Tricuspid valve repair

三尖瓣修复术
  • 文章类型: Case Reports
    该病例报告描述了首次使用术中电生理(EP)标测来评估EnCompass钳(AtriCure,Inc.,梅森,OH)在Cox-IV迷宫程序中。一名53岁的男性阵发性房颤和严重的二尖瓣反流,接受了二尖瓣修复术,并伴随着房颤的手术消融。使用雅培EnSitePrecision系统(雅培公司,芝加哥,IL)消融前,在使用AtriCureEnCompass钳进行初始射频消融后,在完整的Cox-IV迷宫程序完成后。预消融标测图显示左心房后壁约有80-85%的高电压区域。使用EnCompass夹钳的初始消融将高压区域减少到30-35%。在Cox-IV迷宫程序之后的最终地图显示出接近完全的电沉默,只有5-10%的心房表面保持高电压活动。这表示高电压区域从基线估计减少88%。除了一次需要直流电(DC)复律的术后房颤发作外,患者的术后病程并不复杂。此病例证明了术中EP标测在指导和确认手术消融手术疗效方面的实用性。以及将EnCompass钳与全Cox-IV迷宫相结合以实现全面的心房电隔离的有效性。EnCompass夹具可用于心脏跳动的消融,从而减少主动脉交叉钳夹时间,从而最大限度地减少总心肌缺血时间。
    This case report describes the first-in-man use of intraoperative electrophysiological (EP) mapping to evaluate the efficacy of the EnCompass clamp (AtriCure, Inc., Mason, OH) during a Cox-IV Maze procedure. A 53-year-old male with paroxysmal atrial fibrillation and severe mitral valve regurgitation underwent mitral valve repair with concomitant surgical ablation for atrial fibrillation. Intraoperative 3D EP mapping was performed using the Abbott EnSite Precision system (Abbott Inc., Chicago, IL) before ablation, after initial radiofrequency ablation with the AtriCure EnCompass clamp, and after the full Cox-IV Maze procedure was completed. The pre-ablation map showed approximately 80-85% high voltage areas in the posterior left atrial wall. Initial ablation with the EnCompass clamp reduced high voltage areas to 30-35%. The final map following the Cox-IV Maze procedure demonstrated near-complete electrical silence, with only 5-10% of the atrial surface retaining high voltage activity. This represents an estimated 88% reduction in high-voltage areas from baseline. The patient had an uncomplicated postoperative course apart from one episode of postoperative atrial fibrillation requiring direct current (DC) cardioversion. This case demonstrates the utility of intraoperative EP mapping in guiding and confirming the efficacy of surgical ablation procedures, as well as the effectiveness of combining the EnCompass clamp with a full Cox-IV Maze in achieving comprehensive atrial electrical isolation. The EnCompass clamp can be used for ablations with a beating heart, thus reducing the aortic cross-clamp time and therefore minimizing the total myocardial ischemia time.
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  • 文章类型: Journal Article
    微创二尖瓣修复/置换已成为一种被广泛接受的治疗二尖瓣疾病的手术方法。不断的技术进步促进了这一程序的完善,提高安全性,减少手术创伤,更快的恢复时间。尽管取得了这些进步,当与其他手术结合使用时,关于微创复杂二尖瓣修复手术的数据仍然很少。
    在2008年11月至2022年12月之间,有153名患者接受了使用微创技术的手术。所有患者均接受了严重二尖瓣关闭不全/狭窄的二尖瓣手术,并至少进行了一次三尖瓣修复手术(n=52,34%)。卵圆孔未闭或房间隔缺损封堵术(n=34,22.2%),左心耳封堵术(n=25,16.3%),或电生理程序(n=101,66.0%)。98例患者(64.1%)同时进行两次手术,49例(32%)患者的三次伴随手术,6例患者(3.9%)同时进行4次手术。
    99.3%的患者(n=152)手术成功,1例患者由于收缩期前运动现象,在术后第一天需要对二尖瓣修复术进行修正.136例(88.9%)患者行二尖瓣修复术,而15例患者(9.8%)由于严重的二尖瓣狭窄,根据术前决定接受了二尖瓣置换术,和两名患者(1.3%)接受了其他二尖瓣手术。在接受额外迷宫手术的101例患者中,有86例(85.1%)在治疗房颤方面取得了成功。30天死亡率为0.7%,一名病人死于呼吸衰竭.7例患者发生神经系统并发症(4.6%)。5年随访时,再手术的自由度为98%,10年随访时为96.5%。
    微创二尖瓣手术,即使与伴随程序一起进行,作为一种可重复和安全的技术,具有出色的结果。必须向微创外科的下一个前沿迈进,鼓励有经验的外科医生使用微创方法进行更复杂的手术。这些结果有助于设想通过在合适的患者中完全通过内窥镜手段执行复杂的二尖瓣手术和相关干预来扩展微创手术的界限。
    UNASSIGNED: Minimally invasive mitral valve repair/replacement has emerged as a widely accepted surgical approach for managing mitral valve disorders. Continuous technological progress has contributed to the refinement of this procedure, leading to improved safety, decreased surgical trauma, and faster recovery times. Despite these advancements, there remains a scarcity of data concerning minimally invasive complex mitral valve repair surgeries when combined with additional procedures.
    UNASSIGNED: Between November 2008 and December 2022, 153 patients underwent an operation using a minimally invasive technique. All patients underwent mitral valve surgery for severe mitral valve insufficiency/stenosis in combination with at least one additional procedure for tricuspid valve repair (n = 52, 34%), patent foramen ovale or atrial septal defect closure (n = 34, 22.2%), left atrial appendage occlusion (n = 25, 16.3%), or electrophysiological procedure (n = 101, 66.0%). Two concomitant procedures were conducted in 98 patients (64.1%), three concomitant procedures in 49 patients (32%), and four concomitant procedures in 6 patients (3.9%).
    UNASSIGNED: Surgical success was achieved in 99.3% of the patients (n = 152), one patient required a revision of the mitral valve repair on the first postoperative day due to systolic anterior motion phenomenon. Mitral valve repair was performed in 136 patients (88.9%), while 15 patients (9.8%) received a mitral valve replacement as per a preoperative decision due to severe mitral valve stenosis, and two patients (1.3%) underwent other mitral valve procedures. Therapeutic success in treating atrial fibrillation was achieved in 86 patients (85.1%) of the 101 who received an additional maze-procedure. The 30-day mortality rate was 0.7%, with one patient succumbing to respiratory failure. Neurological complications occurred in 7 patients (4.6%). Freedom from reoperation was calculated as 98% at 5-year follow-up and 96.5% at 10-year follow-up.
    UNASSIGNED: Minimally invasive mitral valve surgery, even when performed alongside concomitant procedures, stands out as a reproducible and safe technique with outstanding outcomes. It is imperative to advance towards the next frontier in minimally invasive surgery, encouraging experienced surgeons to undertake more complex procedures using minimally invasive approaches. These results help envision extending the boundaries of minimally invasive surgery by performing complex mitral valve procedures and associated interventions entirely through endoscopic means in suitable patients.
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  • 文章类型: Case Reports
    心脏黏液瘤是最常见的心脏良性肿瘤,临床表现因肿瘤大小而异。症状可以从无症状和轻度非特异性表现到严重的阻塞性心脏和全身性表现。该病例报告描述了一名68岁的女性患者,该患者患有急性失代偿性心力衰竭。诊断评估显示左心房粘液瘤导致严重的二尖瓣阻塞。病人接受了紧急心脏手术切除肿瘤,并发严重的二尖瓣和三尖瓣反流。瓣膜更换和维修后,患者需要体外生命支持.尽管有这些复杂性,她获得了显着的康复,并状况良好。在后续行动中,她仍然无症状,没有心脏代偿失调的迹象。该病例强调了在此类病例中考虑将心脏粘液瘤作为鉴别诊断以防止潜在并发症的重要性。
    Cardiac myxomas are the most common benign tumors of the heart, with clinical manifestations varying significantly based on tumor size. Symptoms can range from asymptomatic and mild non-specific presentations to severe obstructive cardiac and systemic findings. This case report describes a 68-year-old female patient who presented with acute decompensated heart failure. Diagnostic evaluation revealed a left atrial myxoma causing significant mitral valve obstruction. The patient underwent emergency cardiac surgery for tumor removal, complicated by severe mitral and tricuspid valve regurgitation. Following valve replacement and repair, the patient required extracorporeal life support. Despite these complexities, she achieved significant recovery and was discharged in good condition. At follow-up, she remained asymptomatic with no signs of cardiac decompensation. This case highlights the importance of considering cardiac myxoma as a differential diagnosis in such cases to prevent potential complications.
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  • 文章类型: Journal Article
    关于美国三尖瓣手术(TVS)的使用和结果的种族/族裔和性别差异的数据很少。作者旨在评估种族/民族和性别对TVS的利用和结果的影响。
    作者分析了2016年至2020年的全国住院患者样本数据库,以确定TVS的住院情况。使用逻辑回归模型确定TVS结果中的种族/种族和性别差异。
    在2016年至2020年之间,确定了19.395例TVS住院。在手术三尖瓣修复术(STVr)(331对493对634,P<0.01)和手术三尖瓣置换术(STVR)(312对601对728,P<0.01)中,黑人和西班牙裔患者的利用率(手术次数/100,000住院)低于白人患者。同样,与男性相比,女性的STVr(1021比1364,P<0.01)和STVR(930比1,316,P<0.01)的使用率较低。与接受TVS的白人相比,所有女性急性肾损伤的几率较低[校正比值比(aOR)0.65,95%CI0.55-0.78],输血的几率较高(aOR1.30,95%CI1.07-1.59),黑人男性输血的几率较高(aOR1.59,95%CI1.08-2.35)。各组间院内死亡率和其他手术并发症相似(均P>0.05)。
    在美国使用TVS时存在明显的种族/族裔和性别差异。需要进一步的研究来了解这些差异的原因,并确定缓解这些差异的有效策略。
    UNASSIGNED: Data on racial/ethnic and sex disparities in the utilization and outcomes of tricuspid valve surgery (TVS) in the United States are scarce. The authors aimed to evaluate the impact of race/ethnicity and sex on the utilization and outcomes of TVS.
    UNASSIGNED: The authors analyzed the National Inpatient Sample database from 2016 to 2020 to identify hospitalizations for TVS. Racial/ethnic and sex disparities in TVS outcomes were determined using logistic regression models.
    UNASSIGNED: Between 2016 and 2020, 19 395 hospitalizations for TVS were identified. The utilization rate (number of surgeries/100,000 hospitalizations) was lower in Black and Hispanic patients compared with White patients for surgical tricuspid valve repair (STVr) (331 versus 493 versus 634, P<0.01) and surgical tricuspid valve replacement (STVR) (312 versus 601 versus 728, P<0.01). Similarly, the utilization rate was lower for women compared with men for STVr (1021 versus 1364, P<0.01) and STVR (930 versus 1,316, P<0.01). Compared to White men undergoing TVS, all women had lower odds of acute kidney injury [adjusted odds ratio (aOR) 0.65, 95% CI 0.55-0.78] and higher odds of blood transfusion (aOR 1.30, 95% CI 1.07-1.59), and Black men had higher odds of blood transfusion (aOR 1.59, 95% CI 1.08-2.35). In-hospital mortality and other surgical complications were similar between all groups (all P>0.05).
    UNASSIGNED: Significant racial/ethnic and sex disparities exist in the utilization of TVS in the United States. Further studies are needed to understand the reasons for these disparities and to identify effective strategies for their mitigation.
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  • 文章类型: Journal Article
    功能性三尖瓣反流(FTR)是三尖瓣反流(TR)的常见类型,特别是在左心瓣膜疾病的病例中。历史上,心脏外科医生并不重视FTR,而是主要关注治疗左心瓣膜疾病.然而,随着研究的进展,很明显,严重的TR显著影响心脏瓣膜手术的预后.此外,在治疗三尖瓣和左心脏病治疗的同时,观察到术后心功能和生活质量显著改善.本文旨在回顾FTR手术治疗的当前方法和时机,同时分析现有三尖瓣手术策略的局限性。
    Functional tricuspid regurgitation (FTR) is a common type of tricuspid regurgitation (TR), particularly in cases of left heart valve disease. Historically, cardiac surgeons have not placed much emphasis on FTR and instead focused primarily on managing left heart valve disease. However, as research has progressed, it has become evident that severe TR significantly impacts the prognosis of heart valve surgery. Furthermore, significant improvements in postoperative cardiac function and quality of life have been observed when addressing the tricuspid valve alongside left heart disease management. This article aims to review current approaches for and timing of the surgical management of FTR while also analyzing the limitations of existing tricuspid surgical strategies.
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  • 文章类型: Journal Article
    目的:描述在英国接受三瓣膜手术的患者不断变化的人口趋势和早期结果,2000-2019年之间。
    方法:我们计划对国家注册数据进行回顾性分析,包括接受三瓣手术的患者的所有病因。我们排除了处于严重术前状态的患者和那些错过入院日期的患者。研究队列分为5个连续的4年队列(A组,B,C,D和E)。主要结果是住院死亡率,次要结果包括延长入院时间,重新探查出血,术后中风和术后透析。二元logistic回归模型用于建立死亡率的独立预测因子。中风,在这一高风险队列中进行术后透析和再出血探查。
    结果:我们确定了2000年至2019年间在英国接受三瓣膜手术的1,750名患者。三瓣膜手术占数据集中所有患者的3.1%。患者的总体平均年龄为68.5岁±12,从A组的63岁±12增加到E组的69岁±12(p<0.001)。总体住院死亡率为9%,从A组的21%下降到E组的7%(p<0.001)。出血的总再探查率(11%,p=0.308)和术后透析(11%,p=0.066)在整个观察到的时间段内保持较高。三瓣膜置换,再次胸骨切开术和术前左心室射血分数差是死亡率的独立预测因子.
    结论:三瓣膜手术在英国仍然很少见。随着时间的推移,三瓣膜手术的术后早期结果有所改善。重做胸骨切开术是死亡率的重要预测指标。在技术上可能的情况下,应尝试修复二尖瓣和/或三尖瓣。
    OBJECTIVE: To describe evolving demographic trends and early outcomes in patients undergoing triple-valve surgery in the UK between 2000 and 2019.
    METHODS: We planned a retrospective analysis of national registry data including patients undergoing triple-valve surgery for all aetiologies of disease. We excluded patients in a critical preoperative state and those with missing admission dates. The study cohort was split into 5 consecutive 4-year cohorts (groups A, B, C, D and E). The primary outcome was in-hospital mortality, and secondary outcomes included prolonged admission, re-exploration for bleeding, postoperative stroke and postoperative dialysis. Binary logistic regression models were used to establish independent predictors of mortality, stroke, postoperative dialysis and re-exploration for bleeding in this high-risk cohort.
    RESULTS: We identified 1750 patients undergoing triple-valve surgery in the UK between 2000 and 2019. Triple valve surgery represents 3.1% of all patients in the dataset. Overall mean age of patients was 68.5 ± 12 years, having increased from 63 ±12 years in group A to 69 ± 12 years in group E (P < 0.001). Overall in-hospital mortality rate was 9%, dropping from 21% in group A to 7% in group E (P < 0.001). Overall rates of re-exploration for bleeding (11%, P = 0.308) and postoperative dialysis (11%, P = 0.066) remained high across the observed time period. Triple valve replacement, redo sternotomy and poor preoperative left ventricular ejection fraction emerged as strong independent predictors of mortality.
    CONCLUSIONS: Triple-valve surgery remains rare in the UK. Early postoperative outcomes for triple valve surgery have improved over time. Redo sternotomy is a significant predictor of mortality. Attempts should be made to repair the mitral and/or tricuspid valves where technically possible.
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  • 文章类型: Journal Article
    背景:三尖瓣区域是各种心脏介入治疗的重要区域。特别是,在手术干预期间,应考虑右冠状动脉和三尖瓣瓣环之间的空间关系.这项研究的目的是提供该区域临床解剖学和地形图的准确描述。
    方法:我们分析了107次计算机断层扫描(44%为女性,年龄62.1±9.4岁)的三尖瓣区域。将三尖瓣环的自由壁的圆周分成13个环形点,并在每个点处进行测量。还研究了危险区的患病率(动脉和瓣环之间的距离小于2mm)。
    结果:在所研究的病例中,有20.56%发现了危险区。危险区域的发生率最高,距离最小的是位于小叶后部插入的三尖瓣环点。没有观察到性别特异性差异。
    结论:右冠状动脉医源性损伤的最高风险是在三尖瓣环的后部。
    BACKGROUND: The region of the tricuspid valve is an important area for various cardiac interventions. In particular, the spatial relationships between the right coronary artery and the annulus of the tricuspid valve should be considered during surgical interventions. The aim of this study was to provide an accurate description of the clinical anatomy and topography of this region.
    METHODS: We analyzed 107 computed tomography scans (44% female, age 62.1 ± 9.4 years) of the tricuspid valve region. The circumference of the free wall of the tricuspid valve annulus was divided into 13 annular points and measurements were taken at each point. The prevalence of danger zones (distance between artery and annulus less than 2 mm) was also investigated.
    RESULTS: Danger zones were found in 20.56% of the cases studied. The highest prevalence of danger zones and the smallest distances were found at the annular points of the tricuspid valve located at the posterior insertion of the leaflets, without observed sex-specific differences.
    CONCLUSIONS: The highest risk of iatrogenic damage to the right coronary artery is in the posterior part of the tricuspid valve annulus.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    感染性心内膜炎是一种具有挑战性和危及生命的临床疾病,影响天然和人工心脏瓣膜。心内膜,和植入的心脏设备。右侧感染性心内膜炎约占所有感染性心内膜炎的5-10%,通常与静脉用药有关。心内装置,中心静脉导管,先天性心脏病.三尖瓣参与了90%的右侧感染性心内膜炎。三尖瓣感染性心内膜炎的主要治疗基于长期静脉抗生素。当需要手术时,已经提出了不同的干预措施,从瓣膜切除术到各种类型的瓣膜修复,再到完全更换瓣膜。在这些患者中还提出了使用AngioVac系统经皮去除植被。这篇叙述性综述的目的是概述当前的手术选择,并讨论三尖瓣感染性心内膜炎患者不同手术策略的结果。
    在线版本包含补充材料,可在10.1007/s12055-023-01650-0获得。
    Infective endocarditis represents a challenging and life-threatening clinical condition affecting native and prosthetic heart valves, endocardium, and implanted cardiac devices. Right-sided infective endocarditis account for approximately 5-10% of all infective endocarditis and are often associated with intravenous drug use, intracardiac devices, central venous catheters, and congenital heart disease. The tricuspid valve is involved in 90% of right-side infective endocarditis. The primary treatment of tricuspid valve infective endocarditis is based on long-term intravenous antibiotics. When surgery is required, different interventions have been proposed, ranging from valvectomy to various types of valve repair to complete replacement of the valve. Percutaneous removal of vegetations using the AngioVac system has also been proposed in these patients. The aim of this narrative review is to provide an overview of the current surgical options and to discuss the results of the different surgical strategies in patients with tricuspid valve infective endocarditis.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12055-023-01650-0.
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  • 文章类型: Case Reports
    我们报告了一例45岁的男子,表现为心动过速和心悸。超声心动图提示三尖瓣重度反流。我们怀疑在17年前的一次机动车事故中,由于高能创伤而导致的三尖瓣创伤性损伤。他做了胸骨切开术,他的三尖瓣通过腱索重建修复,缩进闭合,和环形瓣膜成形术。术后期间平安无事,手术后10天就出院了.该报告强调了超声心动图诊断与创伤相关的原发性三尖瓣反流的价值。以及早期诊断的重要性,以便在不可逆转的损伤发生之前进行手术干预。
    外伤性三尖瓣反流是一种罕见的闭合性胸部创伤的心血管并发症。三尖瓣损伤的机制被认为是继发于突然撞击,导致在舒张末期胸骨对右心室的前后压迫。这种损伤通常是偶然发现的,或者可能会错过,直到患者出现严重的三尖瓣反流导致的右心衰竭症状。
    We report a case of a 45-year-old man presenting with tachycardia and palpitation. Echocardiography indicated severe tricuspid regurgitation. We suspected traumatic tricuspid damage due to high energy trauma in a motor vehicle accident 17 years earlier. He underwent a sternotomy, and his tricuspid valve was repaired with chordal reconstruction, indentation closure, and ring annuloplasty. The postoperative period was uneventful, and he was discharged 10 days after the operation. This report highlights the value of echocardiography for diagnosis of primary tricuspid regurgitation related to trauma, and the importance of early diagnosis to allow surgical intervention before irreversible damage occurs.
    UNASSIGNED: Traumatic tricuspid regurgitation is a rare cardiovascular complication of blunt chest trauma. The mechanism of the tricuspid valve injury is thought to be secondary to sudden impact causing an anteroposterior compression of the right ventricle by the sternum in end-diastole. This injury is often incidentally identified or can be missed until the patient experiences symptoms of right heart failure resulting from severe tricuspid regurgitation.
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