anthropometric

人体测量学
  • 文章类型: Journal Article
    人为因素工程师需要准确的人体测量数据来设计安全的军事设备,舒适,使性能在极端的操作条件下和最恶劣的环境。国防部(MOD)承认,其当前的人体测量数据集越来越无法代表当今的武装部队人员,特别是妇女和少数民族。为了解决这个问题,国防部推出了一个新的,全面的人体测量学调查。虽然这项调查有可能有利于所有新的军事装备和服装的设计,这项研究的主要驱动力是为英国武装部队人员开发新的防弹衣。本文描述了支撑本次调查的要求,专注于防弹衣;计划的解决方案;以及测试鲁棒性的试点研究结果,测量技术和程序的可靠性和准确性。本文报告的工作由国防部的国防创新部门资助。从业者声明:英国国防部已经推出了一项新的,全面的人体测量学调查,承认其当前的人体测量学数据集越来越无法代表当今的武装部队人员。本文描述了支撑调查的要求,计划的解决方案和试点研究的结果。
    Human Factors Engineers need accurate anthropometric data to design military equipment that is safe, comfortable and enables performance under extreme operational conditions and in the most severe environments. The Ministry of Defence (MOD) acknowledges that its current anthropometry dataset is becoming increasingly unrepresentative of today\'s Armed Forces personnel, particularly women and minority ethnic groups. To address this issue, MOD has launched a new, comprehensive anthropometry survey. Whilst this survey has the potential to benefit the design of all new military equipment and clothing, the principal driver for the study is the development of new body armour for the UK\'s Armed Forces personnel. This paper describes the requirements underpinning this survey, with a focus on body armour; the planned solution; and the results of Pilot Studies that have tested the robustness, reliability and accuracy of the measurement technologies and procedures. The work reported in this paper has been funded by the MOD\'s Defence Innovation Unit.Practitioner statement: The UK Ministry of Defence has launched a new, comprehensive anthropometry survey, in acknowledgement of the fact that its current anthropometry dataset is becoming increasingly unrepresentative of today\'s Armed Forces personnel. This paper describes the requirements underpinning the survey, the planned solution and the result of Pilot Studies.
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  • 文章类型: Journal Article
    糖尿病,迅速增加的异质性疾病,与肥胖和代谢综合征(MetS)的流行密切相关。目前,我们不完全了解血液生物标志物,分子病因学,以及改变生活方式和干预措施在抗击糖尿病与肥胖和MetS流行方面的作用。
    为了测量糖尿病前期和糖尿病患者的不同人体测量和血液生物标志物,我们收集了医院OPD患者的数据和血液样本.这是一项横断面研究,包括识别不同参数之间可能的关系,以预测糖尿病的早期诊断标志物。
    我们发现体重指数(BMI)增加,空腹血糖,脖子,腰部,和臀围,矢状腹部直径,与糖尿病前期组相比,糖尿病患者的皮肤褶皱厚度。此外,糖尿病患者的血清尿酸和胰岛素抵抗(HOMA-IR)值显著升高.我们发现血尿酸与BMI呈显著正相关,空腹血糖,血清胰岛素,和HOMA-IR值。
    这里,我们发现糖尿病前期和糖尿病患者的空腹血糖水平升高,而胰岛素水平没有任何差异.糖尿病前期和糖尿病患者都表现出高血尿酸,与更高的糖尿病患病率和HOMA-IR呈正相关。因此尿酸可能是早期诊断的重要参数。这些发现可以作为未来研究的基础,这些研究旨在确定尿酸与胰岛素信号相关的机制细节,从而更好地理解与糖尿病相关的现象。
    在线版本包含补充材料,可在10.1007/s40200-023-01276-4获得。
    UNASSIGNED: Diabetes, a rapidly increasing heterogeneous disorder, is closely linked to the epidemic of obesity and metabolic syndrome (MetS). At present, we do not understand completely the blood biomarkers, molecular aetiology, and role of lifestyle modification and interventions to combat diabetes hand in hand with obesity and the MetS epidemic.
    UNASSIGNED: To measure different anthropometric and blood biomarkers in pre-diabetic and diabetic patients, we collected data and blood samples from patients in a hospital OPD. This was a cross-sectional study that included the identification of possible relationships between different parameters to predict early diagnostic markers of diabetes.
    UNASSIGNED: We found increased body mass index (BMI), fasting blood glucose, neck, waist, and hip circumference, sagittal abdominal diameter, and skin fold thickness in the diabetic as compared to the pre-diabetic group. Also, serum uric acid and insulin resistance (HOMA-IR) values were significantly increased in diabetic individuals. We found a significant positive correlation between serum uric acid and BMI, fasting blood glucose, serum insulin, and HOMA-IR values.
    UNASSIGNED: Here, we found that pre-diabetic and diabetic patients have increased fasting glucose levels while we did not find any difference in insulin levels. Both pre-diabetic and diabetic patients show high serum uric acid, positively associated with a higher prevalence of diabetes and HOMA-IR. Uric acid may hence be an important parameter for early diagnostics. These findings may be used as a basis for future studies that aim to identify the mechanistic details of the association of uric acid with insulin signaling and hence better understanding of the phenomenon associated with diabetes.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s40200-023-01276-4.
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  • 文章类型: Journal Article
    视频监控系统的增加凸显了对犯罪并在犯罪活动中被摄像机捕获的受试者进行法医人体测量分析的兴趣。人类身高估计有不同的方法。法医研究人员开发了一种方法学方法,可以通过3D激光扫描采集和视频监控系统采集的视频图像的组合模型来估计受试者的身高。拟议的研究强调了三个限制:没有对图像校正进行评估以限制失真效应,该方法仅由一个实验室进行了测试,身高评估可能取决于人体工程学。为了克服这些限制,在本文中,通过校正图像来重复分析,以将获得的新结果与以前的结果进行比较。此外,同样的方法是通过估计人体模型的高度,为了限制人体工程学效果,并向三个不同的法医实验室提出相同的研究结果。提出的研究证明了系统的可靠性和可重复性,因为三个实验室获得的结果非常相似。他们获得了相同的趋势,最大估计距离约为6厘米。此外,它表明,结果的准确性取决于图像校正,这对高度评估几乎没有影响(在校正帧上比正常帧更精确大约1厘米),并且它们不依赖于所捕获的受试者的人体工程学。
    The increase of video surveillance systems has highlighted the interest in forensic anthropometric analysis of subjects who commit crimes and are captured by cameras during their criminal activities. There are different methodologies for human height estimation. Forensic researchers developed a methodological approach that allows the height of a subject to be estimated through a combined model of 3D laser scanning acquisition and video images acquired by video surveillance systems. The proposed study had highlighted three limits: not assessments had been made for image correction to limit the distortion effect, the method had been tested by only one laboratory and probably height assessment was dependent on the ergonomics. To overcome these limitations, in this paper the analysis was repeated by correcting the images to compare the new results obtained with the previous ones. Furthermore, the same methodological approach was applied by estimating the height of a mannequin, to limit the ergonomic effects, and proposing the same study to three different forensic laboratories to compare the results. The presented study demonstrates the reliability and repeatability of the system, as the results obtained by the three laboratories are very similar. They have obtained the same trend and the maximum estimate distance is approximately 6 cm. Furthermore, it has showed that the accuracy of results is dependent on image correction, which has little impact (approximately 1 cm more accurate on the corrected frame than the normal frame) on the height evaluation and they are not dependent to the ergonomics of the subject captured.
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  • 文章类型: Journal Article
    这项研究旨在将LaAraucanía地区超重/肥胖和体重正常的智利成年人的身体成分(通过五室模型和DXA的三室模型通过人体测量学获得)与骨密度以及生化和营养参数进行比较和联系,智利。对来自PURE队列的116名成年人和志愿者进行了病例对照研究。收集社会人口统计数据,BMI评估,腰臀比(WHR),和身体成分使用DXA的五室模型(5CM)和三室模型(3CM),以及骨矿物质密度(BMD)。血液生化指标(空腹血糖和血脂),通过GPAQ测量的身体活动(PA),并测量了平均饮食习惯(R24h)。在超重/肥胖组中,5CM和3CM脂肪量与PA间接和中度相关(p<0.05),男性5CM组除外。在超重/肥胖组中,5CM和3CM的肌肉和无脂质量(FFM)与空腹血糖(BFG)和BMD直接和中度相关(p<0.05),除了女性,其中FFM与BMD无关,但与残余质量有关(p<0.01)。与性别和BMI无关,骨矿物质含量与骨密度呈正相关(p<0.0000)。在男性超重/肥胖组中,骨头,皮肤,残余质量与BFG相关(p<0.05)。总之,对于非运动成人人群的评估,建议在临床实践中更常规使用5CM。
    This study aimed to compare and relate the body composition (obtained through anthropometry with the pentacompartmental model and the tricompartmental model by DXA) with bone mineral density and biochemical and nutritional parameters in Chilean adults with overweight/obesity and normal weight from La Araucanía region, Chile. A case-control study was conducted with 116 adults and volunteers from the PURE cohort, collecting sociodemographic data, BMI assessment, waist-to-hip ratio (WHR), and body composition using the pentacompartmental model (5CM) and tricompartmental model (3CM) by DXA, as well as bone mineral density (BMD). Blood biochemical parameters (fasting glucose and lipid profile), physical activity (PA) measured by GPAQ, and average dietary habits (R24h) were measured. In the overweight/obesity group, the 5CM and 3CM adipose mass were indirectly and moderately correlated with PA (p < 0.05), except in the male 5CM group. In the overweight/obesity group, muscle and fat-free mass (FFM) of the 5CM and 3CM correlated directly and moderately with blood fasting glucose (BFG) and BMD (p < 0.05), except in females, where FFM was not related to BMD but was related to residual mass (p < 0.01). Independent of gender and BMI, bone mineral content was positively and highly correlated with BMD (p < 0.0000). In the male overweight/obesity group, bone, skin, and residual mass were correlated with BFG (p < 0.05). In conclusion, for the assessment of non-athletic adult populations, more routine use of the 5CM in clinical practice is recommended.
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  • 文章类型: Journal Article
    进食障碍(ED)表现为饮食习惯或相关行为的持续中断,显着影响身体健康和社会心理健康。ED患者的营养评估对于监测治疗效果至关重要。虽然双能X射线吸收法(DEXA)仍然是标准的,对生物电阻抗矢量分析(BIVA)和营养超声®(NU)等替代方法的兴趣由于其可负担性和便携性而增加。此外,手测力法提供了一种用户友好的方法来评估握力(HGS),说明营养状况。进行了一项前瞻性研究,以评估BIVA的效用,NU®,43名女性AN患者的HGS。在基线和出院时进行测量。共有41名患者完成了研究。干预之后,许多与BIVA相关的参数,如脂肪(3.5±2kg与5.3±2.7kg,p<0.001)和游离脂肪量(33.9±3.8kg与37.5±4.1kg,p<0.001)部分恢复。同样,营养超声®在评估身体成分变化方面显示出有希望的结果,例如总腹部脂肪组织(0.5±0.3cm与0.9±0.3cm,p<0.05)。以同样的方式,股直肌横截面积值与游离脂肪量(0.883,p<0.05)和阑尾肌质量(0.965,p<0.001)等临床结局相关.HGS在干预后达到正常百分位数(21.6±9.1kgvs.25.9±12.3kg,p<0.05),证明握力与身体成分参数之间存在显着关联,例如游离脂肪量(0.658,p<0.001)和阑尾肌肉量(0.482,p<0.001)。合并BIVA-,NU®-,和HGS增强的营养评估为AN患者的治疗提供了具有成本效益的,便携式,和DEXA的非侵入性替代品。这些技术为身体成分和营养状况的变化提供了宝贵的见解,which,反过来,促进治疗监测,并有助于改善患者预后。
    Eating disorders (EDs) manifest as persistent disruptions in eating habits or related behaviors, significantly impacting physical health and psychosocial well-being. Nutritional assessment in ED patients is crucial for monitoring treatment efficacy. While dual-energy X-ray absorptiometry (DEXA) remains standard, interest in alternative methods such as bioelectrical impedance vector analysis (BIVA) and Nutritional Ultrasound® (NU) has risen due to their affordability and portability. Additionally, hand dynamometry offers a user-friendly approach to assessing grip strength (HGS), indicative of nutritional status. A prospective study was carried out to evaluate the utility of BIVA, NU®, and HGS in 43 female AN patients. Measurements were taken at baseline and hospital discharge. A total of 41 patients completed the study. After the intervention, numerous BIVA-related parameters such as fat (3.5 ± 2 kg vs. 5.3 ± 2.7 kg, p < 0.001) and free fat mass (33.9 ± 3.8 kg vs. 37.5 ± 4.1 kg, p < 0.001) were partially restored. Similarly, Nutritional Ultrasound® showed promising results in assessing body composition changes such as total abdominal fat tissue (0.5 ± 0.3 cm vs. 0.9 ± 0.3 cm, p < 0.05). In the same way, rectus femoris cross-sectional area values correlated with clinical outcomes such as free fat mass (0.883, p < 0.05) and appendicular muscle mass (0.965, p < 0.001). HGS reached the normality percentile after the intervention (21.6 ± 9.1 kg vs. 25.9 ± 12.3 kg, p < 0.05), demonstrating a significant association between grip strength and body composition parameters such as free fat mass (0.658, p < 0.001) and appendicular muscle mass (0.482, p < 0.001). Incorporating BIVA-, NU®-, and HGS-enhanced nutritional assessment into the treatment of AN patients offers cost-effective, portable, and non-invasive alternatives to DEXA. These techniques offer valuable insights into changes in body composition and nutritional status, which, in turn, facilitate treatment monitoring and contribute to improved patient outcomes.
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  • 文章类型: Journal Article
    这项系统评价和荟萃分析评估了临床医生主导和社区团体运动干预对成人2型糖尿病患者一系列健康结果的综合影响。我们的文献检索横跨Medline,Scopus,PubMed,Embase,和CINAHL数据库,重点关注2003年1月至2023年1月发表的同行评审研究.我们纳入了涉及18岁及以上参与者的研究,以及以英语发表的文章,产生了8项研究的数据集,938名参与者。跨越8项同行评审研究,938名参与者,分析的重点是干预措施对血糖控制的影响,身体健康,以及人体测量和血液学测量。与身体健康有关的结果,通过六分钟步行测试评估,30年代的坐立测试,和椅子坐姿测试,是从五项研究中提取的,所有这些都报告了改进。七项研究的人体测量结果强调了腰围和舒张压的积极变化;然而,体重指数等指标,收缩压,体重,静息心率没有明显变化。血液学结果,在四项研究中回顾,显示空腹血糖显着改善,甘油三酯,和总胆固醇,HbA1c水平的降低证明了血糖控制,但LDL和HDL胆固醇水平未受影响.评估的15项结果指标中有10项显示显着增强,这表明所实施的干预策略可以为管理关键的2型糖尿病相关健康参数提供实质性的健康益处.这些发现结合进一步的研究,可以为2型糖尿病患者的体育锻炼指南提供参考,倡导在社区环境中进行有监督的集体锻炼。
    This systematic review and meta-analysis evaluated the combined effects of clinician-led and community-based group exercise interventions on a range of health outcomes in adults with type 2 diabetes mellitus. Our literature search spanned Medline, Scopus, PubMed, Embase, and CINAHL databases, focusing on peer-reviewed studies published between January 2003 and January 2023. We included studies involving participants aged 18 years and older and articles published in English, resulting in a dataset of eight studies with 938 participants. Spanning eight peer-reviewed studies with 938 participants, the analysis focused on the interventions\' impact on glycemic control, physical fitness, and anthropometric and hematological measurements. Outcomes related to physical fitness, assessed through the six-minute walk test, the 30 s sit-to-stand test, and the chair sit-and-reach test, were extracted from five studies, all of which reported improvements. Anthropometric outcomes from seven studies highlighted positive changes in waist circumference and diastolic blood pressure; however, measures such as body mass index, systolic blood pressure, weight, and resting heart rate did not exhibit significant changes. Hematological outcomes, reviewed in four studies, showed significant improvements in fasting blood glucose, triglycerides, and total cholesterol, with glycemic control evidenced by reductions in HbA1c levels, yet LDL and HDL cholesterol levels remained unaffected. Ten of the fifteen outcome measures assessed showed significant enhancement, indicating that the intervention strategies implemented may offer substantial health benefits for managing key type 2 diabetes mellitus-related health parameters. These findings in combination with further research, could inform the refinement of physical activity guidelines for individuals with type 2 diabetes mellitus, advocating for supervised group exercise in community settings.
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  • 文章类型: Journal Article
    目的:该研究以人体测量学和心肺功能为特征,和心肺,对3×3分钟圆形(R)自由接触/战斗拳击模拟的生化和免疫反应,精英奥运拳击手(4名女性和10名男性)。方法:评估包括静息代谢率,人体测量,最大等级测试练习(第1次访问),自由战斗模拟(3×3分钟R,休息1分钟),之前采集的血样,战斗期间和之后(访问2)。结果:分别为,女性和男性有(平均值±SD;或中位数:非参数数据)体脂百分比(17.2[3.5]和4.6[0.8]%),主要是介晶体型分型,和V•O2MAX(50.0±2.5和56.2±5.2毫升。kg-1.min-1).自由战斗模拟导致高心血管应变[对应于R1的平均心率:92±3;R2:94±2;和R3:最大HR的95±2%]和指示酸中毒的血液化学(以下R3:7.21±0.08pH,碳酸氢盐13.1±3.6mmol。L-1,二氧化碳13.9±3.8mmol。L-1,乳酸15.1±3.8mmol。L-1和葡萄糖8.4±1.3mmol。L-1).Further,值得注意的一般分解代谢,战斗后模拟血液和免疫反应明显(R3后1小时:肌酐95.2±14.5µmol。L-1,尿素6.4±1.3mmol。L-1,白细胞积聚7.8±2.6×109。L-1,血红蛋白14.9±0.8g。dL-1和血细胞比容43.7±1.9%)。结论:从3×3自由战斗模拟中可以看到明显的心血管劳损和酸中毒,而R3后1小时明显的分解代谢和免疫反应。这种表征是男性和女性中的第一个(最近采用了3×3minR格式,由男性使用)精英奥林匹克拳击手,并提供了一个表征框架,以帮助从业者和运动员尝试为特定的条件训练设计提供循证实践。
    Purpose: The study characterized the anthropometrical and cardiorespiratory profile, and the cardiorespiratory, bio-chemical and immunological responses to 3 × 3 min round (R) free-contact/combat boxing simulation, in elite Olympic Boxers (4 female and 10 male). Methods: The evaluation consisted of resting metabolic rate, anthropometric measurement, maximal graded test exercise (visit 1), free combat simulation (3 × 3 min R, 1 minute rest), and blood samples collected before, during and after the combat (visit 2). Results: Respectively, females and males had (mean±SD; or median: for non-parametric data) body fat percentage (17.2[3.5] and 4.6[0.8]%), predominantly mesomorphic somatotyping, and V˙O2MAX (50.0 ± 2.5 and 56.2 ± 5.2 ml.kg-1.min-1). The free combat simulation resulted in high cardiovascular strain [mean heart rate corresponding to R1: 92 ± 3; R2: 94 ± 2; and R3: 95 ± 2% of maximal HR] and blood chemistry indicative of acidosis (following R3: 7.21 ± 0.08 pH, bicarbonate 13.1 ± 3.6 mmol.L-1, carbon dioxide 13.9 ± 3.8 mmol.L-1, lactate 15.1 ± 3.8 mmol.L-1, and glucose 8.4 ± 1.3 mmol.L-1). Further, notable general catabolism, hematological and immune responses were evident post combat simulation (1-hour post R3: creatinine 95.2 ± 14.5 µmol.L-1, urea 6.4 ± 1.3 mmol.L-1, white blood cell accumulation 7.8 ± 2.6 × 109.L-1, hemoglobin 14.9 ± 0.8 g.dL-1 and hematocrit 43.7 ± 1.9%). Conclusions: Notable cardiovascular strain and acidosis are seen from the 3 × 3 free combat simulation whilst pronounced catabolism and immune responses are evident 1-hour post R3. This characterization is the first in male and female (who recently adopted the 3 × 3 min R format, as used by males) elite Olympic boxers and provides a characterization framework to assist practitioners and athletes in their attempts to deliver evidence-informed practice for specific conditioning session design.
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  • 文章类型: Journal Article
    背景:鉴定是法医学的重要方面。身份识别起着至关重要的作用,特别是在高度分解的尸体中,残缺的尸体,和未公开和零碎的人类遗骸。性别的估计是人类识别的重要参数。在法医人体测量中,性别决定与骨骼的形态特征有关,比如头骨和下颌骨,锁骨,胸骨,肩胛骨,肱骨,骨盆骨,胸骨,和股骨。因为牙齿是耐腐的,认真分析牙齿可以证明对个体的可靠性别估计,尤其是当其他决定因素被分散或破坏时。
    目的:本研究的目的是探讨性别与口腔舌冠尺寸的关系。
    方法:研究样本由年龄在20至35岁之间的100名志愿者受试者(50名男性受试者和50名女性受试者)组成。使用海藻酸盐对牙齿进行印模,并通过浇筑牙齿来制备铸模。使用数字卡尺在牙模上测量两个颌骨的所有牙齿(第三磨牙除外)的颊舌参数。
    结果:使用SPSS软件(IBMCorp.,Armonk,NY),并概述为平均值和标准偏差(SD)。使用独立的学生t检验或非配对检验比较男性和女性组。这项研究的结果表明,两组(男性和女性)的28个牙列测量参数中的16个(第三磨牙除外)在男性组中高于女性组(p<0.05)。
    结论:舌状牙列测量参数可用于北印度人群的性别估计。
    BACKGROUND: Identification is an important aspect of forensic medicine. Identification plays an imperative role, especially in highly decomposed bodies, mutilated bodies, and undisclosed and fragmentary human remains. The estimation of sex is an essential parameter of human identification. In forensic anthropometry, sex determination is related to morphometric characteristics of skeletal bones, such as the skull and mandible, clavicle, sternum, scapula, humerus, pelvic bone, sternum, and femur. Since teeth are decay-resistant, conscientious analysis of teeth can accredit reliable sex estimation of an individual, especially when other determinants are fragmented or destroyed.
    OBJECTIVE: The aim of the study was to explore the association between sex and buccolingual crown dimensions of teeth.
    METHODS: The study sample consists of 100 volunteer subjects (50 male subjects and 50 female subjects) aged between 20 and 35 years. Alginate was used to take impressions of the teeth and the cast was prepared using pouring by dental stone. Measurements of buccolingual parameters of all the teeth (except the third molars) of both jaws were done on dental casts by using a digital caliper.
    RESULTS: Collected data were analyzed using SPSS software (IBM Corp., Armonk, NY) and were outlined as mean and standard deviation (SD). The male and female groups were compared using an independent Student\'s t-test or unpaired test. The results of this study revealed that 16 out of 28 odontometric parameters (except third molar) of the two groups (male and female) were higher in the male group as compared to the female group (p < 0.05).
    CONCLUSIONS: Buccolingual odontometric parameters can be used for sex estimation in the North Indian population.
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  • 文章类型: Journal Article
    目标:虽然益生菌,益生元和合生元已被证明具有健康益处,它们对心脏代谢危险因素的影响尚不清楚.因此,我们进行了一项全面审查,以检查它们在人体测量方面的有效性,心脏代谢和炎症标志物。
    方法:我们从七个电子数据库中检索到的期刊开始至2023年1月13日,对合格的系统综述进行了综述(CINAHL,EMBASE,ProQuest,PubMed,Scopus,科克伦图书馆,和WebofScience)。使用多重系统评估2(AMSTAR2)工具评估方法学质量,并将证据的确定性分为五类。对SRMA和主要研究水平的结果效应大小进行随机效应荟萃分析。使用校正的覆盖面积评估重叠制品的程度。
    结果:24篇系统综述,代表265项独特研究,包括1076个独特的效应大小和25,973个受试者。合生元显然在改善体重方面更有效(-1.91kg,95CI-3.45千克至-0.37千克,p=0.02),总胆固醇(-12.17mg/dl,95CI-17.89mg/dl至-6.46mg/dl,p<0.001),低密度脂蛋白(-12.26mg/dl,95CI-18.27mg/dl至-6.25mg/dl,p<0.01),腰围(-1.85厘米,95CI-2.77厘米至-0.94厘米,p<0.01),和空腹血糖(-9.68mg/dl,95CI-16.18mg/dl至-3.18mg/dl,p<0.01)。益生元在改善体重指数方面更有效(-0.34kg/m2,95CI-0.48kg/m2至-0.20kg/m2,p<0.01),和HOMA-IR(-0.92,95CI-1.91至0.07,p=0.06)。益生菌被证明在降低舒张压方面更有效(-1.34mmHg,95CI-2.14mmHg至-0.55mmHg,P<0.01)改善胰岛素水平变化(-0.84mIU/mL,95CI-1.27mIU/mL至-0.41mIU/mL,p<0.01),和身体脂肪的百分比(-0.66%,95CI-0.70%至-0.61%,p<0.01)。对于所有结果,证据的可信度被列为四级.
    结论:前,pro-,合生元可以显著提高人体测量指数,葡萄糖和脂质分布,血压,和肥胖个体的炎症标志物。虽然建议他们的补充剂对这个人群有希望,真正的临床影响取决于根据特定适应症定制这些干预措施,并根据个体患者的需求定制治疗策略.
    OBJECTIVE: Though probiotics, prebiotics and synbiotics have been shown to confer health benefits, their effects on cardiometabolic risk factors remain unclear. Therefore, we conducted an umbrella review to examine their effectiveness on anthropometric, cardiometabolic and inflammatory markers.
    METHODS: We conducted an umbrella review on eligible systematic reviews with meta-analysis (SRMA) published from journals\' inception till 13 January 2023 retrieved from seven electronic databases (CINAHL, EMBASE, ProQuest, PubMed, Scopus, The Cochrane Library, and Web of Science). Methodological quality was appraised using the Assessment of Multiple Systematic Reviews 2 (AMSTAR2) tool and certainty of evidence was graded into five classes. Random-effects meta-analyses were performed on outcome effect sizes at the SRMA and primary study levels. Extent of overlapping articles were evaluated using corrected cover area.
    RESULTS: 24 systematic reviews representing 265 unique studies, 1076 unique effect sizes and 25,973 subjects were included. Synbiotics were evidently more effective in improving weight (-1.91 kg, 95%CI -3.45 kg to -0.37 kg, p = 0.02), total cholesterol (-12.17 mg/dl, 95%CI -17.89 mg/dl to -6.46 mg/dl, p < 0.001), low-density lipoprotein (-12.26 mg/dl, 95%CI -18.27 mg/dl to -6.25 mg/dl, p < 0.01), waist circumference (-1.85 cm, 95%CI -2.77 cm to -0.94 cm, p < 0.01), and fasting plasma glucose (-9.68 mg/dl, 95%CI -16.18 mg/dl to -3.18 mg/dl, p < 0.01). Prebiotics were more effective in improving body mass index (-0.34 kg/m2, 95%CI -0.48 kg/m2 to -0.20 kg/m2, p < 0.01), and HOMA-IR (-0.92, 95%CI -1.91 to 0.07, p = 0.06). Probiotics were shown to be more effective in reducing diastolic blood pressure (-1.34 mmHg, 95%CI -2.14 mmHg to -0.55 mmHg, P < 0.01) improving insulin level change (-0.84 mIU/mL, 95%CI -1.27 mIU/mL to -0.41 mIU/mL, p < 0.01), and the percentage of body fat (-0.66%, 95%CI -0.70% to -0.61%, p < 0.01). For all outcomes, the credibility of evidence was classified as class IV.
    CONCLUSIONS: Pre-, pro-, and synbiotics can significantly enhance anthropometric indices, glucose and lipid profiles, blood pressure, and inflammatory markers in individuals confronting obesity. While suggesting their supplementation holds promise for this population, the true clinical impact hinges on tailoring these interventions to specific indications and customizing treatment strategies to align with individual patient needs.
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  • 文章类型: Journal Article
    背景:面部女性化手术(FFS)是最常见的面部性别确认手术形式。当前的知识差距之一是对跨性别和非二元患者的基线颅面规范中种族群体之间差异的理解。
    方法:纳入2018年至2023年期间在单一机构寻求FFS咨询并接受颅面计算机断层扫描(CT)扫描的所有患者。以前接受过面部手术的患者被排除在外。对患者特征进行了图表回顾,包括种族,年龄,激素治疗持续时间,和先前的性别确认手术。种族分类包括怀特,Latinx,非洲裔美国人,或亚洲人。排除具有其他或多种族身份的患者。下面部测量值来自术前面部CT扫描。对种族群体之间的所有测量进行了比较分析。
    结果:在这项研究中,包括204例患者,平均年龄为32.0±10.2岁,中位激素治疗持续时间为2.0年。种族之间的显着差异是:1。与所有其他种族组(p=0.03)相比,亚洲患者的Zygoma宽度最大(13.5±0.6cm),2.非洲裔美国患者的鼻唇沟角度最小(82.5±13.1度,p<0.001),3.在非裔美国患者中,较低的面部高度最大(6.9±0.7cm,p<0.001),和4。下颌外侧耀斑在非裔美国患者中最大(0.4±0.1cm),在Latinx患者中最小(0.2±0.1cm,p<0.001)。
    结论:应仔细考虑FFS的特定目标领域,以考虑可能的基线种族差异。相对面部比例也可能是跨性别和性别非二元患者中更重要的手术计划工具,而不是单独的绝对测量。
    BACKGROUND: Facial feminization surgery (FFS) is the most common form of facial gender-affirming surgery. One of the current knowledge gaps is the understanding of differences among racial groups in baseline craniofacial norms for transgender and nonbinary patients.
    METHODS: All patients who sought consultation for FFS and underwent craniofacial computed tomography (CT) scans at a single institution between 2018 and 2023 were included. Patients who underwent previous facial surgeries were excluded. Chart reviews were conducted for patient characteristics, including race, age, hormone therapy duration, and prior gender-affirming surgeries. Racial categorizations included White, Latinx, African American, or Asian. Patients with other or multiracial identities were excluded. Lower face measurements were derived from preoperative facial CT scans. Comparative analyses were performed on all measurements among the racial groups.
    RESULTS: In this study, 204 patients were included with an average age of 32.0 ± 10.2 years and a median hormone therapy duration of 2.0 years. The notable differences among the racial groups were: 1. Zygomatic width was the largest in Asian patients (13.5 ± 0.6 cm) compared to all other racial groups (p = 0.03), 2. Nasolabial angle was the smallest in African American patients (82.5 ± 13.1 degrees, p < 0.001), 3. Lower face height was the largest in African American patients (6.9 ± 0.7 cm, p < 0.001), and 4. Lateral mandibular flare was the largest in African American patients (0.4 ± 0.1 cm) and the smallest in Latinx patients (0.2 ± 0.1 cm, p < 0.001).
    CONCLUSIONS: Specific target areas of FFS should be carefully considered to account for possible baseline ethnic differences. Relative facial proportions may also be a more salient surgical planning tool in transgender and gender nonbinary patients rather than absolute measurements alone.
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