Specific Language Disorder

特定语言障碍
  • 文章类型: Journal Article
    背景:及时检测神经发育和神经系统疾病对于早期干预至关重要。儿童的特定语言障碍(SLI)和帕金森氏病(PD)表现为言语障碍,可用于使用记录的语音信号进行诊断筛查。我们的动机是开发一个准确但计算轻量级的模型,用于基于语音的SLI和PD检测,采用新颖的特征工程技术来模仿深度学习架构的自适应动态权重分配网络能力。
    方法:在这项研究中,我们引入了一种先进的特征工程模型,其中包含一种新颖的特征提取功能,因子晶格模式(FLP),这是一种量子启发的方法,使用类似叠加的机制,让它在自然界中充满活力。FLP包含八个不同的模式,根据数据结构识别最合适的模式。通过FLP的实施,我们自动提取信号特定的纹理特征。此外,我们开发了一种新的特征工程模型来评估FLP的疗效.这个模型是自组织的,产生九个潜在的结果,然后选择最佳的一个。我们的语音分类框架包括:(1)使用所提出的FLP和统计特征提取器进行特征提取;(2)采用迭代邻域分量分析和基于交集的特征选择器进行特征选择;(3)通过支持向量机和k最近邻进行分类;(4)使用组合多数投票来选择最有利的结果来确定结果。
    结果:为了验证我们提出的特征工程模型的分类能力,设计用于自动检测PD和SLI,我们使用了三个PD和SLI患者的语音数据集。我们提出的以FLP为中心的模型对所有PD和SLI数据集实现了95%以上和99.79%以上的分类精度,分别。
    结论:我们的结果表明,所提出的模型是使用语音信号对神经系统状况进行分类的深度学习模型的准确替代方法。
    BACKGROUND: Timely detection of neurodevelopmental and neurological conditions is crucial for early intervention. Specific Language Impairment (SLI) in children and Parkinson\'s disease (PD) manifests in speech disturbances that may be exploited for diagnostic screening using recorded speech signals. We were motivated to develop an accurate yet computationally lightweight model for speech-based detection of SLI and PD, employing novel feature engineering techniques to mimic the adaptable dynamic weight assignment network capability of deep learning architectures.
    METHODS: In this research, we have introduced an advanced feature engineering model incorporating a novel feature extraction function, the Factor Lattice Pattern (FLP), which is a quantum-inspired method and uses a superposition-like mechanism, making it dynamic in nature. The FLP encompasses eight distinct patterns, from which the most appropriate pattern was discerned based on the data structure. Through the implementation of the FLP, we automatically extracted signal-specific textural features. Additionally, we developed a new feature engineering model to assess the efficacy of the FLP. This model is self-organizing, producing nine potential results and subsequently choosing the optimal one. Our speech classification framework consists of (1) feature extraction using the proposed FLP and a statistical feature extractor; (2) feature selection employing iterative neighborhood component analysis and an intersection-based feature selector; (3) classification via support vector machine and k-nearest neighbors; and (4) outcome determination using combinational majority voting to select the most favorable results.
    RESULTS: To validate the classification capabilities of our proposed feature engineering model, designed to automatically detect PD and SLI, we employed three speech datasets of PD and SLI patients. Our presented FLP-centric model achieved classification accuracy of more than 95% and 99.79% for all PD and SLI datasets, respectively.
    CONCLUSIONS: Our results indicate that the proposed model is an accurate alternative to deep learning models in classifying neurological conditions using speech signals.
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  • 文章类型: Journal Article
    目的:患有特定语言障碍(SLI)的儿童可能会出现语音障碍(SSD)和语音意识(PA)缺陷,这使他们面临潜在的阅读问题的风险。这项工作旨在组织阿拉伯语的语音训练干预计划,并评估SLI和SSD儿童的PA训练与语音治疗(PT)的效果。
    方法:这项研究是对60名患有SLI和SSD合并症的儿童进行的,5-7岁。将儿童平均分为两组;每组接受语言治疗结合(PT或PA训练)。语言发展的措施,语音输出,所有患儿均在治疗前和治疗后4个月服用PA.
    结果:两个治疗组在语言和语音产生的发展方面取得了几乎相同的进步,语言年龄和辅音正确(PCC)的百分比没有显着差异。与同时接受PT的儿童相比,PA训练组在PA技能方面的进步更大。
    结论:PA训练可以通过针对儿童对音素的认识和改善声音模式的产生来促进语音技能的发展。
    OBJECTIVE: Children with specific language impairment (SLI) might present with speech sound disorder (SSD) and phonological awareness (PA) deficits which put them at risk of potential reading problems. This work aimed to organize an intervention program in Arabic for phonological training and to assess the effect of PA training versus the phonological therapy (PT) for children with SLI and SSD.
    METHODS: The study was carried out on 60 children with comorbid SLI and SSD, aged 5-7 years. Children were equally divided into two groups; each group received language therapy combined with (PT or PA training). Measures of language development, phonological output, and PA were taken before therapy and at 4 month post-therapy for all children.
    RESULTS: The two therapy groups made nearly the same amount of progress in the development of language and phonological production, with no significant differences regarding language age and percent of consonants correct (PCC). The PA training group progressed more on the PA skills than children who received PT over the same time.
    CONCLUSIONS: PA training could facilitate the development of phonological skills by targeting the child\'s awareness of phonemes and improving the production of sound patterns.
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  • 文章类型: Journal Article
    目的:这项研究调查了特定语言障碍(SLI)儿童的脑电图α节律谱功率,并将其与典型发育儿童进行比较,以更好地了解该疾病的电生理特征。具体来说,我们探索了静息状态脑电图,因为有研究指出它与言语和语言发展有关。
    方法:30名被诊断患有特定语言障碍的儿童和30名典型发育儿童的脑电图记录,年龄4.0-6.11岁,在闭眼和睁眼的条件下进行。计算了与大脑形貌和实验条件有关的α节律谱功率差异。
    结果:在闭眼状态下,在左侧颞部(T5)和枕部电极(O1,O2)中具有特定语言障碍的儿童的α节律谱功率在统计学上显着低于典型发育中的儿童。在眼睛睁开的情况下,患有SLI的儿童在左颞叶(T3,T5)显示出显著较低的α节律谱功率,顶叶(P3,Pz),和枕骨电极(O1,O2)。关于条件之间的α节律谱功率的相对变化(闭眼条件期间的平均α节律谱功率与睁眼条件期间的平均α节律谱功率之间的差异除以闭眼条件期间的平均α节律谱功率),组间没有统计学上的显著差异。
    结论:左颞叶α节律谱功率较低,左,顶叶中线,枕叶脑区可能是SLI患儿有价值的电生理标志物。需要进一步研究以检查SLI患者的EEGα谱功率与一般处理和记忆缺陷之间的联系。
    This study investigated EEG alpha rhythm spectral power in children with Specific Language Impairment (SLI) and compared it to typically developing children to better understand the electrophysiological characteristics of this disorder. Specifically, we explored resting-state EEG, because there are studies that point to it being linked to speech and language development.
    EEG recordings of 30 children diagnosed with specific language impairment and 30 typically developing children, aged 4.0-6.11 years, were carried out under eyes closed and eyes open conditions. Differences in alpha rhythm spectral power in relation to brain topography and experimental conditions were calculated.
    In the eyes closed condition, alpha rhythm spectral power was statistically significantly lower in children with specific language impairment in the left temporal (T5) and occipital electrodes (O1, O2) than in typically developing children. In the eyes open condition, children with SLI showed significantly lower alpha rhythm spectral power in the left temporal (T3, T5), parietal (P3, Pz), and occipital electrodes (O1, O2). There were no statistically significant differences between the groups in relation to the relative change (the difference between average alpha rhythm spectral power during eyes closed condition and average alpha rhythm spectral power during eyes open condition divided by average alpha rhythm spectral power during eyes closed condition) in the alpha rhythm spectral power between the conditions.
    Lower alpha rhythm spectral power in the left temporal, left, midline parietal, and occipital brain regions could be a valuable electrophysiological marker in children with SLI. Further investigation is needed to examine the connection between EEG alpha spectral power and general processing and memory deficits in patients with SLI.
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  • 文章类型: Journal Article
    目的:识别患有特定语言障碍(SLI)的儿童可能很困难,即使他们的语言在整个童年时期都落后于同龄同龄人。在简单从句中以时态标记为特征的临床语法标记对于幼儿是有效且可靠的,但受到8岁左右的天花板效应的限制。这项研究评估了一个新的,在纵向数据中受SLI影响或不受影响的儿童中,在语法上更具挑战性的复杂句子任务,年龄5-18岁。
    方法:4183名儿童(213名未受影响,270名5至18岁之间的受影响)参加,在滚动招聘纵向设计之后,总共进行了4148次观察。新的实验性语法判断任务遵循句法位点的语言概念,以确定复杂从句中的局限性和移动。生长建模方法评估了四种不同结果随时间的群体差异;假设三个是为了评估授权句子位点中公开的有限形式的可选遗漏,一个人评估了紧张标记的明显错误。
    结果:与早期对年幼儿童的研究一样,SLI组的生长模型始终低于未受影响的组,尽管各组的生长轨迹没有差异。结果在四个项目类型中复制,这些项目类型由遗漏定义,对于带有明显的时态标记错误的项目,差异很小。儿童非语言智商的协变量,母亲的教育,儿童性并没有显著缓解这些影响.
    结论:结果支持这项任务,因为它对SLI儿童的识别具有潜在的筛查价值,并且与任务需求的语言解释一致。
    Identification of children with specific language impairment (SLI) can be difficult even though their language can lag that of age peers throughout childhood. A clinical grammar marker featuring tense marking in simple clauses is valid and reliable for young children but is limited by ceiling effects around the age of 8 years. This study evaluated a new, more grammatically challenging complex sentence task in children affected or unaffected with SLI in longitudinal data, ages 5-18 years.
    Four hundred eighty-three children (213 unaffected, 270 affected) between 5 and 18 years of age participated, following a rolling recruitment longitudinal design encompassing a total of 4,148 observations. The new experimental grammaticality judgment task followed linguistic concepts of syntactic sites for finiteness and movement within complex clauses. Growth modeling methods evaluated group differences over time for four different outcomes; three were hypothesized to evaluate optional omissions of overt finiteness forms in authorized sentence sites, and one evaluated an overt error of tense marking.
    As in earlier studies of younger children, growth models for the SLI group were consistently lower than the unaffected group, although the growth trajectories across groups did not differ. The results replicated across four item types defined by omissions with minor differences for an item with an overt error of tense marking. Covariates of child nonverbal IQ, mother\'s education, and child sex did not significantly moderate these effects.
    The outcomes support the task as having potential screening value for identification of children with SLI and are consistent with linguistic interpretations of task demands.
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  • 文章类型: Journal Article
    使用状态级别的数据,我们报告了2009年至2019年田纳西州3至8年级学生的特殊教育(SPED)趋势的未调整和调整的优势比,分为三个语言组:以英语为母语的人(NES),精通英语的双语者(EPB),和当前英语学习者(当前EL)。我们报告了所有SPED残疾类别和五个普遍残疾类别的趋势(具体的学习残疾,特定的语言障碍,智力残疾,其他健康损害,和自闭症)。横截面分析样本包括来自28个地区的812,783名学生,这些学生符合该州设定的SPED风险比阈值。结果显示,与NES学生相比,EPB和当前EL学生普遍不太可能接受SPED服务,这表明SPED代表中语言地位差异的证据。此外,结果取决于是否进行了调整以产生赔率比,特别是对于发病率较高的残疾(特定的学习障碍,特定的语言障碍,和智力残疾)。最后,代表性不足的最严重证据是发病率较低的残疾(其他健康损害和自闭症).我们的结果强调,有必要进一步检查母语不是英语(EPB和CurrentEL)的学习者的SPED识别率较低。我们讨论语境化研究,实践,以及我们发现的政策含义。
    Using U.S. state-level data, we report unadjusted and adjusted odds ratio of special education (SPED) trends in Tennessee from 2009 to 2019 for students in Grades 3 to 8 by three language groups: native English speakers (NES), English-proficient bilinguals (EPB), and Current English learners (Current EL). We report trends across all SPED disability categories and across five prevalent disability categories (specific learning disability, specific language impairment, intellectual disability, other health impairments, and autism). The cross-sectional analytic sample included 812,783 students from 28 districts that met the SPED risk ratio threshold set by the state. Results revealed that, compared with NES students, both EPB and Current EL students were generally less likely to receive SPED services, suggesting evidence of language status disparities in SPED representation. Furthermore, findings varied depending on whether adjustments were made to generate odds ratios, especially for higher-incidence disabilities (specific learning disability, specific language impairment, and intellectual disability). Finally, the most severe evidence of underrepresentation was in lower-incidence disabilities (other health impairments and autism). Our results underscore the need for further examination into low rates of SPED identification among learners whose first language is not English (EPB and Current EL). We discuss the contextualized research, practice, and policy implications of our findings.
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  • 文章类型: Observational Study
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  • 文章类型: Journal Article
    本文调查了15名疑似特定语言障碍(SLI)的普通话儿童(年龄在4岁之间;5至6岁;0)和29名典型发展(TD)对照的相对条款(RC)的理解。字符图片匹配任务的结果表明(i)在SLI儿童中,主题RC比对象RC更好地理解,但是TD儿童对两种RC的理解没有不对称;(ii)SLI儿童的表现明显差于TD同龄人;(iii)SLI儿童容易犯主题角色反转错误和中间错误。为了克服以往账户的缺点,因此,我们提出了边缘特征规范下假说,这不仅可以解释SLI儿童的理解不对称性,而且还可以阐明他们在任务中犯下的错误的性质。
    This paper investigates the comprehension of Relative Clauses (RCs) in 15 Mandarin children with suspected Specific Language Impairment (SLI) (aged between 4; 5 and 6; 0) and 29 typically developing (TD) controls. Results from a Character Picture Matching Task indicate that (i) the subject RC was better understood than the object RC in children with SLI, but there was no asymmetry in the comprehension of the two RCs in TD children; (ii) the performance of children with SLI was significantly worse than that of their TD peers; (iii) children with SLI were prone to committing thematic role reversal errors and middle errors. In order to overcome the shortcomings of previous accounts, we therefore put forward the Edge Feature Underspecification Hypothesis, which can not only explain the asymmetry of comprehension seen in children with SLI but also shed light on the nature of errors committed by them in the task.
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  • 文章类型: Observational Study
    诊断为言语和语言障碍(SLI)的儿童的听觉处理是非典型的,与典型发育(TD)儿童相比,其特征是大脑激活减少。在典型的言语和语言发展过程中,额叶,temporal,后部区域在单字听音期间参与,而对于非单词听力,这是极不可能的,感知或说话后,没有频繁的神经元激活,足以形成稳定的网络连接。这项研究旨在调查与TD儿童相比,SLI儿童在听单词和非单词时α节律的电生理皮层活动。参与者是50名SLI儿童,4至6岁,以及50名年龄相关的TD儿童。分为2个亚组:第一亚组-4.0至5.0岁的儿童(E=25,C=25)和第二亚组-5.0至6.0岁的儿童(E=25,C=25)。年龄较小的儿童组在单词或非单词听力方面的α谱功率没有统计学上的显着差异。相比之下,对于单词和非单词听力,差异存在于前额叶,temporal,和双侧顶枕区。与TD儿童相比,SLI儿童在单词和非单词听力方面表现出一定的α不同步。由于单词刺激的未知存在,非单词感知会引起更多的大脑区域。缺乏足够的alpha去同步与SLI儿童在行为水平上的词汇和语音处理中存在的困难是一致的。
    Auditory processing in children diagnosed with speech and language impairment (SLI) is atypical and characterized by reduced brain activation compared to typically developing (TD) children. In typical speech and language development processes, frontal, temporal, and posterior regions are engaged during single-word listening, while for non-word listening, it is highly unlikely that perceiving or speaking them is not followed by frequent neurones\' activation enough to form stable network connections. This study aimed to investigate the electrophysiological cortical activity of alpha rhythm while listening words and non-words in children with SLI compared to TD children. The participants were 50 children with SLI, aged 4 to 6, and 50 age-related TD children. Groups were divided into 2 subgroups: first subgroup - children aged 4.0 to 5.0 years old (E = 25, C = 25) and second subgroup - children aged 5.0 to 6.0 years old (E = 25, C = 25). The younger children\'s group did not show statistically significant differences in alpha spectral power in word or non-word listening. In contrast, in the older age group for word and non-word listening, differences were present in the prefrontal, temporal, and parieto-occipital regions bilaterally. Children with SLI showed a certain lack of alpha desynchronization in word and non-word listening compared with TD children. Non-word perception arouses more brain regions because of the unknown presence of the word stimuli. The lack of adequate alpha desynchronization is consistent with established difficulties in lexical and phonological processing at the behavioral level in children with SLI.
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  • 文章类型: Journal Article
    遭受逆境的儿童(例如,长期贫困,创伤性事件,和虐待)在规范参考语言评估中表现低于年龄预期的风险增加,但尚不清楚特定语言障碍(SLI)的风险是否更高.这项探索性研究调查了逆境暴露是否与语法知识和SLI减少有关。
    对30名已知有逆境暴露史的学龄儿童进行了语言变异诊断评估-规范参考(DELV-NR)评估的语法子测试。他们的主要照顾者还完成了一项全面的逆境暴露措施,捕获了不良事件类型,频率,慢性,和严重性。分析包括t检验,相关性,Mann-WhitneyU测试,和卡方。
    总的来说,样本在DELV-NR语法子检验中表现低于年龄预期,符合SLI诊断标准的参与者比例(20%)高于预期.SLI和典型语言(TL)组的逆境剂量没有显着差异,频率,慢性,或严重程度;然而,SLI组参与者遭受身体创伤的可能性是TL组参与者的1.46倍.
    根据DELV-NR规范样本,已知逆境暴露历史的儿童比预期的更频繁地出现语法缺陷和SLI;然而,不良事件的特征与SLI状态无关,除了暴露于身体创伤(例如,身体虐待和受害)。需要进一步的研究来调查该人群中SLI的患病率和潜在的因果途径。
    https://doi.org/10.23641/asha.20483706。
    Children exposed to adversity (e.g., chronic poverty, traumatic events, and maltreatment) are at increased risk for performing below age expectations on norm-referenced language assessments, but it is unknown whether the risk is higher for specific language impairment (SLI). This exploratory study investigated whether adversity exposure is associated with reduced grammar knowledge and SLI.
    The syntax subtest of the Diagnostic Evaluation of Language Variation-Norm-Referenced (DELV-NR) assessment was administered to 30 school-age children with known histories of adversity exposure. Their primary caregiver also completed a comprehensive adversity exposure measure, which captured adverse event type, frequency, chronicity, and severity. Analyses included t tests, correlations, Mann-Whitney U tests, and chi-square.
    Overall, the sample performed below age expectations on the DELV-NR Syntax subtest, and a higher percentage of participants (20%) met diagnostic criteria for SLI than expected. The SLI and typical language (TL) groups did not significantly differ in adversity dosage, frequency, chronicity, or severity; however, participants in the SLI group were 1.46 times more likely to have experienced physical trauma than the participants in the TL group.
    Children with known histories of adversity exposure presented with grammatical deficits and SLI more often than expected based on the DELV-NR normative sample; however, features of the adverse event did not associate with SLI status except for exposure to physical trauma (e.g., physical abuse and victimization). Future research is needed to investigate the prevalence and potential causal pathways of SLI in this population.
    https://doi.org/10.23641/asha.20483706.
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  • 文章类型: Journal Article
    已提出程序记忆中的缺陷来解释特定语言障碍(SLI)中的语言缺陷。SLI的程序缺陷假说(PDH)说明的一个关键方面是,陈述性记忆是完整的,并且在SLI个体的语言习得中起着补偿机制的作用。当前的研究检查了一组患有SLI的青少年中这些预测的词汇-语音和词汇-语义处理的神经相关性,这些青少年患有程序性记忆障碍和一组按时间顺序年龄匹配的(CA)正常对照。
    参与者完成了旨在测量程序和陈述性记忆的任务,以及旨在评估听觉模态中的词汇语义和词汇语音处理的两个ERP任务。使用统计学习任务评估程序记忆。使用调节语义一致性的句子判断任务评估词汇语义处理,并使用调节词频的单词/非单词决策任务评估词汇语音处理。任务的行为表现,皮层反应的平均振幅,并检查了动画地形图。
    对于患有SLI的青少年来说,统计单词学习任务的表现是偶然的,而声明性记忆与CA对照没有什么不同。具有SLI和CA对照的青少年在词汇语义任务上的行为准确性相同,但与CA对照相比,具有SLI的青少年在词汇语音任务上的准确性明显较差。响应于两组的词汇语义任务的语义一致性,得出了N400组件,但在SLI和CA组的皮层反应的位置和时间过程中均存在差异。对于CA控件,而不是SLI的青少年,通过词频在词汇语音任务中得出N400分量。相比之下,事后分析显示,SLI青少年的皮质反应基于可成像性,但不是CA控制。对于CA对照组,统计单词学习与词汇决策任务的处理速度显着相关,而对于SLI的青少年则不相关。相比之下,统计单词学习能力与N400在任何一组任务上的调制均不相关。
    行为数据表明完整的语义概念知识,但是SLI青少年的词汇语音处理受损,与PDH一致。响应语义一致性和单词频率的皮层激活模式表明,然而,具有SLI病史的青少年对词汇语义和词汇语音信息的处理可能会得到与CA对照的重叠和不重叠神经发生器的支持,以及对陈述性记忆策略的更大依赖。一起来看,这项研究的结果表明,具有SLI历史的青少年的词汇中单词的基本表示形式可能与典型的同龄人在质量上有所不同,但是这些差异可能只有当行为数据和神经皮层激活模式一起检查时才会明显。
    Deficits in procedural memory have been proposed to account for the language deficits in specific language impairment (SLI). A key aspect of the procedural deficit hypothesis (PDH) account of SLI is that declarative memory is intact and functions as a compensatory mechanism in the acquisition of language in individuals with SLI. The current study examined the neural correlates of lexical-phonological and lexical-semantic processing with respect to these predictions in a group of adolescents with SLI with procedural memory impairment and a group of chronologically age-matched (CA) normal controls.
    Participants completed tasks designed to measure procedural and declarative memory and two ERP tasks designed to assess lexical-semantic and lexical-phonological processing in the auditory modality. Procedural memory was assessed using a statistical learning task. Lexical-semantic processing was assessed using a sentence judgment task modulating semantic congruency and lexical-phonological processing was assessed using a word/nonword decision task modulating word frequency. Behavioral performance on the tasks, mean amplitude of the cortical response, and animated topographs were examined.
    Performance on the statistical word-learning task was at chance for the adolescents with SLI, whereas declarative memory was no different from the CA controls. Behavioral accuracy on the lexical-semantic task was the same for the adolescents with SLI and CA controls but accuracy on the lexical-phonological task was significantly poorer for the adolescents with SLI as compared to the CA controls. An N400 component was elicited in response to semantic congruency on the lexical-semantic task for both groups but differences were noted in both the location and time course of the cortical response for the SLI and CA groups. An N400 component was elicited by word frequency on the lexical-phonological task for the CA controls not for the adolescents with SLI. In contrast, post hoc analysis revealed a cortical response based on imageability for the adolescents with SLI, but not CA controls. Statistical word learning was significantly correlated with speed of processing on the lexical decision task for the CA controls but not for the adolescents with SLI. In contrast, statistical word learning ability was not correlated with the modulation of the N400 on either task for either group.
    The behavioral data suggests intact semantic conceptual knowledge, but impaired lexical phonological processing for the adolescents with SLI, consistent with the PDH. The pattern of cortical activation in response to semantic congruency and word frequency suggests, however, that the processing of lexical-semantic and lexical-phonological information by adolescents with a history of SLI may be supported by both overlapping and nonoverlapping neural generators to those of CA controls, and a greater reliance on declarative memory strategies. Taken together, the findings from this study suggest that the underlying representations of words in the lexicons of adolescents with a history of SLI may differ qualitatively from those of their typical peers, but these differences may only be evident when behavioral data and neural cortical patterns of activation are examined together.
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