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  • 文章类型: Journal Article
    耐甲氧西林金黄色葡萄球菌(MRSA)是医院和社区感染的常见原因,在某些情况下严重和难以治疗。此外,有一些MRSA菌株与产食动物特别相关。出于这个原因,近年来,人们特别关注动物源性食品在这种微生物感染中的作用。为了了解肉类和肉类产品中MRSA的患病率和类型,自2001年以来,对有关该主题的工作进行了审查,总共259种出版物,185个与零售店的肉类样本有关,74个与农场收集的动物来源样本有关,屠宰场和肉类加工设施。在零售商店的84.3%的报告(185个中的156个)和农场的86.5%的报告(74个中的64个)中检测到MRSA菌株,屠宰场和肉类加工设施,尽管在大多数研究中,这种微生物在不到20%的零售店样本中检测到,来自农场的人不到10%,屠宰场和肉类加工设施。最常被MRSA污染的肉和肉制品是猪肉和鸡肉。除了mecA基因,考虑到mecB和mecC基因是至关重要的,以避免将菌株错误识别为MSSA(甲氧西林敏感的金黄色葡萄球菌)。用于测定MRSA的方法多种多样,这凸显了开发用于研究食品中这种微生物的标准化方案的必要性。
    Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent cause of nosocomial and community infections, in some cases severe and difficult to treat. In addition, there are strains of MRSA that are specifically associated with food-producing animals. For this reason, in recent years special attention has been paid to the role played by foodstuffs of animal origin in infections by this microorganism. With the aim of gaining knowledge on the prevalence and types of MRSA in meat and meat products, a review was undertaken of work published on this topic since 2001, a total of 259 publications, 185 relating to meat samples from retail outlets and 74 to samples of animal origin collected in farms, slaughterhouses and meat processing facilities. Strains of MRSA were detected in 84.3% reports (156 out of 185) from retail outlets and 86.5% reports (64 out of 74) from farms, slaughterhouses and meat processing facilities, although in most of the research this microorganism was detected in under 20% of samples from retail outlets, and under 10% in those from farms, slaughterhouses and meat processing facilities. The meat and meat products most often contaminated with MRSA were pork and chicken. In addition to the mecA gene, it is crucial to take into consideration the mecB and mecC genes, so as to avoid misidentification of strains as MSSA (methicillin-susceptible Staphylococcus aureus). The great variety of methods used for the determination of MRSA highlights the need to develop a standardized protocol for the study of this microorganism in foods.
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  • 文章类型: Journal Article
    目的:在现有文献中,已经报道了小脑胸肌(PMi)肌肉的各种插入变异和分类。然而,关于PMi肌肉下起源变化的信息有限,缺乏一定的分类。
    方法:在成年男性的常规尸体解剖中,确定了双侧PMi肌肉起源的变化。PMi的形态测量使用ImageJ软件进行,PMi的异常起源模式被分为特定类型。PMi肌肉表现出双侧变化。在右边,PMi显示包含内侧和外侧纤维的双歧结构。左PMi起源于第4至第6肋的上外侧边缘,并终止于喙突的前上表面。合并前右侧内侧纤维长度为5.67±0.04cm,右侧纤维为6.68±0.05cm。两根纤维之间的距离测量为0.43cm,长度为3.33±0.02厘米。延伸至第6肋骨的肌纤维的长度和直径分别为2.63±0.01cm和0.46cm,分别。
    结论:由发育过程中的损伤引起的PMi的潜在变化可能偶尔表现为无症状状况或易受肩关节撞击的个体。肩袖功能障碍,肩关节相关疾病,和功能障碍。因此,在手术计划中考虑了对这种变化的仔细注意。
    OBJECTIVE: In the existing literature, various insertion variations and classifications for the Pectoralis Minor (PMi) muscle have been reported. However, there is limited information on inferior origin variations of the PMi muscles and a certain classification is lacking.
    METHODS: During routine cadaver dissection of an adult male, variations in the origin of the bilateral PMi muscles were identified. Morphometric measurements of the PMi were conducted using ImageJ software, and the unusual origin patterns of the PMi were categorized into specific types. The PMi muscle demonstrated a bilateral variations. On the right side, the PMi displays a bifid structure comprising medial and lateral fibers. The left PMi originate from the superolateral margins of the 4th to 6th costae and terminate at the anterosuperior surface of the coracoid process. The length of the right medial fiber before merging was 5.67 ± 0.04 cm, while that of the right lateral fiber was 6.68 ± 0.05 cm. The distance between the two fibers was measured as 0.43 cm, with a length of 3.33 ± 0.02 cm. The length and diameter of the muscle fibers extending to the 6th costa were 2.63 ± 0.01 cm and 0.46 cm, respectively.
    CONCLUSIONS: Potential variations in PMi arising from impairment during development may occasionally manifest as asymptomatic conditions or predispose individuals to shoulder impingement, rotator cuff dysfunction, shoulder-related disorders, and functional impairments. Therefore, careful attention to this variation is considered in surgical planning.
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  • 文章类型: Journal Article
    牙釉质发育不全(EH)是一种定性缺陷,它可以对口腔健康产生重大影响。这项研究的目的是评估阿尔巴尼亚城市地区牙釉质发育不全的患病率。
    方法:总共,在地拉那的五所学校中随机选择了234名8-12岁的男女儿童,阿尔巴尼亚。他们接受了口内检查。诊断标准符合在雅典举行的MIH欧洲会议,2003年,外国直接投资。使用问卷检索病史,并记录从临床检查中获得的数据.
    结果:牙釉质发育不全的患病率为12.8%。最常见的釉质发育不全是轻度类型(58.62%)。下颌第一磨牙的釉质发育不全患病率最高(19.5%),上颌和前磨牙受影响最小(2.3%)。在这项研究中,医学故事对牙釉质发育不全没有显着影响。
    结论:牙釉质发育不全的患病率仍然很高,为12.8%。有趣的是,两种性别的釉质发育不全的特征是一致的,它们之间没有相关性。轻度牙釉质发育不全的主要发生强调了在学校实施口腔卫生策略以减轻其进展的重要性。
    Enamel hypoplasia (EH) is a qualitative defect, and it can have a significant impact on oral health. The aim of this study was to evaluate the prevalence of enamel hypoplasia in urban area in Albania.
    METHODS: In total, 234 children of both sexes aged 8-12 years old were randomly selected in five schools in Tirana, Albania. They underwent an intra-oral examination. Diagnostic criteria were in accordance with a European meeting on MIH held in Athens, 2003, and the FDI. Medical history was retrieved using questionnaires, and data obtained from clinical examination were recorded.
    RESULTS: The prevalence of enamel hypoplasia was 12.8%. The most commonly occurring enamel hypoplasia was the mild type (58.62%). The mandibular first molar showed the highest prevalence of enamel hypoplasia (19.5%), and the maxillary canines and premolars were the least affected (2.3%). In this study, medical story did not have a significant effect on enamel hypoplasia.
    CONCLUSIONS: The prevalence of enamel hypoplasia remains high at 12.8%. Interestingly, the features of enamel hypoplasia were consistent across both sexes, with no correlation found between them. The predominant occurrence of mild enamel hypoplasia underscores the importance of implementing oral hygiene strategies in schools to mitigate its progression.
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  • 文章类型: Journal Article
    背景:血管水肿(AE)表现为间歇性,局部化,皮下和/或粘膜下组织的自限性肿胀。AE是异质的,可以是遗传的或后天的,只发生一次或反复发生,有或没有风头,由于肥大细胞介体,缓激肽或其他机制。目前,使用不同的分类系统,很难比较研究结果,发展多中心协作,并协调AE患者的治疗。
    目的:为了就定义达成共识,首字母缩略词,命名法,和血管性水肿的分类(DANCE)。
    方法:该倡议涉及来自35个国家的91名专家,得到了53名科学、医学社会,患者组织。在16个月的时间内(2021年6月至2022年11月),使用Delphi流程通过在线讨论和投票达成了共识。
    结果:DANCE倡议在定义上达成了国际共识,AE的分类和术语。新的共识分类具有AE的五种类型和内生型以及缩写和首字母缩写词的统一词汇。
    结论:DANCE分类补充了当前临床指南和关于AE诊断和治疗的专家共识建议。DANCE不能取代当前的临床指南和专家共识算法,并且不应以影响医生使用合理的临床判断开具的药物报销的方式进行误解。我们预计新的AE分类法和命名法将协调和促进AE研究和临床研究,从而改善患者护理。
    BACKGROUND: Angioedema (AE) manifests with intermittent, localized, self-limiting swelling of the subcutaneous and/or submucosal tissue. AE is heterogeneous, can be hereditary or acquired, may occur only once or be recurrent, may exhibit wheals or not, and may be due to mast cell mediators, bradykinin, or other mechanisms. Several different taxonomic systems are currently used, making it difficult to compare the results of studies, develop multicenter collaboration, and harmonize AE treatment.
    OBJECTIVE: We developed a consensus on the definition, acronyms, nomenclature, and classification of AE (DANCE).
    METHODS: The initiative involved 91 experts from 35 countries and was endorsed by 53 scientific and medical societies, and patient organizations. A consensus was reached by online discussion and voting using the Delphi process over a period of 16 months (June 2021 to November 2022).
    RESULTS: The DANCE initiative resulted in an international consensus on the definition, classification, and terminology of AE. The new consensus classification features 5 types and endotypes of AE and a harmonized vocabulary of abbreviations/acronyms.
    CONCLUSIONS: The DANCE classification complements current clinical guidelines and expert consensus recommendations on the diagnostic assessment and treatment of AE. DANCE does not replace current clinical guidelines, and expert consensus algorithms and should not be misconstrued in a way that affects reimbursement of medicines prescribed by physicians using sound clinical judgment. We anticipate that this new AE taxonomy and nomenclature will harmonize and facilitate AE research and clinical studies, thereby improving patient care.
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  • 文章类型: Journal Article
    纳米技术是一个迷人的当代技术,由于其广泛的潜在应用。这项研究强调纳米材料,尺寸<100nm的物质,提供比粗颗粒更好的质量。纳米颗粒与常规药物递送方法相比具有若干优势,包括增强的生物利用度和较大的表面积,因为它们的粒径较小。这些特征使得纳米颗粒成为可行的临床候选物。控释药物递送系统和靶向药物递送系统严重依赖于纳米颗粒。由于传统的给药方式无法实现靶向给药,导致毒性,低生物利用度,治疗效果不佳,等等,这些药物纳米颗粒在所有这些领域都很出色。研究人员已经对开发诸如niosomes之类的药物递送系统感兴趣,Bilosomes,和树枝状聚合物。纳米乳剂是这些技术之一;纳米乳剂在药效学和药代动力学方面优于传统乳剂。纳米乳液有效地超越了标准乳液的约束,主要是通过提供增强的生物利用度,降低毒性,改善吸收,以及用于靶向药物递送或控释药物递送系统的潜力。这项特别的工作探索了纳米乳液的几个方面,包括他们的选民,分类,准备技术,评估标准,商业应用,和未来的前景。
    Nanotechnology is a captivating contemporary technology owing to its extensive range of potential applications. This study emphasizes nanomaterials, substances with a size <100 nm, offering better qualities than coarse particles. Nanoparticles have several advantages compared with conventional drug delivery methods, including enhanced bioavailability and a larger surface area because of their smaller particle size. These characteristics make the nanoparticles a viable clinical candidate. Controlled-release drug delivery systems and targeted drug delivery systems rely heavily on nanoparticles. Because traditional drug delivery methods fail to achieve targeted drug delivery, resulting in toxicity, low bioavailability, poor therapeutic outcomes, and so on, these drug nanoparticles excel in all these areas. Researchers are already interested in developing drug delivery systems such as niosomes, bilosomes, and dendrimers. Nanoemulsion is one of these technologies; nanoemulsions outperform traditional emulsions in terms of pharmacodynamics and pharmacokinetics. Nanoemulsion effectively surpasses the constraints of standard emulsions, primarily by offering enhanced bioavailability, reduced toxicity, improved absorption, and the potential to be used in targeted drug delivery or controlled-release drug delivery systems. This particular work explores several aspects of nanoemulsions, including their constituents, classification, techniques for preparation, criteria for assessment, commercial applications, and future prospects.
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  • 文章类型: Journal Article
    实时数据收集,分析,这种信息和通信技术系统使反应成为可能。它也使数据存储成为可能。这是一个很好的举措,因为它增强了任何城市高效运营所必需的管理和运营服务。“智慧城市”背后的想法是,信息和通信技术(ICT)需要被纳入城市的日常活动中,以便收集,分析,并实时存储大量数据。这很有帮助,因为它使城市地区的管理和治理变得更加容易。“无人机”或“无人飞行器”(无人机),可以进行通常需要人类驾驶员的活动,作为一个例子。无人机可以用来整合地理空间数据,管理流量,留意物体,作为智能城市结构的一部分,在紧急情况下提供帮助。本研究着眼于概念中部署无人机的利弊,发展,和智慧城市的管理。本文介绍了在设计中部署无人机的重要性和优势,发展,并在智慧城市中维护。本文概述了无人机的使用类型,应用程序,和挑战。此外,我们提出了区块链方法来解决智能研究主题中无人机的给定问题,并提出了改善智能城市无人机安全性和隐私性的建议。此外,我们提出了区块链方法来解决智慧城市中无人机的给定问题。研究员和研究生是我们文章的听众。
    Real-time data gathering, analysis, and reaction are made possible by this information and communication technology system. Data storage is also made possible by it. This is a good move since it enhances the administration and operation services essential to any city\'s efficient operation. The idea behind \"smart cities\" is that information and communication technology (ICTs) need to be included in a city\'s routine activities in order to gather, analyze, and store enormous amounts of data in real-time. This is helpful since it makes managing and governing urban areas easier. The \"drone\" or \"uncrewed aerial vehicle\" (UAV), which can carry out activities that ordinarily call for a human driver, serves as an example of this. UAVs could be used to integrate geospatial data, manage traffic, keep an eye on objects, and help in an emergency as part of a smart urban fabric. This study looks at the benefits and drawbacks of deploying UAVs in the conception, development, and management of smart cities. This article describes the importance and advantages of deploying UAVs in designing, developing, and maintaining in smart cities. This article overviews UAV uses types, applications, and challenges. Furthermore, we presented blockchain approaches for addressing the given problems for UAVs in smart research topics and recommendations for improving the security and privacy of UAVs in smart cities. Furthermore, we presented Blockchain approaches for addressing the given problems for UAVs in smart cities. Researcher and graduate students are audience of our article.
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  • 文章类型: Journal Article
    在漫长的进化过程中,植物已经发展了自我保护机制,比如留下种子,落叶,越来越多的荆棘,产生特定物质或发出特殊气味以驱除昆虫。尽管对分类学特征的研究,棘在多刺植物中的作用和应用在国内外已有报道,目前缺乏对植物棘的系统概述。因此,本研究根据国内外对植物棘的研究,确定了植物棘的特征和类型,为确定植物棘的类型提供了明确的标准或依据。此外,功能,监管机制,阐述和总结了影响棘突形成的因素及其开发和应用前景。这项研究将有助于提高对类型的理解,植物刺的功能和调控机制,为植物从刺变种到非刺变种的遗传改良提供新的思路。
    Over a long period of evolution, plants have developed self-protection mechanisms, such as leaving seeds, dropping leaves, growing thorns, producing specific substances or emitting special odors to repel insects. Although studies on the taxonomic characteristics, functions and application of spines in spiny plants have been reported in China and abroad, a systematic overview of plant spines is currently lacking. This study therefore identifies the characteristics and types of plant spines based on domestic and international research on plant spines to provide clear criteria or bases for determining the types of plant spines. In addition, the functions, regulatory mechanisms, and factors influencing the formation of spines and the prospects for their development and application are described and summarized. This study will help to improve the understanding of the types, functions and regulatory mechanisms of plant spines and provide new ideas for the genetic improvement of plants from spiny to nonspiny varieties.
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  • 文章类型: Journal Article
    LophostreptusCook属的新种,1895年被描述,基于隐藏在其同源物LophostreptusregularisAttems的同系物中一个多世纪的标本,1909年,位于斯德哥尔摩自然历史博物馆(NRMS)和维也纳自然历史博物馆(NHMW)。为LophostreptusregularisAttems指定了一个选型,1909年,以稳定其分类法。更新了山的千足虫动物区系。乞力马扎罗山,坦桑尼亚提供。
    A new species of the genus Lophostreptus Cook, 1895 is described, based on specimens hidden for over a century among the syntypes of its congener Lophostreptusregularis Attems, 1909 housed in the Naturhistoriska Riksmuseet Stockholm (NRMS) and the Naturhistorisches Museum Wien (NHMW). A lectotype is designated for Lophostreptusregularis Attems, 1909 in order to stabilize its taxonomy. Updates to the millipede fauna of Mt. Kilimanjaro, Tanzania are provided.
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  • 文章类型: Journal Article
    自然生物多样性中心的非雀形目类型标本,莱顿被列为VandenHoekOstende等人的更新。(1997)国家自然历史博物馆的鸟类类型标本,莱顿,Part1.非雀形目\'和Roselaar和Prins(2000)\'阿姆斯特丹大学动物博物馆(ZMA)的鸟类类型标本清单,包括ZMA工作人员描述的分类单元,但ZMA中没有类型。列出了Temminck和Schlegel发布的所有新名称,即使类型不在Naturalis中,但在其他集合中。我们增加了380个新名字,并删除了最初在VandenHoekOstende等人中列出的13个名字。(1997)。
    The non-passerine type specimens in Naturalis Biodiversity Center, Leiden are listed as an update to Van den Hoek Ostende et al. (1997) \'Type-specimens of birds in the National Museum of Natural History, Leiden, Part 1. Non-Passerines\' and Roselaar and Prins (2000) \'List of type specimens of birds in the Zoological Museum of the University of Amsterdam (ZMA), including taxa described by ZMA staff but without types in the ZMA\'. All new names published by Temminck and Schlegel are listed, even when types are not in Naturalis but in other collections. We have added 380 new names and deleted 13 names originally listed in Van den Hoek Ostende et al. (1997).
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  • 文章类型: Journal Article
    自发性冠状动脉夹层是一种以冠状动脉壁破裂为特征的医疗状况,没有任何外部创伤。这种疾病与各种炎症有关,风湿病,和结缔组织疾病,以及与怀孕有关的变化。尽管对急性冠脉综合征的病因不太熟悉,它有相当大的死亡率,发病率高达4%。这篇评论将讨论这种情况,病理生理学,分类,危险因素,诊断技术,以及与自发性冠状动脉夹层相关的治疗方法。
    Spontaneous coronary artery dissection is a medical condition characterized by the rupture of the coronary artery wall, occurring without any external trauma. This ailment has been linked to various inflammatory, rheumatologic, and connective tissue disorders, as well as pregnancy-related changes. Despite being a less familiar cause of acute coronary syndrome, it has a considerable mortality rate, with incidence rates reaching up to 4%. This review will discuss the occurrence, pathophysiology, categorization, risk factors, diagnostic techniques, and treatment approaches related to spontaneous coronary artery dissection.
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