Understanding of how different grasslands types respond to climate change and human activities across different spatial and temporal dimensions is crucial for devising effective strategies to prevent grasslands degradation. In this study, we developed a novel vulnerability assessment model for grasslands that intricately evaluates the combined impact of climate change and human activities. We then applied this model to analyze the vulnerability and driving mechanism of four representative Chinese grasslands to climate change and human activities. Our findings indicate that the vulnerability of the four grasslands would show a pattern of higher in the west and lower in the east under the influence of climate change alone. However, when human activities are factored in, the vulnerability across the four grasslands tends to homogenize, with human activities notably reducing the vulnerability of alpine grasslands in the west and, conversely, increasing the vulnerability of grasslands in the east. Furthermore, our study reveals distinct major environmental drivers of grasslands vulnerability across different regions. The two western alpine grasslands exhibit higher vulnerability to annual mean temperature and isothermality compared to the eastern temperate grasslands, while their vulnerability to precipitation of the coldest quarter is lower than that of the eastern temperate grasslands. These findings are helpful for understanding the multifaceted causes and mechanisms of grasslands degradation, providing a scientific foundation for the sustainable management and conservation of grassland resources.

This ethnographic exploration of death in the Peruvian context draws on fieldwork among abandoned-both by their families and the state-older adults in a shelter for the homeless in Lima, Peru. I examine the conditions and local forces that shape the ways people at this institution socially and physically die. My argument is that people in this long-term care facility who have lived entire lives on the margins, usually, end up having irrelevant deaths to their families, other residents of the institution, and the Peruvian state. At this shelter, dying in an irrelevant way means dying without companionship from family members and receiving poor and flawed care from the institution that shelters them.

UNASSIGNED: Caregivers of autistic persons often face \"courtesy stigma,\" a phenomenon by which caregivers experience stigma because of their association with a person whose disability may be stigmatized. Understanding the repercussions of this stigma is crucial not only for caregivers\' mental health but also for the quality of care provided to their dependent. This study aimed to explore courtesy stigma among caregivers of autistic persons in Quebec, examining its prevalence and impact in order to identify groups that are particularly susceptible to negative outcomes.
UNASSIGNED: This study used a cross-sectional online survey methodology employing quota sampling to collect responses from 194 participants. Data were collected using a computer-assisted web interview (CAWI) platform. The impact of courtesy stigma was measured in terms of care burden, mental health, and overall well-being of caregivers.
UNASSIGNED: The findings revealed that caregivers frequently experience rejection, isolation, and work-related challenges. Notably, caregivers\' health was below average with the lowest reported health outcomes in Quebec. The caregivers who are the most vulnerable to negative outcomes included female caregivers, those aged 45 or older, financially strained households, caregivers of children requiring elevated levels of support, caregivers who isolated due to their autistic dependents, and those who experienced stigmatization directed at themselves or their children in the form of rejection.Interestingly, 60% of respondents reported that the caregiving burden was \"not at all\" to \"somewhat\" difficult, raising questions about factors that may mitigate caregiving challenges over time.
UNASSIGNED: Negative outcomes from courtesy stigma vary depending on certain risk factors and individual characteristic. This study underscores the need for targeted public policies and interventions, particularly for those at a higher risk of experiencing the negative effects of courtesy stigma on the burden of care, overall health, and mental health. By tailoring resources and support for these priority groups, we can better address the challenges faced by families of autistic persons.

Ethics standards reference the need for special consideration of vulnerable populations, such as pregnant women, incarcerated individuals, and minors. The concept of vulnerability is poorly conceptualized in the medical sciences where it originated, and its application to the social sciences is even more challenging. Social science researchers may unwittingly fail to appreciate preexisting vulnerabilities and indeed may be responsible for inducing new research-related vulnerability. In this paper, we present the first comprehensive coding of country-level vulnerability designations. Specifically, we coded all 355 official documents governing social/behavioral human subjects research for the 107 countries with such regulations and identified 68 distinct vulnerability categories. The data reveal substantial regional variation, overemphasis of categories derived from medical sciences, neglect of critical categories such as displacement, and likely heterogeneity within and across groups. The article provides a conceptual framework that shifts the problem away from static, enumerated categories toward emphasis on research-induced vulnerability. Based on our conceptualization and coding, we present a framework for assessing vulnerability and implementing appropriate protections.

Urban infrastructure, important for societal functioning, faces challenges from aging assets and increasing service demands. Traditional asset management practices, often conducted in silos, fail to address the interconnected nature of these systems, leading to inefficiencies and heightened system failure risks. This article combines the spatial and temporal aspects of sewer, water, and road networks to facilitate integrated interventions and enable informed decision-making among diverse stakeholders. The outcome of this research is the creation of interactive hotspot maps on a unified platform, highlighting potential areas for integrated intervention across different infrastructures. To enhance the potential for collaboration in integrated interventions, flexibility in intervention planning was incorporated. With increased flexibility in intervention decisions, the potential for collaboration also increased. For the case study, introducing a 5-year intervention flexibility increased the number of collaborative projects between sewer, water, and roads from 0 to 18. The maps can also indicate areas where the application of trenchless technologies are justifiable. Other important information on asset characteristics for the decision-makers, including age, inspection, deterioration, and other relevant spatial and temporal details can also be obtained from the maps. The presented methodology and findings provide practical solution for utilities to manage urban infrastructure networks more efficiently.

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Objectives (1) To investigate longitudinal associations between grip strength (GS) and cognition over 4 years in European older adults, (2) to examine differences in temporal associations between men and women and between levels of physical activity, (3) to explore in each year 2015 and 2019 associations between GS quartiles and cognitive performance, and (4) to explore longitudinal associations between GS quartiles (year 2015) and cognitive performance (year 2019). Methods: 25,281 individuals (14,200 women) from 17 European countries aged ≥50 years responded to waves 6th and 8th of the SHARE project. We analyzed GS, a general cognition index, and physical activity level. Results: Panel analyses revealed a bidirectional relationship over 4 years between GS and cognition, with differences between sex, as well as between participants with moderate-to-vigorous and low physical activity levels. Conclusion: Women and participants with low physical activity were more likely to experience cognitive performance deficits 4 years later.

System-to-system communication via Application Programming Interfaces (APIs) plays a pivotal role in the seamless interaction among software applications and systems for efficient and automated service delivery. APIs facilitate the exchange of data and functionalities across diverse platforms, enhancing operational efficiency and user experience. However, this also introduces potential vulnerabilities that attackers can exploit to compromise system security, highlighting the importance of identifying and mitigating associated security risks. By examining the weaknesses inherent in these APIs using security open-intelligence catalogues like CWE and CAPEC and implementing controls from NIST SP 800-53, organizations can significantly enhance their security posture, safeguarding their data and systems against potential threats. However, this task is challenging due to evolving threats and vulnerabilities. Additionally, it is challenging to analyse threats given the large volume of traffic generated from API calls. This work contributes to tackling this challenge and makes a novel contribution to managing threats within system-to-system communication through API calls. It introduces an integrated architecture that combines deep-learning models, i.e., ANN and MLP, for effective threat detection from large API call datasets. The identified threats are analysed to determine suitable mitigations for improving overall resilience. Furthermore, this work introduces transparency obligation practices for the entire AI life cycle, from dataset preprocessing to model performance evaluation, including data and methodological transparency and SHapley Additive exPlanations (SHAP) analysis, so that AI models are understandable by all user groups. The proposed methodology was validated through an experiment using the Windows PE Malware API dataset, achieving an average detection accuracy of 88%. The outcomes from the experiments are summarized to provide a list of key features, such as FindResourceExA and NtClose, which are linked with potential weaknesses and related threats, in order to identify accurate control actions to manage the threats.

The rate of major complications and 30-day mortality after surgery for metastatic spinal tumors is relatively high. While most studies have focused on baseline comorbid conditions and operative parameters as risk factors, there is limited data on the influence of other parameters such as sociodemographic or socioeconomic data on outcomes. We retrospectively analyzed data from 165 patients who underwent surgery for spinal metastases between 2012-2023. The primary outcome was development of major complications (i.e., Clavien-Dindo Grade III-IV complications), and the secondary outcome was 30-day mortality (i.e., Clavien-Dindo Grade V complications). An exploratory data analysis that included sociodemographic, socioeconomic, clinical, oncologic, and operative parameters was performed. Following multivariable analysis, independent predictors of Clavien-Dindo Grade III-IV complications were Frankel Grade A-C, lower modified Bauer score, and lower Prognostic Nutritional Index. Independent predictors of Clavien-Dindo Grade V complications) were lung primary cancer, lower modified Bauer score, lower Prognostic Nutritional Index, and use of internal fixation. No sociodemographic or socioeconomic factor was associated with either outcome. Sociodemographic and socioeconomic factors did not impact short-term surgical outcomes for metastatic spinal tumor patients in this study. Optimization of modifiable factors like nutritional status may be more important in improving outcomes in this complex patient population.

UNASSIGNED: With increasing prevalence of surgery under local or regional anesthesia, which allows patients to remain conscious during the intraoperative phase, there is a growing need to comprehend the lived experiences associated with this practice.
UNASSIGNED: This study aimed to illuminate the lived experiences of individuals who remained conscious during surgical intervention under local or regional anesthesia.
UNASSIGNED: A qualitative design was chosen.
UNASSIGNED: Participants in the present study were recruited from three surgical wards located in central Sweden using a purposive sampling strategy. The surgical disciplines included ear, gynecological, hernioplasty, orthopedic, and vessel surgeries.
UNASSIGNED: Fourteen narrative interviews were conducted with individuals who had undergone elective surgery while conscious.
UNASSIGNED: Verbatim transcribed text was analyzed using a phenomenological-hermeneutic method.
UNASSIGNED: The lived experience of being conscious during surgery was marked by feelings of hope alongside a sense of losing one\'s identity and experiencing destabilization. Structural analysis revealed two themes. The first theme, \'being in the hands of others\', encompassed subthemes such as \'entering an unfamiliar environment and procedure,\' \'losing foothold and a sense of self-identity,\' and \'enduring unexpected or anticipated discomfort.\' The second theme, \'managing the inevitable for future health concerns,\' involved subthemes such as \'pursuing self-acceptance of the situation,\' \'entrusting the professionals while seeking signs of a smooth procedure,\' and \'Enhancing own resilience through continuous support.
UNASSIGNED: Beyond the patient\'s physical well-being during surgery, the OR team should acknowledge the \"person\" component and focus on their emotional and social needs in this vulnerable situation. The four meta-paradigms of nursing-person, health, environment, and nursing-significantly influence the conscious patient\'s experience.
UNASSIGNED: No patient or public contribution.