未经评估:GLOBOCAN2020和全球疾病负担(GBD)2019是两个最成熟的全球在线癌症数据库。重要的是要检查两个平台之间的差异,试图解释这些差异,并评估数据的质量。唇癌和口腔癌(LOC)存在明显差异,我们试图通过对十个国家的极端差异进行详细分析来解释这些差异。
未经评估:LOC的年龄标准化发病率(ASIR)来自GLOBOCAN2020和GBD2019。选择了倍数差异最大和最小的五个国家。然后对PubMed和Embase电子数据库进行系统搜索,以确定报告2015年至2022年选定国家LOC发生率的出版物。具体来说,对文章的数据源进行了检查和评估。
未经评估:对于LOC,在巴布亚新几内亚发现了最大的差异,越南,中国,巴基斯坦,印度尼西亚(A组)。相比之下,美利坚合众国(美国),巴西,法国,德国,和印度(B组)在两个数据库之间的差异最小。
UNASSIGNED:当GLOBOCAN和GBD无法从国家或地方癌症登记处获得高质量或可访问的LOC数据时,这并不奇怪,与A组一样,这两个在线数据库之间会有差异。相比之下,在GLOBOCAN和GBD之间只有微小的差异,与B组一样,假定是由于那些拥有完善的癌症登记处和医疗保健管理系统的国家,文献更加一致。此外,许多研究将嘴唇和口腔与咽部分组,并将输出分为“口腔和口咽癌”或“口腔和咽癌”。这些分类缺乏亚位点的准确性,并且没有意识到口腔癌和口咽癌具有完全不同的病因。病因,预后,和治疗结果。
UNASSIGNED:这项研究没有从任何公共资助机构获得具体的资助或资助,商业,或者非营利部门,作者没有获得研究的财政支持,作者身份,和/或本文的出版。
UNASSIGNED: GLOBOCAN 2020 and Global Burden of Disease (GBD) 2019 are the two most established global online cancer databases. It is important to examine the differences between the two platforms, to attempt to explain these differences, and to appraise the quality of the data. There are stark differences for lip and oral cancers (LOC) and we attempt to explain these by detailed analysis of ten countries at the extremes of differences.
UNASSIGNED: Age-standardised incidence rates (ASIR) of LOC were obtained from GLOBOCAN 2020 and GBD 2019. Five countries with the greatest and smallest fold differences were selected. A systematic search of PubMed and Embase electronic databases was then performed to identify publications reporting the incidence of LOC in the selected countries between 2015 and 2022. Specifically, data sources of the articles were examined and evaluated.
UNASSIGNED: For LOC, greatest differences were found in Papua New Guinea, Vietnam, China, Pakistan, and Indonesia (group A). In contrast, the United States of America (USA), Brazil, France, Germany, and India (group B) had the least differences between the two databases.
UNASSIGNED: It is not surprising that when GLOBOCAN and GBD could not obtain high-quality or accessible LOC data from national or local cancer registries, as in group A, discrepancies would be seen between the two online databases. In contrast, where only minor differences were seen between GLOBOCAN and GBD, as in group B, presumptively due to those countries having well-established cancer registries and healthcare administrative systems, the literature is more consistent. Moreover, many studies have grouped lip and oral cavity with pharynx and categorised outputs as \"oral and oropharyngeal cancer\" or \"oral cavity and pharynx cancer\". Those categorisations lacked subsite accuracy and failed to realise that oral cancer and oropharyngeal cancer have completely different etiological factors, pathogeneses, prognosis, and treatment outcomes.
UNASSIGNED: This research received no specific grant or funding from any funding agency in the public, commercial, or not-for-profit sectors, and the authors received no financial support for the research, authorship, and/or publication of this article.