■探讨不同区域眼底周边屈光不正与中、高度近视的关系。
■在本病例对照研究中,招募了320名6至18岁的儿童和青少年。使用多光谱视网膜屈光形貌(MRT)测量周边屈光不正。球面当量(SE)和圆柱误差分为低,中度,和基于震级范围的高类别。采用Logistic回归检验与近视相关的因素。
■本研究包括152名低度近视参与者和168名中度和高度近视参与者。中度和高度近视的参与者最有可能年龄较大,具有较大的轴向长度(AL),较低的SE,周末观看电子设备的时间减少,中央屈光不正和视网膜上侧中央屈光不正(RDV-S)之间的差异更大,但中央屈光不正和视网膜下侧中央屈光不正(RDV-I)的差异小于低度近视者(均P<0.05)。经过逻辑分析,女性(优势比[OR]=4.14;95%置信区间[CI]=2.16-7.97,P<0.001),AL(OR=6.88,95%CI=4.33~10.93,P<0.001),RDV-I(OR=0.52,95%CI=0.32~0.86,P=0.010)是中高度近视的独立影响因素。
■我们的研究表明,眼睛的视网膜周边屈光(RDV-I)与中度和高度近视有关,RDV-S仅与高度近视相关。
UNASSIGNED: To investigate the association between the peripheral refractive errors of the fundus in different regions and moderate and high myopia.
UNASSIGNED: In this case-control study, 320 children and adolescents aged 6 to 18 years were recruited. Peripheral refractive errors were measured using multispectral retinal refractive topography (MRT). Spherical equivalent (SE) and cylinder errors were classified into low, moderate, and high categories based on the magnitude range. Logistic regression was performed to test the factors associated with myopia.
UNASSIGNED: There were 152 participants with low myopia and 168 participants with moderate and high myopia included in the current study. Participants with moderate and high myopia were most likely to be older, with larger axial length (AL), lower SE, less time to watch electronic devices on the weekend, a higher difference between central refractive error and paracentral refractive error from the superior side of the retina (RDV-S), but a smaller difference between the central refractive error and paracentral refractive error from the inferior side of the retina (RDV-I) than those with low myopia (all P <0.05). After logistic analysis, female sex (odds ratio [OR] = 4.14; 95% confidence interval [CI] = 2.16-7.97, P <0.001), AL (OR = 6.88, 95% CI = 4.33-10.93, P <0.001), and RDV-I (OR = 0.52, 95% CI = 0.32-0.86, P = 0.010) were independent factors for moderate and high myopia.
UNASSIGNED: Our study demonstrated that the retina peripheral refraction of the eyes (RDV-I) was associated with moderate and high myopia, and RDV-S was only associated with high myopia.