acute dental pain

急性牙痛
  • 文章类型: Practice Guideline
    背景:由美国牙科协会科学与研究所召集的小组,匹兹堡大学,和宾夕法尼亚大学进行了系统评价和荟萃分析,并制定了循证建议,用于简单和手术拔牙后急性牙痛的药物管理和临时管理(即,无法立即获得最终的牙科治疗)与青少年牙髓和根尖疾病有关的牙痛,成年人,和老年人。
    方法:小组进行了4次系统评价,以确定阿片类和非阿片类镇痛药的效果,局部麻醉药,皮质类固醇,和局部麻醉药治疗急性牙痛。面板使用了“建议分级”,评估,开发和评估方法,以评估证据的确定性和建议的等级,评估,制定和评估决策证据框架,以制定建议。
    结果:专家组使用现有的最佳证据制定了建议和良好实践声明。与阿片类药物相比,使用非阿片类药物存在有利的净平衡。特别是,与阿片类药物相比,非甾体类抗炎药单独使用或联合使用对乙酰氨基酚可能能更好地缓解疼痛,安全性更好.
    结论:非阿片类药物是治疗拔牙后急性牙痛和临时治疗牙痛的一线疗法。当一线治疗不足以减轻疼痛或存在非甾体类抗炎药禁忌症时,应保留阿片类药物的使用。临床医生应避免常规使用阿片类药物的处方,并且在向青少年和年轻人处方阿片类药物时应格外谨慎。
    A panel convened by the American Dental Association Science and Research Institute, the University of Pittsburgh, and the University of Pennsylvania conducted systematic reviews and meta-analyses and formulated evidence-based recommendations for the pharmacologic management of acute dental pain after simple and surgical tooth extraction(s) and for the temporary management (ie, definitive dental treatment not immediately available) of toothache associated with pulp and periapical diseases in adolescents, adults, and older adults.
    The panel conducted 4 systematic reviews to determine the effect of opioid and nonopioid analgesics, local anesthetics, corticosteroids, and topical anesthetics on acute dental pain. The panel used the Grading of Recommendations, Assessment, Development and Evaluation approach to assess the certainty of the evidence and the Grading of Recommendations, Assessment, Development and Evaluation Evidence-to-Decision Framework to formulate recommendations.
    The panel formulated recommendations and good practice statements using the best available evidence. There is a beneficial net balance favoring the use of nonopioid medications compared with opioid medications. In particular, nonsteroidal anti-inflammatory drugs alone or in combination with acetaminophen likely provide superior pain relief with a more favorable safety profile than opioids.
    Nonopioid medications are first-line therapy for managing acute dental pain after tooth extraction(s) and the temporary management of toothache. The use of opioids should be reserved for clinical situations when the first-line therapy is insufficient to reduce pain or there is contraindication of nonsteroidal anti-inflammatory drugs. Clinicians should avoid the routine use of just-in-case prescribing of opioids and should exert extreme caution when prescribing opioids to adolescents and young adults.
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  • 文章类型: Systematic Review
    背景:由美国牙科协会科学事务委员会召集的指南小组,美国牙科协会科学与研究所,匹兹堡大学牙科医学院,和宾夕法尼亚大学综合全球口腔健康中心进行了系统评价和荟萃分析,并为1次或更多次简单和手术拔牙后急性牙痛的药理学管理以及牙痛的临时管理制定了循证建议(即,当无法立即获得明确的牙科治疗时)与牙髓和分叉或儿童根尖疾病(<12岁)有关。
    方法:作者进行了系统评价,以确定镇痛药和皮质类固醇在治疗急性牙痛中的作用。他们使用了建议评估等级,开发和评估方法,以评估证据的确定性和建议的等级评估,制定和评估决策框架的证据,以制定建议。
    结果:小组在不同条件下提出了7项建议和5项良好实践声明。与不提供镇痛治疗相比,存在有利于单独使用非甾体抗炎药或与对乙酰氨基酚组合使用的小的有益净平衡。没有关于糖皮质激素对儿童手术拔牙后急性疼痛的影响的可用证据。
    结论:非阿片类药物,特别是非甾体抗炎药,如布洛芬和萘普生单独或与对乙酰氨基酚联合使用,建议用于治疗1次或多次拔牙后的急性牙痛(即,简单和手术)和儿童牙痛的临时管理(有条件推荐,非常低的确定性)。根据美国食品和药物管理局,儿童使用可待因和曲马多治疗急性疼痛是禁忌的。
    A guideline panel convened by the American Dental Association Council on Scientific Affairs, American Dental Association Science and Research Institute, University of Pittsburgh School of Dental Medicine, and Center for Integrative Global Oral Health at the University of Pennsylvania conducted a systematic review and meta-analyses and formulated evidence-based recommendations for the pharmacologic management of acute dental pain after 1 or more simple and surgical tooth extractions and the temporary management of toothache (that is, when definitive dental treatment not immediately available) associated with pulp and furcation or periapical diseases in children (< 12 years).
    The authors conducted a systematic review to determine the effect of analgesics and corticosteroids in managing acute dental pain. They used the Grading of Recommendations Assessment, Development and Evaluation approach to assess the certainty of the evidence and the Grading of Recommendations Assessment, Development and Evaluation Evidence to Decision framework to formulate recommendations.
    The panel formulated 7 recommendations and 5 good practice statements across conditions. There is a small beneficial net balance favoring the use of nonsteroidal anti-inflammatory drugs alone or in combination with acetaminophen compared with not providing analgesic therapy. There is no available evidence regarding the effect of corticosteroids on acute pain after surgical tooth extractions in children.
    Nonopioid medications, specifically nonsteroidal anti-inflammatory drugs like ibuprofen and naproxen alone or in combination with acetaminophen, are recommended for managing acute dental pain after 1 or more tooth extractions (that is, simple and surgical) and the temporary management of toothache in children (conditional recommendation, very low certainty). According to the US Food and Drug Administration, the use of codeine and tramadol in children for managing acute pain is contraindicated.
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  • 文章类型: Journal Article
    随着普通人群中哮喘发病率的增加,牙科专业人员需要能够识别控制不佳的哮喘的体征和症状,并相应地修改牙科治疗。预防急性哮喘恶化是关键。应提醒患者在每次牙科预约时携带救援吸入器。使用吸入性皮质类固醇治疗哮喘的患者患口腔念珠菌病的风险更大,口干症,和龋齿。定期就诊和良好的口腔卫生在这些人群中很重要。
    With increasing rates of asthma in the general population, dental professionals need to be able to recognize the signs and symptoms of poorly controlled asthma and modify dental treatment accordingly. Prevention of an acute asthma exacerbation is key. Patients should be reminded to bring their rescue inhaler with them to every dental appointment. Patients who are using inhaled corticosteroids to manage their asthma are at greater risk of oral candidiasis, xerostomia, and caries. Regular dental visits and good oral hygiene are important among this population.
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  • 文章类型: Meta-Analysis
    背景:作者评估了镇痛药治疗拔牙后急性疼痛和儿童不可逆性牙髓炎相关疼痛的临床效果。
    方法:作者搜索了MEDLINE,Embase,Cochrane中央控制试验登记册,和美国临床试验注册从开始到2020年11月。他们包括随机对照试验,比较任何药物干预措施和安慰剂在接受拔牙或经历不可逆牙髓炎的儿科参与者中的作用。经过重复筛选和数据抽象,作者进行了随机效应荟萃分析.他们使用Cochrane偏差风险2.0工具评估偏差风险,并使用建议评估等级评估证据的确定性,开发和评估方法。
    结果:作者纳入了6项随机对照试验,报告了8项比较。与对乙酰氨基酚相比,布洛芬可以减轻疼痛强度(平均差[MD],0.27分;95%CI,-0.13至0.68;低确定性)和安慰剂(MD,-0.19点;95%CI,-0.58~0.21;确定性低)。与安慰剂相比,对乙酰氨基酚可以减轻疼痛强度(MD,-0.13点;95%CI,-0.52~0.26;确定性低)。与单独使用对乙酰氨基酚相比,对乙酰氨基酚和布洛芬联合可能会降低疼痛强度(MD,-0.75点;95%CI,-1.22至-0.27;中等确定性)和单独布洛芬(MD,-0.01分;95%CI,-0.53至0.51;中等确定性)。关于不良反应的确定性证据非常低。
    结论:在治疗儿童急性牙痛时,一些单独或联合的药物干预措施可能提供有益的效果。关于使用镇痛药治疗不可逆牙髓炎的证据很少。
    The authors assessed the clinical effectiveness of analgesics to manage acute pain after dental extractions and pain associated with irreversible pulpitis in children.
    The authors searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and US Clinical Trials registry from inception through November 2020. They included randomized controlled trials comparing any pharmacologic interventions with each other and a placebo in pediatric participants undergoing dental extractions or experiencing irreversible pulpitis. After duplicate screening and data abstraction, the authors conducted random-effects meta-analyses. They assessed risk of bias using the Cochrane Risk of Bias 2.0 tool and certainty of the evidence using the Grading of Recommendations Assessment, Development and Evaluation approach.
    The authors included 6 randomized controlled trials reporting 8 comparisons. Ibuprofen may reduce pain intensity compared with acetaminophen (mean difference [MD], 0.27 points; 95% CI, -0.13 to 0.68; low certainty) and a placebo (MD, -0.19 points; 95% CI, -0.58 to 0.21; low certainty). Acetaminophen may reduce pain intensity compared with a placebo (MD, -0.13 points; 95% CI, -0.52 to 0.26; low certainty). Acetaminophen and ibuprofen combined probably reduce pain intensity compared with acetaminophen alone (MD, -0.75 points; 95% CI, -1.22 to -0.27; moderate certainty) and ibuprofen alone (MD, -0.01 points; 95% CI, -0.53 to 0.51; moderate certainty). There was very low certainty evidence regarding adverse effects.
    Several pharmacologic interventions alone or in combination may provide a beneficial effect when managing acute dental pain in children. There is a paucity of evidence regarding the use of analgesics to manage irreversible pulpitis.
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  • 文章类型: Journal Article
    冠状病毒大流行造成了全球公共卫生危机,主要机构和非紧急服务空前关闭。全国牙科医院的中断导致了解决患者牙科投诉的挑战。本研究旨在分析大流行期间门诊牙科就诊模式与三级保健医院大流行前相比的差异。这项回顾性研究是通过从口腔医学和放射科的诊断登记簿中检索患者数据进行的,为期一年。从2019年9月24日至2020年3月23日检索的数据被归类为大流行前期间,从2020年3月24日至2020年9月24日的数据被归类为大流行期间。关于年龄的患者数据,性别和临床诊断被记录并分为三大类:“急诊”,“紧急”和“选修”。在大流行前的7550名患者和大流行期间的4035名患者在研究期间访问了牙科医院。在“紧急牙科护理”类别下,在大流行前期间,大多数病例报告急性牙痛(71.0%),其次是蜂窝织炎和间隙感染(20.1%)和颌面部创伤(8.7%)。在大流行期间,急性牙痛包括所有急诊就诊(n=307).大流行期间紧急牙科就诊的比例明显高于大流行前。与大流行期间相比,大流行前期间的选择性牙科就诊明显更高。(P<0.001)。与大流行前相比,COVID-19大流行期间牙科就诊的门诊趋势发生了显著变化。在大流行期间,紧急牙科服务的使用率高于大流行前的对应服务。
    The coronavirus pandemic has caused a global public health crisis with an unprecedented shutdown of major establishments and non-emergency services. Disruptions across the country in dental hospitals led to challenges in addressing patient\'s dental complaints. The present study aimed to analyse the difference in the pattern of the Outpatient dental visits during the pandemic period in comparison to that of the pre-pandemic period in a tertiary care hospital. This retrospective study was carried out by retrieving the patient data from the diagnostic register of the Department of Oral Medicine and Radiology for a period of one year. The data that was retrieved from 24th September 2019 to 23rd March 2020 was categorized under the pre-pandemic period and the data from 24th March 2020 to 24th September 2020 was grouped under the pandemic period. Patient data regarding the age, gender and clinical diagnosis was recorded and categorized under three main categories: \"Emergency\", \"urgent\" and \"elective\". 7550 patients during pre-pandemic period and 4035 patients during the pandemic period visited the dental hospital during the study period. Under the \"emergency dental care\" category, during the pre-pandemic period, majority of the cases reported of acute dental pain (71.0%) followed by cellulitis and space infection (20.1%) and maxillofacial trauma (8.7%). During the pandemic period, acute dental pain consisted of all emergency visits (n = 307). The proportion of emergency dental visits during the pandemic were significantly higher than the pre-pandemic period. Elective dental visits were significantly higher during pre-pandemic period in comparison to the pandemic period. (P < 0.001). There was a notable change in the outpatient trend of the dental visits during the COVID-19 pandemic in comparison to the pre-pandemic period. Emergency dental services were utilized at a higher rate during the pandemic period in comparison to the pre-pandemic counterpart.
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