方法:前瞻性,单中心研究。
目的:评估经验证的术中出血严重程度量表(VIBe)在胸腰椎手术中的临床相关性。
方法:18至88岁接受择期减压的成年患者,仪器仪表,在提供知情同意并获得书面同意后,前瞻性纳入胸腰椎融合术.术中记录有效的术中出血严重程度评分。单变量分析包括学生T检验,皮尔森的χ2检验,费希尔的精确测试,线性回归,和二元逻辑回归。进行多变量回归以调整基线特征和潜在混杂变量。
结果:共纳入121例患者并纳入分析。在调整了混杂因素后,VIBe评分与术中输血可能性增加相关(β=2.46,P=0.012),术后输血(β=2.36,P=0.015),任何输血(β=2.49,P<.001),总输血量(β=180.8,P=0.020),和估计失血量(EBL)(β=409,P<.001)。验证的术中出血严重程度评分与住院时间无显著关联,重新接纳30天,30天再次手术,30天急诊就诊,术前术后血红蛋白和血细胞比容的变化,总漏极输出,或手术长度。
结论:VIBe量表与胸腰段脊柱手术患者围手术期输血率和EBL相关。总的来说,VIBe量表在脊柱手术中具有临床相关意义,并在临床研究中显示出潜在的效用。
方法:二级。
METHODS: Prospective, single-center study.
OBJECTIVE: To evaluate the clinical relevance of the validated intraoperative bleeding severity scale (VIBe) in thoracolumbar spine surgery.
METHODS: Adult patients aged 18 through 88 undergoing elective decompression, instrumentation, and fusion of the thoracolumbar spine were prospectively enrolled after informed consent was provided and written consent was obtained. Validated intraoperative bleeding severity scores were recorded intraoperatively. Univariate analysis consisted of Student T-tests, Pearson\'s χ2 Tests, Fisher\'s Exact Tests, linear regression, and binary logistic regression. Multivariable regression was conducted to adjust for baseline characteristics and potential confounding variables.
RESULTS: A total of N = 121 patients were enrolled and included in the analysis. After adjusting for confounders, VIBe scores were correlated with an increased likelihood of intraoperative blood transfusion (β = 2.46, P = .012), postoperative blood transfusion (β = 2.36, P = .015), any transfusion (β = 2.49, P < .001), total transfusion volume (β = 180.8, P = .020), and estimated blood loss (EBL) (β = 409, P < .001). Validated intraoperative bleeding severity scores had no significant association with length of hospital stay, 30-day readmission, 30-day reoperation, 30-day emergency department visit, change in pre- to post-op hemoglobin and hematocrit, total drain output, or length of surgery.
CONCLUSIONS: The VIBe scale is associated with perioperative transfusion rates and EBL in patients undergoing thoracolumbar spine surgery. Overall, the VIBe scale has clinically relevant meaning in spine surgery, and shows potential utility in clinical research.
METHODS: Level II.