Liposarcomas are malignant tumors of adipocytes. The current report describes a liposarcoma in a 2.5-year-old, mixed-breed commercial sow that was detected during meat inspection. On gross examination, a firm, whitish, multinodular, 20 cm ×10 cm mass was observed in the perirenal area along with smaller nodules multifocally scattered within the renal parenchyma. Histological examination revealed an anaplastic sarcoma with clear intracytoplasmic lipidic vacuoles that were positive for Sudan black staining. Most of the cells were also positive for S100 and vimentin immunohistochemistry. Based on these results, a diagnosis of a perirenal liposarcoma was established. To the authors\' knowledge, no previous reports of liposarcomas in pigs have been published. This report also includes a review of the literature published on animal liposarcomas.