Hypertensive patients are likelier to have cognitive function decline (CFD). This study aimed to explore physical activity level, sleep disorders, and type of work that influenced intervention effects on cognitive function decline in hypertensive patients and to establish a decision tree model to analyze their predictive significance on the incidence of CFD in hypertensive patients.
This cross-sectional study recruited patients with essential hypertension from several hospitals in Shandong Province from May 2022 to December 2022. Subject exclusion criteria included individuals diagnosed with congestive heart failure, valvular heart disease, cardiac surgery, hepatic and renal dysfunction, and malignancy. Recruitment is through multiple channels such as hospital medical and surgical outpatient clinics, wards, and health examination centers. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Moreover, we obtained information on the patients\' type of work through a questionnaire and their level of physical activity through the International Physical Activity Questionnaire (IPAQ).
The logistic regression analysis results indicate that sleep disorder is a significant risk factor for CFD in hypertension patients(OR:1.85, 95%CI:[1.16,2.94]), mental workers(OR:0.12, 95%CI: [0.04,0.37]) and those who perform both manual and mental workers(OR: 0.5, 95%CI: [0.29,0.86]) exhibit protective effects against CFD. Compared to low-intensity, moderate physical activity(OR: 0.53, 95%CI: [0.32,0.87]) and high-intensity physical activity(OR: 0.26, 95%CI: [0.12,0.58]) protects against CFD in hypertension patients. The importance of predictors in the decision tree model was ranked as follows: physical activity level (54%), type of work (27%), and sleep disorders (19%). The area under the ROC curves the decision tree model predicted was 0.72 [95% CI: 0.68 to 0.76].
Moderate and high-intensity physical activity may reduce the risk of developing CFD in hypertensive patients. Sleep disorders is a risk factor for CFD in hypertensive patients. Hypertensive patients who engage in mental work and high-intensity physical activity effectively mitigate the onset of CFD in hypertensive patients.

Objective: To analyze the level of chromosome aberration in lymphocytes of medical radiation workers and its influencing factors. Methods: From July to September 2020, 252 medical workers in a tertiary hospital were selected as the study subjects and 107 preserviceworkers were selected as the control group. The Chromosomal aberrations of peripheral blood lymphocytes were measured using conventional cytogenetic analysis method, and the differences were analyzed. Results: The frequencies of dicentric puls centric ring, total chromosome-type aberrations, and abnormal detection rate in the radiation group were significantly higher than those in the control group (Z=2.59, 3.74, 9.99, P<0.05). There was significant difference in the frequencies of dicentric plus centric ring and total chromosome-type aberrations among different types of work (χ(2)=8.59, 8.17, 11.39, P<0.05), and the frequencies of dicentric plus centric ring were significantly higher in the interventional radiology group than those in diagnostic radiology (χ(2)=2.90, P<0.05), While the rates of acentric fragment and total chromosome-type aberrations were significantly higher in the nuclear medicine group than those in diagnostic radiology (χ(2)=2.81, 3.19, P<0.05). The difference in the abnormal detection rate of chromosome aberrations between different types of work was statistically significant (P<0.05), and the rate in the interventional radiology group was significantly higher than that in the diagnostic radiology group (χ(2)=7.66, P<0.05). There was no significant difference in chromosome aberration level and abnormal detection rate among different working ages (P>0.05). Poisson regression analysis indicated that the type of work is a risk factor for chromosomal aberration [IRR=2.31 (nuclear medicine group), 1.66 (Radiation therapy), and 1.78 (interventional group) ; P<0.05]. Conclusion: Ionizing radiation causes certain radiation damage to medical radiology workers, and the frequencies of chromosome aberration in the radiation workers of nuclear medicine and interventional radiology groups are relatively high, so radiation protection should be strengthened to ensure the health of relevant workers.
目的： 分析医疗放射工作人员淋巴细胞染色体畸变水平及影响因素。 方法： 于2020年7至9月，选取某三甲医院252名医疗放射工作人员作为放射组并依据工种、工龄分为不同亚组，以同期岗前体检拟从事放射工作的107名健康成年人为对照组，收集研究对照信息，采用常规细胞遗传学方法检测外周血淋巴细胞的染色体畸变，统计分析各组间检测结果。 结果： 放射组\"dic+r\"率、染色体总畸变率及异常检出率均明显高于对照组（Z=2.59、3.74、9.99，P<0.05）；不同工种间\"dic+r\"率、ace率及染色体总畸变率的差异有统计学意义（χ(2)=8.59、8.17、11.39，P<0.05），其中介入放射学组的\"dic+r\"率明显高于放射诊断组（χ(2)=2.90，P<0.05），核医学组的ace率及染色体总畸变率明显高于放射诊断组（χ(2)=2.81、3.19，P<0.05）；不同工种放射工作人员染色体畸变异常检出率差异有统计学意义（P<0.05），其中介入放射学组明显高于放射诊断组（χ(2)=7.66，P<0.05）。不同工龄组间染色体畸变水平及异常检出率的差异均无统计学意义（P>0.05）。Possion回归分析显示，与放射诊断组比较，核医学组、放射治疗组及介入放射学组（IRR=2.31、1.66、1.78，P<0.05）导致染色体畸变风险升高。 结论： 电离辐射对医疗放射工作人员产生一定的辐射损伤，核医学与介入放射学工作人员的染色体畸变水平相对较高，需加强辐射防护以保障相关从业人员的健康。.

BACKGROUND: Epidemiological studies show that an inappropriate healthy lifestyle is a major incidence factor, inter alia, for cardiovascular diseases, cancer, diabetes, obesity, as well as premature deaths, especially among men.
METHODS: In order to check the attitudes of men towards health and health behaviors, a questionnaire-based research was carried out among 600 men active on the labor market. Several standard questionnaire tools were used: the Positive Health Behaviors Scale (PHBS), the List of Personal Values for measuring the place of health in the value hierarchy; the Multidimensional Health Locus of Control Scale, the Work Ability Index, the Psychological Sex Inventory, and the Work-Life Balance Subscale of the Copenhagen Psychosocial Questionnaire (COPSOQ II). Additionally, an independent questionnaire was developed.
RESULTS: In the PHBS, men could score 0-111 pts; the average score was 70.98 pts. A high level of care for health expressed in the scores ranging 80-111 pts was achieved by less than one-third of the respondents. One of the 4 groups (referred to as the \"Active\") achieved the best result according to PHBS, with an average score of 77 pts. The worst group (referred to as the \"Frustrated\") achieved an average of 54.5 pts. The latter performed physical or mixed work, and half of them worked shifts, including nights.
CONCLUSIONS: The selected 4 groups were not found to differ from one another as much as the authors had expected, but they pointed to a very important aspect determining health care, namely socio‑‑economic factors. There is a great need to conduct health education among men in Poland, targeted especially at young, low-educated and blue-collar workers. The areas of lifestyle that need to be changed are: nutrition, physical activity and preventive examinations. Med Pr. 2021;72(4):351-62.

Shift work directly causes circadian disruption and reduces sleep quality. Physical activity is also associated with sleep quality. However, no study has reported the relationship between a specific level of physical activity and sleep quality. This study aimed to investigate the relationship between sleep quality and the amount of physical activity by stratifying subjects into gender and shift-work subgroups. Among those who participated in the Kangbuk Samsung Health Study in 2016-2017, data from 185,958 full-time workers were analysed. We evaluated their physical activity by metabolic equivalents (METs-min/week), sleep quality and shift work. A chi-squared test, a t test and logistic regression analysis were performed. An increase in sleep quality was found for the group with physical activity of 600-9,000 METs-min/week compared to that in the sedentary group among all subjects. In female day workers, the sleep quality of the group with 600-6,000 METs-min/week was significantly higher (odds ratio [OR], 0.760; 95% confidence interval [CI], 0.673-857) than that in the sedentary group. In male day workers, sleep quality increased when physical activity was increased up to 6,000-9,000 METs-min/week (OR, 0.760; 95% CI, 0.673-857). In female shift workers, there was no significant difference in sleep quality according to physical activity level. In male shift workers, sleep quality was better in the group with physical activity of 1,800-3,000 METs-min/week (OR, 0.826; 95% CI, 0.692-0.986) or 3,000-6,000 METs-min/week (OR, 0.771; 95% CI, 0.642-0.926). Optimal physical activity is good for sleep quality. The sleep quality of females is significantly worse than that of males in both day and shift workers.