■尿道下裂是新生儿男性中最常见的先天性异常,仅次于睾丸未降。大多数儿童通过多次手术可以成功修复尿道下裂。术后并发症并不罕见,如尿道皮肤瘘(UCF),肉孔狭窄,和龟头破裂。组织密封剂在尿道下裂修复中的应用可作为额外的缝合线覆盖,并减少术后并发症。然而,尿道成形术中使用密封胶的效果仍不确定。这篇综述旨在了解组织密封剂的使用对尿道成形术的尿道下裂患者的影响。
■该研究是根据系统评价和荟萃分析(PRISMA)指南的首选报告项目报告的。文献在PubMed上搜索,Embase,和Scopus遵循PRISMA准则。搜索是在10月12日进行的,2021年,使用搜索词(\"胶水\"或\"密封剂\"或\"组织胶\"或\"组织密封剂\"或\"组织粘合剂\")和(\"尿道下裂\"或\"尿道瘘皮肤\"或\"尿道修复\"或\"尿道成形术\"或\"尿道下裂\")。
■从所有数据库中进行系统搜索,得出了160篇潜在文章。在全文回顾之后,本研究纳入了8篇文章.所有研究均报道了尿道膀胱瘘并发症。所有研究报告的并发症均为尿道瘘。一些研究还报道了组织水肿和皮瓣相关并发症。组织密封剂在减少肉孔狭窄方面没有显着作用。
■这项系统评价揭示了尿道下裂修复手术中几种类型的组织密封剂的额外益处。尿道下裂修复中尿道成形术缝合线上的纤维蛋白密封剂应用可提供防水覆盖,并可增强手术效果。
UNASSIGNED: Hypospadias was ranked second after undescended testis as the most prevalent congenital abnormality in newborn males. Hypospadias can be successfully repaired through multiple surgeries in the majority of children. Postoperative complications were not rarely seen after surgeries, such as urethrocutaneous fistula (UCF), meatal stenosis, and glans breakdown. Tissue sealant application in hypospadias repair serves as additional suture line coverage and reduces the post surgery complications. However, the effects of sealants usage during urethroplasty are still uncertain. This review aimed to know the effects of tissue sealant usage on patients with hypospadias who undergo urethroplasty.
UNASSIGNED: The study was reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Literature was searched on PubMed, Embase, and Scopus following PRISMA guidelines. The search was conducted on October 12th, 2021, using the search term (\"glue\" OR \"sealants\" OR \"tissue glue\" OR \"tissue sealant\" OR \"tissue adhesive\") AND (\"hypospadias\" OR \"urethrocutaneous fistula\" OR \"urethral repair\" OR \"urethroplasty\" OR \"hypospadiology\").
UNASSIGNED: Systematic searching from all databases resulted in 160 potential articles. After a full-text review, eight articles were included in this study. Urethrocytaneous fistula complication was reported in all studies. The occurrence of complication reported by all studies was urethrocutaneous fistula. Several studies also reported tissue edema and flap-related complications. Tissue sealant had no significant effect in reducing meatal stenosis.
UNASSIGNED: This systematic review revealed additional benefits from several types of tissue sealant in hypospadias repair surgery. Fibrin sealant application over the urethroplasty suture line in hypospadias repair offers a water-proof coverage and may enhance the outcome from the surgery.