UNASSIGNED: The variables of aerobic performance and aerobic capacity are of significant importance in maintaining intensity during a fight and also contribute to faster recovery between rounds in sports fighting in karate. Anaerobic performance is crucial for the execution of the techniques during high-intensity offensive or defensive actions that determine the outcome of a fight. The objective of this study was to assess the relationship between selected performance indicators of aerobic and anaerobic capacity to sports performance in karate.
UNASSIGNED: The study included six male karate athletes (age 28 ± 3 years, body mass 85.10 kg; height 185.5 cm), medalists from European and World championship, events in senior categories. The selection criteria included training experience and sports level. The Karate specific aerobic test (KSAT) was use in conjunction with heart rate monitoring and changes in blood lactate levels to diagnose special aerobic endurance parameters. To determine the level of anaerobic performance the Wingate test were choosed. Technical and tactical indicators (efficiency, effectiveness and activeness of the attack) were used to assess the sports skill level during competition.
UNASSIGNED: Based on the Spearman correlation coefficient results demonstrated statistically significant differences (rs = -0.81) with large effect size index between efficiency of the attack and average heart rate achieved in the test KSAT. Additionally statistically significant differences (rs = 0.81) with large effect size were demonstrated between the fatigue index and efficiency of the attack Furthermore, the selected indicators of special aerobic endurance parameters and anaerobic performance demonstrated a high degree of predictive validity in relation to the efficiency (rp = 0.960) and activity (rp = 0.927) of attacks.
UNASSIGNED: The high level of predictive validity confirmed the importance of a high level of anaerobic conditions for performance in karate. The low values of the average heart rate in relation to the efficiency of the attack confirm the high performance level of karate athletes in relation to special aerobic performance parameters. It was found that the effectiveness of the attack had no relation to the monitored parameters.

BACKGROUND: There is a need to identify the complex interplay between various physiological mechanisms in primary ciliary dyskinesia (PCD) and cystic fibrosis (CF). The study investigated the interaction between respiratory function, exercise capacity, muscle strength, and inflammatory and oxidant/antioxidant responses in patients with PCD and CF.
METHODS: The study included 30 PCD patients, 30 CF patients, and 29 age and sex-matched healthy subjects. Exercise capacity was assessed using the modified shuttle walk test (MSWT). Handgrip strength (HGS) was used to evaluate general muscle strength. Oxidative stress-inflammatory parameters were also assessed. Pulmonary function test was performed by spirometry. Regarding the forced expiratory volume in 1 second (FEV1) z-score, patients with PCD and CF were subdivided into normal, mild, and severe/moderate groups.
RESULTS: Forced vital capacity (FVC) z-scores were lower in PCD and CF patients than controls. FEV1, FEV1/FVC, peak expiratory flow (PEF), and forced mid expiratory flow (FEF25-75%) z-scores were lower in PCD than in the other groups. HGS was lower in both mild PCD and normal CF patients relative to the controls. MSWT distance was lower in severe/moderate PCD patients than controls. Catalase (CAT), glutathione S-transferase (GST), glutathione peroxidase (GPx), and malondialdehyde (MDA) levels did not differ significantly among the study groups, but superoxide dismutase (SOD) level in severe/moderate PCD, and glutathione (GSH) level in normal CF were higher than in controls. Interleukin-6 (IL-6) level was higher in patients with normal PCD and CF compared to the controls. IL-1β level was higher in PCD compared to controls. Additionally, correlations among these parameters were also determined in some patient groups.
CONCLUSIONS: Homeostasis related to respiratory function, aerobic performance, muscle strength, inflammatory response, and oxidant/antioxidant balance were affected in PCD and CF. Evaluating these mechanisms together may contribute to elucidating the pathophysiology of these rare diseases.

The aim of the present study was to investigate the effect of weighted vest on-field small-sided games (SSG) soccer training, during the in-season period, on body composition and soccer-specific performances, in young, trained soccer players. A counterbalance study design was adopted, in which the fourteen well-trained players (age: 19.1 ± 0.5 yrs, body mass: 70.3 ± 5.3 kg, body height: 180.3 ± 3.0 cm, body fat: 9.2 ± 4.1%) performed both the Interventional (Vest) and Control (Con) training routines (6 weeks/season; 5 training sessions/week; 1 match/week), in different occasions (winter/spring period). Con group followed a regular weekly training plan. When the Con group performed their intense training sessions, Vest group performed only the on-field SSGs training wearing a vest (12.5% of athletes\' body mass). All the evaluations were performed one week before and after each training period. Statistical analyses include repeated ANOVA and T-test (p < 0.05). Significant increases in sprinting, jumping, change of direction (COD), aerobic and anaerobic performances were observed only after Vest intervention (-4.7 ± 2.2% to 11.2 ± 4.2%; p < 0.05). Significant changes were observed only after Vest training, compared to Cont (p < 0.05). These results suggest that using a weighted vest, during the in-season, onfield SSG training two times/week induces greater increases in young soccer players\' sprinting, jumping, COD, aerobic and anaerobic performances.

This randomized, double-blinded, experimental study investigated the effects of a four-week daily pre-workout supplementation (200 mg caffeine, 3.3 g creatine monohydrate, 3.2 g β-alanine, 6 g citrulline malate, and 5 g BCAA) vs. placebo (isocaloric maltodextrin) on anaerobic (jumping, sprinting, agility, and the running-based anaerobic sprint test: RAST) and aerobic (Yo-Yo intermittent recovery test level 1) performance, as well as on body composition and selective muscle damage/health-related blood markers in well-trained basketball players during the in-season period. Eighteen basketball players (age: 24.4 ± 6.3 years, height: 185.7 ± 8.0 cm, weight: 85.7 ± 12.8 kg, body fat: 16.5 ± 4.2%) were randomly assigned into two groups: pre-workout supplement (PWS, n = 10) or placebo (PL, n = 8). PWS consumption increased aerobic performance (PWS: 8 ± 6%; PL: -2 ± 6%; p = 0.004) compared to PL. A significant decrease was observed in peak (F = 7.0; p = 0.017), average (F = 10.7; p = 0.005), and minimum power (F = 5.1; p = 0.039) following 4 weeks of supplementation in both groups. No other significant changes were observed between groups (p > 0.05). In conclusion, the consumption of the current PWS over a four-week period appears to positively influence the aerobic performance of well-trained basketball players during the in-season period. However, it does not appear to mitigate the observed decline in anaerobic power, nor does it affect performance in jumping, sprinting, and agility, or alter body composition or selective muscle damage/health-related blood markers.

BACKGROUND: Phase angle (PhA), obtained from the bioimpedance analysis, is widely used in clinical situations and in sports. This study evaluated the association between PhA with body composition and physical performance of handball athletes.
METHODS: 43 national-level players (22.19 ± 3.86 years) of both sexes were evaluated regarding anthropometry, body composition, squat (SJ) and countermovement (CMJ) jumps, handgrip strength, and cardiorespiratory fitness.
RESULTS: We verified a correlation between PhA of the whole body and fat-free mass (r = 0.511), body mass index (r = 0.307), and body fat % (r = -0.303). There was a positive correlation between PhA of the whole body and SJ (r = 0.376), CMJ (r = 0.419), and handgrip for the dominant hand (r = 0.448). Moreover, PhA of the upper limbs was more strongly correlated with handgrip for the dominant (r = 0.630) and non-dominant hand (r = 0.575) compared to PhA of the whole body considering both sexes. Similarly, segmental PhA had a stronger significant correlation with SJ (r = 0.402) and handgrip for the dominant hand (r = 0.482) in males, as well as CMJ (r = 0.602) in females, compared to PhA of the whole body.
CONCLUSIONS: PhA of the whole body was positively related to fat-free mass, body mass index, body fat %, and lower- and upper-limbs strength in handball athletes. Segmental PhA might be used as a tool for estimating lower and upper limbs performance considering the sex, in preference to the PhA of the whole body.

This study aimed to characterize the composition of lipids in the red blood cells (RBCs) of adolescent swimmers and correlate this lipidome with the aerobic performance of the athletes. Five experimental assessments were performed by 37 adolescent swimmers. During the first session, the athletes went to the laboratory facility for venous blood sampling. The critical velocity protocol was conducted over the 4 subsequent days to measure aerobic performance (CV), comprising maximal efforts over distances of 100, 200, 400, and 800 m in a swimming pool. RBCs were obtained and extracted for analysis using the liquid chromatography-high resolution mass spectrometry untargeted approach. A total of 2146 ions were detected in the RBCs, of which 119 were identified. The enrichment pathway analysis indicated intermediary lipids in the glycerophospholipid, glycerolipid, sphingolipid, linoleic acid, and alpha-linolenic metabolisms, as well as pentose and glucuronate interconversions. A significant impact of the intermediary lipids was observed for the glycerophospholipid metabolism, including phosphatidylethanolamine (PE), phosphatidylcholine (PC), 1-acyl-sn-glycero-3-phosphocholine, sn-glycerol 3-phosphate, and phosphatidic acid. Inverse and significant associations were observed for PE 18:2/18:3 (r = -0.39; p = 0.015), PC 18:3/20:0 (r = -0.33; p = 0.041), and phosphatidic acid 18:0/0:0 (r = -0.47; p = 0.003) with aerobic performance. Swimmers who exhibited higher levels of aerobic performance also had the lowest abundance of PE, PC, and phosphatidic acid.

BACKGROUND: The influence of genetic polymorphisms on athletic performance has been widely explored. This study investigated the interactions between the polymorphisms ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M/T) and their association with endurance and strength phenotypes in Brazilian swimmers.
METHODS: 123 athletes (aged 20-30 years) and 718 controls participated in the study. The athletes were divided into elite and sub-elite (N = 19 and 104, respectively) and strength and endurance experts (N = 98 and 25, respectively). Hardy-Weinberg equilibrium was observed in all groups.
RESULTS: Considering the ACE polymorphism, it was observed a higher frequency of the DD genotype than expected in the strength experts of the elite group, whereas the strength experts sub-elite athletes had a higher frequency of the ID genotype (χ2 = 8.17; p = 0.01). Subjects with XX genotypes of ACTN3 are more likely to belong to the athlete group when compared to the control group (OR = 1.79, p = 0.04). The DD homozygotes of the ACE are more likely to belong to the elite group with strength phenotypes than the group of sub-elite (OR = 7.96, p = 0.01) and elite strength experts compared to elite endurance (OR = 18.0, p = 0.03). However, no significant differences were observed in the allelic distribution of the polymorphisms evaluated when comparing Elite, sub-elite athletes and controls.
CONCLUSIONS: ACE and ACTN3 allele frequencies should be considered with regard to performance influencing factors in Brazilian swimmers.

This paper systematically reviews the latest evidence regarding Quercetin\'s (Q) effect following exercise performance, aerobic and anaerobic exercise, muscle-damaging bouts and highlights blood biomarkers associated with muscle damage and recovery. Google Scholar, Web of Science, and MedLine (PubMed) searches were conducted through July-December 2021. Peer-reviewed studies that investigated Q as a single ingredient or in combination with other ingredients at dosages of 500 mg - 3000 mg, ranging from 15 min-to-1 h prior to exercise bout or chronic dose (7 days - 8 weeks) of consumption were included. A total of 34 studies met the inclusion criteria for the review. Key results include significant performance improvements in the following: VO2max (n = 2), time to exhaustion (n = 4 articles), fatigue decrement (n = 1 article), muscle damage (n = 3 articles), strength, torque velocity, and neuromuscular performance (n = 3 articles), redox potential (n = 1 article), repeated sprint performance and oxygen extraction (n = 1). Q also caused a change in systemic biomarkers: decrease in creatine kinase (n = 2), c-reactive protein (n = 4), lactate dehydrogenase (n = 4), inflammatory markers (n = 3), lipid peroxidation (n = 3) in aerobic and anaerobic performance. Varied findings exist regarding the efficacy of Q supplementation on exercise performance and recovery outcomes. The source of Q, training status of subjects, and exercise protocol performed may contribute to the effectiveness of Q as an antioxidant, anti-inflammatory, or ergogenic agent in exercise.

BACKGROUND: The menstrual cycle and its impact on training and performance are of growing interest. However, evidence is lacking whether periodized exercise based on the menstrual cycle is beneficial. The primary purpose of this proposed randomized, controlled trial, the IMPACT study, is to evaluate the effect of exercise periodization during different phases of the menstrual cycle, i.e., comparing follicular phase-based and luteal phase-based training with regular training during the menstrual cycle on physical performance in well-trained women.
METHODS: Healthy, well-trained, eumenorrheic women between 18 and 35 years (n = 120) will be recruited and first assessed for physical performance during a run-in menstrual cycle at different cycle phases and then randomized to three different interventions: follicular phase-based training, luteal phase-based training, or regular training during three menstrual cycles. The training intervention will consist of high-intensity spinning classes followed by strength training. The menstrual cycle phases will be determined by serum hormone analysis throughout the intervention period. Assessment of aerobic performance (primary outcome) and muscle strength, body composition, and blood markers will be performed at baseline and at the end of the intervention.
CONCLUSIONS: With a robust methodology, this study has the potential to provide evidence of the differential effects of exercise periodization during different phases of the menstrual cycle in female athletes.
BACKGROUND: ClinicalTrials.gov NCT05697263 . Registered on 25 January 2023.

BACKGROUND: The use of inert gas rebreathing for the non-invasive cardiac output measurement has produced measurements comparable to those obtained by various other methods. However, there are no guidelines for the inert gas rebreathing method during a cardiopulmonary exercise test (CPET). In addition, there is also a lack of specific standards for assessing the non-invasive measurement of cardiac output during CPET, both for healthy patients and those suffering from diseases and conditions.
OBJECTIVE: This systematic review aims to describe the use of IGR for a non-invasive assessment of cardiac output during cardiopulmonary exercise testing and, based on the information extracted, to identify a proposed CPET report that includes an assessment of the cardiac output using the IGR method.
METHODS: This systematic review was conducted by PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analyses) guidelines. PubMed, Web of Science, Scopus, and Cochrane Library databases were searched from inception until 29 December 2022. The primary search returned 261 articles, of which 47 studies met the inclusion criteria for this review.
CONCLUSIONS: This systematic review provides a comprehensive description of protocols, indications, technical details, and proposed reporting standards for a non-invasive cardiac output assessment using IGR during CPET. It highlights the need for standardized approaches to CPET and identifies gaps in the literature. The review critically analyzes the strengths and limitations of the studies included and offers recommendations for future research by proposing a combined report from CPET-IGR along with its clinical application.