背景:坏死性小肠结肠炎(NEC)和颅内出血是新生儿期的严重紧急情况。这两者似乎并不相关。然而,我们的报告提示,足月新生儿脑实质出血可能通过脑-肠轴改变肠功能,使患者面临NEC风险.
方法:我们介绍一例足月新生儿自发性脑实质出血病例,该病例在第15天发生早期NEC。
结论:可能认为脑实质出血是NEC出现的危险因素。临床医生应高度谨慎的NEC在经历过实质性出血的婴儿。本文首次讨论足月新生儿实质性出血与NEC的关系。
BACKGROUND: Necrotizing enterocolitis (NEC) and intracranial hemorrhage are severe emergencies in the neonatal period. The two do not appear to be correlated. However, our report suggests that parenchymal brain hemorrhage in full-term newborns may put patients at risk for NEC by altering intestinal function through the brain-gut axis.
METHODS: We present a case of spontaneous parenchymal cerebral hemorrhage in a full-term newborn who developed early-stage NEC on Day 15.
CONCLUSIONS: It is possible to consider brain parenchymal hemorrhage as a risk factor for the appearance of NEC. Clinicians should be highly cautious about NEC in infants who have experienced parenchymal hemorrhage. This article is the first to discuss the relationship between parenchymal hemorrhage and NEC in full-term newborns.