In the rest of the cohort, the leading cause was trauma.
    RESULTS: Sixty-one percent of patients were indicated for reintervention (surgical reoperation, endoluminal graft implantation, septal occluder implantation, coil embolization, or a combination of procedures). Overall, 52 patients had undergone cardiac reoperation. TAFA was resected and the aorta was repaired in 55% or replaced in 45%. Operative mortality was 5.7%. In postoperative follow-up, a hypoechogenic lesion encircling aortic prosthesis was present in 94%, therefore it was determined as a negative prognostic factor. The mean follow-up was 13.2 ± 19.4 years.
    CONCLUSIONS: Although there is no specific approach how to prevent TAFA development, maintaining normal blood pressure and regular follow-up should be applied. More frequent follow-ups should be performed in patients with a hypoechogenic lesion encircling and aortic prosthesis. Early detection during long-term postoperative follow-up, an individually tailored approach of a multidisciplinary team is necessary for favorable treatment outcomes.
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  • 文章类型: Case Reports
    背景:对于患有严重左主干冠状动脉疾病的患者,手术血运重建后有许多已知的并发症。病例描述本病例报告重点介绍了术前检查,手术方法,以及在行CABG后2年出现主动脉假性动脉瘤和夹层的患者的术后管理。结论在先前的冠状动脉旁路移植术(CABG)后,主动脉假性动脉瘤合并升主动脉夹层的发展是罕见的并发症,在文献中几乎没有报道。
    Background  There are many known complications that occur after surgical revascularization for patients with significant left main coronary artery disease. Case Description  This case report highlights the preoperative workup, surgical approach, and postoperative management of a patient who presents with an aortic pseudoaneurysm and dissection 2 years after the index CABG. Conclusion  The development of an aortic pseudoaneurysm in combination with an ascending aortic dissection after prior coronary artery bypass grafting (CABG) is a rare compilation of complications that has scarcely been reported in the literature.
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  • 文章类型: Case Reports
    穿透性主动脉损伤很少见。其发病率未知,因为大多数患者甚至在接受适当治疗之前就死于出血。主动脉伤口通常需要常规的开胸/开腹手术修复,并且与高死亡率相关。最近随着血管内技术的出现,在可行的情况下,大多数作者更喜欢血管内治疗,因为预后较好(仍然较差).创伤主动脉损伤的即刻腔内修复的短期和中期结果是有希望的,特别是与开放手术治疗相比,表明血管内治疗对于多发创伤和胸主动脉外伤性破裂的患者是优选的。在这里,我们介绍了一名30岁的男性患者的诊断和治疗,包括主动脉前裂伤伴II级主动脉病变,通过血管内支架移植物成功治疗。
    Penetrating aortic injuries are infrequent. Its incidence is unknown because most patients die of hemorrhage even before they receive adequate treatment. Aortic wounds generally require conventional thoracotomy/laparotomy repair and are related to high mortality rates. Recently with the advent of endovascular techniques, most authors prefer endovascular management when feasible due to better (still poor) outcomes. The short- and mid-term results of immediate endovascular repair of traumatic aortic injuries are promising, especially when compared with open surgical treatment, indicating that endovascular therapy is preferable in patients with multi-trauma and traumatic ruptures of the thoracic aorta. Here we present the diagnosis and treatment of a 30 years-old male patient with multiple traumatic stab wounds, including anterior aortic laceration with a grade II aortic lesion successfully managed with an endovascular stent graft.
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  • 文章类型: Journal Article
    目的:胸主动脉假性动脉瘤(TAP)是一种罕见但危及生命的疾病。本研究旨在调查TEVAR后TAP患者的早期和中期临床结局,并确定潜在的死亡率预测因素。
    方法:我们回顾性分析了2010年7月至2020年7月我院收治的37例TAP患者。我们探索了他们的基线,围手术期和随访数据。Fisher精确检验和Kaplan-Meier方法用于比较组间差异。
    结果:有29名男性和12名女性,平均年龄为59.5±13.0岁(范围30-82岁)。平均随访时间为30.7±28.3个月(范围1-89)。对于早期结果(≤30天),3例(8.1%)TAP第3区患者死亡,4区0例(p=0.028);术后1例(2.7%)患者发生下肢急性动脉栓塞和II型内漏。对于中期结果,存活3个月,1年和5年为88.8%,75.9%和68.3%,显示2/3区与4区组之间存在显着差异(56.3%vs.72.9%,p=0.013)和紧急TEVAR组与选择性TEVAR组(0.0%对80.1%,p=0.049)。既往支架移植术或食管异物伴主动脉食管瘘(AEF),全身性血管炎,作为病因,结果令人鼓舞,但中期预后较差。
    结论:与第4区病变和选择性TEVAR相比,第2/3区的TAP病变和紧急TEVAR预测更差的中期结局。结果也主要受到TAP病因的限制。
    OBJECTIVE: Thoracic aortic pseudoaneurysm (TAP) is an uncommon but life-threatening condition. The present study aimed to investigate the early and midterm clinical outcome of TAP patients following TEVAR and identify potential mortality predictors.
    METHODS: We retrospectively reviewed a series of 37 eligible patients with TAP admitted to our hospital from July 2010 to July 2020. We explored their baseline, perioperative and follow-up data. Fisher exact test and Kaplan-Meier method were applied for comparing difference between groups.
    RESULTS: There were 29 men and 12 women, with the mean age as 59.5 ± 13.0 years (range 30-82). The mean follow-up period was 30.7 ± 28.3 months (range 1-89). For early outcome (≤ 30 days), mortality happened in 3 (8.1%) zone 3 TAP patients versus 0 in zone 4 (p = 0.028); postoperative acute arterial embolism of lower extremity and type II endoleak respectively occurred in 1(2.7%) case. For midterm outcome, survival at 3 months, 1 year and 5 years was 88.8%, 75.9% and 68.3%, which showed significant difference between zone 2/3 versus zone 4 group (56.3% vs. 72.9%, p = 0.013) and emergent versus elective TEVAR group (0.0% versus 80.1%, p = 0.049). Previous stent grafting or esophageal foreign body with Aortoesophageal fistula (AEF), and systemic vasculitis, as etiologies, resulted in encouraging immediate outcome but worse midterm prognosis.
    CONCLUSIONS: TAP lesions at zone 2/3 and emergent TEVAR predict worse midterm outcomes compared to zone 4 lesions and elective TEVAR. The outcomes are also mainly restricted by the etiology of the TAP.
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  • 文章类型: Journal Article
    一名64岁的男性患者出现溶血性贫血的症状,被转诊到我们医院。在获得患者病史后,发现溶血发生在他接受升主动脉置换术治疗急性A型主动脉夹层14年后。增强计算机断层扫描显示近端吻合处的主动脉假性动脉瘤,这被认为是溶血的原因。此外,在经胸超声心动图中还发现了主动脉瓣反流和Valsalva窦扩张。因此,进行了Bentall手术。在手术过程中,观察到主动脉假性动脉瘤形成和血管移植物狭窄。术后进展顺利,手术后不久溶血减少。
    A 64-year-old male patient who presented with symptoms indicative of hemolytic anemia was referred to our hospital. After obtaining the patient\'s history, it was found that hemolysis occurred 14 years after he underwent ascending aortic replacement for acute type A aortic dissection. Enhanced computed tomography revealed an aortic pseudoaneurysm at the proximal anastomosis, which was thought to be the cause of hemolysis. Furthermore, aortic valve regurgitation and dilatation of the sinus of Valsalva were also found on a transthoracic echocardiogram. Therefore, the Bentall procedure was performed. During the surgery, aortic pseudoaneurysm formation and vascular graft stenosis were observed. The postoperative course was uneventful, and hemolysis diminished soon after the surgery.
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