Thoracic injury

胸部损伤
  • 文章类型: Journal Article
    背景:虽然胸部X线检查(CXR)是快速检测危及生命的伤害的有效工具,胸部计算机断层扫描(CCT)更敏感,尽管增加了时间,成本,和辐射。到目前为止,目前证据有限,对最佳成像实践缺乏共识.我们试图确定孤立性钝性胸外伤的成像方式与结果之间的关联。
    方法:在2017-2020年TQIP数据库中查询了在入院后24小时内遭受孤立性钝性胸部创伤并接受胸部影像学检查的成年患者。接受CCT的患者与接受CXR的患者的倾向评分为2:1。主要结果是死亡率,次要结局是住院和ICU住院时间(LOS),入住ICU,需要和需要机械通风的天数,并发症,和排放位置。
    结果:倾向评分匹配产生了17.716名CCT患者和8861名CXR患者。而双变量分析显示24小时较低(CCT.2%vsCXR.4%,P=.0015)和住院死亡率(CCT1.2%vsCXR1.5%,P=.0454)在CCT组中,组间生存概率无差异(P=.1045)。CCT患者进入ICU的比例更高(CCT26.9%vsCXR21.9%,P<.0001)并出院至康复中心(CCT.8%vsCXR.5%,P=.0178)。
    结论:CT在孤立的钝性胸部创伤中没有比CXR的生存获益。虽然如果临床上不清楚,应考虑CCT,CXR可能足以作为初始筛选工具。这些发现有助于在受限环境中进行最佳资源分配。
    BACKGROUND: While chest X-ray (CXR) is an efficient tool for expeditious detection of life-threatening injury, chest computed tomography (CCT) is more sensitive albeit with added time, cost, and radiation. Thus far, there is limited evidence and lack of consensus on the best imaging practices. We sought to determine the association between imaging modality and outcomes in isolated blunt thoracic trauma.
    METHODS: The 2017-2020 TQIP database was queried for adult patients who sustained isolated blunt chest trauma and underwent chest imaging within 24 hours of admission. Patients who underwent CCT were 2:1 propensity-score-matched to those who underwent CXR. The primary outcome was mortality, and the secondary outcomes were hospital and ICU length of stay (LOS), ICU admission, need for and days requiring mechanical ventilation, complications, and discharge location.
    RESULTS: Propensity score matching yielded 17 716 patients with CCT and 8861 with CXR. While bivariate analysis showed lower 24-hr (CCT .2% vs CXR .4%, P = .0015) and in-hospital mortality (CCT 1.2% vs CXR 1.5%, P = .0454) in the CCT group, there was no difference in survival probability between groups (P = .1045). A higher percentage of CCT patients were admitted to the ICU (CCT 26.9% vs CXR 21.9%, P < .0001) and discharged to rehab (CCT .8% vs CXR .5%, P = .0178).
    CONCLUSIONS: CT offers no survival benefit over CXR in isolated blunt thoracic trauma. While CCT should be considered if clinically unclear, CXR likely suffices as an initial screening tool. These findings facilitate optimal resource allocation in constrained environments.
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  • 文章类型: Systematic Review
    背景:外伤性肋骨骨折的手术治疗是否能获得更好的结果仍在争论中。在过去的十年中,肋骨骨折的手术稳定性急剧增加。本研究旨在对随机对照试验(RCTs)进行系统评价和荟萃分析,以评估手术治疗与保守治疗成人创伤性多发性肋骨骨折患者的有效性和安全性。
    方法:根据系统评价和荟萃分析指南的首选报告项目进行系统文献综述。我们搜索了MEDLINE,Scopus,和Cochrane中央对照试验登记册,并使用Cochrane偏差风险2工具来评估方法学质量。计算结果的相对风险与95%置信区间(CI):全因死亡率,肺炎发病率,机械通气天数。通过建议分级评估来评估证据的总体确定性,开发和评估(等级)方法,进行试验序贯分析以确定对进一步研究的意义.
    结果:来自719条记录,我们包括了九个RCT,招募了862名患者。患者被分配到手术组(接受胸壁损伤的手术稳定,n=423)或对照组(n=439)。两组的全因死亡率无显著差异(RR=0.53;95%CI0.21~1.38,P=0.35,I2=11%)。然而,在手术组,机械通气时间(平均差异-4.62;95%CI-7.64至-1.60,P<0.00001,I2=94%)和重症监护病房住院时间(平均差异-3.05;95%CI-5.87至-0.22;P<0.00001,I2=96%)均显著缩短,和肺炎发生率(RR=0.57;95%CI0.35~0.92;P=0.02,I2=57%)显著较低。死亡率的试验序贯分析表明,样本量不足以做出明确的判断。GRADE显示此荟萃分析具有非常低的置信度。
    结论:大规模试验的Meta分析显示,与保守治疗相比,多发性肋骨骨折的手术稳定缩短了机械通气的持续时间,降低了肺炎的发生率,但缺乏明显的改善死亡率的证据。试验序贯分析表明需要更多的病例,等级强调了低确定性,强调进一步有针对性的RCT的必要性,尤其是机械通气的病人。
    背景:UMIN临床试验注册UMIN000049365.
    Operative treatment of traumatic rib fractures for better outcomes remains under debate. Surgical stabilization of rib fractures has dramatically increased in the last decade. This study aimed to perform a systematic review and meta-analysis of randomised controlled trials (RCTs) to assess the effectiveness and safety of operative treatment compared to conservative treatment in adult patients with traumatic multiple rib fractures.
    A systematic literature review was performed according to the preferred reporting items for systematic reviews and meta-analyses guidelines. We searched MEDLINE, Scopus, and Cochrane Central Register of Controlled Trials and used the Cochrane Risk-of-Bias 2 tool to evaluate methodological quality. Relative risks with 95% confidence interval (CI) were calculated for outcomes: all-cause mortality, pneumonia incidence, and number of mechanical ventilation days. Overall certainty of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, with trial sequential analysis performed to establish implications for further research.
    From 719 records, we included nine RCTs, which recruited 862 patients. Patients were assigned to the operative group (received surgical stabilization of chest wall injury, n = 423) or control group (n = 439). All-cause mortality was not significantly different (RR = 0.53; 95% CI 0.21 to 1.38, P = 0.35, I2 = 11%) between the two groups. However, in the operative group, duration of mechanical ventilation (mean difference -4.62; 95% CI -7.64 to -1.60, P < 0.00001, I2 = 94%) and length of intensive care unit stay (mean difference -3.05; 95% CI -5.87 to -0.22; P < 0.00001, I2 = 96%) were significantly shorter, and pneumonia incidence (RR = 0.57; 95% CI 0.35 to 0.92; P = 0.02, I2 = 57%) was significantly lower. Trial sequential analysis for mortality indicated insufficient sample size for a definitive judgment. GRADE showed this meta-analysis to have very low to low confidence.
    Meta-analysis of large-scale trials showed that surgical stabilization of multiple rib fractures shortened the duration of mechanical ventilation and reduced the incidence of pneumonia but lacked clear evidence for improvement of mortality compared to conservative treatment. Trial sequential analysis suggested the need for more cases, and GRADE highlighted low certainty, emphasizing the necessity for further targeted RCTs, especially in mechanically ventilated patients.
    UMIN Clinical Trials Registry UMIN000049365.
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  • 文章类型: Journal Article
    钝性胸部损伤的常见机制包括机动车碰撞和跌倒。胸壁损伤包括肋骨骨折和胸骨骨折;治疗包括支持性护理,多模式镇痛,和肺厕所。气胸,血胸,和肺挫伤也很常见,可以预期或根据指示进行导管胸廓造口术。在选择的病例中可以考虑手术治疗。不太常见的损伤模式包括气管支气管树的钝性损伤,食道,隔膜,心,或者主动脉.更经常需要手术干预来解决这些损伤。
    Common mechanisms of blunt thoracic injury include motor vehicle collisions and falls. Chest wall injuries include rib fractures and sternal fractures; treatment involves supportive care, multimodal analgesia, and pulmonary toilet. Pneumothorax, hemothorax, and pulmonary contusions are also common and may be managed expectantly or with tube thoracostomy as indicated. Surgical treatment may be considered in select cases. Less common injury patterns include blunt trauma to the tracheobronchial tree, esophagus, diaphragm, heart, or aorta. Operative intervention is more often required to address these injuries.
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  • 文章类型: Journal Article
    胸部损伤严重威胁着人类健康。最近的研究建议使用计算机断层扫描(CT)观察创伤性气胸(PTX)。然而,需要跨种族验证来克服这种方法在全球应用的潜在障碍。这项研究旨在验证韩国人群中创伤性气胸(PTX)的35毫米规则。
    分析了来自机构注册的数据,复查胸部CT图像。观察失败的因素通过logistic回归分析进行评估,并创建受试者工作曲线以计算最佳截止值。
    总共,286名参与者被纳入本研究。平均PTX尺寸为8.2(3.2-26.5)mm,最初观察到的213例PTX大小≤35mm的患者中有210例(95.3%)成功完成了安全性观察.多变量回归分析显示,>35mm的PTX大小与观察失败有关,并建议截止值为24.5mm。
    大多数CT上创伤PTX≤35mm的患者在没有进行胸廓造口术的情况下进行了成功的4小时观察。此外,>35mm的PTX是观察失败的独立危险因素。考虑到本研究中观察到的较低的最佳临界值和较高的故障率,目前的指导方针需要修改。
    UNASSIGNED: Thoracic injury crucially threatens human health. Recent studies have suggested using computed tomography (CT) to observe traumatic pneumothorax (PTX). However, cross-ethnic validation is required to overcome potential barriers for the global application of this method. This study aimed to validate the 35-mm rule in traumatic PTX in a Korean population.
    UNASSIGNED: Data from the institutional registry were analyzed, and chest CT images were reviewed. Factors for observation failure were evaluated via logistic regression analysis, and a receiver-operating curve was created to calculate the optimal cutoff value.
    UNASSIGNED: In total, 286 participants were included in this study. The average PTX size was 8.2 (3.2-26.5) mm, and 210 of 213 (95.3%) initially observed patients with a PTX size of ≤35 mm successfully completed the safety observation. Multivariate regression analysis revealed that a PTX size of >35 mm is associated with observation failure and suggested a cutoff of 24.5 mm.
    UNASSIGNED: Most patients with traumatic PTX of ≤35 mm on CT had undergone successful 4-h observation without thoracostomy. Additionally, PTX of >35 mm was an independent risk factor for observation failure. Considering the lower optimal cutoff value and high failure rates observed in this study, the current guidelines need modifications.
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  • 文章类型: Journal Article
    目的:本研究旨在确定由心肺复苏术引起的肋骨骨折和其他损伤的发生率,并比较手动和机械辅助心肺复苏术。另一个目的是总结CPR后肋骨骨折手术治疗的文献。
    方法:系统评价和荟萃分析。
    方法:Embase,MedlineOvid,CochraneCentral,WebofScience,谷歌学者。
    方法:检索数据库,以确定报告非创伤性心肺骤停患者胸部按压的CPR相关损伤的研究。进行了亚组分析,以比较手动和机械辅助胸部按压中CPR相关损伤的发生率。本文还对CPR相关肋骨骨折手术的研究报告进行了回顾和总结。
    结果:纳入74项报告CPR相关损伤的研究,共16,629名患者。在60%(95%置信区间[95%CI]49-71)的患者中记录了任何与CPR相关的损伤。肋骨骨折是最常见的损伤,合并患病率为55%(95%CI48-62)。机械辅助心肺复苏术,与手动心肺复苏相比,与心肺复苏相关损伤的风险比1.36相关(95%CI1.17-1.59)。八项研究提供了有关CPR相关肋骨骨折手术稳定的信息。手术的主要指征是在存在多发性肋骨骨折的情况下无法从机械通气中戒断。
    结论:在非创伤性心肺骤停后接受心肺复苏术的患者中经常发生肋骨骨折和其他损伤,尤其是当进行机械CPR时。CPR相关肋骨骨折的手术稳定性仍然相对少见。
    方法:三级,系统评价和荟萃分析。
    OBJECTIVE: This study aims to ascertain the prevalence of rib fractures and other injuries resulting from CPR and to compare manual with mechanically assisted CPR. An additional aim was to summarize the literature on surgical treatment for rib fractures following CPR.
    METHODS: Systematic review and meta-analysis.
    METHODS: Embase, Medline Ovid, Cochrane Central, Web of Science, and Google Scholar.
    METHODS: The databases were searched to identify studies reporting on CPR-related injuries in patients who underwent chest compressions for a non-traumatic cardiopulmonary arrest. Subgroup analysis was conducted to compare the prevalence of CPR-related injuries in manual versus mechanically assisted chest compressions. Studies reporting on surgery for CPR-related rib fractures were also reviewed and summarized.
    RESULTS: Seventy-four studies reporting CPR-related injuries were included encompassing a total of 16,629 patients. Any CPR-related injury was documented in 60% (95% confidence interval [95% CI] 49-71) patients. Rib fractures emerged as the most common injury, with a pooled prevalence of 55% (95% CI 48-62). Mechanically assisted CPR, when compared to manual CPR, was associated with a higher risk ratio for CPR-related injuries of 1.36 (95% CI 1.17-1.59). Eight studies provided information on surgical stabilization of CPR-related rib fractures. The primary indication for surgery was the inability to wean from mechanical ventilation in the presence of multiple rib fractures.
    CONCLUSIONS: Rib fractures and other injuries frequently occur in patients who undergo CPR after a non-traumatic cardiopulmonary arrest, especially when mechanical CPR is administered. Surgical stabilization of CPR-related rib fractures remains relatively uncommon.
    METHODS: Level III, systematic review and meta-analysis.
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  • 文章类型: Journal Article
    目的:目前社会上关于胸主动脉腔内修复术(TEVAR)治疗钝性胸主动脉损伤(BTAI)时机的建议各不相同。先前的研究表明,TEVAR治疗BTAI后,选择性修复与较低的死亡率相关。然而,这些研究缺乏血管外科学会(SVS)主动脉损伤分级和TEVAR相关术后结局等数据.因此,我们使用了血管质量倡议注册,其中包括相关的解剖和结果数据,检查BTAI的紧急/紧急(≤24小时)和选择性TEVAR后的结果。
    方法:纳入了2013年至2022年接受TEVAR治疗BTAI的患者,不包括SVS4级主动脉损伤的患者。我们包括了协变量,如年龄,性别,种族,传输状态,身体质量指数,术前血红蛋白,合并症,药物使用,SVS主动脉损伤分级,共存的伤害,格拉斯哥昏迷量表,和在回归模型中的先前主动脉手术,以计算分配给紧急/紧急或选择性TEVAR的倾向评分。使用反向概率加权逻辑回归和Cox回归评估围手术期结果和5年死亡率。还调整了左锁骨下动脉血运重建/闭塞以及中心和医生的年度容量。
    结果:在1016例患者中,102例(10%)接受了选择性TEVAR。接受选择性修复的患者更有可能进行左锁骨下动脉血运重建(31%vs7.5%;P<.001),并接受术中肝素(94%vs82%;P=.002)。在逆概率加权之后,TEVAR时机与围手术期死亡率之间没有关联(选择性与紧急/紧急:3.9%与6.6%;比值比[OR],1.1;95%置信区间[CI],0.27-4.7;P=.90)和5年死亡率(5.8%vs12%;危险比[HR],0.95;95%CI,0.21-4.3;P>.9)。与紧急/紧急TEVAR相比,选择性修复与术后卒中降低相关(1.0%vs2.1%;调整后的OR[aOR],0.12;95%CI,0.02-0.94;P=0.044),即使在调整术中肝素使用后(aOR,0.12;95%CI,0.02-0.92;P=.042)。选择性TEVAR也与术后立即拔管失败的较低几率相关(39%vs65%;aOR,0.18;95%CI,0.09-0.35;P<.001)和术后肺炎(4.9%vs11%;aOR,0.34;95%CI,0.13-0.91;P=0.031),但任何术后并发症作为复合结局和初次入院期间的再干预的几率相当。
    结论:接受选择性TEVAR的BTAI患者更有可能接受术中肝素治疗。择期和紧急/紧急TEVAR组的围手术期死亡率和5年死亡率相似。术后,选择性TEVAR与较低缺血性卒中相关,肺部并发症,和长期住院。社会指南的未来修改应纳入当前支持将TEVAR用于BTAI的证据。BTAI患者TEVAR的最佳时机及其决定因素应成为未来研究的主题,以促进个性化决策。
    OBJECTIVE: Current societal recommendations regarding the timing of thoracic endovascular aortic repair (TEVAR) for blunt thoracic aortic injury (BTAI) vary. Prior studies have shown that elective repair was associated with lower mortality after TEVAR for BTAI. However, these studies lacked data such as Society for Vascular Surgery (SVS) aortic injury grades and TEVAR-related postoperative outcomes. Therefore, we used the Vascular Quality Initiative registry, which includes relevant anatomic and outcome data, to examine the outcomes following urgent/emergent (≤ 24 hours) vs elective TEVAR for BTAI.
    METHODS: Patients undergoing TEVAR for BTAI between 2013 and 2022 were included, excluding those with SVS grade 4 aortic injuries. We included covariates such as age, sex, race, transfer status, body mass index, preoperative hemoglobin, comorbidities, medication use, SVS aortic injury grade, coexisting injuries, Glasgow Coma Scale, and prior aortic surgery in a regression model to compute propensity scores for assignment to urgent/emergent or elective TEVAR. Perioperative outcomes and 5-year mortality were evaluated using inverse probability-weighted logistic regression and Cox regression, also adjusting for left subclavian artery revascularization/occlusion and annual center and physician volumes.
    RESULTS: Of 1016 patients, 102 (10%) underwent elective TEVAR. Patients who underwent elective repair were more likely to undergo revascularization of the left subclavian artery (31% vs 7.5%; P < .001) and receive intraoperative heparin (94% vs 82%; P = .002). After inverse probability weighting, there was no association between TEVAR timing and perioperative mortality (elective vs urgent/emergent: 3.9% vs 6.6%; odds ratio [OR], 1.1; 95% confidence interval [CI], 0.27-4.7; P = .90) and 5-year mortality (5.8% vs 12%; hazard ratio [HR], 0.95; 95% CI, 0.21-4.3; P > .9).Compared with urgent/emergent TEVAR, elective repair was associated with lower postoperative stroke (1.0% vs 2.1%; adjusted OR [aOR], 0.12; 95% CI, 0.02-0.94; P = .044), even after adjusting for intraoperative heparin use (aOR, 0.12; 95% CI, 0.02-0.92; P = .042). Elective TEVAR was also associated with lower odds of failure of extubation immediately after surgery (39% vs 65%; aOR, 0.18; 95% CI, 0.09-0.35; P < .001) and postoperative pneumonia (4.9% vs 11%; aOR, 0.34; 95% CI, 0.13-0.91; P = .031), but comparable odds of any postoperative complication as a composite outcome and reintervention during index admission.
    CONCLUSIONS: Patients with BTAI who underwent elective TEVAR were more likely to receive intraoperative heparin. Perioperative mortality and 5-year mortality rates were similar between the elective and emergent/urgent TEVAR groups. Postoperatively, elective TEVAR was associated with lower ischemic stroke, pulmonary complications, and prolonged hospitalization. Future modifications in society guidelines should incorporate the current evidence supporting the use of elective TEVAR for BTAI. The optimal timing of TEVAR in patients with BTAI and the factors determining it should be the subject of future study to facilitate personalized decision-making.
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  • 文章类型: Journal Article
    胸部创伤的发病率在全球范围内呈上升趋势,它需要注意,因为它是发病率和死亡率的主要原因。全球,胸部创伤是第二大常见的死亡原因,也是导致残疾和住院的主要原因。我们的主要目标是系统地审查患病率,模式,原因,manner,发病率,中东成年人胸部创伤的死亡率。此范围审查是根据系统审查和荟萃分析(PRISMA)指南的首选报告项目进行的。通过使用数据库对相关文章进行筛选,包括PubMed,Scopus,和WebofScience。搜索数据库和审查参考文献列表共发现128篇文章。最后,九篇文章符合纳入标准。大多数受害者是男性,正如本系统综述中所有研究报告的那样。胸部创伤最常见的原因是道路交通事故(RTA),正如九项纳入研究中的七项所述。胸部创伤的模式包括气胸,血胸,血气胸,肺挫伤,连击胸,肋骨骨折,和膈肌损伤。在研究中,胸部创伤后的死亡率和发病率各不相同。然而,大多数研究显示,发病率高于死亡率。胸部创伤带来经济和社会负担,这是一个严重的问题,尤其是在第二个到第三个十年的男性中。应考虑采取预防措施,以减少胸部创伤及其相关并发症的发生率。
    Chest trauma incidence is increasing worldwide, and it requires attention as it is a major cause of morbidity and mortality. Worldwide, chest trauma is the second most common cause of mortality and a major cause of disability and hospitalization. Our main aim is to systematically review the prevalence, pattern, causes, manner, morbidity, and mortality of chest trauma in the Middle East among adults. This scoping review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Screening of the relevant articles was done by using databases, including PubMed, Scopus, and Web of Science. A total of 128 articles were found as a result of searching the databases and reviewing the reference lists. Finally, nine articles met the inclusion criteria. Most of the victims were males, as reported by all studies in this systemic review. The most common cause of chest trauma was road traffic accident (RTA), as described in seven out of the nine included studies. The pattern of chest trauma included pneumothorax, hemothorax, hemopneumothorax, lung contusion, flail chest, rib fracture, and diaphragmatic injury. The rate of mortality and morbidity following chest trauma varied among the studies. However, most of the studies revealed higher rates of morbidity than mortality. Chest trauma carries economic and social burdens, and it is a serious issue, especially in males in the second to third decades. Preventive measures should be considered to decrease the prevalence of chest trauma and its related complications.
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  • 文章类型: Editorial
    暂无摘要。
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  • 文章类型: Journal Article
    背景:战斗场景中的主要威胁是带有弹道保护板(BPP)的非穿透性弹道冲击的“装甲钝器创伤”(BABT)。这种影响导致压力波通过组织传播,可能造成危及生命的损害。迄今为止,没有标准化的程序来快速虚拟测试BPP设计的有效性。这项研究的目的是开发一部小说,解剖学上准确,有限元建模框架,作为评估和评价BPP在保护躯干免受战场获得的非穿透性冲击的生物力学功效的决策工具。
    方法:要用BPP模拟钝器撞击,两种类型的BPP代表威胁级别III和IV板的通用设计,和一个通用的5.56毫米子弹被建模,根据它们的真实尺寸,物理和机械特性(III级钢板较小,更薄,比IV级板轻)。通过体模测试对模型进行了验证。
    结果:IV级钢板在弹道冲击后在表面组织中引起更大的应变和应力,由于它更大,比III级板更厚,更重;在非穿透冲击的情况下,传递到BPP后面的表面组织的冲击波更大。例如-在板IV级的情况下,皮肤和脂肪组织的应变和应力的体积组织暴露直方图下的面积分别为16.6-19.2%和17.3-20.3%。对于应变和应力,分别。验证表明物理体模实验和模拟之间有很强的一致性,它们之间只有6.37%的差异。
    结论:我们的建模提供了一种通用的,在原型设计阶段,为BPP的行业和客户提供强大的测试框架,或在采购决策和投标中对候选产品进行定量标准化评估。
    BACKGROUND: A major threat in combat scenarios is the \'behind armor blunt trauma\' (BABT) of a non-penetrating ballistic impact with a ballistic protective plate (BPP). This impact results in pressure waves that propagate through tissues, potentially causing life-threatening damage. To date, there is no standardized procedure for rapid virtual testing of the effectiveness of BPP designs. The objective of this study was to develop a novel, anatomically-accurate, finite element modeling framework, as a decision-making tool to evaluate and rate the biomechanical efficacy of BPPs in protecting the torso from battlefield-acquired non-penetrating impacts.
    METHODS: To simulate a blunt impact with a BPP, two types of BPPs representing generic designs of threat-level III and IV plates, and a generic 5.56 mm bullet were modeled, based on their real dimensions, physical and mechanical characteristics (plate level-III is smaller, thinner, and lighter than plate level-IV). The model was validated by phantom testing.
    RESULTS: Plate level-IV induced greater strains and stresses in the superficial tissues post the ballistic impact, due to the fact that it is larger, thicker and heavier than plate level-III; the shock wave which is transferred to the superficial tissues behind the BPP is greater in the case of a non-penetrating impact. For example - the area under volumetric tissue exposure histograms of strains and stresses for the skin and adipose tissues were 16.6-19.2% and 17.3-20.3% greater in the case of plate level-IV, for strains and stresses, respectively. The validation demonstrates a strong agreement between the physical phantom experiment and the simulation, with only a 6.37% difference between them.
    CONCLUSIONS: Our modelling provides a versatile, powerful testing framework for both industry and clients of BPPs at the prototype design phase, or for quantitative standardized evaluations of candidate products in purchasing decisions and bids.
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  • 文章类型: Journal Article
    肋骨骨折是胸部创伤的常见后遗症,并与显著的发病率相关。由于易于使用和并发症发生率最低,已提出将竖脊神经阻滞(ESB)作为肋骨骨折的替代一线区域技术。我们旨在调查围绕这一主题的当前文献,重点是疼痛和呼吸结局。
    在Medline上进行了全面的文献检索,Embase,WebofScience,Scopus,和Cochrane数据库。使用“竖脊肌块”和“肋骨骨折”的关键词来形成搜索策略。包括以英文发表的研究ESB作为急性肋骨骨折的镇痛干预措施的论文。排除标准为手术肋骨固定术,或ESB的适应症不是肋骨骨折。
    有37项研究符合本次范围审查的纳入标准。其中,31项研究报告了疼痛结果,并证明在第一个24小时内给药后疼痛评分降低了40%。在8项研究中报告了呼吸参数,其中证明了诱因肺活量测定的增加。呼吸系统并发症未得到一致报告。ESB与最小的并发症相关;仅报告了5例血肿和感染(发生率0.6%),这些都不需要进一步干预。
    目前有关ESB在肋骨骨折治疗中的文献对疗效和安全性进行了积极的定性评估。疼痛和呼吸参数的改善几乎是普遍的。这项审查的显著结果是ESB的安全性得到了改善。即使在抗凝和凝血病的情况下,ESB也与需要干预的并发症无关。仍然缺乏大量的队列,前瞻性数据。此外,与现有技术相比,目前的研究没有反映出呼吸系统并发症发生率的改善.一起来看,这些领域应该是任何未来研究的重点。
    UNASSIGNED: Rib fractures are a common sequelae of chest trauma and are associated with significant morbidity. The erector spinae nerve block (ESB) has been proposed as an alternative first-line regional technique for rib fractures due to ease of administration and minimal complication profile. We aimed to investigate the current literature surrounding this topic with a focus on pain and respiratory outcomes.
    UNASSIGNED: A comprehensive literature search was performed on the Medline, Embase, Web of Science, Scopus, and Cochrane databases. Keywords of \"erector spinae block\" and \"rib fractures\" were used to form the search strategy. Papers published in English investigating ESB as an analgesic intervention for acute rib fracture were included. Exclusion criteria were operative rib fixation, or where the indication for ESB was not rib fracture.
    UNASSIGNED: There were 37 studies which met the inclusion criteria for this scoping review. Of these, 31 studies reported on pain outcomes and demonstrated a 40% decrease in pain scores post administration within the first 24 hours. Respiratory parameters were reported in 8 studies where an increase in incentive spirometry was demonstrated. Respiratory complication was not consistently reported. ESB was associated with minimal complications; only 5 cases of haematoma and infection were (incidence 0.6%) reported, none of which required further intervention.
    UNASSIGNED: Current literature surrounding ESB in rib fracture management provides a positive qualitative evaluation of efficacy and safety. Improvements in pain and respiratory parameters were almost universal. The notable outcome from this review was the improved safety profile of ESB. The ESB was not associated with complications requiring intervention even in the setting of anticoagulation and coagulopathy. There still remains a paucity of large cohort, prospective data. Moreover, no current studies reflect an improvement in respiratory complication rates compared to current techniques. Taken together, these areas should be the focus of any future research.
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