UNASSIGNED:颅骨成形术和脑室腹膜分流术的组合是去骨瓣减压术(DC)后脑积水患者的治疗策略。然而,同时与分期手术在减少术后并发症方面尚未最终确定。这是相关研究的荟萃分析,以评估同时手术是否显着降低术后并发症的风险。与分阶段手术相比。
未经授权:我们系统地搜索了PubMed,Embase,科克伦,用于研究的科学数据库(2022年5月11日发布),比较接受并发和分期颅骨成形术和脑室腹膜分流术的患者。我们的主要终点是;总体术后并发症,术后出血,术后感染和再次手术。我们使用随机效应模型评估合并数据,以使用比值比(ORs)和95%置信区间(CIs)比较并发症发生率。
未经批准:在494项确定的研究中,我们的分析包括12名(N=651名参与者)。与分期手术相比,同时手术增加了总体并发症的相对风险(合并OR:2.00;95%CI:1.10-3.67),然而,它没有增加术后出血的相对风险,术后感染或再次手术。亚组分析显示,在亚洲人群中,同期手术增加了总体并发症的相对风险(分期与并发组:OR:2.41,95%CI:1.51-3.83,I2=0.0%)和术后感染(分期与并发组:OR:2.35,95%CI:1.06-5.21,I2=31.8%)。
未经批准:与分期手术相比,同时手术会增加整体并发症的发生率.然而,两种治疗方法在术后出血方面的差异,术后感染,或者再手术是微不足道的。在亚洲人群中,同时手术与总体术后并发症和术后感染率增加有关。
UNASSIGNED: The combination of cranioplasty and ventriculoperitoneal shunt is a therapeutic strategy for patients with hydrocephalus after decompressive craniectomy (DC). However, the efficacies of simultaneous vs. staged surgery in reducing postoperative complications have not been conclusively determined. This was a meta-analysis of relevant studies to assess whether simultaneous surgery significantly reduces postoperative complication risks, compared to staged surgery.
UNASSIGNED: We systematically searched PubMed, Embase, Cochrane, Web of science databases for studies (published by 11 May 2022) comparing patients undergoing concurrent and staged cranioplasty and ventriculoperitoneal shunt. Our main endpoints were; overall postoperative complications, postoperative bleeding, postoperative infection and reoperation. We assessed the pooled data using a random effects model to compare complication rates using odds ratios (ORs) and 95% confidence intervals (CIs).
UNASSIGNED: Of the 494 identified studies, 12 were included in our analysis (N = 651 participants). Compared to staged surgery, concurrent surgery increased the relative risk for overall complications (pooled OR: 2.00; 95% CI: 1.10-3.67), however, it did not increase the relative risks for postoperative bleeding, postoperative infection or reoperation. Subgroup analysis revealed that in the Asian population, concurrent surgery increased the relative risks for overall complications (staged vs. concurrent group: OR: 2.41, 95% CI: 1.51-3.83, I 2 = 0.0%) and postoperative infections (staged vs. concurrent group: OR: 2.35, 95% CI: 1.06-5.21, I 2 = 31.8%).
UNASSIGNED: Compared to staged surgery, concurrent surgery increases the overall complication rates. However, differences between the two therapeutic approaches in terms of postoperative bleeding, postoperative infection, or reoperation are insignificant. Simultaneous surgery was associated with increased overall post-operative complications and post-operative infection rates in the Asian population.