背景:关于水烟吸烟对健康影响的研究仍然不足,尽管它已被证明会通过增加不同类型癌症的危害而危害人类健康,感染,和心血管疾病。我们旨在研究双重吸烟(水烟和香烟)对不育男性精液参数的影响。
方法:在这项横断面研究中,我们在访问IVF实验室进行精液分析(SFA)的男性中,研究了不同类型吸烟模式对人类精液参数的影响.包括761名参与者,分为:108名双重吸烟者,219名水烟吸烟者,222名吸烟者,212名不吸烟者。分析双重吸烟对正常形态的影响,使用了香烟指数和水烟指数之间的相互作用项。
结果:调整年龄后的多元回归分析,BMI,教育水平,孩子们,慢性疾病,精索静脉曲张,睾丸手术史,不孕持续时间,和原因显示,非吸烟者之间的精子浓度和进行性运动百分比没有显着差异,吸烟者,或水烟吸烟者。然而,三组正常形态百分比的对数差异有统计学意义。吸烟和水烟与较低的正常形态百分比显着相关。对数正常形态%有显著差异,轻度和重度双重吸烟者的对数正常形态%的指数β最小,0.43(95%CI:0.33-0.55)和0.36(95%CI:0.24-0.53),分别。
结论:双重吸烟会对精子形态产生不利影响。
BACKGROUND: The research regarding the effect of hookah smoking on health is still deficient, even though it has been proven to jeopardize human health by raising the hazard of different types of cancers, infections, and cardiovascular disease. We aimed to study the effect of dual tobacco smoking (hookah and cigarettes) on semen parameters of infertile men.
METHODS: In this cross-sectional study, we studied the effect of different types of smoking patterns on human semen parameters among men who visited IVF laboratories to do a seminal fluid analysis (SFA). A total number of 761 participants were included, divided into the following: 108 dual smokers, 219 hookah smokers, 222 cigarette smokers, and 212 non-smokers. To analyze the effect of dual smoking on normal morphology, an interaction term between the cigarette index and hookah index was used.
RESULTS: Multivariable regression analysis after adjustment for age, BMI, education level, children, chronic diseases, varicocele, testicular surgery history, infertility duration, and cause revealed no significant difference in the sperm concentration and the percentage of progressive motility between non-smokers, cigarette smokers, or hookah smokers. However, there was a significant difference in the log of normal morphology percentage between the three groups. Cigarette and hookah smoking were significantly associated with having lower percentages of normal morphology. There was a significant difference in the log-normal morphology %, where light and heavy dual smokers had the least exponential beta of log-normal morphology %, 0.43 (95% CI: 0.33-0.55) and 0.36 (95% CI: 0.24-0.53), respectively.
CONCLUSIONS: Dual tobacco smoking can adversely affect sperm morphology.