背景:球囊肺瓣膜成形术(BPV)是一种用于肺狭窄(PS)治疗的程序。在这项研究中,通过2D-斑点追踪超声心动图(2D-STE)测定右心室(RV)表现.
方法:该研究包括25名诊断为PS的BPV儿童和25名正常儿童。使用2D-STE和线性混合模型(LMM)方法进行检查,以确定肺动脉瓣峰值梯度(PVPG)的变化,三尖瓣环形平面收缩压偏移(TAPSE),RV的应变和应变率(SR),左心室射血分数(LVEF)。
结果:两组在TAPSE方面存在显著差异(P=0.001),全局菌株(P=0.001),根尖间隔应变(P=0.024),中隔应变(P=0.001),基底间隔应变(P=0.001),顶侧SR(P=0.001),中外侧SR(P=0.007),基底外侧SR(P=0.001),和心尖间隔SR(P=0.001)。后BPV,LVEF(P=0.001)和TAPSE(P=0.001)升高,而PVPG降低(P=0.001)。在BPV之后,根尖侧向应变增加(P=0.004),中隔应变(P=0.001),根尖间隔应变(P=0.003),中隔应变(P=0.001),基底间隔应变(P=0.048),根尖间隔SR(P=0.025),中隔SR(P=0.023)。性别与基底侧向应变的平均变化显著相关(P=0.019)。中隔应变(P=0.037),中隔SR(P=0.020)。PS儿童的年龄与基底间隔应变(P=0.031)和基底间隔SR(P=0.018)的平均变化有关。
结论:RV中的应变和SR改善了PS患儿的BPV后。儿童的性别和年龄对BPV后RV菌株和SR的变化具有显着影响。
BACKGROUND: Balloon Pulmonary Valvuloplasty (BPV) is a procedure for Pulmonary Stenosis (PS) treatment. In this study, right ventricle (RV) performance was determined through 2D-Speckle Tracking Echocardiography (2D-STE).
METHODS: The study involved 25 diagnosed children with PS undergoing BPV and 25 normal children. They were examined using 2D-STE and Linear Mixed Model (LMM) approach was used to determine changes in Pulmonary Valve Peak Gradient (PVPG), Tricuspid Annular Plane Systolic Excursion (TAPSE), strain and Strain Rate (SR) for RV, and Ejection Fraction for Left Ventricle (LVEF).
RESULTS: Notable differences were found between two groups in TAPSE (P=0.001), global strain (P=0.001), apical septal strain (P=0.024), middle septal strain (P=0.001), basal septal strain (P=0.001), apical lateral SR (P=0.001), middle lateral SR (P=0.007), basal lateral SR (P=0.001), and apical septal SR (P=0.001). Post-BPV, there was an increase in LVEF (P=0.001) and TAPSE (P=0.001) but PVPG decreased (P=0.001). Following BPV, an increase was observed in apical lateral strain (P=0.004), middle septal strain (P=0.001), apical septal strain (P=0.003), middle septal strain (P=0.001), basal septal strain (P=0.048), apical septal SR (P=0.025), and middle septal SR (P=0.023). Gender was remarkably correlated with mean changes in basal lateral strain (P=0.019), middle septal strain (P=0.037), and middle septal SR (P=0.020). Age of PS children was related to mean change in basal septal strain (P=0.031) and basal septal SR (P=0.018).
CONCLUSIONS: Strain and SR in RV improved post-BPV in children with PS. The gender and age of the children revealed remarkable effects on RV strain and SR changes after BPV.