■维生素因据称对头发有益而在医生和患者中受到欢迎,皮肤,和指甲健康。安全和有效的治疗指甲疾病,其中许多是慢性疾病,是需要的。
■我们对评估口服,topic,和用于治疗指甲疾病的病灶内维生素/维生素衍生物,包括黄指甲综合症,脆性指甲综合征,甲癣,习惯性的指甲畸形,甲周/甲下疣,和指甲牛皮癣。审查了49篇文章。有充分的证据支持使用他扎罗汀和维生素D类似物治疗指甲牛皮癣。我们发现用维生素/维生素衍生物治疗其他指甲疾病的总体证据有限,需要进一步的研究来支持它们的使用。
■除了外用他扎罗汀和维生素D类似物治疗指甲牛皮癣,局部治疗指甲疾病的证据有限,口服,和病灶内维生素/维生素衍生物。
UNASSIGNED: Vitamins have gained popularity among physicians and patients for purported benefits to hair, skin, and nail health. Safe and efficacious therapies for nail disorders, many of which are chronic conditions, are needed.
UNASSIGNED: We conducted a literature review of studies assessing the efficacy of oral, topical, and intralesional vitamin/vitamin derivatives for the treatment of nail disorders, including yellow nail syndrome, brittle nail syndrome, onychomycosis, habit-tic nail deformity, periungual/subungual verruca, and nail psoriasis. Forty-nine articles were reviewed. There is good evidence to support the use of topical tazarotene and vitamin D analogs for nail psoriasis treatment. We found overall limited evidence for treatment of other nail disorders with vitamin/vitamin derivatives, and further research is needed to support their use.
UNASSIGNED: Besides topical tazarotene and vitamin D analogs for nail psoriasis treatment, there is limited evidence for treatment of nail disorders with topical, oral, and intralesional vitamin/vitamin derivatives.