Tomography, Spiral Computed

体层摄影术,螺旋计算
  • 文章类型: Journal Article
    目的:通过评估髂骨的厚度和弯曲度,了解髂骨的形态特征,为髂骨瓣重建颌骨提供建议和帮助。
    方法:本研究纳入了在2020年至2022年之间在手术前进行腹部区域螺旋CT检查的100例患者。创建髂骨的3D重建图像。沿着髂棘的中心线(VP2~VP10)每2cm制作5个垂直于髂棘的垂直平面。在这些垂直平面上,沿髂骨的长轴(D1~D4)每1cm做4条垂直线。这些地点的厚度,测量髂骨的水平角(HA)以及拐点与前上棘中心点(DIA)之间的距离。
    结果:在VP6〜VP10的D1〜D4和D3和D4的VP2〜VP10的水平上,髂骨厚度显着降低(P<0.05)。髂峰HA为149.13±6.92°,DIA为7.36±1.01cm。髂骨厚度,HA和DIA与患者年龄的相关性非常弱或弱,身高和体重。
    结论:髂棘平均厚度从前到后大致减少,从上到下。髂棘的厚度和曲率很难按年龄预测,身高和体重。
    结论:在颌骨重建手术前建议采用虚拟手术计划,而髂棘突走向肺泡突可能是更好的选择。
    OBJECTIVE: to understand the morphological characteristics of iliac crest and provide advice and assistance for jaw bone reconstruction with iliac bone flap by evaluating the thickness and curvature of iliac crest.
    METHODS: 100 patients who had taken Spiral CT of the Abdominal region before surgeries between 2020 and 2022 were included in this study. 3D reconstruction images of the iliac bones were created. 5 vertical planes perpendicular to the iliac crest were made every 2 cm along the centerline of the iliac crest (VP2 ~ VP10). On these vertical planes, 4 perpendicular lines were made every 1 cm along the long axis of the iliac crest (D1 ~ D4). The thicknesses at these sites, horizontal angle (HA) of iliac crest and the distance between inflection point and the central point of anterior superior iliac spine (DIA) were measured.
    RESULTS: The thickness of iliac bone decreased significantly from D1 ~ D4 on VP6 ~ VP10 and from VP2 ~ VP10 on D3 and D4 level (P<0.05). HA of iliac crests was 149.13 ± 6.92°, and DIA was 7.36 ± 1.01 cm. Iliac bone thickness, HA and DIA had very weak or weak correlation with patient\'s age, height and weight.
    CONCLUSIONS: The average thicknesses of iliac crest were decreased approximately from front to back, from top to bottom. The thickness and curvature of the iliac crest were difficult to predict by age, height and weight.
    CONCLUSIONS: Virtual surgical planning is recommended before jaw bone reconstruction surgery with iliac bone flap, and iliac crest process towards alveolar process might be a better choice.
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  • 文章类型: Journal Article
    目的:本研究利用临床和多层螺旋CT(MSCT)特征开发并验证了列线图,用于预测IA期肺腺癌中Ki-67的表达。此外,我们评估了Ki-67表达水平的预测准确性,根据我们的模型,评估IA期肺腺癌的预后。
    方法:我们回顾性分析395例经病理证实的IA期肺腺癌患者的资料。共有322名患者以6:4的比例分为训练组和内部验证组,而其余73例患者组成外部验证组.根据病理结果,将患者分为Ki-67标记指数(LI)高、低组.对临床和CT特征进行统计分析。训练组用于通过逻辑回归构建预测模型并制定列线图。评估了列线图的预测能力和拟合优度。进行了内部和外部验证,并对临床效用进行了评估。最后,比较无复发生存率(RFS).
    结果:在训练组中,性别,年龄,肿瘤密度类型,肿瘤-肺界面,分叶,刺突,胸膜凹陷,Ki-67LI高和低的患者之间的最大结节直径显着不同。多因素Logistic回归分析显示,性别,肿瘤密度,在IA期肺腺癌中,最大结节直径与Ki-67高表达显着相关。校准曲线与标准曲线非常相似,表明该模型具有良好的鉴别力和准确性。决策曲线分析显示出良好的临床实用性。列线图预测的高Ki-67LI患者的RFS较差。
    结论:利用临床和CT特征预测IA期肺腺癌中Ki-67表达的列线图表现优异,临床效用,和预后意义,这表明该列线图是一种用于术前预测Ki-67表达的非侵入性个性化方法。
    OBJECTIVE: This study developed and validated a nomogram utilizing clinical and multi-slice spiral computed tomography (MSCT) features for the preoperative prediction of Ki-67 expression in stage IA lung adenocarcinoma. Additionally, we assessed the predictive accuracy of Ki-67 expression levels, as determined by our model, in estimating the prognosis of stage IA lung adenocarcinoma.
    METHODS: We retrospectively analyzed data from 395 patients with pathologically confirmed stage IA lung adenocarcinoma. A total of 322 patients were divided into training and internal validation groups at a 6:4 ratio, whereas the remaining 73 patients composed the external validation group. According to the pathological results, the patients were classified into high and low Ki-67 labeling index (LI) groups. Clinical and CT features were subjected to statistical analysis. The training group was used to construct a predictive model through logistic regression and to formulate a nomogram. The nomogram\'s predictive ability and goodness-of-fit were assessed. Internal and external validations were performed, and clinical utility was evaluated. Finally, the recurrence-free survival (RFS) rates were compared.
    RESULTS: In the training group, sex, age, tumor density type, tumor-lung interface, lobulation, spiculation, pleural indentation, and maximum nodule diameter differed significantly between patients with high and low Ki-67 LI. Multivariate logistic regression analysis revealed that sex, tumor density, and maximum nodule diameter were significantly associated with high Ki-67 expression in stage IA lung adenocarcinoma. The calibration curves closely resembled the standard curves, indicating the excellent discrimination and accuracy of the model. Decision curve analysis revealed favorable clinical utility. Patients with a nomogram-predicted high Ki-67 LI exhibited worse RFS.
    CONCLUSIONS: The nomogram utilizing clinical and CT features for the preoperative prediction of Ki-67 expression in stage IA lung adenocarcinoma demonstrated excellent performance, clinical utility, and prognostic significance, suggesting that this nomogram is a noninvasive personalized approach for the preoperative prediction of Ki-67 expression.
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  • 文章类型: Journal Article
    背景:目前很少有报告使用不同的计算机断层扫描(CT)扫描仪比较具有40毫米检测器宽度的螺旋扫描和具有160毫米检测器宽度的轴向扫描之间的场透镜剂量。
    目的:在儿科胸部检查中使用不同的CT扫描仪时,比较40毫米探测器宽度的螺旋扫描和160毫米探测器宽度的轴向扫描之间的晶状体散射剂量。
    方法:使用了两种不同的CT机:RevolutionCT(GEHealthcare,Waukesha,WI),256行,0.625毫米多探测器;和AquilionONEGENESIS版(佳能医疗系统,Otawara,日本)有320排,0.5毫米多探测器。使用了三个小儿拟人化体模,光学刺激发光剂量计(OSLD)放置在左和右透镜。在儿科胸部CT检查期间,在40毫米检测器宽度的螺旋扫描和160毫米检测器宽度的轴向扫描之间比较了OSLD测得的散射剂量值。
    结果:新生儿螺旋扫描和轴向扫描的等效剂量中位数分别为0.12和0.12mSv/mGy,1岁儿童的0.17和0.16mSv/mGy,5岁儿童为0.18和0.15mSv/mGy,分别,使用革命CT时。随着革命CT,在新生儿和1岁体模的螺旋扫描和轴向扫描之间,散射剂量没有观察到显著差异.然而,在5岁体模中,螺旋扫描的晶状体散射剂量比轴向扫描高约20-35%(P<0.01)。新生儿的螺旋扫描和轴向扫描的晶状体等效剂量中位数为0.12和0.07mSv/mGy,1岁儿童的0.07和0.05mSv/mGy,5岁儿童为0.14和0.12mSv/mGy,分别,当使用AquilionONE时。有了AquilionONE,螺旋扫描的晶状体散射剂量约为70%,40%,新生儿高30%,1岁,和5岁的幻影,分别,轴向扫描(P<0.01)。
    结论:使用AquilionONE时,在所有三个体模中,螺旋扫描的晶状体散射剂量均显着高于轴向扫描。相比之下,当使用革命CT时,5岁体模的螺旋扫描的晶状体散射剂量明显高于轴向扫描。这些结果表明,尽管分散的剂量可能因CT扫描仪和身体大小而有所不同,在轴向扫描的情况下,它们通常较低。
    BACKGROUND: Reports comparing field lens doses between helical scans with a 40-mm detector width and axial scans with a 160-mm detector width using different computed tomography (CT) scanners are currently scarce.
    OBJECTIVE: To compare scatter doses for lenses between a helical scan with a 40-mm detector width and an axial scan with a 160-mm detector width when using different CT scanners in the context of pediatric chest examinations.
    METHODS: Two different CT machines were used: Revolution CT (GE Healthcare, Waukesha, WI) with a 256-row, 0.625-mm multidetector; and Aquilion ONE GENESIS Edition (Canon Medical Systems, Otawara, Japan) with a 320-row, 0.5-mm multidetector. Three pediatric anthropomorphic phantoms were used, with optically stimulated luminescence dosimeters (OSLDs) placed on the left and right lenses. The scatter dose values measured by the OSLDs were compared between a helical scan with a 40-mm detector width and an axial scan with a 160-mm detector width during pediatric chest CT examinations.
    RESULTS: Median equivalent doses for the helical and axial scans were 0.12 and 0.12 mSv/mGy for the newborn, 0.17 and 0.16 mSv/mGy for the 1-year-old, and 0.18 and 0.15 mSv/mGy for the 5-year-old, respectively, when using the Revolution CT. With the Revolution CT, no significant differences were observed in the scatter doses between helical and axial scans in the newborn and 1-year-old phantoms. However, the lens scatter dose for the helical scan was approximately 20-35% higher than that for the axial scan in the 5-year-old phantom (P<0.01). The median equivalent doses of eye lenses for the helical and axial scans were 0.12 and 0.07 mSv/mGy for the newborn, 0.07 and 0.05 mSv/mGy for the 1-year-old, and 0.14 and 0.12 mSv/mGy for the 5-year-old, respectively, when using the Aquilion ONE. With the Aquilion ONE, lens scatter doses for the helical scan were approximately 70%, 40%, and 30% higher in the newborn, 1-year-old, and 5-year-old phantoms, respectively, than those for the axial scan (P<0.01).
    CONCLUSIONS: When using the Aquilion ONE, lens scatter doses for the helical scan were significantly higher in all three phantoms than those for the axial scan. In contrast, when using the Revolution CT, the lens scatter dose for the helical scan was significantly higher in the 5-year-old phantom than that for the axial scan. These results suggest that although scattered doses may vary with respect to the CT scanner and body size, they are generally lower in the case of axial scans.
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  • 文章类型: Journal Article
    在耳鼻咽喉科中,需要精确和智能地评估中耳结构的复杂性,以诊断与耳鼻咽喉科有关的疾病。由于解剖细节的复杂性和各种疾病的病因,如创伤,慢性中耳炎,和先天性异常,传统的诊断程序可能无法产生准确的诊断。这项研究旨在通过将高分辨率螺旋计算机断层扫描(HRSCT)扫描与深度学习技术(DLT)相结合来增强耳颞区和小骨疾病的诊断。这项研究采用了一种深度学习方法,卷积神经网络-UNet(CNN-UNet),从医学照片中提取亚像素信息。这种方法为医生和研究人员提供了尖端资源,导致突破性的发现和更好的患者医疗保健。研究工作是CNN-UNet模型和高分辨率计算机断层扫描(CT)扫描之间的相互作用,自动化活动,包括小骨分割,裂缝检测,和中断导致分类,加快诊断过程,增加临床决策。建议的HRSCT-DLT模型代表了高分辨率螺旋CT扫描与CNN-UNet模型的集成,经过微调,以解决耳廓颞骨和听骨疾病的细微差别。这种新颖的组合提高了诊断效率和我们对这些复杂疾病的整体理解。这项研究的结果突出了将高分辨率CT扫描与CNN-UNet模型结合在耳鼻喉科的前景,为更准确的诊断和更个性化的治疗计划铺平了道路,为患者经历耳颞骨和小骨相关的破坏。
    Precision and intelligence in evaluating the complexities of middle ear structures are required to diagnose auriculotemporal and ossicle-related diseases within otolaryngology. Due to the complexity of the anatomical details and the varied etiologies of illnesses such as trauma, chronic otitis media, and congenital anomalies, traditional diagnostic procedures may not yield accurate diagnoses. This research intends to enhance the diagnosis of diseases of the auriculotemporal region and ossicles by combining High-Resolution Spiral Computed Tomography (HRSCT) scanning with Deep Learning Techniques (DLT). This study employs a deep learning method, Convolutional Neural Network-UNet (CNN-UNet), to extract sub-pixel information from medical photos. This method equips doctors and researchers with cutting-edge resources, leading to groundbreaking discoveries and better patient healthcare. The research effort is the interaction between the CNN-UNet model and high-resolution Computed Tomography (CT) scans, automating activities including ossicle segmentation, fracture detection, and disruption cause classification, accelerating the diagnostic process and increasing clinical decision-making. The suggested HRSCT-DLT model represents the integration of high-resolution spiral CT scans with the CNN-UNet model, which has been fine-tuned to address the nuances of auriculotemporal and ossicular diseases. This novel combination improves diagnostic efficiency and our overall understanding of these intricate diseases. The results of this study highlight the promise of combining high-resolution CT scanning with the CNN-UNet model in otolaryngology, paving the way for more accurate diagnosis and more individualized treatment plans for patients experiencing auriculotemporal and ossicle-related disruptions.
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  • 文章类型: Journal Article
    目的:使用手和旋转器械比较乳牙的根管体积,并使用螺旋计算机断层扫描(SCT)评估根管填充技术和根管闭塞材料在器械后根管体积中的流量。
    方法:将新鲜提取的16颗初级磨牙随机分为两组,并在插入前后进行SCT分析。对于手动技术(I组),使用K文件准备了八颗牙齿,用ProTaper文件进行旋转(第二组)八颗牙齿预备。使用SCT测量每个管道中的填充体积,并计算闭塞体积的百分比。数据采用Mann-WhitneyU检验进行统计分析。
    结果:两组根管体积扩大有统计学意义。即使K文件和ProTaper系统在仪器使用后都带来了扩大的运河,在两条运河中使用K文件后,体积有统计学上的显着增加。在三条运河中,使用ProTaper后,体积有统计学上的显着增加。不管使用的闭塞技术和材料,闭塞后体积无统计学差异。
    结论:从这项研究的结果来看,ProTaper文件系统显示合适的体积放大到最佳水平,这是根管根管的主要部位所需要的,在运河塑造方面更好,良好的闭塞后体积证明。
    结论:使用手动不锈钢文件清洁和塑造恒牙根管的传统方法会导致根管形态出现不良弯曲,使正确填充根管困难。这也是耗时的,有时会导致医源性错误。已经开发了旋转镍-钛(Ni-Ti)仪器技术来克服这些问题。如何引用这篇文章:YadavDBUC,VarmaRB,KumarJS,etal.手动和旋转仪器的体积分析,根管充填技术,使用螺旋CT在原发性牙齿中的填充材料。JContempDentPract2024;25(3):250-259。
    OBJECTIVE: To compare the root canal volume in primary teeth using hand and rotary instruments and to evaluate root canal filling techniques and flow of root canal obturation materials in the postinstrumented root canal volume using spiral computed tomography (SCT).
    METHODS: Freshly extracted 16 primary molars were randomly divided into two groups and subjected to SCT analysis before and after instrumentation. For the manual technique (group I) with eight teeth were prepared using K files, and rotary (group II) eight teeth preparation was performed with ProTaper files. The filled volume in each canal was measured using SCT, and the percentage of obturated volume was calculated. The data were statistically analyzed using the Mann-Whitney U test.
    RESULTS: There was a statistically significant difference in both groups\' volume of root canals enlarged. Even though both K files and the ProTaper system brought about enlarged canals after instrumentation, there was a statistically significant increase in volume after using K files in two canals. In three canals, there was a statistically significant increase in volume after using ProTaper. Irrespective of the obturation technique and materials used, there is no statistically significant difference in the volume after obturation.
    CONCLUSIONS: From the results of this study, the ProTaper file system shows suitable volumetric enlargement up to an optimum level, which is needed in primary root canal walls, and is better in canal shaping, as evidenced by good postobturation volume.
    CONCLUSIONS: The traditional method of cleaning and shaping the root canals in permanent teeth using manual stainless-steel files can lead to undesirable curvatures in root canal morphology, making correctly filling the root canals difficult. It is also time-consuming and sometimes leads to iatrogenic errors. Rotary nickel-titanium (Ni-Ti) instrumentation techniques have been developed to overcome these problems. How to cite this article: Yadav DBUC, Varma RB, Kumar JS, et al. Volumetric Analysis of Hand and Rotary Instrumentation, Root Canal Filling Techniques, and Obturation Materials in Primary Teeth Using Spiral CT. J Contemp Dent Pract 2024;25(3):250-259.
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  • 文章类型: Journal Article
    随着低剂量螺旋计算机断层扫描(LDCT)的广泛使用以及对个人健康的认识不断提高,肺结节检出率稳步上升。
    评估两种不同模型的Hook-Wire针定位程序对肺小结节活检的成功率和安全性。回顾性分析
    94例,共97个肺小结节行穿刺活检。将病例分为两组:A组,使用乳房定位针钢丝(BardHealthcareScienceCo.,有限公司);B组,使用一次性肺结节穿刺针(SensCureBiotechnologyCo.,有限公司)。所有患者在定位和活检后的同一天接受电视胸腔镜手术(VATS)进行结节切除。穿刺定位操作时间,成功率,并发症如肺出血,气胸,咯血,术后舒适度进行观察比较。
    在A组中,97个结节的平均定位手术时间为15.47±5.31分钟,成功率为94.34%。并发症发生率为71.69%(气胸12例,肺出血35例,咯血2例),并报告了40例定位后不适。B组,平均定位手术时间为25.32±7.83分钟,成功率100%。并发症发生率为29.55%(气胸3例,15例肺出血,咯血0例),3例报告术后不适。根据本研究的数据分析,B组穿刺相关并发症发生率低于A组,随着更高的成功率和明显更大的术后舒适度。
    一次性肺结节穿刺针在肺小结节定位活检中更安全有效,与乳房定位针相比,舒适度增加。此外,并发症发生率明显降低。
    UNASSIGNED: With the widespread use of low-dose spiral computed tomography (LDCT) and increasing awareness of personal health, the detection rate of pulmonary nodules is steadily rising.
    UNASSIGNED: To evaluate the success rate and safety of two different models of Hook-Wire needle localization procedures for pulmonary small nodule biopsy.
    UNASSIGNED: Ninety-four cases with a total of 97 pulmonary small nodules undergoing needle localization biopsy were retrospectively analyzed. The cases were divided into two groups: Group A, using breast localization needle steel wire (Bard Healthcare Science Co., Ltd.); Group B, using disposable pulmonary nodule puncture needle (SensCure Biotechnology Co., Ltd.). All patients underwent video-assisted thoracoscopic surgery (VATS) for nodule removal on the same day after localization and biopsy. The puncture localization operation time, success rate, complications such as pulmonary hemorrhage, pneumothorax, hemoptysis, and postoperative comfort were observed and compared.
    UNASSIGNED: In Group A, the average localization operation time for 97 nodules was 15.47 ± 5.31 minutes, with a success rate of 94.34%. The complication rate was 71.69% (12 cases of pneumothorax, 35 cases of pulmonary hemorrhage, 2 cases of hemoptysis), and 40 cases of post-localization discomfort were reported. In Group B, the average localization operation time was 25.32 ± 7.83 minutes, with a 100% success rate. The complication rate was 29.55% (3 cases of pneumothorax, 15 cases of pulmonary hemorrhage, 0 cases of hemoptysis), and 3 cases reported postoperative discomfort. According to the data analysis in this study, Group B had a lower incidence of puncture-related complications than Group A, along with a higher success rate and significantly greater postoperative comfort.
    UNASSIGNED: The disposable pulmonary nodule puncture needle is safer and more effective in pulmonary small nodule localization biopsy, exhibiting increased comfort compared to the breast localization needle. Additionally, the incidence of complications is significantly lower.
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  • 文章类型: Journal Article
    这项实验研究的目的是量化螺距和机架旋转时间对超高分辨率光子计数CT(UHR-PCCT)中图像质量和文件大小的影响。颈椎和腰椎,骨盆,对两个新鲜冷冻尸体标本的上肢进行了9种剂量匹配的UHR-PCCT扫描方案,采用120×0.2mm的准直,不同的间距(0.3/1.0/1.2)和旋转时间(0.25/0.5/1.0s)。由五名放射科医生独立分析图像质量,并通过放置标准化的感兴趣区域以记录平均信号衰减和噪声来进一步证实。有效的MA,CT剂量指数(CTDIvol),特定尺寸剂量估计(SSDE),扫描持续时间,和原始数据文件大小进行了比较。不管解剖区域如何,试验方案中CTDIvol(p≥0.204)和SSDE(p≥0.240)无显著差异.虽然检查持续时间差异很大(所有p≤0.016),高螺距方案的扫描时间最低(4.3±1.0s),低螺距方案的扫描时间最高(43.6±15.4s).高螺距和短机架旋转时间的组合产生了最低的感知图像质量(组内相关系数0.866;95%置信区间0.807-0.910;p<0.001)和最高的噪声。原始数据大小随采集时间增加(15.4±5.0至235.0±83.5GByte;p≤0.013)。旋转时间和音调因子对UHR-PCCT中的图像质量有相当大的影响,因此必须针对不同的肌肉骨骼成像任务进行精心选择。在采集时间较长的考试中,原始数据大小大幅增加,因此限制了较大扫描量的临床适用性。
    The goal of this experimental study was to quantify the influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting CT (UHR-PCCT). Cervical and lumbar spine, pelvis, and upper legs of two fresh-frozen cadaveric specimens were subjected to nine dose-matched UHR-PCCT scan protocols employing a collimation of 120 × 0.2 mm with varying pitch (0.3/1.0/1.2) and rotation time (0.25/0.5/1.0 s). Image quality was analyzed independently by five radiologists and further substantiated by placing normed regions of interest to record mean signal attenuation and noise. Effective mAs, CT dose index (CTDIvol), size-specific dose estimate (SSDE), scan duration, and raw data file size were compared. Regardless of anatomical region, no significant difference was ascertained for CTDIvol (p ≥ 0.204) and SSDE (p ≥ 0.240) among protocols. While exam duration differed substantially (all p ≤ 0.016), the lowest scan time was recorded for high-pitch protocols (4.3 ± 1.0 s) and the highest for low-pitch protocols (43.6 ± 15.4 s). The combination of high helical pitch and short gantry rotation times produced the lowest perceived image quality (intraclass correlation coefficient 0.866; 95% confidence interval 0.807-0.910; p < 0.001) and highest noise. Raw data size increased with acquisition time (15.4 ± 5.0 to 235.0 ± 83.5 GByte; p ≤ 0.013). Rotation time and pitch factor have considerable influence on image quality in UHR-PCCT and must therefore be chosen deliberately for different musculoskeletal imaging tasks. In examinations with long acquisition times, raw data size increases considerably, consequently limiting clinical applicability for larger scan volumes.
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  • 文章类型: Journal Article
    目的:本研究旨在将机器学习技术与影像组学方法一起使用,从螺旋计算机断层扫描(CT)图像中建立术前预测诊断模型。该模型旨在用于常见颌骨囊性病变的鉴别诊断。
    方法:回顾性,病例对照研究。
    方法:本回顾性研究在中山大学孙逸仙纪念医院(广州,广东,中国)。用于建立预测诊断模型的所有数据均来自160名患者,2019年至2023年在中山大学孙逸仙纪念医院口腔颌面外科接受治疗。
    方法:本研究共纳入160名患者。我们从每位患者的CT扫描图像中提取了107个影像组学特征。在特征选择过程之后,我们选择了其中15个影像学特征来构建预测诊断模型.
    结果:在使用3种不同的机器学习方法(支持向量机,随机森林[RF],和多变量逻辑回归),RF模型显示出最佳的预测性能。它的灵敏度为0.923,特异性为0.643,准确性为0.825,接收器工作特征曲线下面积为0.810。
    结论:术前预测模型,基于螺旋CT影像组学和机器学习算法,显示出有希望的鉴别诊断能力。对于常见的颌骨囊性病变,该预测模型具有潜在的临床应用价值,为治疗决策提供科学参考。
    OBJECTIVE: This study aims to use machine learning techniques together with radiomics methods to build a preoperative predictive diagnostic model from spiral computed tomography (CT) images. The model is intended for the differential diagnosis of common jaw cystic lesions.
    METHODS: Retrospective, case-control study.
    METHODS: This retrospective study was conducted at Sun Yat-sen Memorial Hospital of Sun Yat-sen University (Guangzhou, Guangdong, China). All the data used to build the predictive diagnostic model were collected from 160 patients, who were treated at the Department of Oral and Maxillofacial Surgery at Sun Yat-sen Memorial Hospital of Sun Yat-sen University between 2019 and 2023.
    METHODS: We included a total of 160 patients in this study. We extracted 107 radiomic features from each patient\'s CT scan images. After a feature selection process, we chose 15 of these radiomic features to construct the predictive diagnostic model.
    RESULTS: Among the preoperative predictive diagnostic models built using 3 different machine learning methods (support vector machine, random forest [RF], and multivariate logistic regression), the RF model showed the best predictive performance. It demonstrated a sensitivity of 0.923, a specificity of 0.643, an accuracy of 0.825, and an area under the receiver operating characteristic curve of 0.810.
    CONCLUSIONS: The preoperative predictive model, based on spiral CT radiomics and machine learning algorithms, shows promising differential diagnostic capabilities. For common jaw cystic lesions, this predictive model has potential clinical application value, providing a scientific reference for treatment decisions.
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  • 文章类型: English Abstract
    Objective: To evaluate the relationships between the location and extent of diffusion of free intraperitoneal air by multi-slice spiral CT (MSCT) and between the location and size of acute gastrointestinal perforation. Methods: This was a descriptive case series. We examined abdominal CT images of 33 patients who were treated for intraoperatively confirmed gastrointestinal perforation (excluding appendiceal perforation) in the Department of General Surgery, Nanfang Hospital between January and September 2022. We identified five locations of intraperitoneal air: the subphrenic space, hepatic portal space, mid-abdominal wall, mesenteric space, and pelvic cavity. We allocated the 33 patients to an upper gastrointestinal perforation (n=23) and lower gastrointestinal perforation group (n=10) base on intraoperative findings and analyzed the relationships between the locations of free gas and of gastrointestinal perforation. Additionally, we established two models for analyzing the extent of diffusion of free gas in the abdominal cavity and constructed receiver operating characteristic (ROC) curves to analyze the relationships between the two models and the size of the gastrointestinal perforation. Results: In the upper gastrointestinal perforation group, free gas was located around the hepatic portal area in 91.3% (21/23) of patients: this is a significantly greater proportion than that found in the lower gastrointestinal perforation group (5/10) (P=0.016). In contrast, free gas was located in the mesenteric interspace in 8/10 patients in the lower gastrointestinal perforation group; this is a significantly greater proportion than was found in the upper gastrointestinal perforation group (8.7%, 2/23) (P<0.010). The sensitivity of diagnosis of upper gastrointestinal perforation base on the presence of hepatic portal free gas was 84.8% and the specificity 71.4%. Further, the sensitivity of diagnosis of lower gastrointestinal perforation base on the presence of mesenteric interspace free gas was 80.0% and the specificity 91.3%. The rates of presence of free gas in the subdiaphragmatic area, mid-abdominal wall, and pelvic cavity did not differ significantly between the two groups (all P>0.05). Receiver operating characteristic curves showed that when free gas was present in four or more of the studied locations in the abdominal cavity, the optimal cutoff for perforation diameter was 2 cm, the corresponding sensitivity 66.7%, and the specificity 100%, suggesting that abdominal free gas diffuses extensively when the diameter of the perforation is >2 cm. Another model revealed that when free gas is present in three or more of the studied locations, the optimal cutoff for perforation diameter is 1 cm, corresponding to a sensitivity of 91.7% and specificity of 76.2%; suggesting that free gas is relatively confined in the abdominal cavity when the diameter of the perforation is <1 cm. Conclusion: Identifying which of five locations in the abdominal cavity contains free intraperitoneal air by examining MSCT images can be used to assist in the diagnosis of the location and size of acute gastrointestinal perforations.
    目的: 探讨多层螺旋CT显示腹腔游离气体位置及弥散程度与急性消化道穿孔部位及大小的关系。 方法: 本研究采用描述性病例系列研究方法。分析南方医院普通外科2022年1—9月期间,33例经手术证实的消化道穿孔患者(阑尾穿孔除外)的腹部CT图像,将腹腔游离气体位置分为5个部位,即膈下、肝门、中腹壁、肠系膜间和盆腔。按手术探查结果,将33例患者分为上消化道穿孔组(23例)和下消化道穿孔组(10例),分析不同位置的腹腔游离气体与消化道穿孔部位的关系。另外,通过观察腹腔内游离气体的弥散程度,建立两个分析模型,利用受试者工作特征(ROC)曲线分析两种模型与消化道穿孔大小的关系。 结果: 上消化道穿孔组中,有91.3%(21/23)可观察到肝门部游离气体,高于下消化道穿孔组(5/10),差异有统计学意义(P=0.016);而下消化道穿孔组中,有8/10可观察到肠系膜间游离气体,高于上消化道穿孔组(8.7%,2/23),差异有统计学意义(P<0.010)。肝门部游离气体诊断上消化道穿孔的灵敏度为84.8%,特异度为71.4%;肠系膜间游离气体诊断下消化道穿孔的灵敏度为80.0%,特异度为91.3%。两组观察到膈下、中腹壁和盆腔游离气体的差异无统计学意义(均P>0.05)。ROC曲线显示,当腹腔内出现4个或以上部位游离气体时,穿孔直径最佳截断值为2 cm,对应灵敏度为66.7%,特异度为100%;提示穿孔直径>2 cm时,腹腔游离气体高度弥散。当腹腔内出现3个或以上部位游离气体时,穿孔直径最佳截断值为1 cm,对应灵敏度为91.7%,特异度为76.2%;提示穿孔直径<1 cm时,腹腔游离气体相对局限。 结论: 腹腔游离气体五分法可帮助诊断急性消化道穿孔的定位和大小。.
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  • 文章类型: Journal Article
    我们的研究旨在评估改良的患者特异性手术指南辅助的单侧粉碎性腋窝复合体(ZMC)骨折的精确治疗方法。回顾性非随机研究是在中国一家医院进行的。回顾性分析2018年1月1日至2022年12月31日诊断为单侧粉碎性ZMC骨折的所有患者。所有患者术前均行螺旋计算机断层扫描(CT)。使用DICOM格式的软件处理CT数据,并将其转移到ProplanCMF3.0进行术前虚拟手术计划和术后评估。所有数据均从标准化电子病历中提取。所有统计分析均使用SPSS20.0版进行。统计分析采用卡方检验和t检验。纳入的54例患者分为两组,27名患者的相等队列,并随访至少6个月。在引导组中使用改良的针对患者的手术引导辅助骨折复位(23名男性,4名女性;平均年龄37.74±12.07岁),对照组中没有改良的患者专用手术指南(20名男性,7名女性;平均年龄37.44±13.58岁)。在指南组中,受影响侧和未受影响侧之间的平均隆起偏差为1.01±0.92mm,患侧和未患侧之间的平均宽度偏差为1.29±1.32mm。在对照组中,受影响侧和未受影响侧之间的平均隆起偏差为1.99±1.69mm,患侧和未患侧之间的平均宽度偏差为2.68±2.01mm。两组患侧与健康侧面部前凸(p=0.001)和宽度对称(p=0.003)差异均有统计学意义(p<0.05)。总之,将改良的针对患者的手术指南应用于单侧粉碎性腋窝复合体骨折复位术具有更大的可预测性和有效性,改善了双边ZMC对称性。应当注意,这种方法对于经验不足的外科医生将是特别有益的。
    Our study aimed to evaluate modified patient-specific surgical-guide-assisted precise treatment of unilateral comminuted zygomaticomaxillary complex (ZMC) fractures. The retrospective non-randomized study was conducted in a single hospital in China. All patients diagnosed with unilateral comminuted ZMC fractures between January 1, 2018 and December 31, 2022 were retrospectively reviewed. All patients underwent preoperative spiral computed tomography (CT). CT data were processed using software to DICOM format and transferred to Proplan CMF3.0 for preoperative virtual surgical planning and postoperative evaluation. All data were extracted from standardized electronic medical records. All statistical analyses were performed using SPSS version 20.0. The chi-square test and t-test were used for statistical analyses. The 54 included patients were divided into two comparable, equal cohorts of 27 patients, and followed up for at least 6 months. Fracture reduction was assisted using the modified patient-specific surgical guides in the guide group (23 males, four females; mean age 37.74 ± 12.07 years) and without the modified patient-specific surgical guides in the control group (20 males, seven females; mean age 37.44 ± 13.58 years). In the guide group, the mean eminence deviation between the affected and unaffected sides was 1.01 ± 0.92 mm, and the mean width deviation between the affected and unaffected sides was 1.29 ± 1.32 mm. In the control group, the mean eminence deviation between the affected and unaffected sides was 1.99 ± 1.69 mm, and the mean width deviation between the affected and unaffected sides was 2.68 ± 2.01 mm. The differences in facial protrusion (p = 0.001) and width (p = 0.003) symmetry between the affected and healthy sides of the two groups were statistically significant (p < 0.05). In conclusion, applying the modified patient-specific surgical guides to unilateral comminuted zygomaticomaxillary complex fracture reduction has the advantages of greater predictability and effectiveness, and improved bilateral ZMC symmetry. It should be noted that this approach would be especially beneficial for less-experienced surgeons.
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