Targeted medication review

  • 文章类型: Observational Study
    背景:钠葡萄糖协同转运蛋白-2(SGLT-2)抑制剂和胰高血糖素样肽1受体(GLP-1)激动剂被推荐用于患有2型糖尿病(T2D)和动脉粥样硬化性心血管疾病(ASCVD)或心力衰竭(HF)的患者,以降低心血管相关死亡率。这项研究的目的是评估远程健康靶向药物审查(TMR)计划,以确定患者是否接受这些循证药物。
    方法:这是一项针对Medicare注册的TMR计划的观察性描述性研究,药物治疗管理-符合一项保险计划的患者。处方声明和患者访谈确定了将受益于SGLT-2抑制剂或GLP-1激动剂的个体。将传真发送给患者提供者,并提供有关目标药物的教育信息。描述性统计数据描述了120天后处方靶向药物的患者的特征和比例。双变量统计检验评估了年龄之间的关联,性别,药物的数量,供应商数量,和贫困水平,采用有针对性的药物。
    结果:在与患者交谈后,共有1127人中的1106人收到了传真给其提供者。在有提供者传真的患者中,69(6%)名患者在120天后按处方配药。开始靶向药物治疗的个体(67±10岁)与未进行靶向药物治疗的患者(71±10岁)之间的年龄存在显着差异(p=0.001)。
    结论:一项TMR能有效地识别出T2D和ASCVD或HF患者,并能从循证药物治疗中获益。虽然年轻患者更有可能接受这些药物治疗,干预后4个月内这些药物的总体摄入量低于预期.
    Sodium glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide 1 receptor (GLP-1) agonists are recommended for patients with type two diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD) or heart failure (HF) to reduce cardiovascular-related mortality. The objective of this study was to evaluate a telehealth targeted medication review (TMR) program to identify patients for uptake of these evidence-based medications.
    This was an observational descriptive study of a TMR program for Medicare-enrolled, Medication Therapy Management-eligible patients in one insurance plan. Prescription claims and patient interviews identified individuals who would benefit from SGLT-2 inhibitors or GLP-1 agonists. Facsimiles were sent to providers of patients with educational information about the targeted medications. Descriptive statistics described characteristics and proportion of patients prescribed targeted medications after 120 days. Bivariate statistical tests evaluated associations between age, sex, number of medications, number of providers, and poverty level with adoption of targeted medications.
    A total of 1106 of 1127 had a facsimile sent to their provider after a conversation with the patient. Among patients with a provider facsimile, 69 (6%) patients filled a prescription for a targeted medication after 120 days. There was a significant difference in age between individuals who started a targeted medication (67 ± 10 years) compared with patients who did not (71 ± 10 years) (p = 0.001).
    A TMR efficiently identified patients with T2D and ASCVD or HF who would benefit from evidence-based medications. Although younger patients were more likely to receive these medications, the overall uptake of these medications within four months of the intervention was lower than expected.
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  • 文章类型: Journal Article
    UNASSIGNED:MedicareD部分药物治疗管理(MTM)计划对药物和卫生服务利用具有积极影响。然而,对它的使用知之甚少,更不用说在种族和少数民族中的使用了。
    UNASSIGNED:检查老年医疗保险受益人的MTM服务使用情况,并确定任何种族和族裔差异模式。
    未经评估:对2017年医疗保险管理数据的回顾性横断面分析,链接到区域运行状况资源文件。与MTM服务性质有关的14项成果,initiation,数量,和交付使用后勤检查,负二项式,和Cox比例风险回归模型。
    UNASSIGNED:发现种族和种族差异在结果之间具有不同的模式。例如,与白人患者相比,黑人患者选择退出MTM的几率高出8%(比值比[OR]=1.08,95%置信区间[CI]=1.03-1.14),西班牙裔患者高57%(OR=1.57,95%CI=1.42-1.72),亚洲患者高于57%(OR=1.57,95%CI=1.33-1.85)。过去几年中,Black患者继续进行MTM的几率降低了12%(OR=0.88,95%CI=0.86-0.90),其他患者降低了3%(OR=0.97,95%CI=0.95-0.99)。此外,西班牙裔患者在接受MTM后接受全面药物审查(CMR)的可能性降低了9%(风险比[HR]=0.91,95%CI=0.85-0.97),亚洲患者低9%(HR=0.91,95%CI=0.87-0.94),其他患者低3%(HR=0.97,95%CI=0.95-0.99)。西班牙裔和亚裔患者更有可能让其他人接受CMR。
    UNASSIGNED:确定了MTM服务利用中的种族和种族差异。尽管特定利用结果的差异因种族/族裔而异,显然,这些差异存在,可能导致脆弱社区无法充分受益于MTM服务。应探索差异的原因,以指导未来MedicareD部分MTM计划的改革。
    UNASSIGNED: The Medicare Part D medication therapy management (MTM) program has positive effects on medication and health service utilization. However, little is known about its utilization, much less so about the use among racial and ethnic minorities.
    UNASSIGNED: To examine MTM service utilization among older Medicare beneficiaries and to identify any racial and ethnic disparity patterns.
    UNASSIGNED: A retrospective cross-sectional analysis of 2017 Medicare administrative data, linked to the Area Health Resources Files. Fourteen outcomes related to MTM service nature, initiation, quantity, and delivery were examined using logistic, negative binomial, and Cox proportional hazards regression models.
    UNASSIGNED: Racial and ethnic disparities were found with varying patterns across outcomes. For example, compared with White patients, the odds of opting out of MTM were 8% higher for Black patients (odds ratio [OR] = 1.08, 95% confidence interval [CI] = 1.03-1.14), 57% higher for Hispanic patients (OR = 1.57, 95% CI = 1.42-1.72), and 57% higher for Asian patients (OR = 1.57, 95% CI = 1.33-1.85). The odds of continuing MTM from the previous years were 12% lower for Black patients (OR = 0.88, 95% CI = 0.86-0.90) and 3% lower for other patients (OR = 0.97, 95% CI = 0.95-0.99). In addition, the probability of being offered a comprehensive medication review (CMR) after MTM enrollment was 9% lower for Hispanic patients (hazard ratio [HR] = 0.91, 95% CI = 0.85-0.97), 9% lower for Asian patients (HR = 0.91, 95% CI = 0.87-0.94), and 3% lower for other patients (HR = 0.97, 95% CI = 0.95-0.99). Hispanic and Asian patients were more likely to have someone other than themselves receive a CMR.
    UNASSIGNED: Racial and ethnic disparities in MTM service utilization were identified. Although the disparities in specific utilization outcomes vary across racial/ethnic groups, it is evident that these disparities exist and may result in vulnerable communities not fully benefiting from the MTM services. Causes of the disparities should be explored to inform future reform of the Medicare Part D MTM program.
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  • 文章类型: Journal Article
    Background:Finding ways to reduce prescribing of potentially inappropriate medications (PIMs) among patients with dementia is necessary.
    To evaluate an automated targeted medication review (TMR) service to reduce PIM prescribing among patients with dementia.
    This was a retrospective observational analysis of patients in a Medication Therapy Management (MTM) program for year 2017. Patients included if Medicare enrolled, MTM eligible, had dementia, and with PIM prescribing. Descriptive statistics described reduced PIM prescribing. Odds ratios (ORs) assessed prescriber relationship with PIM prescribing. Regression evaluated relationship between patient characteristics and discontinued PIMs.
    A total of 33 696 TMRs were triggered for 17 933 patients. Four months later, 11 608 TMRs led to a discontinued PIM among 8002 patients. Medications with the largest discontinuations were antihistamines (56%), muscle relaxants (53%), antiemetics (53%), and typical antipsychotics (40%). Physician primary care providers (PCPs) were more likely than nonphysician PCPs (OR = 4.54; 95% CI = 4.15-4.97; P < 0.001), psychiatrists (OR = 1.64; 95%CI = 1.44-1.86; P < 0.001), and neurologists (OR = 4.48; 95% CI = 4.07-4.93; P < 0.001) to prescribe medications to treat dementia and PIMs. Regression showed that younger age, female gender, higher poverty level, and a greater number of pharmacies, medications, and prescribers were associated with discontinued PIMs. Conclusions and Relevance: TMRs were effective in reducing PIM prescribing. Younger patients, individuals living in higher poverty levels, and patients with multiple prescribers or pharmacies may benefit most from this service. TMRs in primary care offices may reduce PIM prescribing.
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  • 文章类型: Journal Article
    It has been one year--since January 1, 2013--that comprehensive medication review has been recognized as a medication therapy management (MTM) service that must be offered annually by Medicare Part D prescription drug plans to \"qualified beneficiaries.\" This requirement solidifies the Centers for Medicare & Medicaid Services\' commitment to ensure all beneficiaries, including those in long-term care facilities, receive quality MTM services. Consultant pharmacists, who have long provided federally mandated medication regimen review services, may have their first opportunity to be paid for the additional services that they provide to individual Medicare beneficiaries residing in those facilities.
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