■通过使用半峰全宽(FWHM)和智能图像识别测量视网膜血管来研究视网膜血管变化与ICA狭窄之间的相关性。
■本研究选取2018年1月至2020年12月衢州市人民医院血管外科收治的患者,为颈动脉支架术(CAS)做准备。参与者分为两组:无ICA狭窄(第0组)和有ICA狭窄(第1组)。共纳入109例病例,1组50例,0组59例。通过谱域光学相干断层扫描(SD-OCT)获得视网膜上颞区B的血管图像。通过FWHM识别视网膜血管的边缘。用FWHM测量所有受试者的每个血管三次,取平均值,得到视网膜小动脉腔直径(RALD),视网膜小动脉外径(RAOD),视网膜静脉腔直径(RVLD),和视网膜静脉外径(RVOD),动脉壁厚(AWT),静脉壁厚(VWT)=(RVOD-RVLD)/2,动静脉比(AVR)=RAOD/RVOD。
■我们发现,与第0组相比,第1组的RALD(P<0.001)和RAOD(P<0.001)较小,和更宽的RVOD(P<0.001),VWT较厚(P<0.001)。与第1组的对侧眼相比,同侧眼表现出更小的RALD,RAOD和AVR(P<0.001,P<0.001,P<0.001)。在CAS之后,RALD,第1组的RAOD和AVR增加(P<0.001,P<0.001,P<0.001),而RVLD和RVOD降低(P<0.05,P<0.001)。我们的研究揭示了视网膜血管变化与内部ICA狭窄之间的显着相关性。
■将SD-OCT与FWHM结合使用,我们实现了非侵入性,智能,稳定,以及对视网膜血管相关数据的精确采集。这些发现强调了视网膜血管结构改变与ICA狭窄的存在之间的显著相关性。正如我们的研究所证明的那样。
UNASSIGNED: To investigate the correlation between retinal vascular changes and ICA stenosis by measuring retinal vessels using full-width-at-half-maximum (FWHM) and intelligent image recognition.
UNASSIGNED: This research selected patients who were admitted to the Vascular Surgery Department of Quzhou People\'s Hospital from January 2018 to December 2020 and were preparing for Carotid Artery Stenting (CAS). Participants were divided into two groups: without ICA stenosis (Group 0) and with ICA stenosis (Group 1). A total of 109 cases were included in the study, with 50 cases in Group 1 and 59 cases in Group 0. Vascular images of superior temporal zone B of the retina were obtained by spectral domain optical coherence tomography (SD-OCT). The edges of retinal vessels were identified by FWHM. Each vessel of all subjects was measured three times with the FWHM, and the average value was taken to obtain the retinal arteriolar lumen diameter (RALD), retinal arteriolar outer diameter (RAOD), retinal venular lumen diameter (RVLD), and retinal venular outer diameter (RVOD),Arterial Wall Thickness (AWT),Venular Wall Thickness (VWT)=(RVOD-RVLD)/2,Arteriovenous Ratio (AVR) = RAOD/RVOD.
UNASSIGNED: We found that compared to Group 0, Group 1 had smaller RALD (P < 0.001) and RAOD (P < 0.001), and wider RVOD (P < 0.001), with thicker VWT (P < 0.001). When compared with the contralateral eye in Group 1, the ipsilateral eye exhibited even smaller RALD,RAOD and AVR (P < 0.001, P < 0.001, P < 0.001). After CAS, the RALD,RAOD and AVR in Group 1 increased (P < 0.001, P < 0.001, P < 0.001),while the RVLD and RVOD decreased (P < 0.05, P < 0.001). Our research reveals a significant correlation between retinal vascular changes and internal ICA stenosis.
UNASSIGNED: Utilizing SD-OCT in conjunction with the FWHM,we achieved a non-invasive, intelligent, stable, and precise acquisition of data pertaining to retinal vessels. These findings underscore a significant correlation between alterations in retinal vascular structure and the presence of ICA stenosis, as demonstrated by our research.