all-polyethylene tibia

  • 文章类型: Journal Article
    背景:尽管全聚乙烯胫骨组件具有潜在的优势,在全膝关节置换术(TKA)的美国市场上,模块化金属支撑组件的使用占主导地位。部分原因是由于缺乏全聚乙烯组件的模块化,对相关修订风险的担忧。这项研究利用美国关节置换登记处(AJRR)比较了全聚乙烯与模块化金属支撑胫骨组件的全因翻修和翻修感染的相关风险。
    方法:使用与2012年至2019年医疗保险和医疗补助服务中心数据相关的AJRR数据,对65岁及以上患者的原发性TKA病例进行了分析。分析比较了全聚乙烯与模块化金属背衬胫骨组件。我们确定了485,024例原发性TKA病例,由479,465(98.9%)金属背衬和5,559(1.1%)全聚乙烯组成。Cox比例风险回归分析创建了风险比(HR),以评估设计和全因修订风险的关联,同时调整性别,年龄和死亡的竞争风险。无事件生存曲线评估修正时间。
    结果:全聚胫骨组显示全因翻修风险降低(HR=0.37,95%CI[置信区间]:0.24~0.55,P<0.0001)和感染翻修风险降低(HR=0.41,95%CI:0.22~0.77,P<0.0001)。无事件生存曲线显示全因修正的风险降低,在不同时间点持续到TKA后8年。
    结论:在美国,与模块化金属背衬设计相比,TKA使用的全聚乙烯胫骨组件仍然很低。减少相关的修订风险应减轻对65岁或以上患者使用全聚乙烯组件的担忧,未来的调查应调查与扩大使用该人群相关的潜在成本和价值节省。
    BACKGROUND: Despite the potential advantage of all-polyethylene tibial components, modular metal-backed component use predominates the market in the United States for total knee arthroplasty (TKA). This is partially driven by concerns about the associated revision risk due to the lack of modularity with all-polyethylene components. This study utilized the American Joint Replacement Registry (AJRR) to compare the associated risk of all-cause revision and revision for infection for all-polyethylene versus modular metal-backed tibial components.
    METHODS: An analysis of primary TKA cases in patients aged 65 years and older was performed with AJRR data linked to Centers for Medicare and Medicaid Services data from 2012 to 2019. Analyses compared all-polyethylene to modular metal-backed tibial components. We identified 485,024 primary TKA cases, consisting of 479,465 (98.9%) metal-backed and 5,559 (1.1%) all-polyethylene. Cox proportional hazard regression analyses created hazard ratios (HRs) to evaluate the association of design and the risk of all-cause revision while adjusting for sex, age and the competing risk of mortality. Event-free survival curves evaluate time to revision.
    RESULTS: The all-polyethylene tibia group demonstrated a decreased risk for all-cause revision (HR = 0.37, 95% CI [confidence interval]: 0.24 to 0.55, P < 0.0001) and revision for infection (HR = 0.41, 95% CI: 0.22 to 0.77, P < 0.0001). Event-free survival curves demonstrated a decreased risk of all-cause revision that persisted across time points until 8 years post-TKA.
    CONCLUSIONS: In the United States, all-polyethylene tibial component use for TKA remains low compared to modular metal-backed designs. A decreased associated risk for revision should ease concerns about the use of all-polyethylene components in patients aged 65 years or older, and future investigations should investigate the potential cost and value savings associated with expanded use in this population.
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  • 文章类型: Journal Article
    Numerous studies have compared metal-backed components (MBTs) and all-polyethylene tibial components (APTs), but none of them specifically analysed the clinical results and the overall patient preference in patients who had undergone a staged bilateral knee replacement. The purpose of this study is to compare clinical results, perceived range of motion, and overall implant preference among patients who had undergone staged bilateral knee replacement with an APT and contralateral knee replacement with MBTs. A dataset of 62 patients from a single centre who underwent staged bilateral TKA between 2009 and 2022 was selected and retrospectively analysed. Tibial component removal was performed in three knees overall, all of which had MBTs. The mean measured Knee Score (KS) of knees with APTs was 78.37 and that of contralateral knees with MBTs was 77.4. The mean measured Function (FS) of knees with APTs was 78.22, and that of contralateral knees with MBs was 76.29. The mean flexion angle of knees with APTs was 103.8 and that for knees with MBTs was 101.04 degrees. A total of 54.8% of the patients preferred the knee that received APTs over contralateral MBTs. In our cohort, TKA with an APT in one knee and an MBT in the contralateral knee recorded similar clinical results and perceived ranges of motion. Patients in general preferred the knee that received an APT over contralateral knee with an MBT.
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  • 文章类型: Journal Article
    目的:由金属支持的胫骨(MBT)植入物产生的聚乙烯颗粒被认为是导致骨丢失和组件松动的原因。这个,加上先进的外科技术,改善材料和增加成本,对全聚乙烯胫骨(APT)重新产生了兴趣。我们调查了患者的APT周围骨矿物质密度(BMD),期望发现两个术后值之间没有差异。
    方法:65岁以上的患者,BMI≤37.5kg/m2,且之前未进行关节置换,使用APT进行计算机导航全膝关节置换术.研究队列(n=27)的平均年龄为71.9(SD4.35),BMI为31.2(SD3.8)。术后6周和18个月进行BMD检查。在前/后和外侧双能量X射线吸收测量扫描中确定了六个感兴趣区域(ROI)。对于每个ROI,确定了肢体之间的BMD相对差异(RD),并比较了两个时间点的RD。
    结果:没有发现任何ROI的RD之间的差异。未报告修订或并发症。术后18个月,79.2%的队列对他们的手术结果非常满意或满意,牛津膝关节评分与术前相比显着改善(p<0.001)。平均膝关节运动范围为102°(SD10.7°),平均腿部对齐为2.0°外翻(1-6°外翻)。
    结论:BMD分析结果表明,植入物固定良好,不影响功能。我们认为,对于不那么活跃的患者,使用APT和计算机导航是MBT的一个可行的更便宜的选择,具有较低的BMI和良好的骨骼质量。
    OBJECTIVE: Polyethylene particles produced from metal-backed tibial (MBT) implants are understood to contribute to bone loss and component loosening. This, along with advanced surgical techniques, improved materials and increasing costs, has renewed interest in all-polyethylene tibias (APTs). We investigated peri-APT bone mineral density (BMD) in patients, expecting to find no differences between two post-operative values.
    METHODS: Patients over 65 years, with BMI ≤ 37.5 kg/m2 and no previous joint replacements were recruited to have computer-navigated total knee arthroplasty using an APT. The study cohort (n = 27) had mean age of 71.9 (SD 4.35) and BMI of 31.2 (SD 3.8). The BMD examinations were performed 6 weeks and 18 months post-operatively. Six regions of interest (ROI) were identified on anterior/posterior and lateral dual-energy X-ray absorptiometry scans. For each ROI, BMD relative differences (RDs) were determined between limbs and RDs at the two time points were compared.
    RESULTS: No differences were found between the RDs for any ROI. No revisions or complications were reported. At 18 months post-operatively, 79.2% of the cohort were very satisfied or satisfied with the outcome of their surgery and Oxford Knee Scores improved significantly compared to pre-operatively (p < 0.001). Mean knee range of motion was 102° (SD 10.7°), and mean leg alignment was 2.0° valgus (1-6°valgus).
    CONCLUSIONS: Results from BMD analysis suggest that implants were well fixated without compromising function. We believe that using APTs with computer navigation is a viable cheaper option to MBTs for patients who are less active, have lower BMI and good bone quality.
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  • 文章类型: Journal Article
    先前的研究表明,模块化金属背衬胫骨(MBT)和全聚乙烯胫骨(APT)组件的存活率相同。这项研究的目的是比较美国大型数据库中APT和MBT组件的利用率和结果。
    查询了美国关节置换登记处,以确定2012年至2019年研究期间所有接受初次全膝关节置换术(TKA)的患者。根据胫骨组件(APT或MBT)将这些患者分为队列。队列人口统计数据,包括性别,医院规模,医院教学现状,区域,年龄,和Charlson合并症指数用描述性统计方法报告。总的再手术率和感染的修订,无菌性松动,假体周围骨折,在麻醉下操作,并使用国际疾病分类确定了其他原因的修订,第九次修订和当前程序术语代码,并比较了APT和MBT队列。根据APT和MBT再次手术的原因进行Kaplan-Meir生存分析。
    在研究期间,报告了703,007个TKAs,其中97.8%使用MBT,2.2%使用APT组件。尽管在研究期间引入了替代支付模式,APT的利用率从2012年的5.8%下降到2019年的1.7%。在整个研究期间,APT和MBTTKAs的生存率相似:在8年时分别为98.1%和98.6%。与MBT相比,APT的全因再手术率较高(1.36%vs1.00%;比值比1.52)。
    与MBT植入物相比,尽管它们的使用很少且成本较低,但APT在长达8年的时间内仍保持在0.4%的生存率之内。
    III级,回顾性。
    Previous studies have demonstrated equivalent survivorship of modular metal-backed tibial (MBT) and all-polyethylene tibial (APT) components. The purpose of this study is to compare the utilization and outcomes of APT and MBT components in a large US database.
    The American Joint Replacement Registry was queried to identify all patients undergoing primary total knee arthroplasty (TKA) during the study period from 2012 to 2019. These patients were divided into cohorts based on tibial component (APT or MBT). Cohort demographics including gender, hospital size, hospital teaching status, region, age, and Charlson Comorbidity Index were reported with descriptive statistics. Overall reoperation rates and revisions for infection, aseptic loosening, periprosthetic fracture, manipulation under anesthesia, and revision for other reasons were identified using International Classification of Diseases, Ninth Revision and Current Procedural Terminology codes and compared across APT and MBT cohorts. Kaplan-Meir survival analysis was performed based on reason for reoperation for APT and MBT.
    During the study period, 703,007 TKAs were reported with 97.8% utilizing MBT and 2.2% utilizing APT components. Despite the introduction of alternative payment models during the study period, the utilization of APT decreased from 5.8% in 2012 to 1.7% in 2019. The survival of APT and MBT TKAs were similar across the study period: 98.1% vs 98.6% at 8 years. The rate of reoperation for all-causes was higher for APT compared to MBT (1.36% vs 1.00%; odds ratio 1.52).
    Despite their paucity of use and lower cost APT remained within a 0.4% margin of survivorship when compared to MBT implants for up to 8 years.
    Level III, retrospective.
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  • 文章类型: Case Reports
    Limited literature exists on complications specific to the all-polyethylene tibial component in distal femoral replacement (DFR). Unlike in primary arthroplasty with polyethylene components, polyethylene granuloma has not been reported in DFR with an all-polyethylene tibia. Here, we report 2 cases of polyethylene granuloma in patients with primary bone sarcoma who underwent DFR with an all-polyethylene tibia. Radiologically, evidence of intraosseous granuloma formation and periprosthetic osteolysis was observed at the anterior tibial metaphysis. Both patients underwent an operative debridement of polyethylene granuloma and necrotic tissues, followed by a revision to a long-stem, cemented metal-backed tibia with impacted allograft to fill the defect. Polyethylene granuloma should be considered a differential diagnosis in the presence of a periprosthetic lytic lesion after DFR with an all-polyethylene tibial component.
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  • 文章类型: Comparative Study
    BACKGROUND: All-polyethylene (AP) tibial components have demonstrated equivalent or improved long-term survivorship and reduced cost compared with metal-backed (MB) components in primary total knee arthroplasty; however, there is a lack of data comparing these outcomes in the setting of an oncologic endoprosthetic reconstruction.
    METHODS: A total of 115 (88 AP:27 MB) patients undergoing cemented distal femur endoprosthetic reconstruction following oncologic resection were reviewed. Mean age was 40 years and 51% were females. Cumulative incidences of all-cause revision, tibial component revision, reoperation, and infection were calculated utilizing a competing risk analysis with death as the competitor. Mean follow-up was 14 years.
    RESULTS: The 10-year cumulative incidence of all-cause revision was 19.9% in the AP group and 16.3% in the MB group (hazard ratio [HR] = 0.93, p = 0.88). The cumulative incidence of tibial component revision was significantly lower in AP compared with MB at 10 years (1.1% vs. 12.5%, HR = 0.18, p = 0.03). There was no difference in infection-free survival when comparing the two groups (p = 0.72).
    CONCLUSIONS: Reconstruction utilizing an MB or AP tibia component resulted in equivalent overall outcome; however, the tibial component in the AP group was less likely to be revised. AP tibial component should be considered for all primary oncologic reconstructions in the distal femur. LEVEL OF EVIDENCE: Level III Therapeutic.
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  • 文章类型: Journal Article
    Total knee arthroplasty is a successful elective orthopedic procedure with an increasing number being undertaken. Original knee arthroplasties used an all-polyethylene tibia; however, with concerns over tibial loosening, the trend moved toward the metal-backed variety. Modern designs providing more conformity and changes in manufacturing of the polyethylene make it an equivalent but cheaper option.
    We analyzed the medium-term outcome in 1092 patients with an all-polyethylene tibial component in their total knee arthroplasty.
    Twenty-six patients had further surgery on their knee for a variety of reasons. Assessing reoperation for any reason, the 7-year survival rate was 96.96% with an overall infection rate of 0.37%. Seven-year survival analysis using aseptic loosening as a criteria was 99.28%. Both the Short Form 12 physical score and Western Ontario and McMaster Universities Osteoarthritis Index score significantly improved and was sustained at 7 years. Body mass did not correlate to either outcomes or complications.
    An all-polyethylene tibia in a total knee arthroplasty has good outcome data and high patient satisfaction with good survivorship in the medium term, coupled with potential cost-saving benefits.
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  • 文章类型: Journal Article
    The aim of this study is to investigate differences in implant requirement, outcomes, and re-revision when total knee arthroplasty (TKA) was performed following unicompartmental knee arthroplasties (UKAs) with metal-backed (MB) compared to all-polyethylene (AP) tibial components.
    Retrospective study of 60 UKAs converted to 60 TKAs at mean 7.3 years (0.1 to 17) after implantation in 55 patients (mean age, 64 [49-83]; 44% male): 44 MB and 16 AP. TKA implant requirement was investigated in addition to mode of failure, Oxford Knee Score, and TKA survival at mean 5.4 years (0.5 to 17).
    Progression of osteoarthritis was the commonest mode of failure in MB UKAs (P = .03) and unexplained pain in AP (P = .011) where revisions were performed earlier (4.8 ± 3.2 vs 8.2 ± 4.5, P = .012). In 56 of 60 (93%) cases, unconstrained TKA implants were used. The use of standard cruciate-retaining TKAs without augments or stems was less likely following MB UKA compared to AP (12 of 38 [32%] vs 10/14 [71%], P = .013). Specifically MB UKA implants were associated with more tibial stem use (P = .04) and more use of cruciate-substituting polyethylene (P = .05). There was no difference in the use of constrained implants. Multivariate analysis showed tibial resection depth to predict stem requirement. Seven were re-revised giving 7-year TKA survival: from MB UKA 70.3 (95% CI, 47.0 to 93.6) and from AP UKA 87.5 (95% CI, 64.6 to 100; P = .191).
    MB UKA implants increase the chances of a complex revision requiring tibial stems and cruciate substitution but reduce the chances of early revision compared to AP UKA which often fail early with pain.
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  • 文章类型: Journal Article
    BACKGROUND: Biomechanical studies have suggested that proximal tibial strain is elevated in UKAs incorporating all-polyethylene tibial components with concern that this leads to premature failure. This study reports minimum 10-year outcomes for a UKA incorporating an all-polyethylene tibial component to determine whether these concerns were realised.
    METHODS: 109 fixed bearing UKAs (97 patients, mean age 68 (range 48-87), 54/97 (56%) female) with all-polyethylene tibial components were followed up for ≥ 10 years with Oxford Knee Scores, Forgotten Joint Scores and Kaplan-Meier analysis. 106/109 implants were 7 mm, 3 were 9.5 mm.
    RESULTS: Ten-year survival was 85.5% (78.6-92.4 95% CI) with the end-point failure for any reason. Unexplained pain was the commonest mode of failure (6/17) followed by lateral compartment osteoarthritis (5/17) and tibial subsidence/loosening (4/17). Revision rate was highest at 2-5 years due to revisions for unexplained pain. Ten-year survival was worse in patients < 65 years old (p = 0.035), in those with BMI > 30 (p = 0.017) and in those with postoperative increases in medial tibial sclerosis (p < 0.001 log-rank). Implant malalignment was not significantly associated with failure. Radioisotope bone scans in 16 patients all remained \"hot\" at mean 6.1 years (range 2.1-11.5). Relative risk of failure in patients < 65 years was 2.9 (1.2-7.0 95% CI) and when BMI > 30 was 2.9 (1.2-6.9 95% CI). In those with intact UKAs at 10 years, mean Oxford Knee Score was 34.8 ± 10.7, Forgotten Joint Score was 37.9 ± 26.7 and 96% were satisfied with their knee.
    CONCLUSIONS: The high rate of early failure between 2 and 5 years in this all-polyethylene tibial component UKA did not persist in the long term. Though medial proximal tibial metabolic changes appear to persist they are not necessarily symptomatic. BMI > 30 and age < 65 years were significant risk factors for revision.
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  • 文章类型: Journal Article
    Biomechanical studies have suggested improved stress distribution in metal-backed (MB) compared to all-polyethylene (AP) tibias, but such potential benefits have not been realized clinically. The purpose of this investigation was to analyze the outcomes of AP components in patients with primary osteoarthritis and compare the results to those obtained with MB tibial components in total knee arthroplasty (TKA).
    We reviewed 11,653 patients undergoing primary TKA for osteoarthritis. There were 9999 (86%) MB (8470 modular and 1529 monoblock) and 1654 (14%) AP tibial components. All patients had at least 2 years of clinical follow-up with mean follow-up of 8 years (range, 2-30 years).
    Mean survivorship for all primary TKAs at the 5-year, 10-year, 15-year, and 20-year time points was 97%, 92%, 86%, and 78%. AP tibial components were found to have improved survivorship when compared to modular and monoblock MB counterparts (P < .0001). Likewise, AP tibial components were found to have lower rates of tibial component loosening (P < .0001), tibial osteolysis, and component fracture. Furthermore, the AP group had improved survival rates in most age-groups except <55 years where there was no difference. AP tibial components demonstrated improved survival for all body mass index (BMI) groups except in patients with a BMI ≤25 kg/m2 where there was no difference.
    AP tibial components had significantly improved implant survival across all age-groups and most BMI categories in patients who underwent TKA for osteoarthritis. Given these outcomes, AP tibias are a reasonable option, regardless of patient age and BMI.
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