疼痛素数的管理已被证明会影响对连续呈现的语义刺激的感知。疼痛的素数导致疼痛相关的负价评级,负,积极的话语比没有素数。与疼痛相关的单词比负面单词的效果更大。这种效应的神经相关性的身份仍然未知。在这个脑电图实验中,48名健康受试者接受中等强度的有害电刺激。在这个启动过程中,他们被呈现为可变效价的形容词(疼痛相关,负,积极的,和中立)。在N1(120-180ms)期间分析触发的事件相关电位,P2(170-260ms),P3(300-350ms),N400(370-550ms),和两个晚期正复分量(LPC1[650-750ms]和LPC2[750-1000ms])。与后期成分(N400,LPC1和LPC2)中的阳性单词相比,阴性和疼痛相关单词的事件相关电位更大。主要在额叶区域。早期成分(N1,P2)受单词类别的影响较小,但受主要条件的影响(N1振幅小于没有疼痛刺激的情况,P2振幅大于无疼痛刺激)。后来的组件(LPC1,LPC2)不受主要条件的影响。在行为水平而不是电生理水平上发现了涉及主要和单词类别的交互效应。这一发现表明,相互作用效应不会直接从行为水平转化为电生理水平。讨论了这种差异的可能原因。
The administration of painful primes has been shown to influence the perception of successively presented semantic stimuli. Painful primes lead to more negative valence ratings of pain-related, negative, and positive words than no prime. This effect was greater for pain-related than negative words. The identities of this effect\'s neural correlates remain unknown. In this EEG experiment, 48 healthy subjects received noxious electrical stimuli of moderate intensity. During this priming, they were presented with adjectives of variable valence (pain-related, negative, positive, and neutral). The triggered event-related potentials were analyzed during N1 (120-180 ms), P2 (170-260 ms), P3 (300-350 ms), N400 (370-550 ms), and two late positive complex components (LPC1 [650-750 ms] and LPC2 [750-1000 ms]). Larger event-related potentials were found for negative and pain-related words compared to positive words in later components (N400, LPC1, and LPC2), mainly in the frontal regions. Early components (N1, P2) were less affected by the word category but were by the prime condition (N1 amplitude was smaller with than without painful stimulation, P2 amplitude was larger with than without painful stimulation). Later components (LPC1, LPC2) were not affected by the prime condition. An interaction effect involving prime and word category was found on the behavioral level but not the electrophysiological level. This finding indicates that the interaction effect does not directly translate from the behavioral to the electrophysiological level. Possible reasons for this discrepancy are discussed.