皮层下通路被认为是为了促进恐惧信息的传播而进化的,但是缺乏它在人类中存在的直接证据。近年来,快速,预先注意,前意识的恐惧处理已经被证明,通过挑战恐惧处理中规范皮层途径的必要性,为皮层下途径的存在提供间接支持。然而,直接支持还需要皮质下区域参与恐惧处理的证据.为了解决这个问题,在这里,我们研究恐惧处理是否反映了假设的皮层下通路中皮层下结构的特征。使用单目/双目范式,实验1展示了恐惧但不中性面部处理的同眼优势,这表明恐惧处理依赖于主要存在于皮质下的单眼神经元。实验2和3进一步显示了对短波长刺激的不敏感和恐惧处理中的鼻-颞半场不对称性,两者都是上丘的功能特征,皮层下通路的关键枢纽.此外,所有三个实验都揭示了恐惧处理的低空间频率选择性,与通过皮质下神经元的大细胞输入一致。这些结果表明,皮质下结构选择性地参与了恐惧处理,which,以及自动处理恐惧的间接证据,提供了一个更完整的图像的存在的皮层下途径的恐惧处理在人类。(PsycInfo数据库记录(c)2024APA,保留所有权利)。
A subcortical pathway is thought to have evolved to facilitate fear information transmission, but direct evidence for its existence in humans is lacking. In recent years, rapid, preattentive, and preconscious fear processing has been demonstrated, providing indirect support for the existence of the subcortical pathway by challenging the necessity of canonical cortical pathways in fear processing. However, direct support also requires evidence for the involvement of subcortical regions in fear processing. To address this issue, here we investigate whether fear processing reflects the characteristics of the subcortical structures in the hypothesized subcortical pathway. Using a monocular/dichoptic paradigm, Experiment 1 demonstrated a same-eye advantage for fearful but not neutral face processing, suggesting that fear processing relied on monocular neurons existing mainly in the subcortex. Experiments 2 and 3 further showed insensitivity to short-wavelength stimuli and a nasal-temporal hemifield asymmetry in fear processing, both of which were functional characteristics of the superior colliculus, a key hub of the subcortical pathway. Furthermore, all three experiments revealed a low spatial frequency selectivity of fear processing, consistent with magnocellular input via subcortical neurons. These results suggest a selective involvement of subcortical structures in fear processing, which, together with the indirect evidence for automatic fear processing, provides a more complete picture of the existence of a subcortical pathway for fear processing in humans. (PsycInfo Database Record (c) 2024 APA, all rights reserved).