■关于急性呼吸道疾病(ARI)和呼吸道病毒传播的数据有限,特别是学校。为了更好地描述学校ARI和呼吸道病毒的流行病学特征,我们开发了学校传染病的学校知识(学校孩子)。
■学校孩子是潜在的,在堪萨斯城的一个大城市学区(幼儿园前12年级)的呼吸道病毒测试计划,密苏里州。在2022-2023学年,所有学生和教职员工均有资格通过每月提交观察到的自给鼻拭子来参加学校的呼吸道病毒监测检查.当出现≥1ARI症状时,参与者还可以提交鼻拭子进行按需症状测试。包括咳嗽,发烧,鼻塞,流鼻涕,呼吸急促,喉咙痛,和/或喘息。使用多病原体呼吸聚合酶链反应测定法在研究实验室中测试了拭子。通过收集每周两次的鼻拭子来评估参与者的持续病毒脱落情况(即,恢复期),在最初的按需症状测试之后。要求参与者在收集呼吸拭子之前完成电子调查以捕获ARI症状的存在和类型。
■从2022年10月31日至2023年6月29日,学校儿童注册了978名参与者,包括700名学生,占地区学生人数的3.4%,278名工作人员。参与者提交了中位数为六次的监测,一种症状,和研究期间的两个疗养标本。共有6,315份呼吸道标本,包括4700个监控,721按需症状,和894个疗养标本,进行了测试。总的来说,在1,168份(24.9%)监测和363份(50.3%)有症状的样本中发现了一种病毒。在预定的监测测试之前发送给参与者的5538项症状调查中,完成4,069(73.5%);在1,348(33.1%)调查中报告了ARI症状。
■在学校进行呼吸监测测试是可行的,并为上学的学生和教职员工提供了有关呼吸道病毒检测的新信息。学校是一个重要的社区环境,以及更好地了解学校的呼吸道病毒传播可能有助于识别社区中的呼吸道病毒传播,并评估有效的感染预防措施的影响。
UNASSIGNED: Limited data about acute respiratory illness (ARI) and respiratory virus circulation are available in congregate community settings, specifically schools. To better characterize the epidemiology of ARI and respiratory viruses in schools, we developed School Knowledge of Infectious Diseases in Schools (School KIDS).
UNASSIGNED: School KIDS is a prospective, respiratory viral testing program in a large metropolitan school district (pre-kindergarten-12th grade) in Kansas City, Missouri. During the 2022-2023 school year, all students and staff were eligible to participate in surveillance respiratory viral testing at school by submitting observed self-administered nasal swabs monthly. Participants could also submit a nasal swab for on-demand symptomatic testing when experiencing ≥1 ARI symptom, including cough, fever, nasal congestion, runny nose, shortness of breath, sore throat, and/or wheezing. Swabs were tested in a research laboratory using multipathogen respiratory polymerase chain reaction assays. Participants were evaluated for ongoing viral shedding by collecting two weekly nasal swabs (i.e., convalescent), following initial on-demand symptomatic testing. Participants were asked to complete an electronic survey to capture the presence and type of ARI symptom(s) before the collection of respiratory swabs.
UNASSIGNED: From 31 October 2022 to 29 June 2023, School KIDS enrolled 978 participants, including 700 students, representing 3.4% of the district student population, and 278 staff members. Participants submitted a median of six surveillance, one symptomatic, and two convalescent specimens during the study period. A total of 6,315 respiratory specimens, including 4,700 surveillance, 721 on-demand symptomatic, and 894 convalescent specimens, were tested. Overall, a virus was detected in 1,168 (24.9%) surveillance and 363 (50.3%) symptomatic specimens. Of the 5,538 symptom surveys sent to participants before scheduled surveillance testing, 4,069 (73.5%) were completed; ARI symptoms were reported on 1,348 (33.1%) surveys.
UNASSIGNED: Respiratory surveillance testing in schools is feasible and provides novel information about respiratory virus detections in students and staff attending school. Schools are an important community setting, and better knowledge of respiratory virus circulation in schools may be useful to identify respiratory virus transmission in the community and assess the impact of effective infection prevention measures.