背景:放射治疗可能会在照射区域内引起皮肤的一系列副作用。并非所有由放射治疗引起的皮肤反应作用都与某些形式的放射性皮炎有关,当非标准临床表现克服时,可能有必要采取适当的诊断工具,以免陷入错误诊断的陷阱。
■一名76岁男子在对腹股沟区软组织肉瘤进行新辅助放疗后接受了切除手术。手术后,他出现了与严重放射性皮炎相当的急性皮肤反应。尽管关心,他的临床状况恶化了.只有皮肤活检可以指导我们正确的诊断:这是放射治疗引起的大疱性类天疱疮的一种形式。随之而来的适当处理最终是坚决的。
结论:这些形式必须及时得到认可,一旦出现令人回味的临床表现,就进行皮肤活检。适当的治疗,包括局部或全身皮质治疗,在大多数情况下是坚决的。
BACKGROUND: Radiation therapy may cause a range of side effects of the skin within the irradiated area. Not of all the reactive effects of the skin induced by radiation therapy have to be related to some forms of radiodermatitis, and when non-standard clinical presentations overcome, it may be necessary to undertake appropriate diagnostic tools to not be in trap of wrong diagnosis.
UNASSIGNED: A 76 years-old man undertook resection surgery after a neoadjuvant radiation therapy for a soft tissue sarcoma of his groin region. After surgery, he developed an acute skin reaction comparable with a severe form of radiodermatitis. Despite cares, his clinical status got worse. Only skin biopsies guided us to the right diagnosis: it was a form of a bullous pemphigoid induced by radiation therapy. The consequent appropriate treatment was finally resolute.
CONCLUSIONS: These forms have to be recognized in time, to undertake skin biopsies as soon as an evocative clinical presentation appears. The appropriate treatment, which consists in local or systemic corticotherapy, is resolute in most cases.