acupuncture and moxibustion

针灸
  • 文章类型: Journal Article
    To explore the research hotspot, development trend and existing problem of artificial intelligence (AI) application in the field of acupuncture and moxibustion by using bibliometric method. Relevant articles of AI application in the field of acupuncture and moxibustion published in CNKI, Wanfang, VIP, PubMed and Web of Science from the database establishment to September 17, 2023 were searched. Excel 2019, CiteSpace 6.2.R4 and VOSviewer 1.6.19 were used to draw visual map of the number of publication, authors, research institutions and keywords, and further analyzed the research hotspot and trend. A total of 443 Chinese articles and 68 English articles were included. The number of annual publication of Chinese articles showed an overall increasing trend, while the number of publication of English articles was less, with a growing trend from 2020. Keywords analysis showed that \"Machine learning\", \"neural network\", \"deep learning\", \"data mining\", \"robot\" and other AI technologies were developing around acupuncture and moxibustion diagnosis and treatment of disease, efficacy prediction, teaching and intelligent equipment development. However, the research on the application of AI in the field of acupuncture and moxibustion is in the preliminary stage of development, and in the future, it is necessary to strengthen the communication and cooperation among the teams, to further explore the AI system in line with the characteristics of acupuncture and moxibustion diagnosis and treatment, and to promote the development of the digitalisation, intellectualisation and industrialisation of acupuncture and moxibustion.
    采用文献计量学方法探究人工智能(AI)在针灸领域应用的研究热点、发展趋势及存在的问题。检索自建库至2023年9月17日发表于中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)和维普中文期刊服务平台(VIP),PubMed和Web of Science(WOS)的AI在针灸领域应用相关文章。利用Excel 2019、 CiteSpace 6.2.R4、VOSviewer 1.6.19软件绘制发文量、作者、研究机构和关键词的可视化图谱,进一步分析该领域的研究热点和趋势。共纳入中文文献443篇、英文文献68篇。中文文献年发文量总体呈上升趋势,英文文献发文量较少,从2020年后开始出现增长趋势。关键词分析显示,“机器学习”“神经网络”“深度学习”“数据挖掘”“机器人”等AI技术正围绕着针灸诊疗疾病、疗效预测、教学、智能设备研发等方面展开。但AI在针灸领域应用研究处于初步发展阶段,未来各团队之间需加强交流合作,进一步探索符合针灸诊疗特色的人工智能系统,促进针灸数字化、智能化、产业化的发展。.
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  • 文章类型: Journal Article
    目的:研究针灸对胃癌患者化疗后并发症和不良事件的影响。通过对现有随机对照试验(RCT)的荟萃分析,本研究旨在加强证据基础,帮助研究者进一步了解艾灸和针刺对GC患者术后并发症和化疗不良事件的影响.
    方法:Embase,WebofScience,PubMed,科克伦图书馆,中国国家知识基础设施(CNKI),万方数据库,检索中国技术期刊VIP数据库,收集针灸对接受手术和化疗的GC患者胃肠功能和AE的影响的随机对照试验。结果测量包括术后胃肠道恢复(肠鸣音恢复时间,第一次排气/排便/进食的时间),AEs的发生率(恶心和呕吐,腹胀,和腹泻),骨髓抑制(白细胞,血红蛋白,和血小板),免疫功能指标(CD3+和CD4+)。为了评估质量,利用了Cochrane偏差风险工具。实施ReviewManager5.4进行荟萃分析。
    结果:15个符合条件的RCTs涉及1259例患者。Meta分析结果显示实验组肠鸣音恢复时间明显缩短(MD=-14.57,95%CI=[-18.97,-10.18],P<0.00001),至首次排气的时间(MD=-17.56,95%CI=[-22.23,-12.88],P<0.00001),首次排便时间(MD=-17.05,95%CI=[-21.02,-13.09],P<0.00001),和第一次进食时间(MD=-23.49,95%CI=[-28.81,-18.17],P<0.00001)高于对照组。恶心和呕吐的发生率显着降低(RR=0.46,95%CI=[0.21,1.02],P=0.05)和腹胀(RR=0.45,95%CI=[0.27,0.75],与对照组相比,实验组观察到P=0.002)。与对照组相比,实验组的白细胞计数显着增加(MD=0.89,95%CI=[0.23,1.55],P=0.008)。实验组的CD3+水平显著升高(MD=7.30,95%CI=[1.86,12.74],P=0.009)和CD4+(MD=2.75,95%CI=[1.61,3.90],P<0.00001)高于对照组。
    结论:在GC患者中,针灸可以帮助胃肠功能恢复,降低手术和化疗的AE发生率,提高免疫功能。
    OBJECTIVE: The impact of acupuncture and moxibustion on postoperative complications and adverse events (AEs) of chemotherapy in patients with gastric cancer (GC) has been investigated. Through a meta-analysis of existing randomized controlled trials (RCTs), this study sought to strengthen the evidentiary basis to help investigators further understand the effects of moxibustion and acupuncture on postoperative complications and AEs of chemotherapy among GC patients.
    METHODS: Embase, Web of Science, PubMed, The Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and VIP Database for Chinese Technical Periodicals were searched to collect RCTs on effects of acupuncture and moxibustion on gastrointestinal function and AEs among GC patients undergoing surgery and chemotherapy. Outcome measures included postoperative gastrointestinal recovery (bowel sound recovery time, time to first flatus/defecation/feeding), the incidence of AEs (nausea and vomiting, abdominal distension, and diarrhea), myelosuppression (white blood cells, hemoglobin, and platelet), and immune function indicators (CD3+ and CD4+). To assess quality, the Cochrane Risk of Bias Tool was utilized. Review Manager 5.4 was implemented to do the meta-analysis.
    RESULTS: Fifteen eligible RCTs involved 1259 patients. Meta-analysis results showed that the experimental group had a significantly shorter bowel sound recovery time (MD =  - 14.57, 95% CI = [- 18.97, - 10.18], P < 0.00001), time to first flatus (MD =  - 17.56, 95% CI = [- 22.23, - 12.88], P < 0.00001), time to first defecation (MD =  - 17.05, 95% CI = [- 21.02, - 13.09], P < 0.00001), and time to first feeding (MD =  - 23.49, 95% CI = [- 28.81, - 18.17], P < 0.00001) than the control group. There were significant decreases in the incidence of nausea and vomiting (RR = 0.46, 95% CI = [0.21, 1.02], P = 0.05) and abdominal distension (RR = 0.45, 95% CI = [0.27, 0.75], P = 0.002) observed in the experimental group in comparison with the control group. The experimental group demonstrated a significant increase in white blood cell counts in comparison with to the control group (MD = 0.89, 95% CI = [0.23, 1.55], P = 0.008). The experimental group showed significantly higher levels of CD3+ (MD = 7.30, 95% CI = [1.86, 12.74], P = 0.009) and CD4+ (MD = 2.75, 95% CI = [1.61, 3.90], P < 0.00001) than the control group.
    CONCLUSIONS: Among GC patients, acupuncture and moxibustion can aid in gastrointestinal function recovery, reduce the incidence of AEs of surgery and chemotherapy, and improve immune function.
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  • 文章类型: Journal Article
    OBJECTIVE: To analyze the rules of acupoint selection in treatment of cancer-related insomnia with acupuncture and moxibustion by data mining technology.
    METHODS: The articles of cancer-related insomnia treated with acupuncture and moxibustion were searched from CNKI, Wanfang, VIP, SinoMed, PubMed, WOS, Cochrane, and Embase databases, from the inception of each database to January 5, 2024. The prescription database of acupuncture and moxibustion for cancer-related insomnia was established. The descriptive analysis was conducted on the use frequency, meridian tropism and distribution of acupoints. Using SPSS Modeler 18.0 Apriori algorithm, the association rules of acupoint prescriptions were analyzed. With Cytoscape3.9.1 software used, the complex network diagram was plotted, and the cluster analysis of high-frequency acupoints was performed by SPSS26.0 software.
    RESULTS: Forty-one articles were included, and 67 prescriptions were extracted with 89 acupoints involved, and the total use frequency was 447 times. The top 4 acupoints of the high use frequency were Baihui (GV20), Sanyinjiao (SP6), Shenmen (HT7) and Shenting (GV24). The included meridians were the governor vessel, the spleen meridian, the bladder meridian, the conception vessel, the heart meridian and the stomach meridian. The selected acupoints were mostly distributed on the head, the neck and and the upper and lower limbs. The special acupoints of the high use frequency included the five-Shu points, the crossing points and yuan-primordial points. Regarding acupoint combination, GV24, SP6, HT7, and GV20 were highly correlated. The three effective clusters were categorized among the top 12 acupoints of the high use frequency.
    CONCLUSIONS: In treatment of cancer-related insomnia with acupuncture and moxibustion, the principle focuses on supporting the healthy qi, eliminating pathogens, regulating yin and yang, promoting the circulation of the governor vessel for regulating the spirit, and tranquilizing the mind. The core acupoint prescription may includes GV24, SP6, HT7 and GV20;combined with Zusanli (ST36) and Yintang (GV4+) to enhance the therapeutic effect.
    目的: 运用数据挖掘技术分析针灸治疗肿瘤相关性失眠的选穴规律。方法: 检索中国知网、万方、维普、PubMed等数据库从建库至2024年1月5日针灸治疗肿瘤相关性失眠的相关文献,建立针灸治疗肿瘤相关性失眠的处方数据库,对使用频次、归经、分布等进行描述性分析,运用SPSS Modeler18.0 Apriori算法对处方进行关联规则分析,Cytoscape3.9.1软件绘制复杂网络图,SPSS26.0软件对高频腧穴进行聚类分析。结果: 纳入文献41篇,提取针灸处方67条,涉及腧穴89个,总频次447次;腧穴使用频次排名前4位的是百会、三阴交、神门、神庭;所选经脉主要是督脉、脾经、膀胱经、任脉、心经、胃经等;选穴多集中在头项部和上、下肢部;特定穴中使用频次较高的为五输穴、交会穴、原穴;腧穴配伍中,神庭-三阴交-神门-百会四穴关联最强;前12位高频腧穴可分为3个有效聚类群。结论: 针灸治疗肿瘤相关性失眠以扶正固本、兼以祛邪、燮理阴阳、通督调神、宁心安神为治疗原则,核心穴组为神庭-三阴交-神门-百会,还可加用足三里、印堂以增强治疗效果。.
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  • 文章类型: Journal Article
    OBJECTIVE: To investigate the mechanism of the effect of acupuncture and moxibustion on improving liver injury in cisplatin (DDP) induced liver injury model mice by observing the changes of inositol-requiring enzyme (IRE) -1 signaling pathway.
    METHODS: Forty KM mice were randomly divided into control, model, acupuncture and moxibustion groups, with 10 mice in each group. The liver injury model was replicated by intraperitoneal injection of DDP (10 mg/kg). In the acupuncture group and the moxibustion group, acupuncture and moxibustion were performed at \"Dazhui\"(GV14), and bilateral \"Ganshu\"(BL18), \"Shenshu\" (BL23), and \"Zusanli\"(ST36), respectively for 6 min, once per day for 7 d. The apoptosis of hepatocytes was detected by TUNEL staining. The expression of phosphorylation(p)-IRE-1α, glucose-regulated protein (Grp) 78 and cysteine aspartic protease (Caspase) -12 in liver tissue were detected by immunohistochemistry and Western blot, respectively. The expression levels of Grp78 and Caspase-12 mRNA in liver tissue were detected by quantitative real-time PCR.
    RESULTS: Compared with the control group, the apoptosis rate of hepatocytes was increased (P<0.05), the positive expression and protein expression of p-IRE-1α, Grp78, and Caspase-12 were increased (P<0.05), the expression levels of Grp78 and Caspase-12 mRNA were increased (P<0.05) in the model group. Compared with the model group, all these indicators showed opposite trends (P<0.05) in the acupuncture and moxibustion groups.
    CONCLUSIONS: Acupuncture and moxibustion can reduce liver injury due to DDP chemotherapy by modulating IRE-1 signaling pathway, inhibiting the excessive activation of endoplasmic reticulum stress, and reducing liver cell apoptosis.
    目的: 基于与肝细胞内质网应激反应相关的肌醇需求酶(IRE)-1信号通路,探讨“扶正益肝”针灸穴方改善顺铂(DDP)所致小鼠肝损伤的作用机制。方法: 昆明种小鼠随机分为空白组、模型组、针刺组和艾灸组,每组10只。一次性腹腔注射DDP(10 mg/kg)复制肝损伤模型。针刺组和艾灸组分别选取“大椎”“肝俞”“肾俞”“足三里”进行针刺、艾灸治疗,每次6 min,1次/d,治疗7 d。采用TUNEL染色检测肝细胞凋亡情况,免疫组织化学法、Western blot法检测肝组织中磷酸化(p)-IRE-1α、葡萄糖调节蛋白(Grp)78、半胱氨酸天冬氨酸蛋白酶(Caspase)-12的表达,实时荧光定量PCR法检测肝组织中Grp78、Caspase-12 mRNA表达。结果: 与空白组比较,模型组小鼠肝细胞凋亡率升高(P<0.05),肝组织中p-IRE-1α、Grp78、Caspase-12阳性表达和蛋白表达升高(P<0.05),Grp78、Caspase-12 mRNA相对表达量升高(P<0.05)。与模型组比较,针刺组、艾灸组小鼠肝细胞凋亡率降低(P<0.05),肝组织中p-IRE-1α、Grp78、Caspase-12阳性表达和蛋白表达降低(P<0.05),Grp78、Caspase-12 mRNA相对表达量降低(P<0.05)。结论: “扶正益肝”针灸穴方可能通过调控IRE-1信号通路,抑制内质网应激的过度激活,减轻肝细胞凋亡,从而改善DDP化疗所致的肝损伤。.
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  • 文章类型: Journal Article
    失眠,作为情绪疾病之一,近年来一直在增加,这对人们的生活和工作有很大的影响。因此,研究人员渴望找到更完美的治疗方法。微生物组-肠-脑轴是近年来国外逐渐流行的一种新理论,在失眠领域产生了深远的影响。近年来,中医药在治疗失眠方面发挥着越来越重要的作用,尤其是针灸和中草药。是中医治疗失眠的主要方法。本文主要回顾了“微生物-肠-脑轴”理论与中医和针灸在中医系统下的结合程度。探讨"微生物-肠-脑轴"理论指导下中医及针灸治疗失眠的作用机制,以期为失眠的诊断和治疗提供新的思路。
    Insomnia, as one of the emotional diseases, has been increasing in recent years, which has a great impact on people\'s life and work. Therefore, researchers are eager to find a more perfect treatment. The microbiome-gut-brain axis is a new theory that has gradually become popular abroad in recent years and has a profound impact in the field of insomnia. In recent years, traditional Chinese medicine (TCM) has played an increasingly important role in the treatment of insomnia, especially acupuncture and Chinese herbal medicine. It is the main method of TCM in the treatment of insomnia. This paper mainly reviews the combination degree of \"microorganism-gut-brain axis\" theory with TCM and acupuncture under the system of TCM. To explore the mechanism of TCM and acupuncture in the treatment of insomnia under the guidance of \"microorganism-gut-brain axis\" theory, in order to provide a new idea for the diagnosis and treatment of insomnia.
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  • 文章类型: Journal Article
    The application of acupuncture and moxibustion in alleviating the adverse effects of chemotherapy drugs has been widely recognized at home and abroad, but the studies have been rarely summarized for the enhanced anti-tumor effect and its mechanism of acupuncture and moxibustion to synergize the chemotherapy drugs. This paper reviewed the clinical and basic studies on the synergism of chemotherapy with acupuncture and moxibustion in recent years. It was found that chemotherapy synergized with acupuncture and moxibustion can suppress cancer to a certain extent and improve the quality of life in patients. The effect mechanism of acupuncture and moxibustion combined with chemotherapy drugs is related to promoting tumor cell apoptosis, improving the immune and vascular microenvironment, and advancing chemotherapy drug enrichment on the affected area. It provides the evidences and ideas for enhancing the effect of chemotherapy by delivering acupuncture and moxibustion as an adjuvant therapy.
    针灸在减轻化疗药物不良反应方面的应用已经得到国内外的广泛认可,而对于其协同化疗增加抗肿瘤疗效的效应及其机制则较少进行归纳总结。本文对近几年针灸联合化疗增效的临床及基础研究进行回顾,结果显示针灸可一定程度协同化疗抑瘤,并改善患者生存质量;其效应机制与针灸联合化疗药物可促进肿瘤细胞凋亡、改善肿瘤免疫及血管微环境、促进肿瘤局部化疗药富集等有关。本文为针灸作为提高化疗疗效的辅助疗法提供证据和研究思路。.
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  • 文章类型: Journal Article
    OBJECTIVE: To observe the effect of acupuncture and moxibustion on arterial elasticity in patients with early carotid atherosclerosis.
    METHODS: A total of 62 patients with early carotid atherosclerosis were randomly divided into a blank group (12 cases, 1 cases dropped-off), a sham-acupuncture group (25 cases, 5 cases dropped-off) and an acupuncture group (25 cases, 3 cases dropped-off). Patients in the acupuncture group received acupuncture treatment, including ①acupuncture:Baihui (GV20), Yintang (GV24+), Renying (ST9), Neiguan (PC6), Yanglingquan (GB34);②moxibustion:Yinqiguiyuan (Zhongwan [CV12], Xiawan [CV10], Qihai [CV6], Guanyuan [CV4]), Sihua (Geshu [BL17], Danshu [BL19]);③Intradermal needle:Xinshu (BL15), Danshu (BL19). Patients in the sham acupuncture group received placebo acupuncture, moxibustion, an intradermal needle, and the acupoints were the same as the acupuncture group. The above treatments were performed twice a week for 12 weeks. No intervention was given to the patients in the blank group. Diet and lifestyle education was given to the three groups. The ultrafast pulse wave velocity, including beginning-systolic pulse wave velocity (BS) and end-systolic pulse wave velocity (ES), was observed before treatment and 1, 2, 3 months after treatment in the three groups. The blood lipid level and platelet count (PLT) at each time point were observed. The safety of the treatments was also evaluated.
    RESULTS: Compared with those before treatment, the BS and ES values of both sides in the acupuncture group decreased at 2 and 3 months after treatment (P<0.05). Compared with the blank group, the bilateral ES of the acupuncture group were decreased at 2 months after treatment (P<0.05), and the bilateral BS and ES were decreased at 3 months (P<0.05). Compared with the sham-acupuncture group, the acupuncture group showed a decrease in left BS and left ES after 3 months of treatment (P<0.05), and the overall decrease on the left side of the acupuncture group was better than that on the right side. There were no significant differences between three groups in the levels of blood lipid and PLT at each time point. No serious adverse safety events occurred in the three groups during the treatment.
    CONCLUSIONS: Acupuncture and moxibustion therapy can improve arterial elasticity in patients with early carotid atherosclerosis, and it is safe and effective.
    目的: 观察针灸对颈动脉粥样硬化早期患者动脉弹性的影响。方法: 将62例颈动脉粥样硬化早期患者随机分为空白组(12例,脱落1例)、假针灸组(25例,脱落5例)和针灸组(25例,脱落3例)。针灸组予针灸治疗,包括①针刺:百会、印堂、人迎、内关、阳陵泉;②精灸:引气归元(中脘、下脘、气海、关元)、四花(膈俞、胆俞);③皮内针:心俞、胆俞。假针灸组予安慰针刺、艾灸和皮内针治疗,穴位同针灸组。以上两组每周治疗2次,共治疗12周。空白组不进行干预。3组均予饮食及生活方式宣教。观察3组患者治疗前及治疗1、2、3个月后极速脉搏波速度,包括收缩初期脉搏波速度(BS)和收缩末期脉搏波速度(ES),以及各时点血脂水平和血小板计数(PLT),并进行安全性评价。结果: 与治疗前比较,针灸组治疗2个月和3个月后双侧BS值、ES值均下降(P<0.05);与空白组比较,针灸组治疗2个月后双侧ES均下降(P<0.05),治疗3个月后双侧BS与ES均下降(P<0.05);与假针灸组比较,针灸组治疗3个月后左侧BS与左侧ES均下降(P<0.05),针灸组左侧整体下降幅度优于右侧。各组患者治疗前后和组间血脂水平、PLT比较,差异均无统计学意义。治疗期间3组均无严重不良事件发生。结论: 针灸疗法具有改善颈动脉粥样硬化早期患者动脉弹性的作用,且安全有效。.
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  • 文章类型: English Abstract
    By extracting the acupoint names and their main indications from cases in Chinese Acupuncture and Moxibustion Therapy and Practical Acupuncture and Moxibustion, the acupoints and their main indications are represented in a reduced dimension, establishing an \"acupoint-indication\" linkage. Using complex network detection results (node degree values), the specificity of acupoints was assessed. The small-world characteristics of the \"acupoint-indication\" network are utilized to analyze the consistency of acupoint selection in acupuncture prescriptions and strategies to avoid redundant acupoints. The results show that the \"acupoint-indication\" network formed by both texts exhibited an approximate \"long-tail\" distribution, with a large number of node degree values concentrated between 0 and 4 000, while a few nodes have degree values exceeding 10 000. There are significant differences in the number and distribution of nodes with degree values> 10 000 between the two texts. Chinese Acupuncture and Moxibustion Therapy includes 11 acupoints with multiple edges across the body, whereas Practical Acupuncture and Moxibustion contains only 2 such acupoints, located in the lower limbs. Clinically, some acupoints have a broad therapeutic effect and appear in numerous prescriptions. The division of acupoints based on node degree values can coarsely evaluate the body region specificity of acupoints\' regulatory effects. The \"acupoint-indication\" network of Chinese Acupuncture and Moxibustion Therapy has a higher number of edges than that of Practical Acupuncture and Moxibustion, which might be related to the different historical contexts of the two texts. In the future, diagnostic and therapeutic patterns with historical continuity can be utilized to optimize acupuncture prescriptions.
    提取《中国针灸治疗学》《实用针灸学》中病案的腧穴名称、主治病症,对穴位与主治病症进行降维表示,建立“穴-症”联系,采用复杂网络检测结果(节点度值)评估穴位的特异性,利用穴-症网络的“小世界”特性分析针灸处方选穴的一致性和避免冗余穴位的策略。结果显示,两本著作形成的“穴-症”网络均存在近似“长尾”的度分布,大量节点度值集中在0~4 000,少量节点的度值高达10 000以上。对于度值>10 000的节点出现了明显的个数与分布差异,《中国针灸治疗学》中包括11个具有多连边数的穴位,遍布全身,《实用针灸学》中仅有2个多连边数的穴位,位于下肢。临床中存在个别穴位具有广泛的治疗效应,出现在大量处方中,通过节点度值的穴位划分能够粗粒度地评估穴位调控作用的躯体区域特异性;《中国针灸治疗学》穴-症网络连边数高于《实用针灸学》穴-症网络,与2本著作不同的时代背景有关,今后可利用具有时代传承特征的诊疗规律优化针灸处方。.
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  • 文章类型: Journal Article
    OBJECTIVE: To explore the rules of acupoint selection and pattern-acupoint relationship in treatment with acupuncture and moxibustion for endometriosis (EMs) based on complex network analysis technology.
    METHODS: The articles for clinical trial of EMs treated with acupuncture and moxibustion were searched from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase and Cochrane Library from the inception of the databases to December 14, 2022. Using Microsoft Excel 2019 software, the database was established to collect the use frequency of acupoint, meridian tropism, location and pattern-acupoint relationship. SPSS Modeler 18.0 Apriori algorithm was adopted to conduct the association rule analysis, Cytoscape3.7.2 software was used to plot the complex co-occurrence network map; and SPSS Statistics 26.0 was adopted to perform hierarchical cluster analysis on high-frequency acupoints and a tree diagram was drawn.
    RESULTS: A total of 163 articles were included, and 167 core acupoint prescriptions and 74 pattern-associated acupoint prescriptions were extracted, involving 92 acupoints, with a cumulative frequency of 1 223 times. The top five acupoints with the highest use frequency were Guanyuan (CV 4), Sanyinjiao (SP 6), Zhongji (CV 3), Zigong (EX-CA 1) and Qihai (CV 6). The selected acupoints were mostly distributed in the chest, abdomen and lower limbs; and the involved meridians included the conception vessel, the spleen meridian of foot-taiyin and the stomach meridian of foot-yangming. The acupoint compatibility of high frequency referred to Guanyuan (CV 4) - Sanyinjiao (SP 6), Guanyuan (CV 4) - Zhongji (CV 3), and Guanyuan (CV 4) - Zigong (EX-CA 1). The close association was presented among Guanyuan (CV 4), Sanyinjiao (SP 6), Qihai (CV 6) and Zhongji (CV 3), which had the strongest connection with the other acupoints; among the top 25 acupoints with the highest use frequency, 5 acupoint prescriptions with high frequency were obtained by the cluster analysis. Guanyuan (CV 4), Qihai (CV 6), Sanyinjiao (SP 6), Zigong (EX-CA 1) and Zhongji (CV 3) were selected for cold and blood stagnation; Guanyuan (CV 4), Sanyinjiao (SP 6), Zhongji (CV 3), Dahe (KI 12) and Taixi (KI 3) for kidney deficiency and blood stagnation; Zhongji (CV 3), Guanyuan (CV 4), Sanyinjiao (SP 6), Xuehai (SP 10) and Diji (SP 8) for qi and blood stagnation; Qihai (CV 6), Guanyuan (CV 4), Zusanli (ST 36), Xuehai (SP 10), and Zigong (EX-CA 1) for qi deficiency and blood stagnation; Sanyinjiao (SP 6), Fenglong (ST 40), Zhongliao (BL 33), Ciliao (BL 32) and Xialiao (BL 34) for interaction of phlegm and stasis; and Daheng (SP 15), Guanyuan (CV 4), Zhongji (CV 3), Qihai (CV 6) and Zhongwan (CV 12) for retention of damp and heat.
    CONCLUSIONS: The core acupoints are Guanyuan (CV 4), Sanyinjiao (SP 6), Zhongji (CV 3), Qihai (CV 6) and Zigong (EX-CA 1) in treatment of endometriosis with acupuncture and moxibustion. Six patterns/syndromes are involved in clinical practice. In terms of the properties, functions and indications, the supplementary acupoints are selected on the basis of the core acupoints for different patterns/sydnromes of the disease.
    目的:基于复杂网络分析技术探索针灸治疗子宫内膜异位症(EMs)的选穴规律与证-穴关系。方法:检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普中文科技期刊数据库(VIP)、中国生物医学文献数据库(SinoMed)、PubMed、EMbase、Cochrane Library建库至2022年12月14日收录的针灸治疗EMs的临床研究文献。采用Microsoft Excel 2019软件建立数据库,统计腧穴频次及频率、腧穴归经、腧穴分布、证-穴关系,并使用SPSS Modeler 18.0软件中的Apriori算法进行关联规则分析;采用Cytoscape3.7.2软件绘制复杂共现网络图谱;运用SPSS Statistics 26.0软件对高频腧穴实现层次聚类分析并绘制树状图。结果:共纳入163篇文献,提取核心处方167条,证型-腧穴处方74条,涉及腧穴92个,累计频次1 223次。使用频次前5的腧穴为关元、三阴交、中极、气海、子宫;腧穴归经以任脉、足太阴脾经与足阳明胃经为主,胸腹部与下肢部腧穴占比较高;关元-三阴交、关元-中极、关元-子宫为高频腧穴配伍;关元、三阴交、气海、中极相互之间联系紧密,与其他穴位的联通性最好;前25位高频腧穴可分为5个有效聚类群。寒凝血瘀证常用穴位为关元、气海、三阴交、子宫、中极;肾虚血瘀证常用穴位为关元、三阴交、中极、大赫、太溪;气滞血瘀证常用穴位为中极、关元、三阴交、血海、地机;气虚血瘀证常用穴位为气海、关元、足三里、血海、子宫;痰瘀互结证常用穴位为三阴交、丰隆、中髎、次髎、下髎;湿热瘀阻证常用穴位为大横、关元、中极、气海、中脘。结论:针灸治疗EMs核心处方为关元、三阴交、中极、气海、子宫,临床以6类证型为主,当根据不同证型在核心处方基础上配以对证穴位。.
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  • 文章类型: Journal Article
    There are the differences in the location of some acupoints between textbooks Meridians and Acupoints and Acupuncture and Moxibustion. Both of the textbooks are in the category of the \"14th Five-Year Plan\". The differences in acupoint location have brought some confusion for students, full-time teachers and researchers in the field of traditional Chinese medicine. In the paper, based on GB/T 12346-2021: Nomenclature and Location of Meridian Points, published in2021, and in reference with GB/T 12346-2006: Nomenclature and Location of Acupuncture Points, published in 2006, the discrepancy in the acupoint location was systematically collated in the aspects of the expression style and layout, text expression and potential difference of location between these two textbooks, published by China Press of Traditional Chinese Medicine, People\'s Medical Publishing House and China Science Publishing. Based on the historical evolution and the academic controversy of acupoint positioning, the reasons of the differences in acupoint location were analyzed, the potential influences on the teaching, examination, competition and research of Chinese medicine acupuncture were explored, and the suggestions for solution were proposed.
    《经络腧穴学》和《针灸学》“十四五”规划教材中部分经穴定位存在差异,这给中医学类学生、专任教师和科研工作者带来了一定的困惑。本文以2021年中华人民共和国国家标准《经穴名称与定位(GB/T 12346—2021)》为依据,参照2006年国家标准《腧穴名称与定位(GB/T 12346—2006)》,从经穴定位表述体例的差异、经穴定位文字表述的差异、经穴定位位置潜在的差异等方面分别系统梳理出了中国中医药出版社、人民卫生出版社和科学出版社出版的《经络腧穴学》与《针灸学》“十四五”规划教材的经穴定位差异。并且进一步从腧穴定位的历史演变和腧穴定位的学术争议分析了不同教材经穴定位差异的原因,探讨了教材经穴定位差异对中医针灸教学、考试、比赛、临床、科研的潜在影响,并尝试提出了建议解决方法。.
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