周围神经损伤的常见后遗症是异常再生和恢复。受损运动神经的异常再生可以影响从运动皮质到目标肌肉的神经回路的各个方面。异常运动神经肌肉神经支配后出现的症状的更全面术语是异常神经支配综合征(ARS)。面神经损伤后的异常神经支配导致一系列症状,这在文献中被称为许多事情。作者支持这种常见的面神经损伤后遗症称为面部异常神经支配综合征(FARS)。一个更能描述潜在病理生理学和更包括临床症状的术语:面部联合运动,面部肌肉过度紧张,面部肌肉痉挛/抽搐,发生在面神经损伤和恢复后。在下面的文章中,我们介绍了面神经损伤和恢复的临床表现和后遗症,并简要讨论了我们对FARS的病理生理和治疗的认识。
A common sequela of peripheral nerve injury is aberrant regeneration and recovery. Aberrant regeneration of injured motor nerves can affect all aspects of the nerve circuit from the motor cortex to the target muscle. A more comprehensive term for the symptoms that develop after aberrant motor neuromuscular reinnervation is aberrant reinnervation syndrome (ARS). Injury to the facial nerve followed by aberrant reinnervation results in a spectrum of symptoms that has been called many things in the literature. The authors support that this commonly encountered sequela of facial nerve injury be called facial aberrant reinnervation syndrome (FARS), a term that is more descriptive of the underlying pathophysiology and more inclusive of the clinical symptoms: facial synkinesis, facial muscle hypertonicity, and facial muscle spasm/twitching, which occur following facial nerve injury and recovery. In the following article, we present the clinical manifestations and sequelae of facial nerve injury and recovery and briefly discuss our evolving understanding of the pathophysiology and treatment of FARS.