背景:脊柱骨盆参数可能导致退行性腰椎滑脱的发展。然而,以前的研究显示出相互矛盾的结果;一些研究发现这些参数与退行性腰椎滑脱存在显著关系,而其他人没有。以前,没有荟萃分析有关脊柱骨盆排列与退行性腰椎滑脱之间的关联.这项荟萃分析旨在确定脊柱骨盆对准与退行性腰椎滑脱之间的关联。
方法:系统评价和荟萃分析基于系统评价和荟萃分析(PRISMA)的选定项目报告方法。使用PubMed进行文献检索,EMBASE,ScienceDirect,科克伦,谷歌学者。方法学质量基于医疗保健研究与质量局(AHRQ)质量检查方法的横断面清单和用于队列研究的纽卡斯尔-渥太华量表(NOS)。使用Rev-Man5.3进行统计分析。根据种族和研究设计进行亚组分析,以确定种族关系和异质性。
结果:共获得3236篇。其中,我们发现骨盆发病率(平均差异[MD]=11.94[1.81-22.08],P=0.02),骨盆倾斜(MD=4.47[0.81-8.14]),P=0.02),和年龄(MD=11.94[1.81-22.08],P=0.02)与退行性腰椎滑脱的发展有关。
结论:这项荟萃分析证明骨盆发病率,骨盆倾斜,和年龄与退行性腰椎滑脱有关。
BACKGROUND: Spinopelvic parameter may result in the development of degenerative spondylolisthesis. However, previous studies show conflicting results; some found a significant relationship of some of these parameters with degenerative spondylolisthesis, while others did not. Previously, there was no meta-analysis regarding the association between spinopelvic alignment and degenerative spondylolisthesis. This meta-analysis aims to determine the association between spinopelvic alignment and degenerative spondylolisthesis.
METHODS: Systematic reviews and meta-analyses are based on the selected item reporting method for systematic review and meta-analysis (PRISMA). A literature search was performed using PubMed, EMBASE, ScienceDirect, Cochrane, and Google Scholar. Methodological quality is based on the cross-sectional checklist of the Agency for Healthcare Research and Quality (AHRQ) quality check methodology and the Newcastle-Ottawa scale (NOS) for cohort studies. Statistical analysis was performed using Rev-Man 5.3. Subgroup analyses were performed based on ethnicity and study design to ascertain racial relations and heterogeneity.
RESULTS: A total of 3236 articles were obtained. Of these, we found that pelvic incidence (mean difference [MD] = 11.94 [1.81-22.08], P = 0.02), pelvic tilt (MD = 4.47 [0.81-8.14]), P = 0.02), and age (MD = 11.94 [1.81-22.08], P = 0.02) were associated with the development of degenerative spondylolisthesis.
CONCLUSIONS: This meta-analysis proves that pelvic incidence, pelvic tilt, and age are associated with degenerative spondylolisthesis.