背景:下背部和颈部疼痛是常见的肌肉骨骼疾病,有多种治疗选择。印度的传统医疗系统,被称为阿尤什(阿育吠陀,瑜伽和自然疗法,Unani,西达,Sowa-Rigpa和同病)提供了一系列干预措施,并被广泛使用。鉴于Ayush干预腰椎和颈椎病后不良事件的文献有限,我们综合了证据并估计了报告不良事件的研究比例.
方法:我们系统地搜索了从生物医学和多学科摘要和引文数据库以及Ayush特定存储库(从成立到2021年4月)的所有已发布文档。我们根据纳入标准选择了研究,并提取了信息,遵守PRISMA准则。我们系统地回顾了选定研究的定性证据。
结果:在选定的113项研究中,大多数(94%)是介入研究,包括77篇(68.1%)期刊论文和35篇(31%)学术论文。在Ayush系统中,相当比例来自阿育吠陀(32.7%),其次是西达(24.8%),瑜伽(22.1%)Unani(15.9%)和同种病(4.4%)。几乎四分之三的研究是关于腰椎病的(65%;n=74),其次是颈椎病(31%;n=35),其余四个包括两个。113项研究中有13%描述了不良事件[瑜伽=9.7%;Unani=1.8%和同种病=1.8%]。与颈椎病(2.7%)相比,腰椎研究中报告的不良事件更多(9.7%)。干预的性质是非药物干预(10.6%;n=12),药理学(n=2;1.8%)或联合(n=1;0.9%)。
结论:8项研究中只有1项报告了在Ayush干预颈椎和腰椎病后出现的不良事件。不良事件可能存在一定程度的漏报,需要进一步探索。PROSPERO注册IDCRD42020167433。
BACKGROUND: Low back and neck pain are common musculoskeletal disorders with multiple treatment options. India\'s traditional medical systems, known as Ayush (Ayurveda, Yoga and Naturopathy, Unani, Siddha, Sowa-Rigpa and Homoeopathy) offer range of interventions and are widely used. In view of limited documentation of adverse events following Ayush interventions for lumbar and cervical
spondylosis, we synthesized evidence and estimated proportion of studies reporting adverse events.
METHODS: We systematically searched all published documents from biomedical and multidisciplinary abstract and citation databases and Ayush-specific repositories from their inception to April 2021. We selected studies as per inclusion criteria and extracted information, adhering to PRISMA guidelines. We systematically reviewed the qualitative evidence form the selected studies.
RESULTS: Majority (94%) of the selected 113 studies were interventional studies and included 77 (68.1%) journal articles and 35 (31%) academic dissertations. Among the Ayush systems, considerable proportion was from Ayurveda (32.7%), followed by Siddha (24.8%), Yoga (22.1%), Unani (15.9%) and Homoeopathy (4.4%). Almost three-fourths of the studies were on lumbar
spondylosis (65%; n = 74), followed by cervical
spondylosis (31%; n = 35), and the remaining four included both. Thirteen percent of the 113 studies described adverse events [Yoga = 9.7%; Unani = 1.8% and Homoeopathy = 1.8%]. More adverse events were reported among the studies on lumbar (9.7%) than cervical
spondylosis (2.7%). The nature of interventions were non-pharmacological (10.6%; n = 12), pharmacological (n = 2; 1.8%) or combined (n = 1; 0.9%).
CONCLUSIONS: Only one in eight studies reported any adverse event following Ayush interventions for cervical and lumbar
spondylosis. There could be certain degree of underreporting of adverse events and requires further exploration. PROSPERO Registration ID CRD42020167433.