阴道卵黄囊瘤（YST）是一种罕见的婴儿和儿童恶性生殖细胞肿瘤，自第一例病例报告以来，已经超过50年了。在过去的50年中，治疗策略发生了明显的变化，从根治性手术治疗到保守性手术联合化疗，然后单独进行联合化疗。本研究报告了一个13个月大的女孩的原发性阴道YST病例，该病例通过肿瘤切除联合化疗成功治疗。临床症状,详细介绍了影像学特点和治疗特点,以及术后治疗。迄今为止，随访2年没有局部复发或转移。还进行了文献综述，以调查临床病理特征，该肿瘤的治疗和预后。总的来说,手术联合博来霉素，依托泊苷和卡铂联合化疗可能是阴道YST的有效选择。
A vaginal yolk sac tumor (YST) is a rare malignant germ cell tumor for infants and children, and it has been >50 years since the first case was reported. The treatment strategy has changed markedly in the past 50 years, from radical surgical treatment to conservative surgery combined with chemotherapy, and then to combined chemotherapy alone. The present study reports the case of a primary vaginal YST in a 13-month-old girl that was successfully treated by tumor resection combined with chemotherapy. The clinical symptoms, imaging features and treatment characteristics are described in detail, as well as the postoperative treatment. There was no local recurrence or metastasis for the 2 years of follow-up to date. A literature review was also conducted to investigate the clinicopathological features, treatment and prognosis of this tumor. Overall, surgery combined with bleomycin, etoposide and carboplatin combination chemotherapy can be an effective option for vaginal YST.
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