acute aortic occlusion

急性主动脉闭塞
  • 文章类型: Journal Article
    目的:急性主动脉闭塞(AAO),虽然罕见,具有很高的发病率和死亡率风险。快速识别和血运重建对于肢体和生命保护至关重要。我们介绍了一种使用开放式血栓切除术和血管内动脉支架移植物代替开放式旁路治疗AAO的混合方法。
    方法:本病例描述了一名77岁的男性,他出现了伴有感觉障碍的新发下肢疼痛,并被发现患有急性肾下主动脉闭塞。开放股动脉切开用于开放血栓切除术和血管内球囊闭塞的远端栓塞保护,并结合主动脉和双侧髂动脉支架置入术。
    结果:患者在术后第3天出院,症状缓解,随访1个月时无症状。
    结论:这种使用支架移植物的主动脉-髂动脉重建技术先前已在慢性主动脉-髂动脉闭塞性疾病的背景下进行了描述;然而,其在急性主动脉闭塞中的使用以前没有文献记载.此案例说明了AAO混合方法的安全性和可行性,特别是在生理上不适合开放血运重建的患者中。
    OBJECTIVE: Acute aortic occlusion (AAO), though rare, carries a high morbidity and mortality risk. Rapid recognition and revascularization are crucial for limb and life preservation. We present a case of a hybrid approach using open thrombectomy and endovascular arterial stent grafts in lieu of an open bypass for management of AAO.
    METHODS: This case describes a 77-year-old man who presented with new-onset lower extremity pain with associated sensory deficits and was found to have acute infrarenal aortic occlusion. Open femoral cutdown for open thrombectomy and distal embolic protection with endovascular balloon occlusion was combined with aortic and bilateral iliac artery stenting.
    RESULTS: The patient was discharged home on post-operative day 3 with resolution of his presenting symptoms and remains asymptomatic at 1-month follow-up.
    CONCLUSIONS: This technique of aorto-iliac reconstruction using stent grafts has previously been described in the setting of chronic aorto-iliac occlusive disease; however, its use has not been previously documented in the setting of acute aortic occlusion. This case illustrates the safety and feasibility of a hybrid approach to AAO, particularly in patients who are physiologically unfit for open revascularization.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    急性主动脉闭塞(AAOs)是罕见的血管紧急情况,具有高发病率和死亡率。表现出的体征和症状各不相同,但通常涉及下肢,包括斑驳的皮肤,踏板脉搏减少,麻痹,和剧烈的疼痛。及时的识别和成像是必要的,以防止快速恶化,会导致肢体丧失或死亡.治疗包括基于患者相关风险因素和凝块位置的手术或血管内介入。我们介绍了一名76岁的女性,她带着AAO到达急诊科,涉及肾下腹主动脉和双侧髂总动脉。通过对腹部和骨盆进行血管造影,进行有效的体格检查和利用计算机断层扫描,可以适当地识别AAO,并随后成功进行手术取栓。此病例报告强调了对下肢疼痛和虚弱患者进行快速临床和影像学评估的重要性。
    Acute aortic occlusions (AAOs) are rare vascular emergencies associated with high morbidity and mortality. Presenting signs and symptoms vary but typically involve the lower extremities and include mottled skin with diminished pedal pulses, paresis, and severe pain. Prompt recognition and imaging are necessary to prevent rapid deterioration, which can lead to loss of limb or death. Treatment includes surgical or endovascular interventions based on patient-associated risk factors and clot location. We present a 76-year-old female who arrived at the emergency department with an AAO involving the infrarenal abdominal aorta and bilateral common iliac arteries. Efficient physical examination and utilization of computed tomography with angiography of the abdomen and pelvis allowed for the appropriate recognition of the AAO and subsequent successful surgical embolectomy. This case report underscores the importance of an expeditious clinical and radiographic evaluation in patients presenting with lower extremity pain and weakness.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:急性主动脉闭塞(AAO)是一种罕见但严重的疾病,与显着的发病率和死亡率相关。
    目的:这篇综述提供了对AAO的急诊医学评估,包括介绍,评估,和基于当前证据的急诊科(ED)管理。
    结论:AAO是指由于血栓形成或栓塞导致的主动脉血流阻塞。这种情况主要影响60-70岁的老年人心血管合并症,最常见于急性肢体缺血的体征和症状。虽然胃肠道,肾脏,脊髓可能会受到影响。第一线成像模式包括胸部的计算机断层扫描血管造影,腹部,还有骨盆.ED复苏管理包括避免极端的血压或心率,维持正常的氧饱和度和正常血容量状态,肝素抗凝,疼痛控制。建议紧急咨询血管外科专家,以建立通过血管内或开放技术恢复缺血组织灌注的计划。受影响人群中存在的基线合并症以及缺血和再灌注损伤的高发生率使AAO患者在手术治疗后立即和延迟地处于并发症的高风险中。
    结论:了解AAO可以帮助急诊临床医生诊断和治疗这种罕见但破坏性疾病。
    Acute aortic occlusion (AAO) is a rare but serious condition associated with significant morbidity and mortality.
    This review provides an emergency medicine focused evaluation of AAO, including presentation, assessment, and emergency department (ED) management based on current evidence.
    AAO refers to obstruction of blood flow through the aorta due to either thrombosis or embolism. This condition primarily affects older adults ages 60-70 with cardiovascular comorbidities and most commonly presents with signs and symptoms of acute limb ischemia, though the gastrointestinal tract, kidneys, and spinal cord may be affected. The first line imaging modality includes computed tomography angiography of the chest, abdomen, and pelvis. ED resuscitative management consists of avoiding extremes of blood pressure or heart rate, maintaining normal oxygen saturation and euvolemic status, anticoagulation with heparin, and pain control. Emergent consultation with the vascular surgery specialist is recommended to establish a plan for restoration of perfusion to ischemic tissues via endovascular or open techniques. High rates of baseline comorbidities present in the affected population as well as ischemic and reperfusion injuries place AAO patients at high risk for complications in an immediate and delayed fashion after surgical management.
    An understanding of AAO can assist emergency clinicians in diagnosing and managing this rare but devastating disease.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    护理点超声(PoCUS)可用于检测和评估急诊科(ED)可疑患者的动脉瘤和/或腹主动脉夹层。尽管常规使用PoCUS评估可疑主动脉瘤和夹层的腹主动脉,关于其在急诊急性腹主动脉闭塞诊断中的应用的文献有限.这是一个案例,证明了PoCUS在确定患有已知高血压和糖尿病的71岁女性患者中的急性主动脉闭塞中的用途。患者出现中央腹痛和双侧下肢无力至ED。患者有多种鉴别诊断,包括腹主动脉急性闭塞。主动脉的PoCUS用于诊断ED中的急性腹主动脉闭塞。快速诊断加快了转诊给血管外科医生以进行明确的治疗。急性腹主动脉闭塞是一种时间敏感且危及生命的紧急情况。腹主动脉的PoCUS以检测急性腹部闭塞可以快速诊断,并有可能改善预后。标准主动脉PoCUS扫描中应包括检测急性腹主动脉闭塞的方案。
    Point-of-care ultrasound (PoCUS) can be used to detect and evaluate for an aneurysm and/or a dissection of the abdominal aorta in suspected patients in the Emergency Department (ED). Despite the routine use of PoCUS for the assessment of the abdominal aorta in suspected aortic aneurysms and dissections, there is limited literature regarding its use in the diagnosis of acute abdominal aortic occlusions in the emergency setting. This is a case demonstrating the use of PoCUS in identifying an acute aortic occlusion in a 71-year-old female patient with known hypertension and diabetes mellitus. The patient presented with central abdominal pain and bilateral lower limb weakness to the ED. The patient had multiple differential diagnoses, including a possible acute aortic occlusion of the abdominal aorta. PoCUS of the aorta was utilized to diagnose an acute abdominal aortic occlusion in the ED. The rapid diagnosis expedited the referral to vascular surgeons for definitive management. Acute abdominal aortic occlusion is a time-sensitive and life-threatening emergency. PoCUS of the abdominal aorta to detect acute abdominal occlusions allows for a rapid diagnosis with the potential to improve outcomes. A protocol for detecting acute abdominal aortic occlusion should be included in the standard aorta PoCUS scan.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    未经证实:马尾综合症(CES)通常是由椎间盘突出症的压迫性病因引起的,肿瘤,或脊柱骨折压迫鞘囊。这里,我们报告了CES模拟急性主动脉闭塞(AAO),一种与高发病率和高死亡率相关的罕见疾病。AAO可以损害脊髓血液供应并导致脊髓缺血。
    UNASSIGNED:我们的患者表现为双侧下肢疼痛和肠/膀胱尿失禁的急性发作,与CES有关的一系列症状。然而,在初始成像时,他的鞘囊没有压迫来解释他的症状。Further,调查显示AAO。患者接受了紧急主动脉血栓切除术,症状缓解。
    UNASSIGNED:AAO可以模拟CES,当影像学检查对任何脊柱压迫性病因阴性时,应在鉴别诊断中考虑。
    UNASSIGNED: Cauda equina syndrome (CES) is typically caused by a compressive etiology from a herniated disk, tumor, or fracture of the spine compressing the thecal sac. Here, we report a CES mimic - acute aortic occlusion (AAO), a rare disease that is associated with high morbidity and mortality. AAO can compromise spinal cord blood supply and leads to spinal cord ischemia.
    UNASSIGNED: Our patient presented with an acute onset of bilateral lower extremity pain and weakness with bowel/bladder incontinence, a constellation of symptoms concerning for CES. However, on initial imaging, there was no compression of his thecal sac to explain his symptomology. Further, investigation revealed an AAO. The patient underwent an emergent aortic thrombectomy with resolution of symptoms.
    UNASSIGNED: AAO can mimic CES and should be considered in one\'s differential diagnosis when imaging is negative for any spinal compressive etiologies.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    UNASSIGNED:本研究的目的是调查由急性主动脉闭塞(AAO)引起的双侧急性肢体缺血(BALI)的持续时间是否影响无截肢生存率。
    UNASSIGNED:对2010年1月1日至2019年1月1日因原发性肾下主动脉闭塞和BALI接受治疗的患者进行回顾性分析。使用单因素分析来确定不良结局的危险因素,并比较无截肢生存和无截肢生存组之间的BALI持续时间。
    UNASSIGNED:分析了16例平均年龄为70±11岁的患者的数据。以女性为主(56.3%,9/16)被纳入研究。16名患者中,九个有卢瑟福二级b级,七个人的入学成绩是卢瑟福三级.七名患者接受了血运重建的尝试,两人接受了初级截肢,七个人接受了初步缓解。无截肢存活组平均缺血时间明显短于无截肢存活组(7.4±3.5hvs22.4±16.3h,p=.01)。成功的双侧下肢血运重建的时间框架为<11h(p=0.03)。
    UNASSIGNED:由AAO引起的BALI持续时间<11h显示与无截肢生存率提高相关。
    UNASSIGNED: The purpose of this study was to investigate if the duration of bilateral acute limb ischaemia (BALI) caused by acute aortic occlusion (AAO) affected amputation-free survival.
    UNASSIGNED: A retrospective analysis of patients treated between 1 January 2010 and 1 January 2019 for primary occlusion of the infrarenal aorta and BALI was performed. Univariate analysis was used to determine the risk factors for adverse outcomes and compare the duration of BALI between the amputation-free survival and non-amputation-free survival groups.
    UNASSIGNED: The data from 16 patients with a mean age of 70 ± 11 years were analysed. Predominantly females (56.3%, 9/16) were included in the study. Out of 16 patients, nine had Rutherford grade IIb, and seven had Rutherford grade III at admission. Seven patients underwent revascularisation attempts, two underwent primary major amputation, and seven underwent primary palliation. The mean ischaemia time was significantly shorter in the amputation-free survival group than in the non-amputation-free survival group (7.4 ± 3.5 h vs 22.4 ± 16.3 h, p = .01). The time frame for successful bilateral lower limb revascularisation was <11 h (p = .03).
    UNASSIGNED: The duration of BALI due to AAO of <11 h was shown to be associated with improved amputation-free survival.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    最近的文献报道了与导致2019年冠状病毒病(COVID-19)感染的严重急性呼吸道综合征冠状病毒2(SARS-CoV-2)相关的血栓形成事件的高患病率。尽管静脉血栓栓塞并发症已得到充分研究,动脉血栓形成的描述较少。我们的目的是描述急性主髂动脉闭塞(AAO),本身是一种罕见的情况,作为COVID-19感染的并发症,并回顾有关其表现和可用治疗方式的现有文献。在2021年底的2周内,有2名近期感染COVID-19的患者与AAO一起向我们的三级护理医院就诊。每个病例都采用多模式治疗方法,包括血管介入放射学引导的溶栓,血管外科方法,和全身抗凝。尽管采取了两种不同的主要方法,在这两种情况下,每一种都导致高发病率和高死亡率。急性主动脉闭塞是一种罕见的疾病,发病率和死亡率高。COVID-19进一步与动脉血栓栓塞并发症有关,包括AAO,如这里介绍的。需要更多的研究来确定COVID-19感染后发生动脉血栓栓塞性疾病的风险最高的患者,并确定理想的治疗选择,以提高与这种并发症相关的极高的发病率和死亡率。
    Recent literature has reported a high prevalence of thrombotic events associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for causing coronavirus disease 2019 (COVID-19) infection. Although venous thromboembolism complications have been well studied, arterial thrombosis is less well described. Our aim is to describe acute aortoiliac occlusion (AAO), itself a rare condition, as a complication of COVID-19 infection and review existing literature regarding its presentation and available treatment modalities. Over a 2-week span in late 2021, 2 patients with recent COVID-19 infection presented to our tertiary care hospital with AAO. Each case was treated with a multimodal therapeutic approach, including vascular interventional radiology guided thrombolysis, vascular surgical approach, and systemic anticoagulation. Although two separate primary approaches were taken, each resulted in high morbidity and death in both cases. Acute aortic occlusion is a rare disease associated with high morbidity and mortality. COVID-19 has further been associated with arterial thromboembolic complications, including AAO, as presented here. More research is needed to identify patients at highest risk of developing arterial thromboembolic disease after COVID-19 infection as well as to determine ideal therapeutic options in order to improve the exceedingly high morbidity and mortality associated with this complication.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)或COVID-19是导致2019年全球大流行的病毒。COVID-19的肺部并发症在文献中得到了证实。然而,这种病毒会引起许多肺外表现,尤其是急性主动脉闭塞(AAO)。COVID-19通过上调血管内皮细胞中多种促凝血细胞因子而产生高凝状态。我们介绍了一名63岁的患者,该患者先前没有血栓形成前疾病史,该患者在COVID-19收缩后在远端腹主动脉和双侧髂总动脉中出现AAO。该患者是不良的手术候选者,并接受了通过EkoSonic™血管内系统(EKOS)导管使用双侧经股入路给予的纤维蛋白溶解剂治疗。此病例突出了AAO非手术候选人的独特治疗选择。
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 is the virus responsible for the 2019 global pandemic. Pulmonary complications of COVID-19 are well established in the literature. However, the virus causes numerous extrapulmonary manifestations, notably acute aortic occlusion (AAO). COVID-19 creates a hypercoagulable state via the upregulation of numerous procoagulant cytokines in endothelial cells of blood vessels. We present a case of a 63-year-old patient without a previous history of prothrombotic disorders who developed AAO in the distal abdominal aorta and bilateral common iliac arteries after contracting COVID-19. The patient was a poor surgical candidate and was treated with fibrinolytics that were administered via an EkoSonic™ Endovascular System (EKOS) catheter using a bilateral transfemoral approach. This case highlights a unique treatment option for non-surgical candidates with AAO.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

  • 文章类型: Case Reports
    背景:急性主动脉闭塞是一种罕见的疾病,需要早期诊断以帮助防止相当大的发病率和死亡率。典型的临床表现,比如急性下肢疼痛,急性瘫痪,没有踏板脉冲,可能被各种潜在的医疗条件掩盖。
    方法:我们介绍了一个精神状态改变的患者,体温过低,口腔和直肠温度测量之间存在很大差异,最终被诊断为主动脉闭塞。此病例报告描述了急性主动脉闭塞病例中口腔和直肠温度之间的显着差异。为什么急诊医生应该意识到这一点?:急性主动脉闭塞是一种真正的血管急症,如果没有早期干预,会导致肢体缺血,肠坏死,瘫痪或死亡。急诊医师应考虑患者的急性主动脉闭塞,口腔和直肠温度测量之间存在显着差异,否则临床评估有限。
    BACKGROUND: Acute aortic occlusion is a rare condition that requires early diagnosis to help prevent considerable morbidity and mortality. Typical clinical findings, such as acute lower extremity pain, acute paralysis, and absent pedal pulses, may be masked by a variety of underlying medical conditions.
    METHODS: We present a patient with altered mental status, hypothermia, and a large discrepancy between oral and rectal temperature measurements, who was ultimately diagnosed with aortic occlusion. This case report describes a marked difference between oral and rectal temperatures in a case of acute aortic occlusion. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Acute aortic occlusion is a true vascular emergency that, without early intervention, can lead to limb ischemia, bowel necrosis, paralysis, or death. Emergency physicians should consider acute aortic occlusion in a patient with a marked difference between oral and rectal temperature measurements who otherwise has a limited clinical evaluation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

公众号