背景:许多研究已经证明了食用奇亚籽对代谢因素的积极影响。然而,临床试验结果不一致.
目的:本研究的目的是对现有的随机对照试验进行系统评价和荟萃分析,以探讨奇亚籽食用对体重(BW)的影响。身体成分,血压,和血糖控制。
方法:对Scopus进行了全面搜索,PubMed,Medline通过Ovid,ISIWebofScience,和截至2023年8月的学者谷歌数据库。
方法:感兴趣的结果包括收缩压(SBP),舒张压(DBP),BW,体重指数(BMI),身体脂肪百分比,腰围(WC),空腹血糖(FBG),和血红蛋白A1c(HbA1c)。
方法:使用加权平均差(WMD)和95%CI来确定效应大小。
结果:共8项符合条件的研究纳入分析。研究结果表明,SBP(WMD:-7.19mmHg;95%CI,-10.63至-3.73;P<.001)和DBP(WMD:-6.04mmHg,95%CI,-9.58至-2.49;P=.001)。然而,对BW没有观察到显著影响,身体脂肪百分比,WC,BMI,FBG,和HbA1c。亚组分析表明,在基线SBP小于140mmHg的参与者中,chia种子对SBP的影响是显着的,但效果不依赖于给药剂量。
结论:Chia种子消费对SBP和DBP有积极影响,但对BW没有显著影响,身体成分,或血糖参数。然而,在解释这些发现时,纳入研究的数据量有限应被视为一种局限性.
背景:PROSPERO注册号。CRD42023462575。
BACKGROUND: Numerous studies have demonstrated the positive effects on metabolic factors of consuming chia seeds. However, the results of clinical trials have been inconsistent.
OBJECTIVE: The aim of this study was to conduct a systematic review and meta-analysis of available randomized controlled trials to explore the effects of chia seed consumption on body weight (BW), body composition, blood pressure, and glycemic control.
METHODS: A comprehensive search was conducted on the Scopus, PubMed, Medline via Ovid, ISI Web of Science, and Scholar Google databases up to August 2023.
METHODS: The outcomes of interest included systolic blood pressure (SBP), diastolic blood pressure (DBP), BW, body mass index (BMI), body fat percentage, waist circumference (WC), fasting blood glucose (FBG), and hemoglobin A1c (HbA1c).
METHODS: Weighted mean difference (WMD) and 95% CIs were used to determine the effect size.
RESULTS: A total of 8 eligible studies were included in the analysis. The findings revealed a significant reduction in SBP (WMD: -7.19 mmHg; 95% CI, -10.63 to -3.73; P < .001) and DBP (WMD: -6.04 mmHg, 95% CI, -9.58 to -2.49; P = .001). However, no significant effects were observed on BW, body fat percentage, WC, BMI, FBG, and HbA1c. Subgroup analysis indicated that the effect of chia seed on SBP was significant in participants with a baseline SBP of less than 140 mmHg, but the effect was not dependent on the administered dose.
CONCLUSIONS: Chia seed consumption has positive effects on SBP and DBP but does not significantly impact BW, body composition, or glycemic parameters. However, the limited amount of data from included studies should be considered as a limitation while interpreting these findings.
BACKGROUND: PROSPERO registration no. CRD42023462575.