在变性女性(TGW)的性别确认手术(GAS)期间,前列腺仍未切除,并可能在以后的生活中发展为恶性肿瘤。我们试图评估GASTGW后的前列腺癌意识(PCA)。
研究人员实施了一项横断面研究,并招募了没有医学背景的泰国GAS后TGW样本。预测变量被归类为人口统计,临床,Operative,或术后。结果变量为PCA(是/否)。计算了适当的统计数据,p值≤0.05被认为具有统计学意义。
样本包括100个泰国后GASTGW(4%双性恋,12%本科[或更高]毕业生,51%的服务人员,64%的人每月净收入<40,000TB[或大约。1050欧元],92%由整形外科医生手术),平均年龄为26.2±5.4岁(范围:18-45岁)。在双变量分析中,PCA与教育水平显着相关(p=0.007;调整后的奇数比率[ORadj。]:5.85;95%置信区间[95%CI]:1.65-20.69),手术时间≥10年(p=0.01;ORadj。:0.16;95%CI:0.04-0.76),剩余前列腺的自我识别(p=0.0001;ORadj。:0.02;95%CI:0-0.12),并通过GAS算子强调PCA(p=0.01;ORadj。:0.07;95%CI:0.01-0.63)。多元线性回归分析显示,这四个预测因子之间呈正相关(r=0.78;p=0.0001),并继续确认对TGW中的PCA的积极影响,其中高学历和前列腺的认识(r=0.56;p=0.04)或操作员对PCA的信息(r=0.68;p=0.003)。
GSA运营商应集中告知TGW残余前列腺和PC风险,特别是那些受过中低教育的人。
The prostate gland remains unresected during gender-affirming surgery (GAS) for transgender women (TGW), and may develop malignancies in later life. We sought to evaluate prostate cancer awareness (PCA) among post-GAS TGW.
The investigators implemented a cross-sectional study and enrolled a sample of Thai post-GAS TGW without medical background. Predictor variables were categorized as demographic, clinical, operative, or postoperative. The outcome variable was PCA (yes/no). Appropriate statistics were computed, and a p-value ≤ 0.05 was considered statistically significant.
The sample consisted of 100 Thai post-GAS TGW (4% bisexual, 12% bachelor [or higher] graduates, 51% service workers, 64% had monthly net income <40,000 TB [or ca. 1050 Euro], 92% operated by plastic surgeons) with a mean age of 26.2 ± 5.4 years (range: 18-45). On bivariate analysis, PCA was significantly associated with educational level (p = 0.007; adjusted odd ratio [ORadj. ]: 5.85; 95% confidence interval [95% CI]: 1.65-20.69), being operated ≥ 10 years (p = 0.01; ORadj. : 0.16; 95% CI: 0.04-0.76), self-recognition of the remaining prostate gland (p = 0.0001; ORadj. : 0.02; 95% CI: 0-0.12), and emphasis on PCA by the GAS operator (p = 0.01; ORadj. : 0.07; 95% CI: 0.01-0.63). Multiple linear regression analysis revealed a statistically significant, positive correlation (r = 0.78; p = 0.0001) among these four predictors, and continued to confirm the positive effect on PCA in TGW with high education and realization of the prostate gland (r = 0.56; p = 0.04) or information on PCA by the operator (r = 0.68; p = 0.003).
The GSA operator should intensively inform TGW about the remnant prostate and the risk of PC, especially those with low and middle levels of education attained.