Sterilization Reversal

灭菌逆转
  • 文章类型: Meta-Analysis
    目的:20%到30%的接受过输卵管结扎术的妇女对她们的决定感到后悔。这些妇女恢复生育能力的替代方法是体外受精或输卵管再吻合。本文通过荟萃分析进行了系统评价,以评估先前接受过输卵管结扎术的患者的输卵管再通手术疗效的当前证据。
    方法:搜索是在科学世界(WOS)数据库中进行的,Cochrane图书馆和ClinicalTrials.gov使用关键字“输卵管逆转”记录,“输卵管再吻合”和“输卵管吻合”。审查是由两位作者进行的。对22项研究的数据进行了评估,包括超过14,113名接受研究手术的患者,遵循严格的纳入标准:纳入2012年1月至2022年6月期间发表的英文文章,样本量大于10例患者.进行了随机效应荟萃分析。
    结果:发现吻合后的总体妊娠率为65.3%(95%CI:61.0-69.6)。至少有一次活产的妇女的百分比,被称为出生率,为42.6%(95%CI:34.9-51.4)。还检查了手术后的不良结局:接受手术的妇女中观察到的流产率为9.4%(95%CI:7.0-11.7),总体异位妊娠率为6.8%(95%CI:4.6-9.0)。在区分手术入路时,没有发现结果之间的差异:剖腹手术,腹腔镜检查,或机器人辅助手术。患者的年龄被确定为生育能力恢复的最重要决定因素。最后,当比较输卵管逆转与体外受精的结果时,逆转手术似乎对35岁以上的患者更有利,虽然35岁以下的患者的结果相似,但需要更多的数据来评估这一发现。
    结论:因此,现有的文献综述表明,输卵管结扎后的外科吻合术是一种具有相关成功率的可重复技术,由全球多个专家组执行。
    OBJECTIVE: Between 20% and 30% of women who have undergone tubal ligation regret their decision. The alternative to regain fertility for these women is either in vitro fertilization or tubal re-anastomosis. This article presents a systematic review with meta-analysis to assess the current evidence on the efficacy of tubal recanalization surgery in patients who have previously undergone tubal ligation.
    METHODS: The search was conducted in the World of Science (WOS) database, The Cochrane Library and ClinicalTrials.gov record using the keywords \"tubal reversal\", \"tubal reanastomosis\" and \"tubal anastomosis\". The review was carried out by two of the authors. Data from 22 studies were evaluated, comprising over 14,113 patients who underwent the studied surgery, following strict inclusion criteria: articles published between January 2012 and June 2022, in English and with a sample size bigger than 10 patients were included. A random-effects meta-analysis was performed.
    RESULTS: The overall pregnancy rate after anastomosis was found to be 65.3 % (95 % CI: 61.0-69.6). The percentage of women who had at least one live birth, known as the birth rate, was 42.6 % (95 % CI: 34.9-51.4). Adverse outcomes after surgery were also examined: the observed abortion rate among women who underwent surgery was 9.4 % (95 % CI: 7.0-11.7), and the overall ectopic pregnancy rate was 6.8 % (95 % CI: 4.6-9.0). No differences were found between the outcomes when differentiating surgical approaches: laparotomy, laparoscopy, or robotic-assisted surgery. The patient\'s age was identified as the most significant determining factor for fertility restoration. Finally, when comparing the results of tubal reversal with in vitro fertilization, reversal procedures appear more favorable for patients over 35 years old, while the results are similar for patients under 35 years old, but more data is needed to evaluate this finding.
    CONCLUSIONS: Therefore, the available literature review demonstrates that surgical anastomosis following tubal ligation is a reproducible technique with relevant success rates, performed by multiple expert groups worldwide.
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  • 文章类型: Journal Article
    5%至20%的女性后悔进行输卵管结扎术。这些妇女通常在其他方面具有生育能力,并且比其他经历不孕症的患者有更好的怀孕机会,无论是体外受精还是输卵管手术后。历史上,输卵管吻合术长期以来一直通过剖腹手术进行显微外科手术,这提供了非常高的精度,但与一定程度的发病率有关。体外受精和腹腔镜的并行发展有助于减少输卵管手术的适应症。由于所需缝合线的数量和精度,腹腔镜方法具有挑战性。机器人辅助腹腔镜方法可以降低手术难度并改善该技术的可及性。我们已经描述了10步机器人辅助腹腔镜灭菌后输卵管再吻合的技术。由于摄像机的稳定性,机器人辅助腹腔镜为灭菌后进行输卵管再吻合提供了有利条件。运动的精度,和关节的振幅。
    Five to 20% of women regret having a tubal ligation. These women are generally otherwise fertile and have a better chance of pregnancy than other patients experiencing infertility, whether by in vitro fertilization or after tubal surgery. Historically, tubal anastomosis surgery has long been performed by microsurgery through laparotomy, which provided very high precision but was associated with some degree of morbidity. The parallel development of in vitro fertilization and laparoscopy have contributed to reducing the indications for tubal surgery. The laparoscopic approach is challenging because of the number and precision of the sutures needed. The robot-assisted laparoscopic approach may reduce the surgical difficulty and improve the accessibility of this technique. We have described the technique of tubo-tubal reanastomosis after sterilization with robot-assisted laparoscopy in 10 steps. Robot-assisted laparoscopy provides favourable conditions for performing tubo-tubal reanastomosis after sterilization due to the camera stability, precision of movement, and amplitude of articulations.
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  • 文章类型: Case Reports
    目的:显示三维腹腔镜输卵管再吻合中的减少缝线技术。
    方法:使用视频逐步演示该过程。
    方法:腹腔镜输卵管反灭菌术要求高精度,需要技术和经验。传统上,使用6-0至8-0可吸收缝线的4至6个中断模式用于腹腔镜输卵管再吻合。我们在放大的3D视图下使用了更少和更大的缝线来执行手术。
    方法:我们介绍了一个42岁女性的案例,gravida3,para3,10年前在剖宫产期间接受了输卵管绝育。术前子宫输卵管造影(HSG)显示双侧远端输卵管闭塞。该程序从浆膜下注射稀释的血管加压素开始,在近端和远端以及输卵管系膜中进行,以促进解剖和止血。在横切输卵管残端和去除瘢痕组织后,我们使用3Fr输尿管导管作为支架以促进缝合。在6、2和10个时钟部位使用了三个中断的4-0单锁骨缝合线缝合输卵管粘膜层和肌肉层。我们进行了双侧壶腹-壶腹吻合术。这些管成功地重新吻合,通过在手术结束时进行的染色观察证实了通畅(图1).手术持续了71分钟。手术失血量小于50ml。术后1个月HSG证实右输卵管未闭。患者在手术后8个月成功怀孕。
    结论:我们的经验表明3D腹腔镜手术使用减少缝线进行输卵管再吻合的可行性。该技术减轻了对输卵管的损伤。手术时间,住院,术后粘连明显低于常规方法,成功率相当。
    OBJECTIVE: To show the technique of reduced sutures in 3D laparoscopic tubal reanastomosis.
    METHODS: Step-by-step demonstration of the procedure using video.
    METHODS: Laparoscopic tubal sterilization reversal demands high precision and requires both skill and experience. Conventionally, 4 to 6 interrupted patterns using 6-0 to 8-0 absorbable sutures are used for laparoscopic tubal reanastomosis. We used fewer and larger sutures under a magnified 3D view to perform the procedure.
    METHODS: We presented a case of a 42-year-old woman, gravida 3, para 3, who underwent tubal sterilization during Cesarean section 10 years ago. Preoperative hysterosalpingography (HSG) showed bilateral distal tubal occlusion. The procedure started with the subserosal injection of diluted vasopressin in both proximal and distal ends and in the mesosalpinx to facilitate dissection and hemostasis. After transection of tubal stump and removal of scar tissue, we used a 3 Fr ureteral catheter as the stent to facilitate suturing. Three interrupted 4-0 monocryl sutures were used for suturing both tubal mucosal and muscular layers at 6, 2, and 10 o\'clock sites. We performed bilateral ampullo-ampullary reanastomosis. The tubes were successfully reanastomosed, and patency was confirmed by chromotubation performed at the end of the procedure (Figure 1). The operation lasted for 71 minutes. The operative blood loss was less than 50 ml. Patent right fallopian tube was confirmed on postoperative HSG 1 month later. The patient had a successful pregnancy 8 months after the operation.
    CONCLUSIONS: Our experience shows the feasibility of 3D laparoscopy for tubal reanastomosis using reduced sutures. The technique alleviates the damage to the fallopian tube. The operative time, hospital stay, and postoperative adhesions were significantly lower than the conventional method with a comparable success rate.
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  • 文章类型: Journal Article
    女性绝育后的遗憾在美国并不少见。在辅助生殖技术(ART)发展之前,对于对生育感兴趣的患者,手术逆转绝育是唯一的选择.该手术于1972年首次进行,此后多年来由妇科外科医生改进。随着体外受精(IVF)的普及,对灭菌逆转的兴趣已经减弱。然而,在输卵管结扎后寻求妊娠的患者中,绝育逆转应仍然是重要的选择。
    由于报告生育结果的固有差异,IVF和绝育逆转之间的直接比较具有挑战性。然而,绝育逆转可能会优化年轻女性的生育能力,而IVF可能对老年女性更有效。绝育逆转的手术方法可以是剖腹手术,腹腔镜或机器人。临床决策应包括考虑异位妊娠的风险,从灭菌到逆转的间隔,灭菌程序的类型,计划吻合部位和预计剩余输卵管长度。
    在试管婴儿时代,灭菌逆转在恢复生育力的管理中仍然占有一席之地。提高对灭菌逆转作用的认识是改善下一代生殖外科医生在此过程中获得适当培训的第一步。
    Regret after female sterilization is not uncommon in the United States. Prior to the development of assisted reproductive technology (ART), surgical reversal of sterilization was the only option for patients interested in fertility. First performed in 1972, this procedure has since been refined over the years by gynaecologic surgeons. With in-vitro fertilization (IVF) gaining popularity, interest in sterilization reversal has waned. However, sterilization reversal should remain an important option in patients seeking pregnancy after tubal ligation.
    A direct comparison between IVF and sterilization reversal is challenging due to inherent differences in reporting fertility outcomes. However, sterilization reversal may optimize fertility in younger women, whereas IVF may be more effective in older women. The surgical approach to sterilization reversal can be laparotomic, laparoscopic or robotic. Clinical decision making should include consideration of the risk of ectopic pregnancy, interval from sterilization to reversal, type of sterilization procedure, planned anastomotic site and projected remaining tubal length.
    In the era of IVF, sterilization reversal still has a place in the management in restoring fertility. Creating awareness of the role of sterilization reversal is the first step in improving access to adequate training in this procedure for the next generation of reproductive surgeons.
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  • 文章类型: Journal Article
    根据当代女性绝育时的年龄估计绝育后悔的风险。
    我们对2015-2017年和2017-2019年全国家庭增长调查的横截面数据进行了回顾性分析,女性受访者档案,估计经历绝育后悔的女性比例。描述性统计数据被用来描述人口和遗憾的比例。灭菌遗憾被定义为经历了灭菌逆转或肯定想要灭菌逆转的人。使用多变量逻辑回归模型来评估与绝育后悔的关联。
    共有1,549名接受绝育的妇女被纳入分析;8%的年龄为21-30岁,92%的人年龄超过30岁。在参与者中,16.9%确定为黑色,22.0%是西班牙裔,57.2%为白色。大多数(58.4%)在21至30岁之间接受了输卵管绝育手术。后悔的累积比例为10.2%(21-30岁接受绝育的妇女为12.6%,30岁以上接受绝育的妇女为6.7%)。在控制包括年龄在内的协变量后,种族,奇偶校验,教育程度,和绝育的医学原因,唯一与后悔有统计学显著关联的变量是访谈时的年龄(P<.001).随着女性年龄的增长,他们不太可能报告绝育遗憾。
    年轻女性经历更多的绝育遗憾。随着女性年龄的增长,灭菌后悔减少。关于绝育的咨询应该揭示未来欲望的不可预测性,但是年龄本身不能成为进行绝育的障碍。
    To estimate the risk of sterilization regret based on age at the time of sterilization in a contemporary group of women.
    We conducted a retrospective analysis of cross-sectional data from the 2015-2017 and 2017-2019 National Survey of Family Growth, Female Respondent Files, to estimate the proportion of women who experience sterilization regret. Descriptive statistics were used to describe the population and the proportion with regret. Sterilization regret was defined as someone who either underwent sterilization reversal or who definitely wanted sterilization reversal. Multivariable logistic regression models were used to assess associations with sterilization regret.
    A total of 1,549 women who underwent sterilization were included in the analysis; 8% were aged 21-30 years, and 92% were aged older than 30 years. Of the participants, 16.9% identified as Black, 22.0% as Hispanic, and 57.2% as White. Most (58.4%) underwent a tubal sterilization procedure between age 21 and 30 years. The cumulative proportion of regret was 10.2% (12.6% for women who underwent sterilization at age 21-30 years and 6.7% for those who underwent sterilization at older than age 30 years). After controlling for covariates including age, race, parity, educational attainment, and medical reason for sterilization, the only variable that had a statistically significant association with regret was age at the time of the interview (P<.001). As women got older, they were less likely to report sterilization regret.
    Younger women experience more sterilization regret. As women get older, sterilization regret decreases. Counseling about sterilization should reveal the unpredictability of future desire, but age alone must not be a barrier to performing sterilization.
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  • 文章类型: Journal Article
    BACKGROUND: Tubal reanastamosis offers hope to conceive again. However, there are many factors that affect the success of this procedure. In our study we aimed to compare the pregnancy rates of the surgical methods used for tubal reanastamosis in pregnancy requested after tubal sterilization.
    METHODS: In our study we compared the rates of pregnancies after reanastamosis retrospectively in female patients under the age of 40 who underwent reanastamosis between 2010 and 2019 with laparotomic, laparoscopic and robotic methods. A single layer of 4 quadrant 6/0 number polydioxanone absorbable sutures were used in all surgical methods. A similar surgical technique was used.
    RESULTS: In surgical methods (laparotomy, laparoscopy, and robotics), there was a statistical difference between the three groups in terms of operation times of surgical methods used for tubal reanastamosis (p < 0.05). Laparotomy, laparoscopy, and robotics pregnancy rates were 52.6% (n = 41), 67.3% (n = 37), 61.2% (n = 63), respectively. There was no statistical difference between groups in terms of pregnancy rates. However, odds ratio (OR) values of the laparoscopy group and robotics group probability of conception were 1.536 (95% confidence interval [CI], 0.813-2.898), 1.111 (95% CI, 0.656-1.879) higher, respectively.
    CONCLUSIONS: Although there is no statistical difference between the surgical methods used for tubal reanastamosis, we think that the laparoscopic surgical method may be preferable due to the shorter hospital stay. We think that the previous method of bilateral tubaligastion (BTL), the site of reanastasis, and the time between BTL and reanastomosis were effective in pregnancy success.
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  • DOI:
    文章类型: Case Reports
    输卵管再吻合或输卵管逆转,一种用于逆转输卵管绝育的手术方法,对于出于各种原因希望恢复生育能力的妇女来说,这可能是一种选择。一个38岁的中国女人,gravida2,para2(均通过剖宫产分娩)提交给我们的门诊妇科诊所,要求双侧输卵管再通。在排除其他不孕原因后,行腹腔镜输卵管再吻合术。这里,我们介绍了腹腔镜输卵管再吻合术迅速导致宫内妊娠的技巧和技术,在学期交付的。腹腔镜输卵管再吻合术是一种公认的手术,预后良好,正如文献报道的那样。对于希望在输卵管绝育后怀孕的女性,有必要提出手术和体外受精的选择。
    Tubal reanastomosis or tubal reversal, a surgical method used to reverse tubal sterilization, may be an option for women who for various reasons wish to reestablish their fertility. A 38-year-old Chinese woman, gravida 2, para 2 (both delivered through cesarean section) presented to our outpatient gynecology clinic requesting bilateral tubal recanalization. After other causes of infertility were excluded, laparoscopic tubal reanastomosis was performed. Here, we present our tips and techniques for laparoscopic tubal reanastomosis that rapidly resulted in an intrauterine pregnancy, which delivered at term. Laparoscopic tubal reanastomosis is a well-established procedure with good prognosis, as reported in the literature. For women who wish to become pregnant after tubal sterilization, it is necessary to present the option of surgery as well as in vitro fertilization.
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  • 文章类型: Journal Article
    This document reviews surgical options for reparative tubal surgery and the factors that must be considered when deciding between surgical repair and in vitro fertilization. This document replaces the document of the same name, last published in 2012 (Fertil Steril 2015;103:e37-43). This document reviews surgical options for reparative tubal surgery and the factors that must be considered when deciding between surgical repair and in vitro fertilization.
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  • 文章类型: Journal Article
    BACKGROUND: Tubal anastomosis has similar pregnancy rates regardless of approach. Historically, robotic anastomosis has been associated with increased cost and operative time. We sought to perform a contemporary study of these metrics.
    METHODS: One hundred and nine patients were identified who underwent robotic-assisted laparoscopic tubal anastomosis. Retrospective analysis of medical records was performed. Phone survey was conducted.
    RESULTS: The mean operative time decreased from 140.7 ± 27.0 min in 2013 to 60.0 ± 9.1 min in 2018, with significant downward trend (p < 0.001). The mean cost was $7153.46 ± $1484.41. The pregnancy rate was 59% (35/59), and tubal patency rate was 81% (42/52). Seventy-two percent of patients under 37 years became pregnant.
    CONCLUSIONS: There is significant improvement in operative time of robotic-assisted tubal anastomosis with surgical experience. Robotic tubal anastomosis outperformed historical metrics of laparoscopy and laparotomy with regard to operative time and cost in this series.
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  • 文章类型: Journal Article
    On the occasion of the 45th anniversary of the introduction of microsurgery in urology, the author describes the historical development of urologic microsurgery in Germany, with special reference to vasectomy reversal. Together with contemporary witnesses, a critical historical review is drawn and the current status is analyzed as well as an outlook is given.
    UNASSIGNED: Das 45-jährige Jubiläum der Einführung der Mikrochirurgie in die Urologie nimmt der Autor zum Anlass, um einen Überblick über die historische Entwicklung der urologischen Mikrochirurgie in Deutschland unter besonderer Berücksichtigung der Refertilisierungschirurgie zu geben. Unter Einbeziehung von Zeitzeugen gelingt eine fast lückenlose Darstellung der Schwerpunkte dieser Entwicklung. Eine kritische Bilanz der aktuellen Situation und ein Ausblick zur Zukunft der Mikrochirurgie in der deutschen Urologie bilden den Abschluss.
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