种植体周围炎是一种类似牙周炎的炎症性疾病,由牙科植入物表面形成的生物膜引起的。这种炎症可以扩散到骨组织并导致骨丢失。因此,必须抑制牙种植体表面生物膜的形成。因此,这项研究检查了用热和等离子体处理TiO2纳米管对生物膜形成的抑制作用。将商业纯钛样品阳极氧化以形成TiO2纳米管。在400和600°C下进行热处理,使用等离子体发生器(PGS-200,Expantech,水原,大韩民国)。接触角,表面粗糙度,表面结构,晶体结构,和化学成分进行了测量,以分析样品的表面性质。使用两种方法评估生物膜形成的抑制。这项研究的结果表明,TiO2纳米管在400°C下的热处理抑制了变形链球菌的粘附(S。mutans),与最初的生物膜形成有关,并且在600°C下对TiO2纳米管进行热处理会抑制牙龈卟啉单胞菌的粘附(P。牙龈),导致种植体周围炎.对在600°C热处理的TiO2纳米管施加等离子体会抑制变形链球菌和牙龈卟啉单胞菌的粘附。
Peri-implantitis is an inflammatory disease similar to periodontitis, caused by biofilms formed on the surface of dental implants. This inflammation can spread to bone tissues and result in bone loss. Therefore, it is essential to inhibit the formation of biofilms on the surface of dental implants. Thus, this study examined the inhibition of biofilm formation by treating TiO2 nanotubes with heat and plasma. Commercially pure titanium specimens were anodized to form TiO2 nanotubes. Heat treatment was performed at 400 and 600 °C, and atmospheric pressure plasma was applied using a plasma generator (PGS-200, Expantech, Suwon, Republic of Korea). Contact angles, surface roughness, surface structure, crystal structure, and chemical compositions were measured to analyze the surface properties of the specimens. The inhibition of biofilm formation was assessed using two methods. The results of this study showed that the heat treatment of TiO2 nanotubes at 400 °C inhibited the adhesion of Streptococcus mutans (S. mutans), associated with initial biofilm formation, and that heat treatment of TiO2 nanotubes at 600 °C inhibited the adhesion of Porphyromonas gingivalis (P. gingivalis), which causes peri-implantitis. Applying plasma to the TiO2 nanotubes heat-treated at 600 °C inhibited the adhesion of S. mutans and P. gingivalis.