Women’s Health

妇女健康
  • 文章类型: Journal Article
    本研究旨在研究配偶支持对不同依恋方式的女性产后抑郁症的影响,并评估依恋方式是否会影响这种影响。
    2022年3月至5月,在山东省和广东省三级妇产医院随机抽取96对晚期孕妇夫妇进行产前调查。使用成人依恋量表进行心理评估,二元应对库存,和患者健康问卷-9(PHQ-9)抑郁量表。为了检查每个变量与产后抑郁之间的关系,采用单因素和多因素logistic回归分析.此外,互动分析用于分析不同依恋方式之间的相互作用以及配偶支持对女性产后抑郁的影响。
    研究结果表明,即使考虑了混杂变量,产前配偶支持是产后抑郁的独立预测因子(校正比值比(OR)=0.82,95%CI:0.69-0.96,P=0.015)。具有安全依恋风格的女性与具有不安全依恋风格的女性相比,产后抑郁症的发生率显着降低(24.2%vs.46%,P=.037)。在安全附件组中,配偶支持对产后抑郁症有保护作用(校正OR=0.57,95%CI:0.36-0.91,P=.018),和依恋方式成为影响配偶支持对产后抑郁影响的潜在交互因素(P=0.029)。
    提供配偶支持,特别是对于具有安全依恋风格的个人,对产后抑郁症有预防作用。这强调了在针对产后抑郁症预防的干预措施中考虑依恋风格的重要性。
    UNASSIGNED: This study aims to examine the impact of spousal support on postpartum depression in women with different attachment styles and assessing if attachment style influences this effect.
    UNASSIGNED: From March to May 2022, 96 couples with late-stage pregnant women were randomly selected from tertiary maternity hospitals in Shandong and Guangdong provinces for a prepartum survey. Psychological assessments were conducted using the Adult Attachment Scale, Dyadic Coping Inventory, and the Patient Health Questionnaire-9 (PHQ-9) Depression Scale. To examine the relationship between each variable and postpartum depression, univariate and multiple logistic regression analyses were employed. Additionally, interaction analysis was used to analyze the interplay between different attachment styles and how spousal support influences women\'s postpartum depression.
    UNASSIGNED: The findings revealed that even after accounting for confounding variables, prepartum spousal support was an independent predictor of postpartum depression (adjusted odds ratio (OR) = 0.82, 95% CI: 0.69-0.96, P = .015). Women with a secure attachment style showed a significantly lower incidence of postpartum depression compared to those with insecure attachment styles (24.2% vs. 46%, P = .037). In the secure attachment group, spousal support had a protective effect against postpartum depression (adjusted OR = 0.57, 95% CI: 0.36-0.91, P = .018), and attachment style emerged as a potential interactive factor influencing the impact of spousal support on postpartum depression (P for interaction = .029).
    UNASSIGNED: The provision of spousal support, especially to individuals with secure attachment styles, plays a preventive role in postpartum depression. This underscores the importance of considering attachment styles in interventions targeting postpartum depression prevention.
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  • 文章类型: Journal Article
    公共卫生问题应该成为公共领导人关注的焦点。阐明预期政策的关键时刻是在选举期间。此时,候选人提出了从对上届政府治理的评估和反思中得出的重要想法和建议。这种方法确保拟议的方案有证据。2024年,印尼举行大选,在严重的公共卫生挑战中,例如发育迟缓的患病率持续很高,母婴健康状况不佳。Prabowo-Gibran,谁赢得了选举,他们的运动重点是提供免费食物和牛奶。这项运动似乎没有全面的改进计划的支持,导致人们的印象是公共卫生问题只是用来增强选举吸引力。
    Public health issues should be a focal concern for public leaders. A critical moment for articulating intended policies is during elections. At this time, candidates present significant ideas and proposals derived from the evaluation and reflection on the previous administration\'s governance. This approach ensures that the proposed programmes are grounded in evidence. In 2024, Indonesia conducted general elections, amid significant public health challenges such as the persistently high prevalence of stunting and poor maternal and child health outcomes. The Prabowo-Gibran, who then won the election, focused their campaign on providing free food and milk. This campaign appears to be unsupported by a comprehensive improvement plan, leading to the impression that public health issues are merely used to enhance electoral appeal.
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  • 文章类型: Journal Article
    目的:评估非药物治疗的有效性,保守治疗女性慢性盆腔疼痛(CPP)。
    方法:对电子数据库的系统搜索(Amed,CINAHL,PsycINFO,运动讨论,Medline,PubMed,Embase,和Cochrane中央受控试验登记册)于2023年1月进行,并于2023年12月进行了更新。
    方法:随机对照试验(RCT)比较非药物,对惰性的保守治疗(例如,安慰剂,常规护理)或非保守(例如,外科,药物)治疗包括在内。本综述感兴趣的保守治疗是:多模式物理治疗,主要是心理方法,针灸,和其他基于组织的单一疗法(例如,电物理试剂,手动拉伸)。
    方法:所有研究数据都是汇总的,并对纳入的研究进行分析.对疼痛的影响;性措施;心理和身体功能;健康相关的生活质量;症状严重程度/困扰;盆底肌肉功能和形态计量学;感知改善;和不良事件进行分析。使用干预后评分对包括类似干预措施和结果的数据进行荟萃分析(随机效应模型)。计算标准化平均差(SMD)。提供了无法包含在荟萃分析中的结果的叙述性总结。用PEDro量表评估证据的质量,用建议分级评估证据的确定性,评估,发展,和评估(等级)标准。
    结果:在检索到的5776项研究中,纳入38项RCTs,包括2168名女性(平均年龄35.1±8.6)。荟萃分析显示,在短期(SMD-1.69,95%CI-2.54,-0.85;高确定性)和中期(SMD-1.82,95%CI-3.13,-0.52;中等确定性),与惰性或非保守治疗相比,多模式物理治疗导致疼痛强度降低。而主要的心理方法导致疼痛强度无差异(SMD-0.18,95%CI-0.56,0.20;中度确定性),性功能略有差异(SMD-0.28,95%CI-0.52,-0.04;中度确定性).关于针灸对疼痛强度影响的荟萃分析的证据水平(SMD1.08,95%CI-1.38,3.54,支持对照治疗的无统计学意义的结果)排除了任何确定性陈述。有限数量的试验调查了个体基于组织的单一疗法,提供有限的证据。
    结论:这项系统综述的荟萃分析显示,多模式物理治疗对CPP女性有效,证据具有很高的确定性。
    OBJECTIVE: To evaluate the effectiveness of non-pharmacological, conservative therapies for women with chronic pelvic pain (CPP).
    METHODS: A systematic search of electronic databases (Amed, CINAHL, PsycINFO, SportDiscuss, Medline, PubMed, Embase, and Cochrane Central Register of Controlled Trials) was performed in January 2023, and updated in December 2023.
    METHODS: Randomized controlled trials (RCTs) comparing a non-pharmacological, conservative therapy to inert (e.g., placebo, usual care) or non-conservative (e.g., surgical, pharmacological) treatment were included. Conservative therapies of interest to this review were: multimodal physical therapy, predominantly psychological approaches, acupuncture, and other tissue-based monotherapies (e.g., electrophysical agents, manual stretching).
    METHODS: All study data were aggregated, and analyses of the included studies were performed. Effects on pain; sexual measures; psychological and physical function; health-related quality of life; symptom severity/bother; pelvic floor muscle function and morphometry; perceived improvement; and adverse events were analyzed. Meta-analyses (random effects model) were conducted using post-intervention scores for data that included similar interventions and outcomes. Standardized mean differences (SMD) were calculated. A narrative summary of findings that could not be included in the meta-analysis is provided. The quality of the evidence was assessed with the PEDro scale and the certainty of evidence with Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) criteria.
    RESULTS: Of 5776 retrieved studies, 38 RCTs including 2168 women (mean age 35.1±8.6) were included. Meta-analyses revealed that multimodal physical therapy resulted in lower pain intensity compared to inert or non-conservative treatments in both the short (SMD -1.69, 95% CI -2.54,-0.85; high certainty) and intermediate-terms (SMD -1.82, 95% CI -3.13, -0.52; moderate certainty), while predominantly psychological approaches resulted in no difference in pain intensity (SMD -0.18, 95% CI -0.56, 0.20; moderate certainty) and a slight difference in sexual function (SMD -0.28, 95% CI -0.52,-0.04; moderate certainty). The level of evidence regarding the meta-analysis of the effects of acupuncture on pain intensity (SMD 1.08, 95% CI -1.38, 3.54, non-statistically significant results in favor of control treatment) precluded any statement of certainty. A limited number of trials investigated individual tissue-based monotherapies, providing a restricted body of evidence.
    CONCLUSIONS: This systematic review with meta-analysis revealed that multimodal physical therapy is effective in women with CPP with a high certainty of evidence.
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  • 文章类型: Journal Article
    背景:数字技术和游戏化应用程序在医疗保健环境中很有用。游戏化使用技术通过类似游戏的体验来影响用户的行为和动机。患者坚持增强术后恢复(ERAS)计划对于实现术后早期恢复至关重要,并且持续监测对于获得良好结果至关重要。
    目的:本研究旨在描述用于增强术后恢复的移动应用程序(MobERAS)的开发和验证,一个游戏化的移动健康应用程序,用于根据ERAS计划在术后期间对患者进行远程监护,并评估其功能和可用性以及患者的体验,卫生保健专业人员,和计算机专业人员使用它。
    方法:我们开发了用于术后远程监测的MobERAS,在患者积极参与的过程中,并为卫生团队提供实时信息。应用程序开发过程包括理想化,跨学科团队组建,潜在需求评估,和产品部署。在整个开发过程中进行了可用性测试,并进行了改进,技术调整,和更新。定稿后,进行了全面的验证试验。评估的参数是那些可以影响住院时间的参数,比如恶心,呕吐,疼痛量表,恢复正常的胃肠功能,和血栓栓塞事件。MobERAS旨在由用户在手机上下载,片剂,或其他移动设备,并提供术后数据。该应用程序有一个GPS,监测患者的步行时间和距离,并连接到存储收集的数据的虚拟数据库。
    结果:纳入接受中型和大型妇科肿瘤手术的妇女。我们纳入了65例患者,平均年龄为53.2岁(SD7.4,范围18-85岁)。使用时间为23.4至70小时(平均45.1,SD19.2小时)。关于坚持使用MobERAS,平均填充率为56.3%(标准差为12.1%,范围41.7%-100%),并获得了65例患者中60例(92.3%)的下床数据。研究人员可以实时访问患者填写的数据。患者很好地接受了MobERAS的使用,与应用程序的可用性的良好评价。MobERAS易于使用,并且由于其游戏化的设计而被认为具有吸引力。该应用程序在所有项目中被医疗保健专业人员(n=20)和专门从事技术创新的专业人员(n=10)评为好或非常好。
    结论:MobERAS易于使用,安全,被患者接受,并得到专家的良好评估。它可以在临床外科实践中非常有用,并且是使患者和医疗保健专业人员更多参与ERAS计划的重要工具。
    BACKGROUND: Digital technology and gamified apps can be useful in the health care context. Gamification uses technology to influence users\' actions and motivations through experiences that resemble games. Patient adherence to the enhanced recovery after surgery (ERAS) program is crucial for achieving early recovery after surgery and continuous monitoring is essential for obtaining good results.
    OBJECTIVE: This study aimed to describe the development and validation of a mobile app for enhanced recovery after surgery (MobERAS), a gamified mobile health app for telemonitoring patients in the postoperative period based on the ERAS program, and to evaluate its functionality and usability and the experience of patients, health care professionals, and computer professionals with its use.
    METHODS: We developed MobERAS for postoperative telemonitoring, with active participation of patients in the process, and offering availability of real-time information for the health team. The app development process included idealization, interdisciplinary team formation, potential needs assessment, and product deployment. Usability tests were conducted throughout the development process with improvements, technical adjustments, and updates. After finalization, comprehensive verification tests were performed. The parameters evaluated are those that can influence the length of hospital stay, such as nausea, vomiting, pain scales, return to normal gastrointestinal function, and thromboembolic events. MobERAS was designed to be downloaded by users on their phones, tablets, or other mobile devices and to provide postoperative data. The app has a GPS that monitors the patient\'s walking time and distance and is connected to a virtual database that stores the collected data.
    RESULTS: Women undergoing medium and major gynecologic oncologic surgeries were included. We included 65 patients with an average age of 53.2 (SD 7.4, range 18-85) years. The time of use ranged from 23.4 to 70 hours (mean 45.1, SD 19.2 hours). Regarding adherence to the use of MobERAS, the mean fill rate was 56.3% (SD 12.1%, range 41.7%-100%), and ambulation data were obtained for 60 (92.3%) of the 65 patients. The researcher had access to the data filled out by the patients in real time. There was good acceptance of the use of MobERAS by the patients, with good evaluation of the app\'s usability. MobERAS was easy to use and considered attractive because of its gamified design. The app was rated as good or very good in all items by health care professionals (n=20) and professionals specializing in technological innovation (n=10).
    CONCLUSIONS: MobERAS is easy to use, safe, well accepted by patients, and well evaluated by experts. It can be of great use in clinical surgical practice and an important tool for greater engagement of patients and health care professionals with the ERAS program.
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  • 文章类型: Journal Article
    性受害(SV)在大学女性中很常见,大约一半经历过SV的人在一年内符合创伤后应激障碍(PTSD)的标准。SV和PTSD都与大学女性的酒精滥用有关,通常用自我药疗假说来解释。现有文献关注的是PTSD的整体严重程度,而不是特定症状的潜在日常波动,这可能在理解酒精滥用风险中起着至关重要的作用。研究还只检查了创伤后应激障碍和饮酒之间的同一天或第二天的关联,忽视了长期变化的潜力。
    本研究探讨了PTSD症状的短期纵向稳定性和时滞预测动态,影响,和饮酒行为的174名女性大学重度饮酒者超过四个星期。参与者分为三组:有SV和PTSD病史的人(n=77),患有SV但没有PTSD的女性(n=59),和没有创伤史的女性(n=38)能够通过创伤暴露来检查差异,PTSD我们比较了PTSD症状网络的纵向稳定性,影响(唤醒,积极的影响,和负面影响),以及跨群体的饮酒行为。支持向量回归确定哪些PTSD症状网络和影响最好地预测在0-7天范围内的特定时间滞后的饮酒行为。
    PTSD组对PTSD症状网络(调整后的ps<.049)和唤醒(调整后的ps<.048)显示出更高的纵向稳定性,但负面影响(调整后的p=0.013)和饮酒行为的稳定性较低,包括对酒精的渴望(调整后的p=.019)和消费量(调整后的p=.012),与对照组相比。这表明PTSD患者的症状和唤醒水平更稳定,但负面影响和酒精相关行为的波动更大。二次分析显示,PTSD症状网络可以最佳地预测酒精渴望的三天时间滞后(r=.88,p<.001)和消费的四天时间滞后(r=.82,p<.001)。
    这些发现挑战了关于创伤后应激障碍的直接影响和对饮酒行为的影响的假设,并强调了需要考虑长期影响的治疗方法。未来的研究应该通过纳入更长期的评估和探索更广泛的症状相互作用来扩展这些发现。
    UNASSIGNED: Sexual victimization (SV) is common among college women, with approximately half of those who have experienced SV meeting criteria for posttraumatic stress disorder (PTSD) within a year. Both SV and PTSD are associated with alcohol misuse among college women, often explained by the self-medication hypothesis. Existing literature focuses on overall PTSD severity rather than potential day-to-day fluctuations in specific symptoms, which might play a crucial role in understanding alcohol misuse risk. Studies also examine only same-day or next-day associations between PTSD and drinking, neglecting the potential for longer-term changes.
    UNASSIGNED: This study explores the short-term longitudinal stability and time-lagged predictive dynamics of PTSD symptoms, affect, and drinking behavior among 174 female college heavy episodic drinkers over four weeks. Participants were categorized into three groups: those with a history of SV and PTSD (n = 77), women with SV but without PTSD (n = 59), and women without prior trauma history (n = 38) to be able to examine differences by trauma exposure, and PTSD. We compared the longitudinal stability of PTSD symptom networks, affect (arousal, positive affect, and negative affect), and drinking behavior across groups. Support vector regression determined which PTSD symptom networks and affect best predict drinking behavior at specific time lags within a 0-7 day range.
    UNASSIGNED: The PTSD group showed higher longitudinal stability for PTSD symptom networks (adjusted ps <.049) and arousal (adjusted ps <.048), but lower stability for negative affect (adjusted p =.013) and drinking behavior, including alcohol cravings (adjusted p =.019) and consumption (adjusted ps =.012), compared to the comparison groups. This suggests individuals with PTSD have more stable symptoms and arousal levels but greater fluctuations in negative affect and alcohol-related behaviors. Secondary analysis revealed PTSD symptom networks optimally predicted alcohol cravings with a three-day time lag (r=.88, p <.001) and consumption with a four-day time lag (r=.82, p <.001).
    UNASSIGNED: These findings challenge assumptions regarding immediate effects of PTSD and affect on drinking behavior and underscore the need for therapeutic approaches that consider longer-range effects. Future research should expand on these findings by incorporating longer-range assessments and exploring a broader range of symptom interactions.
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  • 文章类型: Journal Article
    背景:研究表明,粮食不安全与压力之间存在双向关系,但是很少有研究研究食物不安全与压力和其他心脏代谢健康指标的关系,包括抑郁症,饮食质量,和体重,在美国低收入女性中
    方法:这项横断面研究分析了居住在北卡罗来纳州(n=100)的低收入女性照顾者的数据:42%的黑人/非洲裔美国人,25%西班牙裔/拉丁裔,33%的白人女性。多变量线性回归模型用于确定食品不安全状态与感知压力的关联,抑郁症状,饮食质量,体重指数(BMI)。使用多变量逻辑回归模型来确定食品不安全与临床抑郁症和BMI≥30kg/m2的相关性。在有和没有调整感知压力的情况下检查关联。
    结果:42%的样本经历了粮食不安全。与食品安全护理人员相比,食物不安全的护理人员的感知压力(β:+7.51;95CI:4.19,10.84)和抑郁症状(β:+3.55;95CI:0.54,6.56)显著较高,且饮食质量较低(β:-9.10;95CI:-15.81,-2.40).与BMI结果的关联没有统计学意义。
    结论:研究结果支持在营养援助计划和临床相互作用中消除污名,激励未来的纵向研究,并为促进健康或预防疾病的消除污名化干预措施的发展提供信息。
    BACKGROUND: Research suggests a bidirectional relationship between food insecurity and stress, but few studies have examined associations of food insecurity with stress and other indicators of cardiometabolic health, including depression, diet quality, and body weight, among lower-income women in the U.S.
    METHODS: This cross-sectional study analyzed data from lower-income women caregivers living in North Carolina (n = 100): 42% Black/African American, 25% Hispanic/Latina, and 33% White women. Multivariable linear regression models were used to determine associations of food insecurity status with perceived stress, depressive symptoms, diet quality, and body mass index (BMI). Multivariable logistic regression models were used to determine associations of food insecurity with clinical depression and BMI ≥ 30 kg/m2. Associations were examined with and without adjustment for perceived stress.
    RESULTS: Forty-two percent of the sample were experiencing food insecurity. Compared to food secure caregivers, food-insecure caregivers had significantly higher perceived stress (β: +7.51; 95%CI: 4.19, 10.84) and depressive symptoms (β: +3.55; 95%CI: 0.54, 6.56) and lower diet quality (β: -9.10; 95%CI: -15.81, -2.40). Associations with BMI outcomes were not statistically significant.
    CONCLUSIONS: Findings support removing stigma in nutrition assistance programs and clinical interactions, motivate future longitudinal studies, and inform the development of destigmatizing interventions for health promotion or disease prevention.
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  • 文章类型: Journal Article
    在过去的几十年中,大量索马里妇女在全球各地迁移。对于东道国的医护人员来说,了解索马里妇女的医疗保健需求至关重要。大多数索马里女性移民经历女性生殖器切割(FGC)。索马里最常见的类型是3型或阴锁,阴道口变窄.下阴锁假手术可打开入口,以减少不良的健康结果和/或允许阴道分娩。在这项研究中,我们探讨了居住在美国的索马里妇女对去阴锁的看法。我们通过基于社区的参与研究方法招募了75名经历过FGC的索马里妇女。双语社区研究人员用索马里语或英语进行了定性访谈。大学教师和社区研究人员在参与式分析过程中将数据编码在一起。我们确定了四个主题。(1)个人观点:参与者报告了对去阴锁的积极态度,并且在婚前去阴锁的适当性方面有所不同。(2)好处:确定的好处包括减轻健康问题;改善性健康,特别是减少或预防性疼痛;以及恢复身体和女性。(3)障碍:这些障碍包括相关的耻辱和提供者缺乏知识。(4)决策:大多数报告说,丈夫,医疗保健提供者,年长的女性社区成员可以提供有关是否和/或何时寻求去阴部的建议,尽管有些人认为去阴部的决定完全取决于受影响的女性。生态框架用于构建调查结果,并确定医护人员在协助被告知的妇女做出决定方面的重要性。
    The past decades have seen large numbers of Somali women migrate across the globe. It is critical for healthcare workers in host countries to understand healthcare needs of Somali women. The majority of Somali female migrants experience female genital cutting (FGC). The most common type in Somalia is Type 3 or infibulation, the narrowing of the vaginal introitus. Deinfibulation opens the introitus to reduce poor health outcomes and/or allow for vaginal births. In this study, we explored the perspectives of Somali women living in the United States about deinfibulation. We recruited 75 Somali women who had experienced FGC through community-based participatory research methods. Bilingual community researchers conducted qualitative interviews in Somali or English. University faculty and community-based researchers coded data together in a participatory-analysis process. We identified four themes. (1) Personal Views: participants reported positive attitudes toward deinfibulation and varied on the appropriateness of deinfibulation before marriage. (2) Benefits: identified benefits included alleviation of health problems; improved sexual health, in particular reduction or prevention of sexual pain; and reclamation of body and womanhood. (3) Barriers: these included associated stigma and lack of knowledge by providers. (4) Decision-Making: most reported that husbands, healthcare providers, and elder female community members may provide advice about if and/or when to seek deinfibulation, though some felt deinfibulation decisions are solely up to the impacted woman. An ecological framework is used to frame the findings and identify the importance of healthcare workers in assisting women who have been infibulated make decisions.
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  • 文章类型: Journal Article
    性传播感染(STIs)在全球范围内引起相当大的发病率,根据特定的病原体,可能导致女性生殖道严重并发症。被监禁的妇女特别容易受到健康问题的影响,性传播感染的比例过高,包括人乳头瘤病毒(HPV)感染。
    这里,从生活在圣保罗女子监狱之一的299名妇女(18至64岁)收集的宫颈拭子样本,巴西提交了液基细胞学检查,以确定癌前病变的患病率。此外,直接检测30个生殖器HPV基因型(18个高危型和12个低危型)和11个额外的性传播感染(沙眼衣原体,淋病奈瑟菌,单纯疱疹病毒1型和2型,猪嗜血杆菌,生殖支原体和人源支原体,梅毒螺旋体,阴道毛滴虫,细小脲原体和解脲脲原体)通过使用两个基于PCR的DNA微阵列系统进行分子分型,即,EUROArrayHPV和EUROArraySTI(EUROIMMUN),分别。
    细胞学异常的总体患病率为5.8%,包括5例低级别女性和5例高级别鳞状上皮内病变女性。HPV的总体患病率为62.2,并且87.1%的HPV阳性女性感染了致癌高风险(HR)HPV类型。HPV类型16(24.1%),33和52(均为10.4%)的检测频率最高。其他性传播感染的患病率为72.8%。在受感染的妇女中发现了多达四种不同的病原体,最常见的是细小脲原体(45.3%),人型支原体(36.2%)和阴道毛滴虫(24.8%)。
    这里描述的HR-HPV感染和其他性传播感染的高数量突出了巴西女性监狱人口在国家卫生政策中需要更多关注的事实。筛查计划和治疗措施的实施可能有助于减少这一脆弱人群中性传播感染和宫颈癌的发病率。然而,为了使这些措施有效,需要进一步研究以调查最佳做法,以使更多妇女参与监狱预防计划,例如,通过提供进一步的性健康教育和自我抽样。
    UNASSIGNED: Sexually transmitted infections (STIs) cause considerable morbidity worldwide and, depending on the specific pathogen, may lead to serious complications in the female reproductive tract. Incarcerated women are particularly vulnerable to health problems with a disproportionate high rate of STIs, including infections with human papillomavirus (HPV).
    UNASSIGNED: Here, cervical swab samples collected from 299 women (18 to 64 years) living in one of the women\'s prisons of São Paulo, Brazil were submitted for liquid-based cytology to determine the prevalence of precancerous lesions. Furthermore, direct detection of 30 genital HPV genotypes (18 high-risk and 12 low-risk types) and 11 additional STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex virus 1 and 2, Haemophilus ducreyi, Mycoplasma genitalium and hominis, Treponema pallidum, Trichomonas vaginalis, Ureaplasma parvum and urealyticum) were performed by molecular typing using two PCR-based DNA microarray systems, i.e., EUROArray HPV and EUROArray STI (EUROIMMUN), respectively.
    UNASSIGNED: The overall prevalence of cytological abnormalities was 5.8%, including five women with low-grade and five women with high-grade squamous intraepithelial lesions. The overall prevalence of HPV was 62.2, and 87.1% of the HPV-positive women were infected with oncogenic high-risk (HR) HPV types. HPV types 16 (24.1%), 33 and 52 (both 10.4%) were the most frequently detected. The prevalence of the other STIs was 72.8%. Up to four different pathogens were found in the infected women, the most frequent being Ureaplasma parvum (45.3%), Mycoplasma hominis (36.2%) and Trichomonas vaginalis (24.8%).
    UNASSIGNED: The high number of HR-HPV infections and other STIs described here highlights the fact that the Brazilian female prison population requires more attention in the country\'s health policies. The implementation of screening programs and treatment measures might contribute to a decrease in the incidence of STIs and cervical cancer in this vulnerable population. However, for such measures to be effective, further studies are needed to investigate the best practice to get more women to engage in in-prison prevention programs, e.g., through offering further sexual health education and self-sampling.
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  • 文章类型: Journal Article
    大多数关于月经周期的研究都是基于实验室的,在小样本中,不频繁的采样,仅限于年轻人。这里,我们使用可穿戴和基于日记的数据来调查月经期和年龄对手指温度的影响,睡眠,心率(HR),身体活动,身体症状,和心情。共有116名健康女性,没有月经紊乱,登记:67名年轻人(18-35岁,生殖阶段)和53中年(42-55岁,晚期生殖到更年期过渡)。在一个月经周期内,参与者戴着Oura戒指Gen2来检测手指温度,HR,心率变异性(正常心跳[RMSSD]之间连续差异的均方根),steps,和睡眠。他们使用黄体生成素(LH)试剂盒和每日睡眠,心情,和身体症状。cosinor节律分析用于检测温度的月经振荡。使用分层线性模型评估月经周期阶段和组对所有其他变量的影响。手指温度遵循振荡趋势,表明96名参与者的排卵周期。在中年组,温度节律较高,但是时期,振幅,两组月经和顶期之间的天数相似。在那些温度振荡的人中,两组月经期间HR最低。只有在年轻的群体中,黄体后期的RMSSD低于月经期间。总的来说,RMSSD较低,每天的步数更高,在中年组。在可穿戴衍生或自我报告的睡眠效率测量中未检测到显着的月经周期变化,持续时间,睡后醒来,睡眠发作潜伏期,或睡眠质量。排卵前后情绪阳性较高,和月经期间表现出的身体症状。温度和HR在整个月经周期内发生变化;然而,这些健康的年轻人和中年人的睡眠指标保持稳定.进一步的工作应该在更长的时间内调查是否存在个体或集群特定的睡眠变化,如果缓冲机制可以保护睡眠免受整个月经周期的生理变化。
    Most studies about the menstrual cycle are laboratory-based, in small samples, with infrequent sampling, and limited to young individuals. Here, we use wearable and diary-based data to investigate menstrual phase and age effects on finger temperature, sleep, heart rate (HR), physical activity, physical symptoms, and mood. A total of 116 healthy females, without menstrual disorders, were enrolled: 67 young (18-35 years, reproductive stage) and 53 midlife (42-55 years, late reproductive to menopause transition). Over one menstrual cycle, participants wore Oura ring Gen2 to detect finger temperature, HR, heart rate variability (root mean square of successive differences between normal heartbeats [RMSSD]), steps, and sleep. They used luteinizing hormone (LH) kits and daily rated sleep, mood, and physical symptoms. A cosinor rhythm analysis was applied to detect menstrual oscillations in temperature. The effect of menstrual cycle phase and group on all other variables was assessed using hierarchical linear models. Finger temperature followed an oscillatory trend indicative of ovulatory cycles in 96 participants. In the midlife group, the temperature rhythm\'s mesor was higher, but period, amplitude, and number of days between menses and acrophase were similar in both groups. In those with oscillatory temperatures, HR was lowest during menses in both groups. In the young group only, RMSSD was lower in the late-luteal phase than during menses. Overall, RMSSD was lower, and number of daily steps was higher, in the midlife group. No significant menstrual cycle changes were detected in wearable-derived or self-reported measures of sleep efficiency, duration, wake-after-sleep onset, sleep onset latency, or sleep quality. Mood positivity was higher around ovulation, and physical symptoms manifested during menses. Temperature and HR changed across the menstrual cycle; however, sleep measures remained stable in these healthy young and midlife individuals. Further work should investigate over longer periods whether individual- or cluster-specific sleep changes exist, and if a buffering mechanism protects sleep from physiological changes across the menstrual cycle.
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  • 文章类型: Journal Article
    尽管宫颈癌(CC)是一种可预防的疾病,由于不平等限制了获得保健服务的机会,其发病率在边缘化社区仍然很高。本文调查了经验,感知,在社区参与推动的宫颈癌预防倡议期间,对哥伦比亚亚马逊地区土著妇女筛查的态度。
    基于对Paujil保护区妇女和土著领导人进行访谈的定性研究。他们参与了以宫颈癌预防为重点的研究,它采用了学术界和社区之间的合作方法,旨在增强妇女的健康并减少获得医疗保健服务方面的不平等。分析采用了演绎和归纳法。
    讨论了五个主要主题:“卫生服务中的障碍”;“个人和文化限制”;“动机和促进者”;“研究框架内的积极经验”;和“鼓励妇女参与的建议”。与预约安排和结果交付有关的挑战经常被认为是访问的障碍。错误信息,羞耻感,恐惧,对卫生服务的不信任在不愿接受筛查方面发挥了重要作用。家庭和社区网络的支持等因素,尊重的待遇,易于安排约会,女性医疗保健专业人员的存在,精通土著语言的领导人的参与被认为是筛查接受的积极促进者。
    了解影响筛查机会的因素对于减少土著妇女在提供服务方面的不平等至关重要。能够识别这些因素并激励女性的训练有素的领导者的参与可以对宫颈癌预防计划的接受和指导产生积极影响。
    UNASSIGNED: Despite cervical cancer (CC) being a preventable disease, its incidence remains high in marginalized communities due to inequalities that restrict access to health services. This article investigates the experiences, perceptions, and attitudes regarding the screening of indigenous women in a region of the Colombian Amazon during a cervical cancer prevention initiative facilitated by community participation.
    UNASSIGNED: Qualitative study based on interviews conducted with women and indigenous leaders from Paujil reserve. They participated in research focused on cervical cancer prevention, which employed a methodology of collaboration between academia and communities aimed at enhancing women\'s health and reducing inequalities in access to healthcare services. The analysis utilized a deductive and inductive approach.
    UNASSIGNED: Five main themes were addressed: \'Barriers within health services\'; \'Individual and cultural constraints\'; \'Motivations and facilitators\'; \'Positive experiences within the research framework\'; and \'Suggestions for encouraging women\'s participation.\' Challenges related to appointment scheduling and result delivery were frequently cited as obstacles to access. Misinformation, feelings of shame, fear, and distrust towards health services played significant roles in the reluctance to undergo screening. Factors such as support from family and community networks, respectful treatment, ease of scheduling appointments, the presence of female healthcare professionals, and involvement of leaders fluent in indigenous languages were identified as positive facilitators of screening acceptance.
    UNASSIGNED: Understanding the factors that influence access to screening is crucial for reducing inequalities in service delivery for indigenous women. The involvement of trained leaders who can identify these factors and motivate women can have a positive impact on the acceptance and guidance of cervical cancer prevention programs.
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