背景许多类型的研究已经研究了糖尿病人口统计学特征中基于年龄和性别的差异。这些差异进一步扩展到糖尿病相关的合并症。血脂异常是与糖尿病相关的常见并发症,并导致心血管发病率大幅增加。该研究旨在比较新诊断的2型糖尿病(T2DM)中不同年龄段的男性和女性之间的血脂异常模式。方法学回顾性数据库研究在Faiha专业糖尿病,内分泌,和代谢中心(FDEMC),巴士拉,伊拉克南部。我们纳入了2018年1月至2022年10月期间新诊断和药物幼稚T2DM的成年患者。身体质量指数(BMI)形式的患者数据,血红蛋白A1c(HbA1c),空腹血糖(FBG),随机血糖(RBG),总胆固醇(TC),甘油三酯(TG),高密度脂蛋白胆固醇(HDL-C),和低密度脂蛋白胆固醇(LDL-C)用于比较。结果35岁以下男性HbA1c水平明显升高,FBG,和TG与女性相比,随着HDL-C的水平显着降低然而,BMI没有显着差异,RBG,TC,和LDL-C在这项研究中,年龄在35至44岁之间的女性表现出明显更高的BMI和HDL-C水平,而男性表现出更高水平的HbA1c,FBG,RBG,TG。然而,TC和LDL-C水平无显著差异。在45至55岁的年龄组中发现了类似的结果,唯一的例外是FBG,变得无关紧要。在55至64岁的患者中,BMI,HDL-C,女性TC明显高于女性(P<0.05)。在65岁以上的患者中,女性的BMI和HDL-C仍然明显较高,而男性RBG明显较高。在其他参数(HbA1c,TG,TC,和LDL-C)。结论在54岁及以下的患者中,男性更容易出现严重的高血糖症,较高的TG,与T2DM诊断时的女性相比,HDL-C较低。在老年患者中,这种模式丢失了,仅观察到显著较低的HDL-C。
Background Age- and gender-based differences in diabetes demographic characteristics have been studied in many types of research. These differences extend further to diabetes-related comorbidities. Dyslipidemia is a common complication associated with diabetes and causes a substantial increase in cardiovascular morbidity. The study aims to compare the pattern of dyslipidemia between males and females among different age categories in newly diagnosed type 2 diabetes mellitus (T2DM). Methodology A retrospective database study was conducted at Faiha Specialized Diabetes, Endocrine, and Metabolism Center (FDEMC), Basrah, Southern Iraq. We included adult patients with newly diagnosed and drug naïve T2DM between January 2018 and October 2022. Patients\' data in the form of body mass index (BMI), hemoglobin A1c (HbA1c), fasting blood glucose (FBG), random blood glucose (RBG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were used for comparisons. Results Below the age of 35, males exhibited significantly higher levels of HbA1c, FBG, and TG compared to females, along with a significantly lower level of HDL-C. However, there were no significant differences in BMI, RBG, TC, and LDL-C. Between the ages of 35 and 44, females in this study demonstrated significantly higher BMI and HDL-C levels, while males exhibited higher levels of HbA1c, FBG, RBG, and TG. However, there were no significant differences observed in TC and LDL-C levels. Similar results were found among the age group 45 to 55, with the only exception being FBG, which became nonsignificant. In patients between 55 and 64 years old, BMI, HDL-C, and TC were significantly higher in females (P < 0.05). In patients aged above 65 years, BMI and HDL-C remained significantly higher in females, while RBG was significantly higher in males. No significant differences were observed among other parameters (HbA1c, TG, TC, and LDL-C). Conclusions In patients aged 54 years and younger, males were significantly more likely to have severe hyperglycemia, higher TG, and lower HDL-C compared to females at the time of T2DM diagnosis. In older patients, this pattern is lost, with only a significantly lower HDL-C observed.