目的:评估前房深度(ACD)与晶状体厚度(LT)之间的关系,以及它的三个主要组成部分(前和后皮质和核厚度),在白内障和非白内障的眼睛中,取决于轴向长度(AxL)。
方法:晶状体的前后皮质和核厚度,ACD,使用光学低相干反射法在白内障和非白内障眼中测量AxL。它们也被归类为远视,正视,近视,和高度近视,取决于AxL;因此,创建了八个子组。每组的最小样本量为44眼(44例患者)。对整个样本和每个AxL亚组拟合线性模型,以评估晶状体变量和ACD之间的关系是否存在差异。包括年龄作为协变量。
结果:三百七十名白内障患者(237名女性,133名男性)和250名非白内障对照(180名女性,70名男性),年龄70.5±9.4和41.9±15.5岁,分别,被招募。平均AxL,ACD,白内障和非白内障眼的LT分别为23.90±2.05、24.11±2.11、2.64±0.45和2.91±0.49、4.51±0.38、3.93±0.44mm,分别。LT的反比关系,前皮质和后皮质,白内障和非白内障眼之间ACD的核厚度没有显着差异(p≥0.26)。取决于AxL的样品的进一步亚分类显示,对于任何非白内障AxL组,后皮质与ACD之间的反比关系不再显著(p>0.05)。LT,前皮质和后皮质,对于整个样本,白内障和非白内障眼之间的核厚度没有显着差异(p≥0.43),和所有AxL组在调整年龄后。
结论:白内障的存在不会改变LT的反比关系,前皮质和后皮质,和带有ACD的细胞核。这种关系似乎并不重要地取决于AxL。此外,LT的可能差异,前皮质和后皮质,白内障和非白内障眼睛之间的核可能不是由晶状体混浊引起的,但可能是由渐进的镜片生长引起的老化。
OBJECTIVE: To assess the relationship between anterior chamber depth (ACD) and lens thickness (LT), as well as its three main components (anterior and posterior cortex and nucleus thickness), in cataractous and non-cataractous eyes, depending on the axial length (AxL).
METHODS: Anterior and posterior cortex and nucleus thickness of the crystalline lens, ACD, and AxL were measured using optical low-coherence reflectometry in cataractous and non-cataractous eyes. They were also classified into hyperopia, emmetropia, myopia, and high myopia, depending on AxL; thus, eight subgroups were created. A minimum sample size of 44 eyes (of 44 patients) for each group was recruited. Linear models were fitted for the whole sample and each AxL subgroup to assess if there were differences in the relationships between the crystalline lens variables and ACD, including age as a covariate.
RESULTS: Three hundred seventy cataract patients (237 females, 133 males) and 250 non-cataract controls (180 females, 70 males), aged 70.5 ± 9.4 and 41.9 ± 15.5 years, respectively, were recruited. The mean AxL, ACD, and LT for the cataractous and non-cataractous eyes were 23.90 ± 2.05, 24.11 ± 2.11, 2.64 ± 0.45, and 2.91 ± 0.49, 4.51 ± 0.38, 3.93 ± 0.44 mm, respectively. The inverse relationship of LT, anterior and posterior cortex, and nucleus thickness with ACD was not significantly (p ≥ 0.26) different between cataractous and non-cataractous eyes. Further subclassification of the sample depending on AxL showed that the inverse relationship between the posterior cortex and ACD was no longer significant (p > 0.05) for any non-cataractous AxL group. LT, anterior and posterior cortex, and nucleus thickness was not significantly (p ≥ 0.43) different between cataractous and non-cataractous eyes for the whole sample, and all AxL groups after adjusting for age.
CONCLUSIONS: The presence of cataracts does not modify the inverse relationship of the LT, anterior and posterior cortex, and nucleus with ACD. And this relationship does not seem to depend importantly on AxL. Besides, the possible differences in LT, anterior and posterior cortex, and nucleus between cataractous and non-cataractous eyes may not be caused by lens opacification, but possibly by the progressive lens growth due to aging.