虽然美国亚洲和太平洋岛民成年人的25-羟维生素D(25(OH)D)水平低于白人成年人,种族亚组数据仍然有限.在大量的加州人口中,与白人成年人相比,亚洲/太平洋岛民的25(OH)D<20ng/mL(50nmol/L)的调整后患病率高1.5至2.7倍,因种族而异。
目标:美国亚洲及太平洋岛民(PI)成年人的25-羟维生素D[25(OH)D]水平通常低于非西班牙裔白人(NHW)成年人,但分组数据仍然有限。我们比较了年龄较大的亚洲/PI和NHW成年人中25(OH)D的性别和种族特异性患病率。
方法:来自102,556名亚洲/PI和381,724名年龄在50-89岁的NHW成年人的数据,在2012-2019年测量了25(OH)D和体重指数(BMI,在±1年内)在加利福尼亚州的医疗保健系统中进行了检查。通过种族和种族检查低25(OH)D<20ng/mL(50nmol/L)。协变量包括年龄,吸烟,BMI,测量的季节。改进的泊松回归用于估计患病率比率(aPR),调整协变量。
结果:在31,287名亚洲/PI男性和71,269名亚洲/PI女性中,低25(OH)D患病率分别为22.6%和14.7%,分别,显著高于122,162名NHW男性(12.3%)和259,562名NHW女性(9.9%)。在亚洲/PI亚组中,25(OH)D低患病率为17%至18%(韩国,日本人,菲律宾人),22%至24%(中国,越南语),28%(南亚),男性中35%(夏威夷原住民/PI)和11%至14%(日本,菲律宾人,中文,韩语),17%至18%(南亚,越南语),26%(夏威夷原住民/PI)的女性。男性和女性的相应aPR(NHW参考)如下:夏威夷原住民/PI,2.70和2.34;南亚,2.56和2.07;越南语,2.17和2.31;中文,2.04和1.89;韩语,1.60和1.85;菲律宾人,1.58和1.52;和日语,1.58和1.49(p<0.001)。
结论:在美国庞大的老年亚裔/PI成年人医疗保健人群中,与NHW成人相比,亚洲/PI的低25(OH)D患病率高1.5至2.7倍,因性别和种族而异。
While US Asian and Pacific Islander adults have lower 25-hydroxyvitamin D (25(OH)D) levels than White adults, ethnic subgroup data remain limited. In a large California population, the adjusted prevalence of 25(OH)D < 20 ng/mL (50 nmol/L) was 1.5- to 2.7-fold higher for Asian/Pacific Islander compared to White adults, with substantial variation by ethnicity.
OBJECTIVE: US Asian and Pacific Islander (PI) adults generally have lower 25-hydroxyvitamin D [25(OH)D] levels than non-Hispanic White (NHW) adults, but subgroup data remain limited. We compared sex- and ethnicity-specific prevalence of low 25(OH)D among older Asian/PI and NHW adults.
METHODS: Data from 102,556 Asian/PI and 381,724 NHW adults aged 50-89 years with measured 25(OH)D in 2012-2019 and body mass index (BMI, within ± 1 year) were examined in a California healthcare system. Low 25(OH)D < 20 ng/mL (50 nmol/L) was examined by race and ethnicity. Covariates included age, smoking, BMI, and season of measurement. Modified Poisson regression was used to estimate prevalence ratios (aPR), adjusting for covariates.
RESULTS: Among 31,287 Asian/PI men and 71,269 Asian/PI women, the prevalence of low 25(OH)D was 22.6% and 14.7%, respectively, significantly higher than observed for 122,162 NHW men (12.3%) and 259,562 NHW women (9.9%). Within Asian/PI subgroups, low 25(OH)D prevalence ranged from 17 to 18% (Korean, Japanese, Filipino), 22 to 24% (Chinese,
Vietnamese), 28% (South Asian), and 35% (Native Hawaiian/PI) among men and 11 to 14% (Japanese, Filipina, Chinese, Korean), 17 to 18% (South Asian,
Vietnamese), and 26% (Native Hawaiian/PI) among women. The corresponding aPRs (NHW reference) for men and women were as follows: Native Hawaiian/PI, 2.70 and 2.34; South Asian, 2.56 and 2.07;
Vietnamese, 2.17 and 2.31; Chinese, 2.04 and 1.89; Korean, 1.60 and 1.85; Filipino, 1.58 and 1.52; and Japanese, 1.58 and 1.49 (p < 0.001).
CONCLUSIONS: In a large US healthcare population of older Asian/PI adults, low 25(OH)D prevalence was 1.5- to 2.7-fold higher for Asian/PI compared to NHW adults, with substantial variation by sex and ethnicity.