最近,抗生素的广泛滥用和过度使用导致的耐药性对人类健康构成了巨大威胁。学者们对不同类型环境中抗生素抗性细菌和抗生素抗性基因(ARGs)的影响进行了大量研究。气溶胶不仅是ARGs的潜在储库,也是ARGs在环境中传播的重要途径。然而,对其来源进行系统总结,传输,人体暴露,缺乏健康风险。这篇综述集中在四种典型的气溶胶研究场所:人类功能性居住场所,农场,城市污水处理厂,和医院。的来源,传输路线,人体暴露,并对这四个典型地点气溶胶中ARGs的健康风险进行了综述。为气溶胶中ARGs的防治提供参考。
Recently, drug resistance resulted from the extensive abuse and over-use of antibiotics has posed a great threat to human health. Scholars have conducted numerous studies on the impacts of antibiotic resistant bacteria and antibiotic resistance genes (ARGs) in different types of environments. Aerosol is not only a potential reservoir for ARGs, but also an important route for transmission of ARGs in the environment. However, a systematic summary of its sources, transmission, human exposure, and health risks is lacking. This review focused on four types of typical sites for aerosol research: human functional living places, farms, urban wastewater treatment plants, and hospitals. The sources, transmission routes, human exposure, and health risks of ARGs in the aerosol of these four typical sites were reviewed. This article also provides a reference for prevention and control of ARGs in aerosols.