Ureteral reconstruction

  • 文章类型: Journal Article
    本研究旨在全面概述成人输尿管重建特有的并发症,强调他们的介绍,诊断,输尿管结构疾病的治疗和管理。
    这篇综述涉及对现有文献和案例研究有关输尿管重建的深入分析,重点检查手术后可能出现的并发症的范围。特别注意每个并发症的呈现,所涉及的诊断过程,以及后续的管理策略。
    输尿管重建术可以治疗输尿管狭窄疾病,发病率低;然而,并发症,虽然不常见,会有严重的后果。最显著的并发症包括尿外渗,狭窄复发,尿路感染,筋膜室综合征,有症状的膀胱输尿管反流,和Boari皮瓣坏死。每种并发症都提出了独特的诊断挑战,并需要特定的管理方法。
    输尿管重建术是治疗输尿管狭窄的有效方法。对输尿管重建后患者可能经历的潜在并发症有深刻的了解不仅对于充分咨询患者至关重要,而且还有助于在出现并发症时及时诊断和管理。
    UNASSIGNED: This study aimed to provide a comprehensive overview of the complications unique to ureteral reconstruction in adults, emphasizing their presentation, diagnosis, and management in the treatment of ureteral structure disease.
    UNASSIGNED: This review involves an in-depth analysis of existing literature and case studies pertaining to ureteral reconstruction, with a focus on examining the range of complications that can arise post-surgery. Special attention is given to the presentation of each complication, the diagnostic process involved, and the subsequent management strategies.
    UNASSIGNED: Ureteral reconstruction can treat ureteral stricture disease with low morbidity; however, complications, although uncommon, can have severe consequences. The most notable complications include urinary extravasation, stricture recurrence, urinary tract infections, compartment syndrome, symptomatic vesicoureteral reflux, and Boari flap necrosis. Each complication presents unique diagnostic challenges and requires specific management approaches.
    UNASSIGNED: Ureteral reconstruction is a highly effective treatment for ureteral stricture disease. Having a strong understanding of the potential complications that patients may experience following ureteral reconstruction is not only critical to adequately counsel patients but also facilitate prompt diagnosis and management of complications when they arise.
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  • 文章类型: Journal Article
    襟翼和移植物用于填充死区,输尿管置换,并作为网格替代品。由于机器人能够到达深骨盆,因此手术机器人在泌尿外科重建手术中非常宝贵,它的微创通道,使用吲哚菁绿来识别结构并评估组织灌注和活力的能力,和外科医生的人体工程学。机器人重建可以涉及皮瓣和移植物形式的组织转移,以向因医源性损伤而受损的器官提供形式和功能,创伤,感染,癌症,辐射损伤,或先天性异常。常见的皮瓣和移植物可以容易地适应机器人方法。在这篇文献综述中,我们研究了在重建泌尿外科中使用皮瓣和移植物的机器人。
    通过PubMed搜索预定义术语进行了全面的文献综述。
    重建泌尿外科中的皮瓣和移植物用于插入,输尿管置换,并作为网格替代品。Omental皮瓣用于组织插入,或者提供结构和营养,并且很容易与机器人一起使用。已经描述了腹膜皮瓣的各种机器人应用。腹直肌肌皮瓣是血管化良好的皮瓣,占据死腔并提供结构支持。可以用机器人很容易地收获。乙状结肠表观是骨盆重建的优良皮瓣。龙舌兰皮瓣和阔筋膜移植物耐受性良好,可提供占位组织。Boari皮瓣有助于机器人输尿管重建,尤其是在设置长缺陷时。口腔粘膜非常适合输尿管或膀胱颈重建。直肠粘膜具有良好的耐受性,并且易于通过机器人进行各种尿路重建应用。可以插入阑尾或回肠以修复受损的输尿管。
    各种皮瓣和移植物已适用于机器人重建泌尿外科。随着领域的发展,技术的完善和创新的襟翼和机器人的使用将推动这一领域向前发展。更多研究,尤其是比较研究,需要阐明每个用例最有可能成功且发病率最低的皮瓣和移植物。
    UNASSIGNED: Flaps and grafts are used for filling dead space, ureteral substitution, and as mesh alternatives. The surgical robot is invaluable in urologic reconstructive surgery due to the ability of the robot to reach the deep pelvis, its minimally invasive access, the ability to use indocyanine green to identify structures and assess tissue perfusion and viability, and ergonomics for the surgeon. Robotic reconstruction can involve tissue transfer in the form of flaps and grafts to provide form and function to organs that have been damaged by iatrogenic injuries, trauma, infections, cancer, radiation injury, or congenital abnormalities. Common flaps and grafts can be readily adapted to the robotic approach. In this literature review, we examine the robotic use of flaps and grafts in reconstructive urology.
    UNASSIGNED: A thorough literature review was conducted via a PubMed search for predefined terms.
    UNASSIGNED: Flaps and grafts in reconstructive urology are used for interposition, ureteral substitution, and as mesh alternatives. Omental flaps are used for tissue interposition, or to provide structure and nutrients, and are easily employed with the robot. Various robotic applications of peritoneal flaps have been described. Vascular rectus abdominis musculocutaneous flaps are well-vascularized flaps that occupy dead space and provide structural support, which can be harvested readily with the robot. Sigmoid epiploica are an excellent flap for pelvic reconstruction. Gracilis flaps and fascia lata grafts are well-tolerated and provide space occupying tissue. Boari flaps aid in robotic ureteral reconstruction, especially in the setting of long defects. Oral mucosa is excellent for ureteral or bladder neck reconstruction. Rectal mucosa is well-tolerated and easy to harvest robotically for a variety of urinary tract reconstructive applications. The appendix or ileum can be interposed for repair of damaged ureters.
    UNASSIGNED: Various flaps and grafts have been adapted for robotic reconstructive urology. As the field develops, refinement of techniques and innovation in flaps and employment of the robot will propel this field forward. More studies, especially comparative studies, are needed to elucidate the flaps and grafts that are most likely to be successful with the least morbidity for each use case.
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  • 文章类型: Journal Article
    目的:机器人方法在重建泌尿外科中越来越受欢迎。重建外科医生通常使用皮瓣和移植物来消除死腔,包括组织插入或作为网状物的替代方法来解决下尿路功能障碍。机器人方法的优点是切口疼痛少,在深骨盆中出色的可视化,和改进的外科医生人体工程学。在这篇文献综述中,我们描述了用于下尿路机器人重建泌尿外科的皮瓣和移植物,作为这些技术的历书。
    结果:Omental,腹膜,垂直腹直肌肌皮(VRAM),乙状结肠表观,gracilis皮瓣,和Alloderm™已被报道用于瘘管修复期间的组织插入。Fascialata已被描述为机器人sacrocolpopexy的网状替代品。除了提供干预,皮瓣支持天然组织愈合和血液供应。移植物易于使用,患者发病率低,而是依赖于受体部位的血液供应。机器人重建是一个新兴的领域,需要更多的研究来确定每个皮瓣和移植物的最佳用途,以及最大化结果和最小化发病率的策略。
    OBJECTIVE: The robotic approach is increasingly popular in reconstructive urology. Reconstructive surgeons have commonly used flaps and grafts for obliterating dead space including tissue interposition or as an alternative to mesh in addressing lower urinary tract dysfunction. Advantages of the robotic approach are less incisional pain, excellent visualization in the deep pelvis, and improved surgeon ergonomics. In this literature review, we describe flaps and grafts used in lower urinary tract robotic reconstructive urology, serving as an almanac for these techniques.
    RESULTS: Omental, peritoneal, vertical rectus abdominis musculocutaneous (VRAM), sigmoid epiploica, gracilis flaps, and Alloderm™ have been reported for tissue interposition during fistula repair. Fascia lata has been described as a mesh alternative for robotic sacrocolpopexy. Besides providing interposition, flaps support native tissue healing and blood supply. Grafts are easy to use with low patient morbidity, but rely on the blood supply at the recipient site. Robotic reconstruction is an emerging field, and more studies are needed to define the best uses for each flap and graft as well as strategies to maximize outcomes and minimize morbidity.
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  • 文章类型: Journal Article
    目的:介绍我们的腹腔镜回肠输尿管置换术(LIUR)队列的长期结果,包括更复杂的腹腔镜回肠造口术。材料和方法:我们收集了接受LIUR的患者的记录。随访包括化学概况和尿液培养。影像学包括肾脏超声检查,排泄性尿路造影,膀胱造影,和计算机断层摄影或磁共振尿路造影。结果:共纳入102例患者。左狭窄位置(46.1%),右(39.2%),或双边(14.7%)。没有进行开放转化。74例患者(72.5%)接受了输尿管单元的全部切除。平均手术时间为289.4(120-680)分钟。估计失血量为185.2(10-400)mL。3例患者术中出现并发症,15例术后早期并发症。术后平均住院时间为12.2(7-35)天。平均随访时间为37.7(12-162)个月。大多数患者随访顺利(88%),7例患者出现2级晚期并发症。结论:在广泛的输尿管病变的情况下,体内腹腔镜回肠输尿管置换术可提供最佳的长期结果和低并发症发生率。在少数患有长近端输尿管狭窄和肾内骨盆的患者中,回肠吻合术是可行的选择。
    UNASSIGNED: To present long-term results of our laparoscopic intracorporeal ileal ureter replacement (LIUR) cohort, including more complex cases of laparoscopic ileocalycostomy.
    UNASSIGNED: We collected records of patients undergoing LIUR. Follow-up included a chemical profile and urine cultures. Imaging consisted of renal ultrasonography, excretory urography, cystography, and computer tomographic or magnetic resonance urography.
    UNASSIGNED: One hundred and two patients were included. Stricture location was left (46.1%), right (39.2%), or bilateral (14.7%). No open conversion was performed. Seventy-four patients (72.5%) underwent a total ureteral unit removal. The mean operative time was 289.4 (120 - 680) minutes. The estimated blood loss was 185.2 (10-400) mL. Three patients had intraoperative complications, and fifteen had early postoperative complications. The mean postoperative hospital stay was 12.2 (7-35) days. The mean follow-up duration period was 37.7 (12-162) months. Most patients\' follow-up was uneventful (88%), and seven patients presented with Grade 2 late complications.
    UNASSIGNED: Intracorporeal laparoscopic ileal ureteral replacement in cases of extensive ureteral lesions offers optimal long-term outcomes and a low complication rate. Ileocalycostomy constitutes a viable option in the small group of patients with long proximal ureteral strictures and intrarenal pelvis.
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  • 文章类型: Journal Article
    输尿管上段狭窄是一种相对罕见但在临床实践中越来越多地遇到的疾病。虽然简单的狭窄通常可以通过腔内治疗或手术重建来解决,复杂的输尿管上段狭窄带来了挑战,特别是在肾盂输尿管连接部梗阻(UPJO)或肾盂周围纤维化和先前手术导致的瘢痕形成的患者中。这些病例对传统的腔内和输尿管重建治疗提出了困难。对许多临床外科医生来说是一个重大问题。我们的研究涉及对输尿管造口术(UC)的现有文献的全面搜索和综合分析。文献表明UC是治疗输尿管狭窄安全有效的方法。通过切除肾下极实质,在肾盏和输尿管粘膜之间实现粘膜吻合是可能的,导致恢复正常的尿排泄。该技术已成为治疗复杂的上输尿管狭窄的替代方法。然而,开放手术和微创手术之间缺乏直接的比较研究。我们的发现揭示了相关审查文件的稀缺性,大多数病例报告或回顾性研究是在小样本量的单个中心进行的。因此,进行大规模是至关重要的,多中心前瞻性研究和长期随访以验证UC的长期疗效。本文回顾了UC的发展历史,重点对其适应症进行了全面的讨论,外科技术,和并发症。
    Upper ureteral stricture is a relatively rare but increasingly encountered condition in clinical practice. While simple stricture can often be addressed through endoluminal treatment or surgical reconstruction, complex upper ureteral stricture poses challenges, particularly in patients with ureteropelvic junction obstruction (UPJO) or perirenal pelvic fibrosis and scarring resulting from previous surgeries. These cases present difficulties for traditional endoluminal and ureteral reconstruction treatments, posing a significant problem for many clinical surgeons. Our study involved a thorough search and comprehensive analysis of the existing literature on Ureterocalicostomy (UC). The literature indicates that UC is a safe and effective treatment for ureteral stenosis. By resecting the renal lower pole parenchyma, it is possible to achieve mucosal anastomosis between the calyceal and ureteral mucosa, leading to the restoration of normal urinary excretion. This technique has emerged as an alternative for treating complex upper ureteral strictures. However, there is a lack of direct comparative studies between open surgery and minimally invasive surgery. Our findings revealed a scarcity of relevant review documents, with most being case reports or retrospective studies conducted in single centers with small sample sizes. Therefore, it is crucial to conduct large-scale, multicenter prospective studies and long-term follow-up to validate the long-term efficacy of UC. This article reviews the development history of UC and focuses on a comprehensive discussion of its indications, surgical techniques, and complications.
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  • 文章类型: Journal Article
    目的:确定输尿管远端切除长度对膀胱切除术和尿流改道后输尿管-肠吻合口良性狭窄(UEAS)形成风险的影响。
    方法:分析了2015年至2022年接受膀胱切除术和尿流改道的患者数据库。输尿管远端切除送去最后病理。从病理报告收集切除的输尿管的长度。肾脏闪烁显像证实良性UEAS,顺行性肾图,或内窥镜评估。使用T检验评估狭窄形成与临床参数之间的关系,卡方检验,和多变量分析。
    结果:总共366例患者接受了膀胱切除术和尿流改道。在队列中,35例(9.5%)患者发生UEAS。狭窄形成的中位时间为12.5个月(IQR4-30)。在711例输尿管-肠吻合术中,40(5.6%)最终形成了UEAS。在未形成UEAS的输尿管吻合术中,输尿管远端切除术的中位数明显更长(2.3cmvs.1.65厘米,p=0.028)。多变量logistic回归调整手术方式,先前的辐射,输尿管侧,和尿流改道类型表明,较长的输尿管远端切除与UEAS形成的几率成反比(OR0.73,95%CI0.58-0.92)。多变量Cox回归分析显示,输尿管远端切除长度与狭窄形成时间呈负相关(HR0.78,95%CI0.62-0.98)。
    结论:良性UIA狭窄的病因是多因素的。血管妥协是一个关键的假设。我们发现,膀胱切除术患者的输尿管远端切除时间较长(因此输尿管较短)与狭窄形成的风险显着降低相关。
    To identify the impact of length of distal ureteral resection on the risk of benign uretero-enteric anastomotic stricture (UEAS) formation following cystectomy and urinary diversion.
    A database of patients who underwent cystectomy and urinary diversion from 2015 to 2022 was analyzed. Distal ureteral resections were sent for final pathology. The length of resected ureter was collected from pathology reports. Benign UEAS were confirmed with renal scintigraphy, antegrade nephrostogram, or endoscopic evaluation. The relationship between stricture formation and clinical parameters were assessed using T-tests, chi-square tests, and multivariable analysis.
    A total of 366 patients underwent cystectomy and urinary diversion. Of the cohort, 35 (9.5%) patients developed UEAS. Median time to stricture formation was 12.5months (IQR 4-30). Of the 711 uretero-enteric anastomoses, 40 (5.6%) ultimately formed a UEAS. Median distal ureteral resection was significantly longer among ureteral anastomoses which did not form a UEAS (2.3 cm vs 1.65 cm, P = .028). Multivariable logistic regression adjusting for surgical approach, prior radiation, ureteral side, and urinary diversion type demonstrated that longer distal ureteral resections were inversely associated with odds of UEAS formation (OR 0.73, 95% CI 0.58-0.92). Multivariable Cox regression analysis similarly showed that length of distal ureteral resection was inversely associated with time to stricture formation (HR 0.78, 95% CI 0.62-0.98).
    The etiology of benign UIA strictures is multifactorial. Vascular compromise is a critical hypothesis. We found that longer distal ureteral resections (and thus shorter ureters) were associated with a significantly lower risk of stricture formation in cystectomy patients.
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  • 文章类型: Case Reports
    输尿管缺损可以使用取决于缺损的长度和位置的多种不同技术来修复。这里我们描述了一个例子,使用阑尾间置移植物成功重建了输尿管上段缺损。一名60岁的女性患者接受了右侧腹膜后平滑肌肉瘤的切除术,该肉瘤包裹了整个上输尿管并阻塞了右肾。肿块被整体切除,留下11厘米的输尿管缺损。通过阑尾间位移植物成功重建了缺损。阑尾插入移植物是成人肿瘤切除术后输尿管重建的可行且有效的方法。我们描述了优化输尿管重建成功的各种技术方面。
    Ureteral defects can be repaired using a variety of different techniques that depend on the length and position of the defect. Here we describe a case where a long, upper-ureteral defect was successfully reconstructed using an appendiceal interposition graft. A 60-year-old female patient underwent resection of a right-sided retroperitoneal leiomyosarcoma that was encasing the entire upper ureter and obstructing the right kidney. The mass was resected en bloc, leaving behind an 11 cm ureteral defect. The defect was successfully reconstructed with an appendiceal interposition graft. Appendiceal interposition grafts are a feasible and effective approach for ureteral reconstruction in adults following oncologic resection. We describe various technical aspects that optimize the success of ureteral reconstruction.
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  • 文章类型: Case Reports
    在其他地方两次失败的左输尿管肾盂交界处(UPJ)阻塞修复后,一名11岁男孩被转介接受进一步治疗6厘米长的严重狭窄输尿管。降结肠(TDC)的锥形段已成功用于输尿管重建。UPJ通过左侧切口暴露。切除狭窄段;两端出现严重发炎和增厚。需要组织插入,并通过切开与切除的输尿管相邻的腹膜以将降结肠动员到腹膜后空间来进行TDC输尿管成形术。为了准备TDC,分离出一个8厘米长的血管完整的结肠段,锥形,并使用14-Fr导管作为临时支架缝合成漏斗形。结肠造口术后,结肠回到腹腔,小心地关闭腹膜以防止血管受损,TDC用间断的可吸收缝线与输尿管和肾盏吻合。放置双J支架(DJS)和经皮肾造瘘管。术后恢复顺利。在确认通过输尿管-TDC和花萼-TDC吻合术两者的顺利尿液流动之后,在第50天移除DJS。术后68天进行的利尿肾图检查通畅。经过12个月的随访,患者目前情况良好。这似乎是TDC被用来创建一个漏斗形段来重建一个长的,严重狭窄的输尿管。TDC比重新管状结肠更简单,但需要监测术后粘液相关并发症和恶性转化。
    An 11-year-old boy was referred for further management of a 6-cm-long grossly stenosed ureter following two failed left ureteropelvic junction (UPJ) obstruction repairs elsewhere. A tapered segment of the descending colon (TDC) was used successfully for ureteral reconstruction. The UPJ was exposed through a left flank incision. The stenosed segment was excised; both ends appeared severely inflamed and thickened. Tissue interposition was required and ureteroplasty with a TDC was performed by incising the peritoneum adjacent to the excised ureter to mobilize the descending colon to the retroperitoneal space. To prepare the TDC, an 8-cm segment of the colon with intact blood vessels was isolated, tapered, and sutured into a funnel shape using a 14-Fr catheter as a temporary stent. After colocolostomy, the colon was returned to the abdominal cavity, the peritoneum was closed carefully to prevent vascular compromise, and the TDC was anastomosed to the ureter and renal calyx with interrupted absorbable sutures. A double J stent (DJS) and percutaneous nephrostomy tube were placed. Postoperative recovery was uneventful. The DJS was removed on day 50 after confirming smooth urine flow through both the ureter-TDC and calyx-TDC anastomoses. Diuretic renography performed 68 days postoperatively was unobstructed. The patient is currently well after 12 months follow-up. This would appear to be the first report of a TDC being used to create a funnel-shaped segment to reconstruct a long, grossly stenosed ureter. The TDC is simpler than the re-tubularizing colon but requires monitoring for postoperative mucus-related complications and malignant transformation.
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  • 文章类型: Journal Article
    放射治疗是盆腔恶性肿瘤的常见治疗方式。虽然它可以有效控制癌症,下游影响可以在治疗后几个月到几年出现,使患者具有显著的发病率。在泌尿科,一个特别困难的辐射后后果是尿路狭窄,尿道中的任何一个,膀胱颈,或输尿管。在这次审查中,我们将讨论放射性损伤的机制和治疗这些潜在的破坏性尿路后遗症的选择。
    Radiation is a common treatment modality for pelvic malignancies. While it can be effective at cancer control, downstream effects can manifest months to years after treatment, leaving patients with significant morbidity. Within urology, a particularly difficult post-radiation consequence is urinary tract stricture, either of the urethra, bladder neck, or ureter. In this review, we will discuss the mechanism of radiation damage and treatment options for these potentially devastating urinary sequelae.
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  • 文章类型: Journal Article
    背景:关于长段或全输尿管停药的重建尚未达成明确共识。在这里,我们介绍了使用Yang-Monti技术进行输尿管全重建的经验。
    方法:本研究是对接受Yang-Monti回肠全输尿管重建术(从肾盂输尿管交界处[UPJ]到输尿管膀胱交界处)患者的单中心回顾性研究。收集患者基线特征的数据,狭窄的病因,损伤和手术修复之间的时间间隔,术前/术后血清肌酐,估计肾小球滤过率(eGFR),分裂肾功能,入院和随访期间的并发症,以及JJ管和肾造瘘管的留置时间,如果提交。
    结果:2010-2020年我院行Yang-Monti回肠输尿管重建术7例。其中一名患者接受了一次性双侧输尿管修复。放射治疗相关的纤维化和脱套损伤是输尿管损伤最常见的病因。输尿管损伤至手术的中位间隔为8个月。中位随访时间为36.7个月。平均手术时间11.4h,平均失血量为273ml。术后,血清肌酐无显著差异,eGFR,或分裂的肾功能。至于术后并发症,2例患者出现肠梗阻,接受保守治疗.一名患者患有UPJ狭窄,在11个月后重新吻合手术后解决。未报告代谢性酸中毒或电解质失衡。
    结论:我们发现,使用Yang-Monti原理的回肠置换治疗输尿管全失是有效且持久的。这是最大的队列研究,随访超过2年。
    BACKGROUND: No clear consensus has been reached on the reconstruction of long-segment or total ureter discontinuation. Here we present our experience using the Yang-Monti technique in total ureter reconstruction.
    METHODS: This study was a single-center retrospective study of patients who underwent Yang-Monti ileal whole ureter reconstruction (from the ureteropelvic junction[UPJ] to the ureterovesical junction). Data were collected on patients\' baseline characteristics, stricture etiology, the time interval between insult and surgical repair, pre/postoperative serum creatinine, estimated glomerular filtration rate (eGFR), split renal function, complications during admission and follow-ups, and the indwelling durations of JJ tubes and nephrostomy tubes, if presented.
    RESULTS: Seven patients underwent Yang-Monti ileal ureter reconstruction in 2010-2020 at our hospital. One of the patients underwent single-session bilateral ureter repair. Radiation therapy-related fibrosis and degloving injury were the most common etiologies for ureter injury. The median interval between ureter insult and operation was 8 months. The median follow-up was 36.7 months. The average operation time was 11.4 h, and the average blood loss was 273 ml. Postoperatively, no significant differences were found in serum creatinine, eGFR, or split renal function. As for postoperative complications, two patients experienced ileus and were treated conservatively. One patient had UPJ stenosis, which resolved after re-anastomosis surgery 11 months later. Metabolic acidosis or electrolyte imbalance was not reported.
    CONCLUSIONS: We found that ileal replacement of total ureteral loss using the Yang-Monti principle is effective and durable. This is the largest cohort study conducted with more than 2 years of follow-up.
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