Wolff-Parkinson-White

沃尔夫 - 帕金森 - 白色
  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    背景:由于接近正常传导系统,对副通道(PHAP)进行导管消融具有挑战性。回顾性研究表明,与射频消融(RFCA)相比,冷冻消融具有更好的安全性,但复发率更高。这项研究的目的是将电生理学家进行的ParahisianAP消融的结果与两种技术的经验进行比较。
    方法:前瞻性单中心,使用非盲法和1:1模型。患者包括经电生理研究证实的ParahisianAP,并根据当前指南进行射频或冷冻消融。在透视引导下。没有使用电解剖标测。
    结果:2018年10月至2020年2月,共有30名患者(平均年龄25±9.4岁;90%为男性)入选。RFCA和CRYO之间的急性成功率相似(93%与87%,p=0.54)。RFCA的短期复发率没有显着降低(14%与30%,p=0.3)和机械性创伤(6%vs.20%;p=0.28)。随访1年后,两组的长期复发率和无事件生存时间相似(p=0.286)。也没有观察到持续的完全房室传导阻滞或传导紊乱。
    结论:考虑到小样本量的限制和缺乏对RFCA的电解剖标测,采用RFCA的ParahianAP消融术的疗效和安全性与CRYO无差异,由经验丰富的电生理学家执行。两种能量方式均未报告永久性完全性房室传导阻滞的病例。
    BACKGROUND: Catheter ablation of parahisian accessory pathways (PHAP) are challenging due to their proximity to the normal conduction system. Retrospective studies suggest that cryoablation has a better safety profile but a higher recurrence rate when compared to radiofrequency ablation (RFCA). The objective of this study was to compare the results of parahisian AP ablation performed by electrophysiologists with experience in both technologies.
    METHODS: Prospective single-center, non-blinded and 1:1 model was used. Patients included had parahisian AP confirmed by an electrophysiological study and referred for radiofrequency or cryotherapy ablation according to current guidelines, under fluoroscopic guidance. No electroanatomic mapping was used.
    RESULTS: A total of 30 patients (mean age of 25±9.4 years; 90% male) were enrolled between Oct/2018 to Feb/2020. Acute success rate between RFCA and CRYO were similar (93% vs. 87%, p = 0.54). A nonsignificant reduction in short-term recurrence rate for RFCA (14% vs. 30%, p = 0.3) and mechanical trauma (6% vs. 20%; p = 0.28) was observed. Long-term recurrence rate and event-free survival time were similar in both groups after 1-year follow-up (p = 0.286). No persistent complete AV block or conduction disturbance was also observed.
    CONCLUSIONS: Considering the limitation of a small sample size and the lack of use of electroanatomic mapping for RFCA, the efficacy and safety profile of parahisian AP ablation with RFCA was not different from CRYO, when performed by experienced electrophysiologists. No cases of permanent complete AV block were reported with either energy modalities.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    当房室结受损时,辅助通路可以进行原发性房室传导,但在儿童期可能会自发降解。婴儿期手术房间隔缺损修复后,一名青少年男性因医源性完全性房室结传导阻滞出现疲劳,伴随顺行辅助通路退化,导致有症状的缓慢型心律失常.
    When the atrioventricular node is damaged, accessory pathways can perform primary atrioventricular conduction but may spontaneously degrade during childhood. After surgical atrial septal defect repair during infancy, an adolescent male presented with fatigue due to iatrogenic complete atrioventricular node block with a degrading antegrade accessory pathway resulting in symptomatic bradyarrhythmia.
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  • 文章类型: Case Reports
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    文章类型: Case Reports
    Wolff-Parkinson-White(WPW)综合征是一种先天性心脏预激综合征,通过辅助通路在心房和心室之间呈现不受抑制的电传导,有可能危及生命的心律失常。这是一例无症状/未诊断的43岁女性的病例报告,在全身麻醉下右髋关节硬件去除手术中偶然发现WPW模式。识别无症状患者可能很困难,因为心电图可能只有细微的变化,但在存在室上性心动过速的情况下仍然可能危及生命。由于潜在的风险,建议与心脏科进行随访,以建立准确的诊断。识别后,围手术期的麻醉目标是为任何潜在的心律失常做好准备,最小化触发器,并提供适当的随访,以便进行适当的测试以正确诊断和管理WPW。
    Wolff-Parkinson-White (WPW) syndrome is a congenital cardiac preexcitation syndrome that presents with an uninhibited electrical conduction between the atria and ventricles via an accessory pathway that has the potential for life-threatening arrhythmias. This is a case report of an asymptomatic/undiagnosed 43-year-old female with an incidental finding of WPW pattern during hardware removal surgery of the right hip while under general anesthesia. The identification of asymptomatic patients can be difficult because there may be only subtle changes on the electrocardiogram but could still pose as life-threatening in the presence of supraventricular tachycardia. Because of the potential risks, recommendations were given to follow up with the cardiology department to establish an accurate diagnosis. After recognition, the perioperative anesthetic goal was to prepare for any potential arrhythmia, minimize triggers, and provide proper follow-up so that appropriate testing could be conducted to properly diagnose and manage WPW.
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  • 文章类型: Journal Article
    背景:已发布的指南为儿童Wolff-Parkinson-White(WPW)的风险分层提供了建议。没有关于提供者与这些准则的一致性的数据。我们假设儿科心脏病专家(PC)和电生理学家(EP)之间存在明显的实践差异。
    方法:所有患者的记录,年龄8到21岁,在2013年1月1日至2018年12月31日之间的新心电图诊断为WPW,来自单个中心,进行回顾性审查。根据症状和静息心电图结果将受试者分类为以下之一:无症状间歇性WPW,无症状持续性WPW,或有症状的WPW。诊断测试的性能和结果,包括Holter监护仪,事件监视器,运动压力测试(EST),和电生理研究(EPS),被记录下来。主要结果与已发布的指南一致。次要结果是关于心脏性猝死(SCD)风险的讨论。
    结果:在231例新诊断为心电图WPW模式的患者中,对615例患者的遭遇进行了分析(男性占56%;诊断时的平均年龄为13.9±2.5岁)。观察到EP的指南一致性明显高于PC(95%vs.71%,p<0.001)。在SCD风险讨论的文档中,PC和EP之间存在显着的实践差异:EP与EP的96%在PC中39%(p<0.001)。
    结论:儿科WPW的非侵入性和侵入性风险分层存在显著的实践差异,与PC中已发布的指南的一致性较低,与EP相比。该报告强调了在整个儿科心脏病学界提高对当前WPW指南的认识的必要性。
    BACKGROUND: Published guidelines provide recommendations for risk stratification in pediatric Wolff-Parkinson-White (WPW). There are no data on provider concordance with these guidelines. We hypothesized that significant practice variation exists between pediatric cardiologists (PC) and electrophysiologists (EP).
    METHODS: The records of all patients, age 8 to 21 years, with a new ECG diagnosis of WPW between 1/1/2013 and 12/31/2018, from a single center, were retrospectively reviewed. Subjects were categorized on the basis of symptoms and resting ECG findings as one of the following: asymptomatic intermittent WPW, asymptomatic persistent WPW, or symptomatic WPW. The performance and results of diagnostic testing, including Holter monitor, event monitor, exercise stress test (EST), and electrophysiology study (EPS), were recorded. The primary outcome was concordance with published guidelines. A secondary outcome was documentation of a discussion of sudden cardiac death (SCD) risk.
    RESULTS: 615 patient encounters were analyzed in 231 patients with newly diagnosed WPW pattern on ECG (56% male; mean age at diagnosis 13.9 ± 2.5 years). EP were observed to have a significantly higher rate of guideline concordance than PC (95% vs. 71%, p < 0.001). There was significant practice variation between PC and EP in the documentation of a discussion of SCD risk: 96% in EP vs. 39% in PC (p < 0.001).
    CONCLUSIONS: Significant practice variation exists in the non-invasive and invasive risk stratification of pediatric WPW, with lower concordance to published guidelines amongst PC, when compared to EP. This report highlights the need to promote awareness of current WPW guidelines in the pediatric cardiology community at large.
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  • 文章类型: Journal Article
    背景:一些左辅助途径的倾斜过程很少见。一项不完整的电生理研究可能使我们混淆了倾斜辅助途径或两个辅助途径的存在。所有心房和心室电描记图的接近程度,在导管的每个极点,冠状窦内可能是一个新发现。
    方法:一名68岁女性患者出现心律失常伴低血压,需要电复律。她的心电图(ECG)通过辅助途径被解释为心房颤动。我们按照实验室建立的消融方案进行:通过Seldigner技术在右股静脉上进行两次穿刺,并放置导引器(8F和7F),在左股静脉上进行一次穿刺(7F)。本研究采用BIOTRONIK技术(Multicath研究导管),带有2mm尖端电极的不可偏转7F四极导管记录His电描记图,带有5对冠状窦(CS)电极的不可偏转十极导管。在右腔和左腔以及CS内进行附件通路映射。所有进入CS的电描记图显示从近端到远端CS的短AV。最后,在CS内两个远处的心外膜点消融了两个辅助通路记录.
    结论:在两个遥远的地点消融,一个在心室侧,另一个在二尖瓣环,提示存在倾斜辅助途径,同时鉴别诊断存在两个辅助途径。在我们看来,根据上述观点,我们认为这是一个非常罕见的斜AP与心外膜轨迹。在文献综述中以前没有看到沿着CS的电描记图的序列(在这种情况下)。这很重要,不管有多紧急,遵循侵入性电生理学的诊断和治疗方案。
    BACKGROUND: Oblique course of some left accessory pathways is rare An incomplete electrophysiological study may confuse us between an oblique accessory pathway or the presence of two accessory pathways. The proximity of all atrial and ventricular electrograms, at each pole of the catheter, within the coronary sinus may be a novel finding.
    METHODS: A 68-year-old woman patient presented arrhythmias with hypotension requiring electrical cardioversion. Her electrocardiogram (ECG) was interpreted as atrial fibrillation by accessory pathway. We performed with the protocol of ablation stablished in our laboratory: two punctures on the right femoral vein with placement of introducers (8F and 7F) by Seldigner technique and one puncture on the left femoral vein (7F). The study was performed with BIOTRONIK technology (Multicath study catheter), a non-deflectable 7F quadripolar catheter with 2 mm tip electrode to record the His electrogram, a non-deflectable decapolar catheter with 5 pairs of coronary sinus (CS) electrodes. Accessory pathway mapping was performed in right and left cavities and within the CS. All electrograms into CS showed short AV from proximal to distal CS. Finally, ablation of two accessory pathway recordings was achieved at two distant epicardial points within the CS.
    CONCLUSIONS: Ablation at two distant sites, one on the ventricular side and the other on the mitral annulus, suggests the presence of an oblique accessory pathway and at the same time the differential diagnosis of the presence of two accessory pathways. In our point of view according the above, we consider this is a very rare case of oblique AP with epicardial trajectory. The sequence of electrograms (in this case) along the CS has not been seen before in the literature reviewed. It is important, regardless of the urgency, to follow diagnostic and therapeutic protocols in invasive electrophysiology.
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  • 文章类型: Journal Article
    室上性心动过速(SVT)是婴儿最常见的心律失常。一旦确诊,婴儿入院接受抗心律失常治疗,观察后出院。关于再入院和再入院率的风险因素的数据有限,在药物治疗的时候。这项研究的目的是调查诊断为SVT的婴儿的再入院和结局的危险因素。这是一项单中心回顾性研究,对6个月以下婴儿进行了10年的回顾性研究,并记录了SVT。需要手术或导管介入的先天性心脏病婴儿,胎龄小于32周或诊断为房扑或心房颤动被排除.主要结果是出院后31天内再入院。评估了消融和最终停药的长期需求。包括90名患者。β受体阻滞剂是66和28的初始治疗,需要改变药物。19例在出院后31天内再次入院。与早期再入院相关的唯一临床因素是存在心室预激(6/19vs.8/71,p=0.03)。31天内再入院的患者的治疗时间更长(12[11.5,22.0]vs.10[7.5,12.0]个月,p=0.007),并且更有可能进行消融(4/19vs.2/71,p=0.017)。在这个有SVT的婴儿队列中,再入院很常见,心室预激被认为是再入院的危险因素.出院后31天内再入院的婴儿抗心律失常治疗时间更长,更有可能接受导管消融。
    Supraventricular tachycardia (SVT) is the most common arrhythmia in infants. Once diagnosed, infants are admitted for antiarrhythmic therapy and discharged after observation. There are limited data on risk factors for readmission and readmission rates, while on medication. The objective of this study was to investigate risk factors for readmission and outcomes in infants diagnosed with SVT. This is a single-center retrospective study over a 10-year period of infants under 6 months of age with documented SVT. Infants with congenital heart disease requiring surgical or catheter intervention, gestational age less than 32 weeks or diagnosis of atrial flutter or fibrillation were excluded. The primary outcome was readmission within 31 days of hospital discharge. Long term need for ablation and eventual discontinuation of medications were assessed. Ninety patients were included. Beta blockers were the initial therapy in 66 and 28 required a medication change. Nineteen were readmitted within 31 days of discharge. The only clinical factor associated with early readmission was presence of ventricular pre-excitation (6/19 vs. 8/71, p = 0.03). Patients who were readmitted within 31 days had a longer length of treatment (12 [11.5, 22.0] vs. 10 [7.5, 12.0] months, p = 0.007) and were more likely to undergo ablation (4/19 vs. 2/71, p = 0.017). In this cohort of infants with SVT, readmission was common and ventricular pre-excitation was identified as a risk factor for readmission. Infants who were readmitted within 31 days of discharge had longer length of antiarrhythmic therapy and were more likely to undergo catheter ablation.
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