Tratamiento preventivo

Tratamiento 预防
  • 文章类型: Journal Article
    背景:三叉神经痛(TN)是一种慢性神经性疼痛障碍,影响三叉神经的一个或多个分支。尽管全球流行率相对较低,TN是神经内科和急诊科的重要医疗保健问题,因为该病的诊断和治疗困难,对患者的生活质量有重大影响。由于所有这些原因,西班牙神经病学会的头痛研究小组已经就TN的管理达成了共识。
    方法:本文件由一组专门研究头痛的神经学家起草,他使用了国际头痛协会的术语。我们分析了已发表的关于TN诊断和治疗的科学证据,并建立了具有证据水平的实用建议。
    结论:TN的诊断基于临床标准。由三叉神经病变或疾病引起的疼痛分为TN和疼痛性三叉神经病变,根据国际头痛疾病分类,第三版。TN进一步细分为经典,次要,或者特发性,根据病因。临床诊断为TN的患者建议行脑部MRI检查,以排除次要原因。在检测神经血管压迫的MRI研究中,FIESTA,驱动器,建议使用orCISS序列。药物治疗是所有患者的初始选择。在选定的耐药疼痛或耐受性较差的病例中,应该考虑手术。
    BACKGROUND: Trigeminal neuralgia (TN) is a chronic neuropathic pain disorder affecting one or more branches of the trigeminal nerve. Despite its relatively low global prevalence, TN is an important healthcare problem both in neurology departments and in emergency departments due to the difficulty of diagnosing and treating the condition and its significant impact on patients\' quality of life. For all these reasons, the Spanish Society of Neurology\'s Headache Study Group has developed a consensus statement on the management of TN.
    METHODS: This document was drafted by a panel of neurologists specialising in headache, who used the terminology of the International Headache Society. We analysed the published scientific evidence on the diagnosis and treatment of TN and establish practical recommendations with levels of evidence.
    CONCLUSIONS: The diagnosis of TN is based on clinical criteria. Pain attributed to a lesion or disease of the trigeminal nerve is divided into TN and painful trigeminal neuropathy, according to the International Classification of Headache Disorders, third edition. TN is further subclassified into classical, secondary, or idiopathic, according to aetiology. Brain MRI is recommended in patients with clinical diagnosis of TN, in order to rule out secondary causes. In MRI studies to detect neurovascular compression, FIESTA, DRIVE, or CISS sequences are recommended. Pharmacological treatment is the initial choice in all patients. In selected cases with drug-resistant pain or poor tolerance, surgery should be considered.
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  • 文章类型: Journal Article
    背景:偏头痛影响西班牙超过450万人,产生了相当大的社会经济影响。尽管已经发布了国家和国际准则,偏头痛患者的管理,尤其是那些患有慢性偏头痛的人,是不够的。
    方法:我们在西班牙的40名初级保健(PC)医生中进行了一项调查,这是一项涉及来自5个国家的201名医生的欧洲项目的一部分。
    结果:大多数参与者诊断为发作性偏头痛和慢性偏头痛(93%vs65%);82.5%表示他们没有将这些患者转诊给专家,100%的PC医生表示他们负责患者随访。PC中用于诊断和随访的主要工具是临床访谈,病史,和病人的日记。我们的数据显示,所规定的治疗方法不符合国家和国际指南。没有转诊患者的参与者估计,只有48%的患者接受了预防性治疗,疗效评估是基于患者的感知。70%的受访者表示需要偏头痛培训。最后,100%的参与者认为,病史记录和转诊指南对于PC中偏头痛的管理至关重要或有用。
    结论:调查结果表明,需要对PC进行培训和指导,以改善偏头痛患者的诊断和管理,尤其是慢性偏头痛。
    BACKGROUND: Migraine affects more than 4.5 million people in Spain, resulting in a considerable socioeconomic impact. Although national and international guidelines have been published, the management of patients with migraine, especially those with chronic migraine, is inadequate.
    METHODS: We conducted a survey among 40 primary care (PC) physicians in Spain as part of a European project involving 201 physicians from 5 countries.
    RESULTS: Most participants issued diagnoses of episodic migraine and chronic migraine (93% vs 65%); 82.5% indicated that they did not refer these patients to specialists, and 100% of PC physicians stated that they were responsible for patient follow-up. The main tools used in PC for diagnosis and follow-up were clinical interviews, medical histories, and the patient diaries. Our data revealed that the treatments prescribed were not in accordance with the national and international guidelines. Participants who did not refer patients estimated that only 48% of patients received preventive treatment, and that the assessment of efficacy was based on patient perception. Seventy percent of respondents indicated a need for migraine training. Finally, 100% of participants considered that a guide for medical history taking and referral would be essential or useful for the management of migraine in PC.
    CONCLUSIONS: The survey results revealed a need for training and guidance in PC to improve the diagnosis and management of patients with migraine, particularly chronic migraine.
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  • 文章类型: Journal Article
    BACKGROUND: Medication overuse headache is a secondary headache in which the regular or frequent use of analgesics can increase the frequency of the episodes, causing the transition from episodic to chronic headache. The prevalence of medication overuse headache is approximately 1-2%, with higher rates among women aged 30-50 years and with comorbid psychiatric disorders such as depression or anxiety, or other chronic pain disorders. It is important to be familiar with the management of this disease. To this end, the Spanish Society of Neurology\'s Headache Study Group has prepared a consensus document addressing this disorder.
    METHODS: These guidelines were prepared by a group of neurologists specialising in headache after a systematic literature review and provides consensus recommendations on the proper management and treatment of medication overuse headache. The treatment of medication overuse headache is often complex, and is based on 4 fundamental pillars: education and information about the condition, preventive treatment, discontinuation of the drug being overused, and treatment for withdrawal symptoms. Follow-up of patients at risk of recurrence is important.
    CONCLUSIONS: We hope that this document will be useful in daily clinical practice and that it will update and improve understanding of medication overuse headache management.
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  • 文章类型: Journal Article
    OnabotulinumtoxinA has been demonstrated to be effective as a preventive treatment in patients with chronic migraine (CM). Five years after the approval of onabotulinumtoxinA in Spain, the Headache Study Group of the Spanish Society of Neurology considered it worthwhile to gather a group of experts in treating patients with CM in order to draw up, based on current evidence and our own experience, a series of guidelines aimed at facilitating the use of the drug in daily clinical practice. For this purpose, we posed 12 questions that we ask ourselves as doctors, and which we are also asked by our patients. Each author responded to one question, and the document was then reviewed by everyone. We hope that this review will constitute a practical tool to help neurologists treating patients with CM.
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  • 文章类型: Journal Article
    背景:颅内神经麻醉阻滞常用于治疗头痛。没有证据表明这种治疗偏头痛的迹象。我们旨在使用特定的适应症标准评估其作为偏头痛预防性治疗的有效性。
    方法:在2009年1月至2013年5月之间,我们为有预防性药物不耐受或失败史的偏头痛患者提供了颅神经阻滞。我们选择触诊至少一个枕大神经(GON)或眶上神经(SON)的压痛患者。3个月时的反应被归类为完全反应(无疼痛),部分反应(头痛发作的严重程度或频率降低至少50%),或者没有回应。
    结果:60例患者(52例女性,男性8人,平均年龄40.6±12.4岁,范围19-76)。最常见的程序是两侧封锁GON和SON。23例患者(38.3%)出现持续至少2周的完全缓解,24例患者有部分反应(40%),13例(21.7%)无反应。在提出完整回应的小组中,年龄和偏头痛病史的长短显著降低.没有检测到严重的副作用。反应时间为2周至3个月。
    结论:以触诊触痛为纳入标准的颅神经阻滞作为偏头痛的预防性治疗是安全有效的。我们系列中的最佳反应是在偏头痛病史较短的年轻患者中观察到的。
    BACKGROUND: Anaesthetic blockade of pericranial nerves is frequently used to treat headache disorders. There is no evidence on indication of this treatment for migraine. We aim to evaluate its effectiveness as a preventive treatment for migraine using specific indication criteria.
    METHODS: Between January 2009 and May 2013 we offered pericranial nerve blockade to migraine patients with a history of preventive drug intolerance or failure. We selected patients with tenderness to palpation of at least one greater occipital nerve (GON) or supraorbital nerve (SON). Responses at 3 months were categorised as complete response (no pain), partial response (reduction of at least 50% in severity or frequency of headache episodes), or no response.
    RESULTS: Anaesthetic blockade was performed in 60 patients (52 females, 8 males; mean age 40.6 ± 12.4 years, range 19-76). The most common procedure was blockade of GON and SON on both sides. Complete response lasting at least 2 weeks was recorded in 23 patients (38.3%), with partial response in 24 patients (40%), and no response in 13 (21.7%). In the group presenting complete response, age and length of history of migraine were significantly lower. No severe side effects were detected. Response time ranged from 2 weeks to 3 months.
    CONCLUSIONS: Pericranial nerves blockade using tenderness to palpation as an inclusion criterion is safe and potentially effective as prophylactic treatment for migraine. The best responses in our series were observed in younger patients with shorter histories of migraine.
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