Version, Fetal

版本,胎儿
  • 文章类型: Journal Article
    背景:头颅外型(ECV)是一种医疗程序,其中进行体外操作以使臀位(BP)胎儿处于头位。在各种随机临床试验(RCT)中已经评估了使用麻醉来促进重新定位,但其潜在的有效性仍存在争议。
    方法:在8个电子数据库中进行了系统的文献检索。在荟萃分析中,随机效应模型用于计算合并相对风险(RR)及其95%置信区间(CI),以及合并的标准化平均差(SMD)及其95%CI,以便系统地评估麻醉对ECV成功率的影响,阴道分娩,剖宫产以及其他结局。相关的亚组分析,还进行了发表偏倚检验和敏感性分析.
    结果:本综述包括17项随机对照试验。接受麻醉的女性成功ECV(RR:1.37,95%CI:1.19-1.58)和阴道分娩(RR:1.23,95%CI:1.03-1.47)的发生率明显较高,剖宫产发生率显着降低(RR:0.69,95%CIs:0.53-0.91),与那些没有的人相比。
    结论:麻醉的给药不仅显著减轻了产妇的疼痛,而且显著提高了足月妊娠妇女ECV的成功率,导致阴道分娩的发生率显著上升。然而,可能增加产妇低血压的发生率。
    背景:该协议在PROSPERO进行了前瞻性注册,注册CRD42022381552。
    BACKGROUND: External cephalic version (ECV) is a medical procedure in which an extracorporeal manipulation is performed to render the breech presentation (BP) fetus in the cephalic position. The use of anesthesia to facilitate repositioning has been evaluated in various randomized clinical trials (RCTs), but its potential effectiveness remains controversial.
    METHODS: A systematic literature search was carried out in 8 electronic databases. In the meta-analysis, a random effects model was used to calculate the pooled relative risk (RR) and its 95% confidence interval (CI), and the pooled standardized mean difference (SMD) and its 95% CI, in order to systematically assess the effect of anesthesia on the success rates of ECV, vaginal delivery, cesarean delivery as well as other outcomes. Relevant subgroup analyses, publication bias test and sensitivity analyses were also conducted.
    RESULTS: This review included 17 RCTs. Women who received anesthesia had a significantly higher incidence of successful ECV (RR: 1.37, 95% CIs: 1.19-1.58) and vaginal delivery (RR: 1.23, 95% CIs: 1.03-1.47), and a significantly lower incidence of cesarean delivery (RR: 0.69, 95% CIs: 0.53-0.91), compared with those who did not.
    CONCLUSIONS: The administration of anesthesia not only significantly reduces maternal pain but also significantly increases the success rate of ECV in women with malpresentation at term, leading to a significant rise in the incidence of vaginal delivery. However, it may increase the incidence of maternal hypotension.
    BACKGROUND: The protocol was prospectively registered with PROSPERO, registration CRD42022381552.
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  • 文章类型: English Abstract
    Objective: To explore the feasibility of using ultrasonic convex array probe compressing abdominal wall to increase success rate of external cephalic version (ECV) without anesthesia in full-term and near-term pregnancy. Methods: Totally 190 singleton and non-cephalic presentation pregnant women in 36-39+4 weeks of gestation performed ECV from April 2019 to August 2023 in the First Affiliated Hospital of Nanjing Medical University were analyzed. According to whether use the ultrasound probe compressing fetal breech or not, the pregnant women were divided into two groups: 81 cases in the probe-compressing group (including primipara 61 cases and multipara 20 cases) and 109 cases in the non-probe-compressing group(including primipara 72 cases and multipara 37 cases). Clinical data, ECV related factors and complications were analyzed and compared between the two groups. Results: (1) The overall success rate of ECV was 64.2% (122/190). There was no significant difference in the success rate of ECV between probe-compressing group and non-probe-compressing group [69.1% (56/81) vs 60.6% (66/109), χ2=1.490, P=0.222]. The total vaginal delivery rate after successful ECV was 81.1% (99/122), while 71.1% (54/76) in primipara and 97.8% (45/46) in multipara, respectively. (2) Compare to the non-probe-compressing group, the success rate of ECV in primipara was significantly higher in the probe-compressing group [45.8% (33/72) vs 70.5% (43/61)], but the gestational age was shorter and the height was higher in the probe-compressing group (all P<0.05). The success rate of ECV of multipara in the probe-compressing group (65.0%, 13/20) was lower than that in the non-probe-compressing group (89.2%, 33/37), but there was no significant difference between the two groups (P>0.05). (3) Multivariate logistic regression analysis showed that abdominal wall compressed by ultrasound probe (OR=2.601, 95%CI: 1.113-6.075; P=0.027) and amniotic fluid index (AFI; OR=1.010, 95%CI: 1.001-1.020; P=0.028) were positive factors for the successful rate of ECV in primipara pregnant women. (4) The main complication of ECV was transient fetal heart rate reduction (8.9%,17/190), the incidence in the probe-compressing group was significantly higher than that in the non-probe-compressing group [14.8% (12/81) vs 4.6% (5/109); χ2=5.967, P=0.015]. No statistical differences were found in rates of complications between the ECV successful and unsuccessful pregnant women, and between probe-compressing and non-probe-compressing groups (all P>0.05). No adverse maternal and neonatal outcomes related to ECV were observed. Conclusions: The ultrasonic convex array probe compressing could significantly improve the success rate of ECV in primipara without increasing the incidence of adverse maternal and fetal outcomes. The success rate of ECV in primipara is influenced by AFI and operation mode.
    目的: 探讨腹部超声凸阵探头可视化下加压推离胎臀提高无麻醉下足月及近足月臀位外倒转术(ECV)成功率的可行性。 方法: 收集2019年4月至2023年8月南京医科大学第一附属医院190例妊娠36~39+4周、单胎臀位行ECV孕妇的临床资料,根据是否应用腹部超声凸阵探头可视化下加压(即探头加压法)推离胎臀分为加压组(81例,其中初产妇61例、经产妇20例)及未加压组(109例,其中初产妇72例、经产妇37例)。分析比较加压组与未加压组孕妇的临床特点、ECV成功率、并发症及分娩结局。 结果: (1)总体ECV成功率为64.2%(122/190),其中,加压组与未加压组孕妇的ECV成功率分别为69.1%(56/81)与60.6%(66/109),两组比较,差异无统计学意义(χ2=1.490,P=0.222)。ECV成功后阴道分娩率为81.1%(99/122),其中,经产妇与初产妇的阴道分娩率分别为97.8%(45/46)、71.1%(54/76)。(2)加压组初产妇的ECV成功率高于未加压组初产妇[分别为70.5%(43/61)、45.8%(33/72)],且加压组初产妇的身高更高、行ECV时孕周更小,分别比较,差异均有统计学意义(P均<0.05);加压组经产妇的ECV成功率(65.0%,13/20)低于未加压组经产妇(89.2%,33/37),但两组比较,差异无统计学意义(P>0.05)。(3)初产妇ECV成功率的多因素logistic回归分析结果显示,采用探头加压法(OR=2.601,95%CI为1.113~6.075;P=0.027)、羊水指数(OR=1.010,95%CI为1.001~1.020;P=0.028)均是初产妇ECV成功的影响因素。(4)ECV的并发症主要为一过性胎心率减慢(8.9%,17/190),其中,加压组的发生率显著高于未加压组[分别为14.8%(12/81)、4.6%(5/109);χ2=5.967,P=0.015]。其他并发症在ECV成功与失败孕妇中、加压组与未加压组孕妇中分别比较,差异均无统计学意义(P均>0.05)。所有孕产妇及新生儿未发生与ECV相关的不良母儿结局。 结论: 采用探头加压法可明显提高初产妇的ECV成功率,且不增加母儿不良结局的发生,初产妇ECV成功率受操作方法和羊水量的影响。.
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  • 文章类型: Journal Article
    背景:胎头错位,定义为枕骨横向或后部位置,发生在大约5%的新生儿中。在宫颈完全扩张时,胎儿位置不正与阴道旋转分娩的风险增加有关.有三种不同的旋转方法:手动旋转,旋转室或旋转(Kielland\'s)镊子。在缺乏有力证据的情况下,目前还不知道这三种方法中哪一种最有效,对父母和婴儿最安全。
    目的:为了更深入地了解轮产的观点和偏好,探索比较不同轮产方法的随机试验的可接受性和可行性。
    方法:英国母胎医学会通过电子邮件向产科医生发送了一项调查,以及英国正在进行研究的产科医生和活跃的学者。问题集中在感知能力上,首选轮换方法,位置(剧院或劳动室),愿意招募到RCT,及其结果度量。已结束的问题之后是自由文本选项,以允许进一步评论。自由文本答案经过了主题分析。
    结果:252名顾问产科医生回答。大多数人表示他们有能力执行手动轮换(88.1%)。一半的人感到熟练使用Kielland的旋转镊子(54.4%)。大多数产科医生认为熟练使用旋转腹腔(76.2%)。在枕骨横向和后部位置的情况下,手动旋转是首选的第一种旋转方法。许多人认为首先尝试哪种旋转方法的决定取决于案例。三分之二的产科医生通常会在手术室进行轮产(67.9%)。超过一半(52%)不常规使用产时超声检查。大多数(62.7%)愿意招募到比较手动和仪器旋转的随机对照试验。如果一半以上(57.2%)的人愿意招募相同的RCT,如果他们是最资深的轮流阴道分娩监督大三学生的医生。
    结论:在英国进行阴道轮换分娩的实践范围很广。研究不同轮换方法对结果的影响的RCT是可行和可取的,特别是在研究活跃的医院。
    BACKGROUND: Malposition of the fetal head, defined as occiput transverse or posterior positions, occurs in approximately 5% of births. At full cervical dilatation, fetal malposition is associated with an increased risk of rotational vaginal birth. There are three different rotational methods: manual rotation, rotational ventouse or rotational (Kielland\'s) forceps. In the absence of robust evidence, it is not currently known which of the three methods is most efficacious, and safest for parents and babies.
    OBJECTIVE: To gain greater insights into opinions and preferences of rotational birth to explore the acceptability and feasibility of performing a randomised trial comparing different rotational methods.
    METHODS: A survey was sent via email to obstetricians from the British Maternal Fetal Medicine Society, as well as expert obstetricians and active academics in ongoing research in the UK. The questions focussed on perceived competence, preferred rotational method, location (theatre or labour room), willingness to recruit to an RCT, and its outcome measures. Closed questions were followed by the option of free text to allow further comments. The free text answers underwent thematic analysis.
    RESULTS: 252 consultant obstetricians responded. The majority stated they were competent in performing manual rotation (88.1%). Half felt proficient using Kielland\'s rotational forceps (54.4%). Most obstetricians felt skilled in rotational ventouse (76.2%). Manual rotation was the preferred first rotational method of choice in cases of both occiput transverse and posterior positions. The decision for which rotational method to attempt first was considered case-dependent by many. Two thirds of obstetricians would usually conduct rotational births in theatre (67.9%). Over half (52%) do not routinely use intrapartum ultrasound. Most (62.7%) would be willing to recruit to a randomised controlled trial comparing manual versus instrumental rotation. Over half (57.2%) would be willing to recruit to the same RCT if they were the most senior doctor competent in rotational vaginal birth supervising a junior.
    CONCLUSIONS: There is a wide range of practice in conducting rotational vaginal births in the UK. An RCT to investigate the impact of different rotational methods on outcome would be both feasible and desirable, especially in research-active hospitals.
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  • 文章类型: Randomized Controlled Trial
    背景:头颅外型是一种用于在分娩前将胎儿从臀位转向头位的手术。外部头部版本的成功率会受到各种因素的影响;但是,膀胱容量对头颅外型成功率的影响仍存在争议。
    目的:本研究旨在通过一项前瞻性随机研究确定膀胱状态(满或空)对外头型成功率的影响。
    方法:这是一项在三级护理产科中心进行的前瞻性随机对照试验。总的来说,70名接受外头手术的足月有单胎臀位的妇女被随机分为两组:外头手术伴膀胱空膀胱和外头手术伴膀胱全膀胱。由经验丰富的产科医生在超声引导下进行外部头颅手术。主要结果是外部头部版本的成功率。
    结果:全膀胱组外头型成功率为67.56%(25/37),空膀胱组成功率为54.54%(18/33),两组之间无统计学差异(P=0.26)。此外,成功的外部头颅版本的相对风险为1.23(95%置信区间,0.84-1.81),表明无显著差异。
    结论:这项随机对照试验表明,在足月有单胎臀位表现的女性中,膀胱充满或空的存在并不会显著影响头颅外的成功率。我们的发现表明,接受外头手术的女性不需要有一个完整的膀胱来提高手术的成功率。
    External cephalic version is a procedure used to turn a fetus from a breech position to a cephalic position before delivery. The success rate of the external cephalic version can be affected by various factors; however, the effect of bladder volume on the success rate of the external cephalic version remains controversial.
    This study aimed to determine the effect of urinary bladder status (full or empty) on the success rate of the external cephalic version through a prospective randomized study.
    This was a prospective randomized controlled trial conducted at a tertiary care obstetrical center. Overall, 70 women with a singleton breech presentation at term undergoing external cephalic version were randomly allocated into 2 groups: external cephalic version with an empty bladder and external cephalic version with a full bladder. The external cephalic version procedure was performed by experienced obstetricians under ultrasound guidance. The primary outcome was the success rate of the external cephalic version.
    The success rate of the external cephalic version was 67.56% (25/37) in the full bladder group and 54.54% (18/33) in the empty bladder group, with no statistically significant difference between the groups (P=.26). In addition, the relative risk of successful external cephalic version was 1.23 (95% confidence interval, 0.84-1.81), indicating no significant difference.
    This randomized controlled trial demonstrated that the presence of a full or empty urinary bladder does not significantly affect the success rate of the external cephalic version in women with singleton breech presentation at term. Our findings suggest that women undergoing an external cephalic version do not need to have a full bladder to improve the success rate of the procedure.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    目的:回顾目前可用的或正在开发的决策辅助工具,以预测患者的外头版本(ECV)成功的几率。
    方法:我们搜索了PubMed/MEDLINE,CochraneCentral,以及2015-2022年的ClinicalTrials.gov。还包括2015年前系统审查的文章。我们选择了描述或评估模型(预测规则)的英文文章,旨在预测单个患者的ECV结果。可接受的模型结果包括ECV尝试后的头颅表现以及ECV是否最终导致阴道分娩。两位作者根据PRISMA2020指南独立进行了文章选择。自2015年以来,380个独特的记录进行了标题和摘要筛选,49份报告进行了全文审查。最终,包括17篇新文章和8篇来自先前审查的文章。在25篇文章中,22个提出的1-2个模型,每个模型总共25个,而其余3篇文章验证了以前的模型,没有提出新的模型。
    结果:在17篇新文章中,10低,6中度,和1高风险的偏见。几乎所有文章都来自欧洲(11/25)或亚洲(10/25);在过去的20年中,只有一项研究来自美国。发现的模型有不同的演示文稿,包括得分图,决策树(流程图),和方程式。大多数(13/25)没有任何形式的验证,只有5/25达到了外部验证。只有纽曼-孔雀模型(美国,1993)被反复外部验证(巴基斯坦,2012年葡萄牙,2018)。大多数模型(14/25)是在过去5年中发布的。总的来说,较新的型号设计得更坚固,使用更大的样本量,数学上更严格。因此,尽管他们等待进一步的验证,这些模型有很大的潜力比纽曼-孔雀模型更具预测性。
    结论:只有Newman-Peacock模型可以正常临床使用。许多较新的模型很有希望,但需要进一步验证。
    To review the decision aids currently available or being developed to predict a patient\'s odds that their external cephalic version (ECV) will be successful.
    We searched PubMed/MEDLINE, Cochrane Central, and ClinicalTrials.gov from 2015 to 2022. Articles from a pre-2015 systematic review were also included. We selected English-language articles describing or evaluating models (prediction rules) designed to predict an outcome of ECV for an individual patient. Acceptable model outcomes included cephalic presentation after the ECV attempt and whether the ECV ultimately resulted in a vaginal delivery. Two authors independently performed article selection following PRISMA 2020 guidelines. Since 2015, 380 unique records underwent title and abstract screening, and 49 reports underwent full-text review. Ultimately, 17 new articles and 8 from the prior review were included. Of the 25 articles, 22 proposed one to two models each for a total of 25 models, while the remaining 3 articles validated prior models without proposing new ones.
    Of the 17 new articles, 10 were low, 6 moderate, and 1 high risk of bias. Almost all articles were from Europe (11/25) or Asia (10/25); only one study in the last 20 years was from the United States. The models found had diverse presentations including score charts, decision trees (flowcharts), and equations. The majority (13/25) had no form of validation and only 5/25 reached external validation. Only the Newman-Peacock model (United States, 1993) was repeatedly externally validated (Pakistan, 2012 and Portugal, 2018). Most models (14/25) were published in the last 5 years. In general, newer models were designed more robustly, used larger sample sizes, and were more mathematically rigorous. Thus, although they await further validation, there is great potential for these models to be more predictive than the Newman-Peacock model.
    Only the Newman-Peacock model is ready for regular clinical use. Many newer models are promising but require further validation.
    · 25 ECV prediction models have been published; 14 were in the last 5 years.. · The Newman-Peacock model is currently the only one with sufficient validation for clinical use.. · Many newer models appear to perform better but await further validation..
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  • DOI:
    文章类型: Meta-Analysis
    这项研究的目的是检查瑞芬太尼在臀位表现中对头颅外型(ECV)的疗效。使用PubMed进行了广泛的搜索,科克伦图书馆,和其他灰色文学。仅包括使用瑞芬太尼用于ECV的随机对照试验。使用风险比(RR)和平均差异(MD)来估计结果,并使用风险偏差和等级系统评估证据质量。分析了由602名患者组成的五项研究。瑞芬太尼导致ECV成功率适度增加(RR,1.19;95%CI,1.00至1.43;P=0.05),疼痛评分大幅降低(MD,-2.02;95%CI,-2.32至-1.72;P<.00001),短暂性胎儿心动过缓较少(RR,0.40;95%CI,0.19至0.85;P=.02)。然而,瑞芬太尼不影响剖宫产率,(RR,0.97;95%CI,0.49至1.93;P=.93)工具交付(RR,0.94;95%CI,0.41至2.15;P=0.89),和自发分娩率(RR,1.02;95%CI,0.78~1.35;P=0.87)。用瑞芬太尼治疗的母亲患者满意度评分更高。瑞芬太尼的使用可能是ECV的良好策略。然而,将这一发现外推到临床环境必须考虑研究的局限性.
    The purpose of this study was to examine the efficacy of remifentanil on external cephalic version (ECV) in breech presentation. An extensive search was conducted using PubMed, Cochrane Library, and other grey literature. Only randomized controlled trials using remifentanil for ECV were included. Risk ratio (RR) and mean difference (MD) were used to estimate outcomes and quality of evidence was assessed using the Risk of Bias and GRADE system. Five studies consisting of 602 patients were analyzed. Remifentanil resulted in a moderate increase in ECV success rate (RR, 1.19; 95% CI, 1.00 to 1.43; P = .05), a large reduction of pain score (MD, -2.02; 95% CI, -2.32 to -1.72; P < .00001) with fewer transient fetal bradycardia (RR, 0.40; 95% CI, 0.19 to 0.85; P = .02). However, remifentanil did not affect cesarean section rates, (RR, 0.97; 95% CI, 0.49 to 1.93; P = .93) instrumental delivery (RR, 0.94; 95% CI, 0.41 to 2.15; P = 0.89), and spontaneous delivery rate (RR, 1.02; 95% CI, 0.78 to 1.35; P = 0.87). Mothers treated with remifentanil have a higher patient satisfaction score. The use of remifentanil may be a good strategy for ECV. However, extrapolation of this finding to clinical settings must consider the study limitations.
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  • 文章类型: Journal Article
    目的:子宫异常(UA)发生率高达6.7%。臀位发生UA的可能性要高出八倍,在怀孕前可能无法诊断,并且可能仅在臀位的妊娠晚期发现。该研究的目的是评估妊娠36周以来已知和新超声诊断的臀位UA的患病率及其对外头型(ECV)的影响,分娩选择和围产期结局。
    方法:我们在Charité大学医院招募了469名妊娠36周的臀位女性,柏林。进行超声检查以排除UA。确定了已知和新诊断出异常的患者,并分析了分娩选择和围产期结局。
    结果:发现与妊娠前的诊断相比,在妊娠36-37周时对UA的“从头”诊断明显更高,分别为4.5%和1.5%(p<0.001和比值比4,95%置信区间为2.12-7.69)。发现的异常包括53.6%的双目独科利斯,39.3%subseptus,3.6%独角兽和3.6%didelphys。尝试进行阴道臀位分娩的试验在55.5%的病例中成功。没有成功的ECV。
    结论:臀位是子宫畸形的标志。即使在ECV之前妊娠36周以确定遗漏的异常,妊娠中的聚焦超声筛查也可以使臀位UA的诊断提高四倍。及时诊断有助于产前护理和分娩计划。重要的是,产后可计划明确的诊断和治疗,以改善未来妊娠结局.ECV在选定病例中的作用有限。
    OBJECTIVE: Uterine anomalies (UA) occur in up to 6.7% of women. Breech is eight times more likely to occur with UA which may not be diagnosed prior to pregnancy and may only be found in the third trimester with breech. The objective of the study is to assess the prevalence of both already known and newly sonographically diagnosed UA in breech from 36 weeks of gestation and its impact on external cephalic version (ECV), delivery options and perinatal outcomes.
    METHODS: We recruited 469 women with breech at 36 weeks of gestation over a 2-year period at the Charité University Hospital, Berlin. Ultrasound examination was performed to rule out UA. Patients with known and newly \'de novo\' diagnosed anomalies were identified and delivery options and perinatal outcomes analyzed.
    RESULTS: The \'de novo\' diagnosis of UA at 36-37 weeks of pregnancy with breech was found to be significantly higher compared to the diagnosis prior to pregnancy with 4.5% vs 1.5% (p < 0.001 and odds ratio 4 with 95% confidence interval 2.12-7.69). Anomalies found included 53.6% bicornis unicollis, 39.3% subseptus, 3.6% unicornis and 3.6% didelphys. A trial of vaginal breech delivery was successful in 55.5% of cases when attempted. There were no successful ECVs.
    CONCLUSIONS: Breech is a marker for uterine malformation. Diagnosis of UA with breech can be up to four times improved with focused ultrasound screening in pregnancy even from 36 weeks of gestation prior to ECV to identify missed anomalies. Timely diagnosis aids antenatal care and delivery planning. Importantly, definitive diagnosis and treatment can be planned postpartum to improve outcomes in future pregnancies. ECV plays a limited role in selected cases.
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  • 文章类型: Journal Article
    我们报道了产时超声检查的新应用,本文用于辅助横卧的第二双胞胎的内部podalic版本和阴道分娩。第一个头双胞胎的阴道分娩后,内部podalic版本是在连续超声视觉下进行的,导致健康新生儿的臀位分娩简单。
    We report a novel application of intrapartum sonography, herein used to assist the internal podalic version and the vaginal delivery of a transverse-lying second twin. Following the vaginal delivery of the first cephalic twin, the internal podalic version was performed under continuous ultrasound vision, leading to the uncomplicated breech delivery of a healthy neonate.
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  • 文章类型: Letter
    暂无摘要。
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