背景:乳头瘤(HP)是乳腺样腺的腺瘤性增生。这些腺体优先位于阴道阴唇上,会阴和肛门皮肤.大约百分之九十的HP发生在外阴,肛门定位不太常见。
目的:分析肛门HP的临床和组织学特征,并根据文献将其与外阴上的HP进行比较。
方法:单中心回顾性分析(在圣约瑟夫医院集团的内科和外科直肠科,巴黎)的患者,根据切除样本的病理分析对其进行肛门HP诊断。
结果:2012年至2018年共纳入14名女性患者。平均年龄为48.2岁(22-70岁)。肿瘤,在所有情况下都是单身,无症状,进展非常缓慢。它位于所有患者的肛门皮肤上。它通常由一个直径在1厘米以下的圆形结节组成,几乎不突出,半透明,压抑和移动。在15%的患者中,肿瘤是溃疡的。组织学上,肿瘤表现出HP的常见特征。只有一次复发,切除6年后.
结论:肛门HP的临床和组织学方面与外阴相同,更好的记录,即一个小的,圆形,粉色,半透明或蓝色,和可移动的肿瘤,表面光滑,很少有溃疡或出芽,在大多数情况下无症状。所有HP均诊断为女性,位于肛门边缘。切除样品的组织病理学检查证实了诊断并排除了恶性肿瘤。肛门HP的频率可能被低估。
BACKGROUND: Hidradenoma papilliferum (HP) is an adenomatous proliferation of mammary-like glands. These glands are located preferentially on the vaginal labia, the perineum and the anal skin. About ninety percent of HP occur on the vulva, with anal localization being much less common.
OBJECTIVE: To analyze the clinical and histological characteristics of anal HP and compare them to those seen on the vulva based on the literature.
METHODS: A monocentric retrospective analysis (in the medical and surgical proctology department of the Saint-Joseph Hospital Group, Paris) of patients for whom a diagnosis of anal HP was made based on pathological analysis of a resected sample.
RESULTS: A total of 14 female patients were included between 2012 and 2018. The mean age was 48.2 years (22-70). The tumor, single in all cases, was asymptomatic with very slow progression. It was located on the anal skin in all patients. It generally consisted of a round nodule measuring under 1cm that was barely prominent, translucent, depressible and mobile. In 15% of patients the tumor was ulcerated. Histologically, the tumor displayed the usual characteristics of HP. Only one relapse was seen, six years after resection.
CONCLUSIONS: The clinical and histological aspects of anal HP are the same as those of the vulva, which are better documented, namely a small, rounded, pink, translucent or bluish, and mobile tumor, with a smooth surface, and more rarely ulceration or budding, and in most cases asymptomatic. All HP were diagnosed in women and were located at the anal margin. Histopathological examination of an excised sample confirms the diagnosis and rules out a malignant tumor. The frequency of anal HP may be underestimated.