Surgical disparities

  • 文章类型: Journal Article
    背景:结直肠癌(CRC)是美国农村地区的主要死亡原因。农村人口众多且异质,然而,与患者相关的CRC获取不公平的驱动因素仍未得到充分研究.这项研究旨在确定接受择期CRC手术几率较低的脆弱农村人群。
    方法:对政策地图和美国人口普查局的评估确定了人口最多的州(按农村总人口计算)与手术入路不良相关的因素。为了评估这些确定的因素是否与选择性CRC手术的可及性减少相关,使用2007年至2020年全国住院患者样本评估了69,212例接受CRC手术的农村患者的住院情况.农村被定义为人口<250,000的县。多变量逻辑回归模型评估择期CRC手术的预测因素。患者和医院层面的因素相互作用是先验指定的。
    结果:超过72%的农村住院患者是择期住院。多元回归分析表明,年龄较大,多浊度,黑人种族,拉丁裔西班牙裔,医疗补助保险,农村医院预测择期CRC手术的几率较低。关于互动分析,相对于农村,高危患者在城市机构接受择期CRC手术的可能性较小.
    结论:在这项针对农村居民的大型研究中,少数民族,长者,医疗补助受益人接受选择性CRC手术的机会大大减少,特别是在城市环境中接受护理时。未来的研究应该集中在探索这些农村人口健康的可操作的社会驱动因素。研究结果强调,需要采取多层次干预措施,以增加农村地区获得公平和优质的癌症外科护理的机会。
    BACKGROUND: Colorectal cancer (CRC) is a leading cause of death in rural America. Rural populations are large and heterogeneous, yet patient-related drivers of inequities in CRC access are understudied. This study aimed to identify vulnerable rural populations at lower odds of undergoing elective CRC surgery.
    METHODS: Evaluation of the Policy Map and United States Census Bureau identified factors associated with poor surgical access in the most populous states (by total rural population). To assess whether these identified factors were associated with reduced access to elective CRC surgery, the 2007 to 2020 National Inpatient Sample was used to evaluate 69,212 hospitalizations of rural patients undergoing CRC surgery. Rural was defined as counties with a population of <250,000. Multivariable logistic regression models assessed predictors of elective CRC surgery. Patient- and hospital-level factor interactions were specified a priori.
    RESULTS: More than 72% of hospitalizations of rural patients were elective. Multivariate regression analysis demonstrated that older age, multimorbidity, Black race, Latino-Hispanic ethnicity, Medicaid insurance, and rural hospitals predicted lower odds of elective CRC surgery. On interaction analyses, high-risk patients were less likely to undergo elective CRC surgery in urban facilities relative to rural.
    CONCLUSIONS: In this large study of rural dwellers, ethnoracial minorities, elders, and Medicaid beneficiaries had profoundly less access to elective CRC surgery, especially when care was received in urban settings. Future studies should focus on exploring actionable social drivers of health in these rural populations. Findings underscore the need for multilevel interventions to enhance rural access to equitable and quality surgical cancer care.
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  • 文章类型: Journal Article
    背景:肋骨骨折(SSRF)的手术稳定与较低的死亡率和较少的并发症相关。这项研究评估了接受SSRF的决定是否与年龄有关,种族,种族,和保险状况,并评估相关的临床结果。
    方法:这项回顾性分析包括2016年至2020年在创伤质量改善计划中接受SSRF的年龄≥45岁的肋骨骨折患者。种族,种族,并收集了保险状态。将年龄分为两组:45-64和65。结果包括呼吸机相关性肺炎,计划外气管插管,急性呼吸窘迫综合征,住院死亡率,严重并发症后未能抢救(FTR),和呼吸系统并发症后的FTR。Logistic回归模型适合评估结果,控制性别,身体质量指数,伤害严重程度评分,连击胸,慢性阻塞性肺疾病,充血性心力衰竭,和吸烟。
    结果:两千八百三十九名年龄在45-64岁的患者和1828名年龄在65岁以上的患者接受了SSRF。这些组之间的临床结果没有显着差异。分析显示SSRF与呼吸机相关性肺炎,计划外插管,急性呼吸窘迫综合征,住院死亡率,严重并发症后的FTR,呼吸系统并发症后或FTR不因年龄而异(P>0.05)。黑色(比值比[OR]0.67;95%置信区间[CI]:0.59-0.77;P<0.001),西班牙裔(OR0.80;95%CI:0.71-0.91;P<0.001),和医疗补助(OR=0.85;95%CI=0.76-0.95;P=0.005)患者接受SSRF的可能性较小。
    结论:在接受SSRF的45-64岁和≥65岁的成年人之间,临床结果没有差异。年龄较大不应排除患者接受SSRF。需要进一步的工作来改善布莱克的利用率不足,西班牙裔和医疗补助患者。
    BACKGROUND: Surgical stabilization of rib fractures (SSRF) is associated with lower rates of mortality and fewer complications. This study evaluates whether the decision to undergo SSRF is associated with age, race, ethnicity, and insurance status and assesses associated clinical outcomes.
    METHODS: This retrospective analysis included patients ≥45 y old with rib fractures who underwent SSRF in the Trauma Quality Improvement Program from 2016 to 2020. Race, ethnicity, and insurance statuses were collected. Age in years was dichotomized into two groups: 45-64 and 65+. Outcomes included ventilator-associated pneumonia, unplanned endotracheal intubation, acute respiratory distress syndrome, in-hospital mortality, failure to rescue (FTR) after major complications, and FTR after respiratory complications. Logistic regression models were fit to evaluate outcomes, controlling for gender, body mass index, Injury Severity Score, flail chest, chronic obstructive pulmonary disease, congestive heart failure, and smoking.
    RESULTS: Two thousand eight hundred thirty-nine patients aged 45-64 and 1828 patients aged 65+ underwent SSRF. No significant difference in clinical outcomes was noted between these groups. Analysis showed that the association of SSRF with ventilator-associated pneumonia, unplanned intubation, acute respiratory distress syndrome, in-hospital mortality, FTR after a major complication, or FTR after a respiratory complication did not vary by age (P > 0.05). Black (odds ratio [OR] 0.67; 95% confidence interval [CI]: 0.59-0.77; P < 0.001), Hispanic (OR 0.80; 95% CI: 0.71-0.91; P < 0.001), and Medicaid (OR = 0.85; 95% CI = 0.76-0.95; P = 0.005) patients were less likely to receive SSRF.
    CONCLUSIONS: No differences in clinical outcomes were measured between adults aged 45-64 and ≥65 who underwent SSRF. Older age should not preclude patients from receiving SSRF. Further work is needed to improve underutilization in Black, Hispanic and Medicaid patients.
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  • 文章类型: Journal Article
    背景:成像指南建议采用超声(US)优先评估阑尾炎的方法,以最大程度地减少辐射。然而,US与计算机断层扫描(CT)利用率之间的关联尚不清楚.我们旨在确定US利用率的增加与小儿急性阑尾炎的CT评估率之间的相关性。
    方法:我们使用2019年全国急诊科样本进行了一项回顾性队列研究。符合条件的患者年龄小于18岁,诊断为阑尾炎。成像由当前程序术语代码确定。同时成像被定义为在同一遭遇期间使用US和CT。我们计算了并发成像的住院率,并将医院分为三位数:低(<20%),中等(20%-40%),高(>40%)。我们开发了具有逆概率加权的广义序数逻辑回归模型,以评估并发成像关联的患者特征和住院率。
    结果:我们的分析包括485家医院和23,976名患者。34%的人在最低的医院接受治疗,35%在中间,最高的三等医院占31%。我们观察到增加US使用和同时使用成像之间存在负相关(-0.27,P<0.001)。与白人相比,黑人(调整比值比[aOR][95%置信区间{CI}]:0.6,[0.4-0.9])和西班牙裔(aOR[95%CI]:0.7[0.5-0.9])出现在高并发成像率医院的几率显着降低。与最高收入四分位数(aOR[95%CI]:1.9[1.2-3.2])和最低收入四分位数(aOR[95%CI]:3.7[1.1-13.1])的患者相比,出现在较高并发成像率医院的几率更高。
    结论:在诊断阑尾炎时,美国使用的增加与CT使用的减少相关。白人儿童和社会经济较低社区的儿童更有可能去高并发成像使用的医院。
    BACKGROUND: Imaging guidelines recommend an ultrasound (US)-first approach to evaluate appendicitis to minimize radiation. However, the association between US and computed tomography (CT) utilization remains unclear. We aimed to determine how increased US utilization correlated with the rate of CT evaluation of pediatric acute appendicitis.
    METHODS: We conducted a retrospective cohort study using the 2019 Nationwide Emergency Department Sample. Eligible patients were aged less than 18 y with a diagnosis of appendicitis. Imaging was determined by Current Procedural Terminology codes. Concurrent imaging was defined as US and CT use during the same encounter. We calculated the hospital rate of concurrent imaging and categorized hospitals into tertiles: low (< 20%), medium (20%-40%), and high (> 40%). We developed generalized ordinal logistic regression models with inverse probability weighting to assess patient characteristics and hospital rates of concurrent imaging associations.
    RESULTS: Our analysis included 485 hospitals and 23,976 patients. Thirty four percent were treated at hospitals in the lowest, 35% at the middle, and 31% at the highest tertile hospitals. We observed a negative correlation (-0.27, P < 0.001) between increasing US use and concurrent imaging use. The odds of presenting to a higher concurrent imaging rate hospital were significantly lower for Blacks (adjusted odds ratio [aOR] [95% confidence interval {CI}]: 0.6, [0.4-0.9]) and Hispanics (aOR [95% CI]: 0.7 [0.5-0.9]) in comparison to Whites. The odds of presenting to a higher concurrent imaging rate hospital were higher for patients in the second (aOR [95% CI]: 1.9 [1.2-3.2]) and lowest income quartile (aOR [95% CI]: 3.7 [1.1-13.1]) compared to the highest income quartile.
    CONCLUSIONS: Increased US use correlated with decreased CT utilization for diagnosing appendicitis. White children and those in lower socioeconomic neighborhoods are more likely to visit hospitals with high concurrent imaging use.
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  • 文章类型: Journal Article
    目标:2024年胃肠道外科峰会将消化道外科学会(SSAT)召集在一起,外科肿瘤学会(SSO),和大学外科医生协会(SUS)成员评估胃肠道(GI)手术的当前状态。本报告回顾了专门全体会议之后的主要讨论和建议,这些讨论和建议解决了提供高质量,所有患者的胃肠道手术。
    方法:峰会于1月14日至16日举行。在全体会议上,“确定专业外科医生在确保高质量方面的作用和影响,可接近的腹部手术,\"领导人,SSAT的崛起领导人和成员,SSO和SUS遇到并讨论了提供高质量、可访问的胃肠道手术。
    结果:可操作的建议,以应对提供高质量,进行了可访问的胃肠道手术护理,包括参与社区和患者,在医院和外科医生之间建立联盟,并建立胃肠外科护理标准。
    结论:外科医生,医院系统和外科学会可以改善所有胃肠道手术患者的医疗保健机会和结果。
    BACKGROUND: The 2024 GI Surgery Summit brought together Society for Surgery of the Alimentary Tract (SSAT), Society of Surgical Oncology (SSO), and Society of University Surgeons (SUS) members to assess the current state of gastrointestinal (GI) surgery. This report reviews the key discussions and recommendations after the dedicated plenary session that addressed challenges in providing high-quality, accessible GI surgery for all patients.
    METHODS: The Summit took place from January 14 to 16. During the plenary session \"Defining the role and impact of specialty surgeons in ensuring high-quality, accessible abdominal surgery,\" leaders, rising leaders, and members of SSAT, SSO, and SUS met and discussed challenges in providing high-quality, accessible GI surgery.
    RESULTS: Actionable recommendations to address the challenges in providing high-quality, accessible GI surgical care were made, including engaging communities and patients, building alliances across hospitals and surgeons, and establishing standards of GI surgical care.
    CONCLUSIONS: Surgeons, hospital systems, and surgical societies can improve healthcare access and outcomes for all GI surgical patients.
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  • 文章类型: Journal Article
    背景:健康的社会生态决定因素(SEDOHs)影响手术结局的差异。然而,SEDOHs很难测量,限制了我们解决差距的能力。使用经过验证的调查(SEDOH-88),我们评估了阿拉巴马州三个农村社区的SEDOHs.我们假设SEDOHs在各个站点之间会有很大差异,但是测量它们是可以接受和可行的。
    方法:这是一项前瞻性维护的数据库的回顾性回顾,该数据库涉及完成SEDOH-88的手术患者,以及2021年8月至2023年7月评估其可接受性或可行性的二级调查。包括接受内窥镜检查的患者,微创,或在三家乡村医院进行开放手术:Demopolis(DM),亚历山大市(AC),格林维尔(GV)。
    结果:107名参与者包括来自DM的48名(44.9%),27(25.2%)来自AC,以及来自GV的32名(29.9%),分别。中位年龄为64岁,65.6%为女性。当通过个别因素比较DM与AC和GV时,DM的黑人人口最多(78.7对22.2对48.3%,P<0.001),并且更经常需要帮助阅读医院材料(20.5对3.7对10.3%,P=0.007)。当通过结构和环境因素比较DM与AC和GV时,DM的医疗补助参保人数更多(27.3对3.7对6.9%,P=0.033),缺乏新鲜农产品(18.2对25.9对39.3%,P=0.033)和互联网接入(63.6对100.0对86.2%,P<0.001)。SEDOH-88的总体可接受性和可行性评分为90.9%。
    结论:农村社区在个人(种族或健康素养)方面存在显着差异,结构(保险),和环境因素(营养食品或互联网接入)。SEDOH-88的高度可接受性和可行性表明它在确定未来减少差距干预措施的目标方面具有潜在的实用性。
    BACKGROUND: Socioecological determinants of health (SEDOHs) influence disparities in surgical outcomes. However, SEDOHs are challenging to measure, limiting our ability to address disparities. Using a validated survey (SEDOH-88), we assessed SEDOHs in three rural communities in Alabama. We hypothesized that SEDOHs would vary significantly across sites but measuring them would be acceptable and feasible.
    METHODS: This was a retrospective review of a prospectively maintained database involving surgical patients who completed the SEDOH-88 and a secondary survey assessing it\'s acceptability or feasibility from August 2021 to July 2023. Included patients underwent endoscopic, minimally invasive, or open surgery at three rural hospitals: Demopolis (DM), Alexander City (AC), and Greenville (GV).
    RESULTS: The 107 participants comprised 48 (44.9%) from DM, 27 (25.2%) from AC, and 32 (29.9%) from GV, respectively. The median age was 64 y, and 65.6% were female. When comparing DM to AC and GV by individual factors, DM had the largest Black population (78.7 versus 22.2 versus 48.3%, P < 0.001) and more often required help reading hospital materials (20.5 versus 3.7 versus 10.3%, P = 0.007). When comparing DM to AC and GV by structural and environmental factors, DM had more Medicaid enrollees (27.3 versus 3.7 versus 6.9%, P = 0.033) and lacked fresh produce (18.2 versus 25.9 versus 39.3%, P = 0.033) and internet access (63.6 versus 100.0 versus 86.2%, P < 0.001). The SEDOH-88 had an overall 90.9% positive acceptability and feasibility score.
    CONCLUSIONS: SEDOHs varied significantly across rural communities regarding individual (race or health literacy), structural (insurance), and environmental-level factors (nutritious food or internet access). The high acceptability and feasibility of the SEDOH-88 shows it\'s potential utility in identifying targets for future disparity-reducing interventions.
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  • 文章类型: Journal Article
    背景:这项研究调查了邻里社会经济地位之间的关联,以困境社区指数(DCI)衡量,和结肠切除术后的短期结果。
    方法:利用马里兰州住院患者样本数据库(SID2018-2020),我们确定了DCI与结肠切除术后的术后结局之间的关联,包括住院时间,再入院,30天住院死亡率,和非常规放电。进行多因素回归分析以控制潜在的混杂因素。
    结果:在研究的13839名患者中,中位年龄为63岁,其中54.3%为女性,64.5%为择期入院。在36.9%的病例中进行了腹腔镜手术,平均住院时间为5天。困境社区的患者面临更高的急诊入院风险(OR:1.31),延长住院时间(OR:1.29),非常规放电(OR:1.36),和再入院(OR:1.33)。黑人患者的住院时间比白人患者长(OR:1.3)。尽管进行了调整,不同社区的院内死亡率没有显著差异.
    结论:我们的研究表明,居住在困境社区的患者面临更高的长期住院风险,非常规放电,结肠切除术后的再入院率。
    BACKGROUND: This study investigates the association between neighborhood socioeconomic status, measured by the Distressed Communities Index (DCI), and short-term outcomes following colon resection.
    METHODS: Utilizing the Maryland State Inpatient Sample database (SID 2018-2020), we determined the association between DCI and post-op outcomes following colon resection including length of stay, readmissions, 30-day in-hospital mortality, and non-routine discharges. Multivariate regression analysis was performed to control for potential confounding factors.
    RESULTS: Of the 13,839 patients studied, median age was 63, with 54.3 ​% female and 64.5 ​% elective admissions. Laparoscopic surgery was performed in 36.9 ​% cases, with a median hospital stay of 5 days. Patients in distressed communities faced higher risks of emergency admission (OR: 1.31), prolonged hospitalization (OR: 1.29), non-routine discharges (OR: 1.36), and readmission (OR: 1.33). Black patients had longer stays than White patients (OR: 1.3). Despite adjustments, in-hospital mortality did not significantly differ among neighborhoods.
    CONCLUSIONS: Our study reveals that patients residing in distressed neighborhoods face a higher risk of prolonged hospitalization, non-routine discharges, and readmission rate after colon resection.
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  • 文章类型: Journal Article
    背景:在评估隐睾的睾丸固定术的及时性时,在西班牙裔和非洲裔美国男性以及有公共保险的人中,健康差异很明显。自从这些数据公布以来,COVID-19大流行给我们的医疗保健系统带来了压力,并严重影响了儿科泌尿外科护理的提供。
    目的:我们试图评估某些群体在美国独立儿童医院大流行期间和之后诊断为隐睾后,在睾丸固定术进展中是否受到不成比例的影响。
    方法:使用PHIS数据库,对2018年1月至2022年12月期间接受睾丸固定术的≤5年儿科患者进行回顾性分析.排除标准包括早产,回缩睾丸,睾丸扭转.主要结果是睾丸固定术的年龄和接受及时睾丸固定术治疗隐睾的个体比例。
    结果:在研究期间,3140名≤5岁的患者因隐睾而接受睾丸固定术。与白人相比,非西班牙裔黑人和西班牙裔人及时进行睾丸固定术的可能性明显较小,并且在2.13和3.60个月后进行了睾丸固定术(p<0.01)。与COVID-19之前相比,在大流行期间,只有白人患者及时手术的患者比例更高,中位年龄显著更低(分别为p=0.01和p<0.01)。在学习期间,与有私人保险的患者相比,有公共保险的患者不太可能进行及时的睾丸固定术,并且在2.94个月后进行了睾丸固定术(p<0.01)。与大流行期间相比,大流行后,自那以后,公共保险患者中接受及时睾丸固定术的比例显着降低(p=0.04)。与其他地区相比,西方患者不太可能进行及时的睾丸固定术,并且在睾丸固定术时的年龄更高(p<0.01)。然而,在西部大流行期间,与COVID-19前后相比,及时手术的儿童比例更高(p<0.01)。
    结论:总体而言,无论保险状况如何,种族,或位置,相当比例的患者没有进行及时的睾丸固定术.在大流行期间,白人患者的中位年龄较低,接受及时睾丸固定术的比例增加,尽管睾丸的数量保持不变。在后COVID-19时代,公共保险患者的差距进一步加剧,此后接受及时睾丸固定术的比例明显较低。需要在美国各地做出具体努力,以增加所有男孩的及时睾丸固定术。
    结论:在COVID-19周围的时代,所有男孩的及时睾丸固定术进展仍然很低;某些群体似乎受到了更大的不利影响。
    BACKGROUND: When evaluating the timeliness of orchiopexy for cryptorchidism, health disparities are apparent among Hispanic and African American males and those with public insurance. Since the publication of these data, the COVID-19 pandemic has stressed our healthcare system and significantly affected the provision of pediatric urology care.
    OBJECTIVE: We sought to assess if certain groups were disproportionately affected in progression to orchiopexy after the diagnosis of cryptorchidism during and after the pandemic in US freestanding children\'s hospitals.
    METHODS: Using the PHIS database, pediatric patients ≤5 years who underwent orchiopexy between January 2018 and December 2022 were retrospectively analyzed. Exclusion criteria included prematurity, retractile testes, and testicular torsion. Primary outcomes were age at orchiopexy and the proportion of individuals undergoing timely orchiopexy for cryptorchidism.
    RESULTS: Over the study period 3140 patients ≤5 years old underwent orchiopexy for cryptorchidism. Non-Hispanic Blacks and Hispanics were significantly less likely to have timely orchiopexy and underwent orchiopexy 2.13 and 3.60 months later compared to whites (p < 0.01). As compared to pre-COVID-19, during the pandemic the proportion of patients who had timely surgery was higher and the median age was significantly lower (p = 0.01 and p < 0.01, respectively) in white patients only. Over the study period, patients with public insurance were less likely to have timely orchiopexy and underwent orchiopexy 2.94 months later (p < 0.01) than patients with private insurance. Compared to during the pandemic, post-pandemic a significantly lower proportion of publicly insured patients have since undergone timely orchiopexy (p = 0.04). Patients in the West were less likely to have timely orchiopexy and had a higher age at time of orchiopexy (p < 0.01) than other regions. However, in the West during the pandemic, the proportion of children who had timely surgery was higher compared to pre-and post-COVID-19 (p < 0.01).
    CONCLUSIONS: Overall, regardless of insurance status, race, or location, a significant proportion of patients did not undergo timely orchiopexy. During the pandemic white patients had a lower median age and an increased proportion underwent timely orchiopexy, despite the number of orchiopexies remaining constant. Disparities in the post-COVID-19 era have been further exacerbated for publicly insured patients, who a significantly lower proportion of have since undergone timely orchiopexy. Specific efforts are required across the United States to increase timely orchiopexy for all boys.
    CONCLUSIONS: Progression to timely orchiopexy remains low for all boys in the era surrounding COVID-19; certain groups appear to be more adversely affected.
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  • 文章类型: Journal Article
    背景:一些学术教科书以前传播过简单甚至不正确的种族概念。在普外科中传播此类想法可能会导致少数患者接受的护理质量差距。这项研究旨在确定普通外科教科书是否提供了对种族差异的透彻理解。
    方法:普外科文章取自Doody的列表,医学教育教科书的行业标准清单。技术指南,地图集,非普外科专业人员的书籍被排除在外.提取了提及种族和族裔群体之间医学差异的段落。进行了六种二元分类,基于段落(a)是否描述了减轻差异的干预措施;(b)解决了差异的环境中介;(c)描述了种族主义或歧视的贡献;(d)使用因果语言将种族与差异联系起来;(e)提到已知,遗传机制;和(f)直接提供参考。还提取了干预类型。计算了一个启发式量表,对分类a-c各给予一点,对分类d损失一点。三位作者进行了分类,原始协议和科恩的卡帕被用来评估评估者间的可靠性。
    结果:来自Doody列表的13本教科书包含511段,讨论种族/族裔群体之间的医学差异。在段落中,25%的人讨论过白人,22%黑人/非洲裔美国人,19%的亚洲人,9%的拉丁裔,4%的犹太人/阿什肯纳齐人,3%美洲原住民,其他18%。15段(2.9%)使用语言表明种族是造成医学差异的原因,只有两个人明确讨论了种族主义或歧视。大多数段落(370,72.3%)的评分为0。120人(23.5%)获得1的量表,8人(1.2%)获得2的量表,零人获得3的量表。平均通过量表为0.24,并且不随时间变化(回归系数-0.006/年,p=0.538)。所有类别的协议为91.2%,总体Kappa为0.62。
    结论:普外科教科书没有为读者提供对健康差异的科学透彻理解。教授更全面的概念,包括系统性原因和种族主义的作用,可以防止少数患者预后不良的反身关联。未来的版本应该包括这些细节,在独立的地方讨论差异,综合部分。
    BACKGROUND: Some academic textbooks have previously disseminated simplistic or even incorrect conceptions of race. Propagation of such ideas in General Surgery could contribute to gaps in quality of care received by minority patients. This study aims to determine whether General Surgery textbooks provide a thorough understanding of racial disparities.
    METHODS: General Surgery texts were drawn from Doody\'s list, an industry-standard list of textbooks for medical education. Technical guides, atlases, and books for non-General Surgery professionals were excluded. Passages mentioning medical differences amongst racial and ethnic groups were extracted. Six binary classifications were made, based on whether passages (a) described interventions to alleviate difference; (b) addressed environmental mediators of difference; (c) described the contribution of racism or discrimination; (d) used causal language to connect race to difference; (e) referred to known, heritable genetic mechanisms; and (f) directly provided a reference. Types of intervention were also extracted. A heuristic scale was calculated granting one point each for classifications a-c and losing one point for classification d. Three authors performed classifications, and raw agreement and Cohen\'s kappa were used to assess inter-rater reliability.
    RESULTS: Thirteen textbooks from Doody\'s list contained 511 passages discussing medical differences among racial/ethnic groups. Among passages, 25% discussed white people, 22% Black people/African Americans, 19% Asians, 9% Latinos, 4% Jewish/Ashkenazi people, 3% Native Americans, and 18% other. Fifteen passages (2.9%) used language indicating race was the cause of medical difference, and only two explicitly discussed racism or discrimination. Most passages (370, 72.3%) received a scale of 0. 120 (23.5%) received a scale of 1, eight (1.2%) received a scale of 2, and zero received a scale of 3. The mean passage scale was 0.24 and is not changing with time (regression coefficient -0.006/year, p = 0.538). Agreement was 91.2% across all categories and overall Kappa was 0.62.
    CONCLUSIONS: General Surgery textbooks do not provide readers with scientifically thorough understanding of health disparities. Teaching more comprehensive conceptions, including systemic causes and the role of racism, may prevent reflexive association of minority patients with poor outcomes. Future editions should include these details where disparities are discussed in an independent, comprehensive section.
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  • 文章类型: Journal Article
    目的:结肠癌(CC)仍然是全球癌症相关死亡的主要原因,结肠切除术代表护理标准。然而,延迟切除对生存结局的影响仍存在争议.我们在CC患者的全国队列中评估了手术时间与10年生存率之间的关系。
    方法:这项回顾性队列研究在2004-2020年国家癌症数据库中确定了所有接受I-III期CC结肠切除术的成年人。在诊断后<7天需要新辅助治疗或紧急切除的患者被排除在外。在对手术时间和10年生存率之间的关系进行调整分析后,将患者分为早期(<25天)和延迟(≥25天)队列。生存在1-,5-,通过Kaplan-Meier分析和Cox比例风险模型评估了10年,调整年龄,性别,种族,收入四分位数,保险范围,Charlson-Deyo合并症指数,疾病阶段,肿瘤的位置,接受辅助化疗,以及医院类型,location,和案件量。
    结果:在165,991名患者中,84,665(51%)被归类为早期和81,326(49%)延迟。风险调整后,延迟切除与相似的1年相关[风险比(HR)1.01,95%置信区间(CI)0.97-1.04,P=0.72],但低于5年(HR1.24,CI1.22-1.26;P<0.001)和10年生存率(HR1.22,CI1.20-1.23;P<0.001)。黑人种族[调整后的优势比(AOR)1.36,CI1.31-1.41;P<0.001],医疗补助保险范围(AOR1.34,CI1.26-1.42;P<0.001),在高容量医院的护理(AOR1.12,95CI1.08-1.17;P<0.001)与延迟切除的可能性更大相关。
    结论:诊断后≥25天接受切除的CC患者1年表现相似,但5年和10年生存率较差,与那些在25天内接受手术的人相比。社会经济因素,包括种族和医疗补助保险,与延迟切除的可能性更大。需要努力平衡适当的术前评估与加速切除,以优化患者的预后。
    OBJECTIVE: Colon cancer (CC) remains a leading cause of cancer-related mortality worldwide, for which colectomy represents the standard of care. Yet, the impact of delayed resection on survival outcomes remains controversial. We assessed the association between time to surgery and 10-year survival in a national cohort of CC patients.
    METHODS: This retrospective cohort study identified all adults who underwent colectomy for Stage I-III CC in the 2004-2020 National Cancer Database. Those who required neoadjuvant therapy or emergent resection < 7 days from diagnosis were excluded. Patients were classified into Early (< 25 days) and Delayed (≥ 25 days) cohorts after an adjusted analysis of the relationship between time to surgery and 10-year survival. Survival at 1-, 5-, and 10-years was assessed via Kaplan-Meier analyses and Cox proportional hazard modeling, adjusting for age, sex, race, income quartile, insurance coverage, Charlson-Deyo comorbidity index, disease stage, location of tumor, receipt of adjuvant chemotherapy, as well as hospital type, location, and case volume.
    RESULTS: Of 165,991 patients, 84,665 (51%) were classified as Early and 81,326 (49%) Delayed. Following risk adjustment, Delayed resection was associated with similar 1-year [hazard ratio (HR) 1.01, 95% confidence interval (CI) 0.97-1.04, P = 0.72], but inferior 5- (HR 1.24, CI 1.22-1.26; P < 0.001) and 10-year survival (HR 1.22, CI 1.20-1.23; P < 0.001). Black race [adjusted odds ratio (AOR) 1.36, CI 1.31-1.41; P < 0.001], Medicaid insurance coverage (AOR 1.34, CI 1.26-1.42; P < 0.001), and care at high-volume hospitals (AOR 1.12, 95%CI 1.08-1.17; P < 0.001) were linked with greater likelihood of Delayed resection.
    CONCLUSIONS: Patients with CC who underwent resection ≥ 25 days following diagnosis demonstrated similar 1-year, but inferior 5- and 10-year survival, compared to those who underwent surgery within 25 days. Socioeconomic factors, including race and Medicaid insurance, were linked with greater odds of delayed resection. Efforts to balance appropriate preoperative evaluation with expedited resection are needed to optimize patient outcomes.
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  • 文章类型: Journal Article
    目的:口咽鳞状细胞癌(OPSCC)呈上升趋势。该手稿旨在探讨OPSCC手术治疗中的种族差异。
    方法:在癌症数据库中查询了2004年至2017年诊断为OPSCC的患者。单变量和多变量逻辑回归用于评估患者种族/民族之间的关联,手术治疗,以及缺乏手术的原因。
    结果:37306例(74.3%)患者没有接受手术,而12901例(25.7%)患者有。非西班牙裔黑人(NHB)患者接受手术的可能性低于其他种族(17.9%vs.26.5%;p<0.0001)。在临床讨论中,亚洲人,美洲原住民,夏威夷,太平洋岛民(ANAHPI)和未知种族组更有可能在推荐时直接拒绝手术(2.5%vs.1.5%;p=0.015)。
    结论:OPSCC的治疗存在种族差异。NHB患者实际上接受OPSCC手术治疗的可能性较小,而其他患者更有可能在接受手术时直接“拒绝”。
    Oropharyngeal squamous cell carcinoma (OPSCC) has been rising. This manuscript looks to explore racial disparities in the surgical management of OPSCC.
    A cancer database was queried for patients with OPSCC diagnosed from 2004 to 2017. Univariate and multivariable logistic regressions were used to evaluate associations between patient race/ethnicity, surgical treatment, and reasons for lack of surgery.
    37 306 (74.3%) patients did not undergo surgery, while 12 901 (25.7%) patients did. Non-Hispanic black (NHB) patients were less likely to undergo surgery than other races (17.9% vs. 26.5%; p < 0.0001). In clinical discussions, the Asian, Native American, Hawaiian, Pacific Islander (ANAHPI), and unknown race group was more likely to directly refuse surgery when recommended (2.5% vs. 1.5%; p = 0.015).
    Racial differences exist in treatment for OPSCC. NHB patients are less likely to actually undergo surgical management for OPSCC, while other patients are more likely to directly \"refuse\" surgery outright when offered.
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