Spatial variation

空间变异
  • 文章类型: Journal Article
    背景:互联网是检索相关信息的首选健康信息来源。在埃塞俄比亚,互联网普及率逐年提高,但与世界其他地区和邻近的非洲国家相比,它仍然处于较低水平。由于缺乏足够的信息,评估互联网使用情况很重要,空间变异,以及埃塞俄比亚育龄妇女使用互联网的决定因素。
    方法:使用2016年EDHS的次要数据对15,683名15-49岁女性进行分析。使用ArcGIS10.7进行空间分析。利用SaTScan10.1.2软件应用Kuldorff方法,利用Bernoulli模型对互联网使用的纯空间聚类进行分析。采用多水平混合效应逻辑回归估计社区方差,以识别与互联网使用相关的个人和社区水平因素。所有型号都安装在STATA17.0版本中,最后,报告了校正比值比(AOR)和相应的95%置信区间(CI).
    结果:互联网使用的幅度为4.97%±95%CI(4.63-5.32)。女性总体平均年龄为24.21±8.06岁,年龄范围15-24岁构成较大的群体(39.2%)。中等及以上文化程度的女性[AOR=6.47;95%CI(5.04,8.31)],未婚[AOR=2.60;95%CI(1.89,3.56)],富[AOR=1.95;95%CI(1.00,3.80)],拥有手机[AOR=3.74;95%CI(2.75,5.09)],媒体暴露[AOR=2.63;95%CI(2.03,3.42)],和城市[AOR=1.80;95%CI(1.08,3.01)]使用互联网的几率更高。发现互联网使用的空间变化是非随机的(全局Moran'sI=0.58,p值<0.001)。确定了位于亚的斯亚贝巴市的57个主要集群,相对可能性为10.24,对数似然比为425.16。
    结论:埃塞俄比亚育龄妇女的互联网使用率为4.97,在全国范围内具有显著的空间差异。社区和个人层面的因素都会影响埃塞俄比亚的互联网使用。因此,教育妇女,改善对媒体的访问,鼓励妇女实行计划生育,支持家庭财富可以改善女性的互联网使用。
    BACKGROUND: The Internet is the preferred source of health information for retrieving relevant information. In Ethiopia, the Internet penetration rate is improving year to year, but it is still at a low level compared to the rest of the world and neighboring African countries. Due to a lack of adequate information, it is important to assess Internet use, spatial variation, and determinants of Internet use among reproductive-age group women in Ethiopia.
    METHODS: Secondary data from EDHS 2016 were used to analyze 15,683 women aged 15-49 years. Spatial analysis was performed using ArcGIS 10.7. The Bernoulli model was used by applying Kuldorff\'s methods using SaTScan 10.1.2 software to analyze the purely spatial clusters of Internet use. A multilevel mixed-effect logistic regression was applied to estimate community variance to identify individual- and community-level factors associated with Internet use. All models were fitted in STATA version 17.0, and finally, the adjusted odds ratio (AOR) with a corresponding 95% confidence interval (CI) was reported.
    RESULTS: The magnitude of Internet use was 4.97% ± 95% CI (4.63-5.32). The overall average age of women was 24.21 ± 8.06 years, with the age range 15-24 years constituting the larger group (39.2%). Women with secondary and above education [AOR = 6.47; 95% CI (5.04, 8.31)], unmarried [AOR = 2.60; 95% CI (1.89, 3.56)], rich [AOR = 1.95; 95% CI (1.00, 3.80)], own a mobile phone [AOR = 3.74; 95% CI (2.75, 5.09)], media exposure [AOR = 2.63; 95% CI (2.03, 3.42)], and urban [AOR = 1.80; 95% CI (1.08, 3.01)] had higher odds of Internet use. The spatial variation in Internet use was found to be nonrandom (global Moran\'s I = 0.58, p value < 0.001). Fifty-seven primary clusters were identified that were located in Addis Ababa city with a relative likelihood of 10.24 and a log-likelihood ratio of 425.16.
    CONCLUSIONS: Internet use among reproductive-age women in Ethiopia is 4.97 and has significant spatial variation across the country. Both community- and individual-level factors affect Internet use in Ethiopia. Therefore, educating women, improving access to media, encouraging women to use family planning, and supporting household wealth could improve women\'s Internet use.
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  • 文章类型: Journal Article
    大多数孕产妇死亡与缺乏熟练的接生服务有关。因为分娩是大多数孕产妇死亡的原因,熟练的接生对于降低孕产妇死亡率至关重要。在埃塞俄比亚,熟练接生的使用率很低,确定决定使用熟练接生的因素至关重要。因此,这项研究旨在评估空间分布,与财富相关的不平等,以及埃塞俄比亚熟练助产的决定因素。
    使用2019年迷你EDHS对5,251名育龄女性进行了二次数据分析。集中指数和图形用于评估与财富相关的不平等。进行空间分析以确定空间分布,并使用多水平逻辑回归分析来确定埃塞俄比亚熟练出生的预测因素。分析是使用STATA版本14,ArcGIS,和SaTscan软件。
    熟练分娩的患病率为50.04%(95%CI:48.69%,51.40%)在埃塞俄比亚。老年,结婚了,受过教育,有电视和收音机,ANC访问,多胎,有很大的家庭尺寸,拥有丰富的财富指数,住在农村住宅,生活在高度贫困的社区和妇女的教育水平是熟练接生的重要预测因素。熟练的接生率不成比例地集中在富裕家庭中[C=0.482;95%CI:0.436,0.528]。索马里的非熟练接生率很高,SNNP,Afar,和阿姆哈拉地区的南部地区。索马里和埃塞俄比亚奥罗米亚地区某些地区的非熟练助产的主要集群。
    埃塞俄比亚一半的妇女没有使用具有显著空间聚类的熟练助产士。年龄,婚姻状况,教育状况,ANC访问,有电视和收音机,奇偶校验,家庭大小,财富指数,residence,社区层面的贫困,和社区妇女教育水平是熟练接生的重要预测因素。熟练的接生率在富裕家庭中分布不均。索马里各地区,SNNP,Afar,Amhara南部被确定为使用非熟练接生的患病率很高。公共卫生干预措施应针对那些使用非熟练助产士的高风险妇女。
    UNASSIGNED: The majority of maternal deaths were associated with a lack of access to skilled birth attendance. Because childbirth accounts for most maternal deaths, skilled birth attendance is crucial for reducing maternal mortality. The use of skilled birth attendance in Ethiopia is low, and it is crucial to identify factors that determine the use of skilled birth attendance. Hence, this study aimed to assess the spatial distribution, wealth-related inequality, and determinants for skilled birth attendance in Ethiopia.
    UNASSIGNED: Secondary data analysis was done with a total weighted sample of 5,251 reproductive-aged women using the 2019 mini EDHS. The concentration index and graph were used to assess wealth-related inequalities. Spatial analysis was done to identify the spatial distribution and multilevel logistic regression analysis was used to identify predictors of skilled birth attendance in Ethiopia. Analysis was done using STATA version 14, ArcGIS, and SaTscan software.
    UNASSIGNED: The prevalence of skilled birth attendance was 50.04% (95% CI: 48.69%, 51.40%) in Ethiopia. Old age, being married, being educated, having television and radio, having ANC visits, being multiparous, having large household sizes, having a rich wealth index, living in rural residence, and living in a high level of community poverty and women\'s education were significant predictors of skilled birth attendance. Skilled birth attendance was disproportionately concentrated in rich households [C = 0.482; 95% CI: 0.436, 0.528]. High prevalence of unskilled birth attendance was found in Somalia, SNNP, Afar, and southern parts of the Amhara regions. Primary clusters of unskilled birth attendance Somalia and some parts of Oromia region of Ethiopia.
    UNASSIGNED: Half of the women in Ethiopia did not utilize skilled birth attendants with significant spatial clustering. Age, marital status, educational status, ANC Visit, having television and radio, parity, household size, wealth index, residence, community level poverty, and community level of women\'s education were significant predictors of skilled birth attendance. Skilled birth attendance was unevenly concentrated in rich households. The regions of Somalia, SNNP, Afar, and southern Amhara were identified as having a high prevalence of using unskilled birth attendance. Public health interventions should target those women at high risk of using unskilled birth attendants.
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  • 文章类型: Journal Article
    邻苯二甲酸酯(PAEs),被认为是内分泌干扰物,在使用过程中释放到环境中,从而产生不利的生态影响。这项研究调查了这种情况,来源,从黄河和长江流域36个采样点获得的地表水中PAEs的风险评估。黄河中PAEs的总浓度从124.5到836.5ng/L,主要类型为邻苯二甲酸二甲酯(DMP)(75.4±102.7ng/L)和邻苯二甲酸二异丁酯(DiBP)(263.4±103.1ng/L)。浓度表现出上游(512.9±202.1ng/L)>中游(344.5±135.3ng/L)>下游(177.8±46.7ng/L)的模式。在长江,总浓度范围从81.9到441.6ng/L,DMP(46.1±23.4ng/L),邻苯二甲酸二乙酯(DEP)(93.3±45.2ng/L),以DiBP(174.2±67.6ng/L)为主要成分。浓度水平遵循中游(324.8±107.3ng/L)>上游(200.8±51.8ng/L)>下游(165.8±71.6ng/L)模式。应注意HH上游DiBP的中度生态风险,CJ的上游和中游都需要考虑与邻苯二甲酸二正辛酯(DNOP)相关的中度生态风险。相反,在其他地区,PAEs的相关风险较低或可忽略不计。黄河PAEs的主要来源是建设用地的释放,在长江流域,它源于排放到河流中的湖泊和森林中的污染物的积累。这些发现有助于查明PAEs污染的来源并制定黄河和长江的控制策略,为其他主要河流的全球PAEs研究提供有价值的见解。
    Phthalate esters (PAEs), recognized as endocrine disruptors, are released into the environment during usage, thereby exerting adverse ecological effects. This study investigates the occurrence, sources, and risk assessment of PAEs in surface water obtained from 36 sampling points within the Yellow River and Yangtze River basins. The total concentration of PAEs in the Yellow River spans from 124.5 to 836.5 ng/L, with Dimethyl phthalate (DMP) (75.4 ± 102.7 ng/L) and Diisobutyl phthalate (DiBP) (263.4 ± 103.1 ng/L) emerging as the predominant types. Concentrations exhibit a pattern of upstream (512.9 ± 202.1 ng/L) > midstream (344.5 ± 135.3 ng/L) > downstream (177.8 ± 46.7 ng/L). In the Yangtze River, the total concentration ranges from 81.9 to 441.6 ng/L, with DMP (46.1 ± 23.4 ng/L), Diethyl phthalate (DEP) (93.3 ± 45.2 ng/L), and DiBP (174.2 ± 67.6 ng/L) as the primary components. Concentration levels follow a midstream (324.8 ± 107.3 ng/L) > upstream (200.8 ± 51.8 ng/L) > downstream (165.8 ± 71.6 ng/L) pattern. Attention should be directed towards the moderate ecological risks of DiBP in the upstream of HH, and both the upstream and midstream of CJ need consideration for the moderate ecological risks associated with Di-n-octyl phthalate (DNOP). Conversely, in other regions, the associated risk with PAEs is either low or negligible. The main source of PAEs in Yellow River is attributed to the release of construction land, while in the Yangtze River Basin, it stems from the accumulation of pollutants in lakes and forests discharged into the river. These findings are instrumental for pinpointing sources of PAEs pollution and formulating control strategies in the Yellow and Yangtze Rivers, providing valuable insights for global PAEs research in other major rivers.
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  • 文章类型: Journal Article
    近年来,有机磷阻燃剂(OPFRs)的流行和危害已经引起了全世界的关注。这项研究检查了在中国东部钱塘江的水和沉积物样品中观察到的25个OPFRs,以及它们的发生,空间分布,可能的起源,和生态危害。在水和沉积物样品中检测到所有25个OPFRs。水和沉积物中Σ25OPFRs的水平为35.5-192ng/L和8.84-48.5ng/gdw,分别。氯化OPFRs是水中的主要贡献,而烷基-OPFRs是沉积物中最常见的同源物。空间分析显示,邻近城市的样本位置的OPFRs水浓度更高。减缓水流,使水库成为OPFRs的主要水槽,大坝可以防止OPFRs通过钱塘江移动。正矩阵分解表明聚氯乙烯中的增塑剂,聚酯树脂,聚氨酯泡沫在水中的贡献最大,而聚氨酯泡沫和纺织品是沉积物的主要来源。OPFRs的沉积物-水交换分析表明,沉积物中的12个OPFRs可以重新进入水体。风险商显示生态风险为低至中,但是磷酸三苯酯暴露对水生生物构成了很高的生态风险。
    In recent years, the prevalence and danger of organophosphorus flame retardants (OPFRs) have drawn attention from all around the world. This study examined twenty-five OPFRs observed in water and sediment samples from the Qiantang River in eastern China, as well as their occurrence, spatial distribution, possible origins, and ecological hazards. All the 25 OPFRs were detected in water and sediment samples. The levels of Σ25OPFRs in water and sediment were 35.5-192 ng/L and 8.84-48.5 ng/g dw, respectively. Chlorinated OPFRs were the main contributions in water, whereas alkyl-OPFRs were the most common congeners found in sediment. Spatial analysis revealed that sample locations in neighboring cities had somewhat higher water concentrations of OPFRs. Slowing down the river current and making the reservoir the main sink of OPFRs, the dam can prevent OPFRs from moving via the Qiantang River. Positive matrix factorization indicated that plasticizer in polyvinyl chloride, polyester resins, and polyurethane foam made the greatest contributions in water, whereas polyurethane foam and textile were the predominant source in sediment. Analysis of sediment-water exchange of OPFRs showed that twelve OPFRs in sediments can re-enter into the water body. The risk quotients showed the ecological risk was low to medium, but trixylyl phosphate exposures posed high ecological risk to aquatic organisms.
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  • 文章类型: Journal Article
    有一些证据表明,大西洋鲑鱼的河流迁徙成功,在他们第一次向海迁移时,在空间和时间上都是变化的。然而,我们对推动这种变化的原因知之甚少。在这项研究中,我们使用声学遥测技术来量化大西洋鲑鱼第一次向海迁移时河流迁移成功的时空变化。共有4120条大西洋鲑鱼在苏格兰的22条河流中迁徙,英格兰,爱尔兰,和北爱尔兰多年来被纳入研究。如果发现个人离开河流进入海水,则将其定义为成功的移民。结果表明,迁移成功的显着时间(长达4年)和空间(河流)变化,河流之间的总体迁移成功率从3.4%到97.0%不等,年份从3.4%到61.0%不等。迁移成功的时间变化是特定于河流的,一些河流比其他河流在时间上更稳定(年份之间几乎没有变化)。在所有的河流和岁月中,个体迁移成功由身体状况预测为阳性,由标签负担预测为阴性。人口的迁移成功率(迁移成功标准化为普通河流距离[比例km-1])是由许多环境因素预测的。由湿地和林地组成的河流流域比例积极预测了移民成功,而集水区中草地和泥炭地的比例对迁移成功率有负面影响。尽管在这项研究中没有直接检查这些效应可能起作用的机制,我们讨论了它们可能发生的一些潜在途径。
    There is some evidence that the river migration success of Atlantic salmon smolts, on their first migration to sea, varies both spatially and temporally. However, we have only a poor understanding of what may be driving this variation. In this study, we used acoustic telemetry to quantify the spatial and temporal variations in river migration success in Atlantic salmon smolts on their first migration to sea. In total 4120 Atlantic salmon smolts migrating through 22 rivers in Scotland, England, Ireland, and Northern Ireland over multiple years were included in the study. Individuals were defined as successful migrants if detected leaving the river to enter marine waters. The results show significant temporal (up to 4 years) and spatial (river) variations in migration success, with overall between-river migration success varying from 3.4% to 97.0% and between years from 3.4% and 61.0%. Temporal variation in migration success was river specific, with some rivers being more temporally stable (exhibiting little variation between years) than others. Across all rivers and years, individual migration success was predicted positively by body condition and negatively by tag burden. The rate of migration success for a population (migration success standardized to a common river distance [proportion km-1]) was predicted by a number of environmental factors. The proportion of river catchment that comprised wetland and woodland positively predicted migration success, whereas the proportion of grassland and peatland in a catchment negatively predicted the rate of migration success. Although the mechanisms through which these effects may be operating were not directly examined in this study, we discuss some potential routes through which they may occur.
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  • 文章类型: Journal Article
    在全球范围内,妇女面临着粮食不安全和营养不良的斗争,埃塞俄比亚尤其受到这些问题的影响。为了应对这一挑战,埃塞俄比亚多年来一直实施现金和食品安全网计划。然而,关于程序的因素和空间分布的可用信息有限,没有埃塞俄比亚最近的国家证据。因此,这项研究的目的是调查埃塞俄比亚生产安全网计划(PSNP)的空间聚类和决定因素。
    这项研究利用了埃塞俄比亚人口与健康调查的数据。样本包括8,570个加权家庭。鉴于数据的分层性质,采用多水平logistic回归模型来确定影响结局变量的因素.使用SaTScan软件和Bernoulli模型检查了从PSNP获得帮助的个人的地理集群,还有Kulldorff方法.使用ArcGIS10.8版可视化了计划受益人的全国分布。如果变量的P值<0.05,则认为它们具有统计学意义。
    埃塞俄比亚家庭中PSNP的总体覆盖率为13.54%[95%置信区间(CI):12.84-14.29]。研究表明,来自富裕家庭的人们调整了优势比[AOR=0.46(95%CI:(0.33,0.64))],来自最富有家庭的那些[AOR=0.26(95%CI:(0.17,0.41))],和那些受过良好教育的户主[AOR=0.45(95%CI:(0.28,0.71))]与他们的同行相比,使用PSNP的可能性较低。相反,户主年龄[AOR=1.02(95%CI:(1.01,1.02))]和家庭规模[AOR=1.05(95%CI:1.021.10)]的单位增加显示加入PSNP的可能性更高,分别。加入社区健康保险[AOR=3.21(95%CI:(2.58,4.01))]的户主被纳入PSNP的几率明显高于其同类户主。属于高贫困水平社区[AOR=2.68(95%CI:(1.51,4.79))]和社区健康保险[AOR=2.49(95%CI:(1.51,4.11))]的负责人与他们的同行相比,更倾向于利用PSNP。
    根据收集到的有关PSNP的调查结果,PSNP被判定为实施状态较低。我们发现了年龄等因素,性别,区域,财富,教育,家庭大小,regions,和健康保险具有统计学意义。因此,鼓励妇女赋权,以社区为基础的意识创造,建议与区域国家协调。
    UNASSIGNED: There is a global struggle with food insecurity and undernutrition among women, and Ethiopia has been particularly impacted by these issues. To address this challenge, Ethiopia has implemented a cash and food safety net program over many years. However, there is limited information available regarding the program\'s factors and spatial distributions, with no recent national evidence from Ethiopia. Consequently, the objective of this study is to investigate the spatial clustering and determinants of the Productive Safety Net Program (PSNP) in Ethiopia.
    UNASSIGNED: This study utilized data from the Ethiopian Demographic and Health Survey. The sample included 8,570 weighted households. Given the hierarchical nature of the data, a multilevel logistic regression model was employed to identify factors influencing the outcome variable. Geographical clusters of individuals receiving assistance from the PSNP were examined using SaTScan software and the Bernoulli model, along with the Kulldorff methods. The nationwide distribution of the program beneficiaries was visualized using ArcGIS version 10.8. Variables were considered statistically significant if their p-value was <0.05.
    UNASSIGNED: The overall coverage of the PSNP was 13.54% [95% confidence interval (CI): 12.84-14.29] among households in Ethiopia. The study revealed that people from richer households adjusted odds ratio [AOR = 0.46 (95% CI: (0.33, 0.64))], those from the richest households [AOR = 0.26 (95% CI:(0.17,0.41))], and those with educated household heads [AOR = 0.45 (95% CI:(0.28, 0.71))] have a lower likelihood of utilizing the PSNP compared to their counterparts. Conversely, a unit increase in household heads\' age [AOR = 1.02 (95% CI:(1.01, 1.02))] and family size [AOR = 1.05 (95% CI:1.021.10)] showed a higher likelihood of joining the PSNP, respectively. Household heads who have joined community health insurance [AOR = 3.21 (95% CI:(2.58, 4.01))] had significantly higher odds of being included in the PSNP than their counterparts. Heads who belong to a community with a high poverty level [AOR = 2.68 (95% CI:(1.51, 4.79))] and community health insurance [AOR = 2.49 (95% CI:(1.51, 4.11))] showed more inclination to utilize the PSNP compared to their counterparts.
    UNASSIGNED: PSNP was judged to have a low implementation status based on the findings gathered regarding it. We found factors such as age, sex, region, wealth, education, family size, regions, and health insurance to be statistically significant. Therefore, encouraging women empowerment, community-based awareness creation, and coordination with regional states is advisable.
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  • 文章类型: Journal Article
    人类活动是黄河流域滑坡的触发因素(YRB,中国)。然而,滑坡的空间分布受人类活动影响的程度尚不清楚。我们根据夜间光照数据和土地覆盖数据构建了人类活动强度指数(HAII)。回归和优势分析用于比较HAII的影响,降水,距离河流,距离故障,地形起伏和坡度对滑坡空间密度(LSD)的影响。结果表明,在YRB中,HAII,作为优势影响因素,对LSD有显著的正向影响。此外,人类对自然干扰的区域差异加剧了LSD的空间变异。为了量化人类对自然的干扰强度,通过量化人工和自然景观的坡度分布之间的差异,构建了人性冲突指数(HNCI)。结果表明,在YRB的中段,人类正在发展更陡峭的山区,导致更密集的滑坡。该研究为YRB滑坡风险管理和土地利用规划提供了参考。
    Human activities are a triggering factor for landslides in the Yellow River Basin (YRB, China). However, the extent to which the spatial distribution of landslides is affected by human activities is unclear. We constructed a human activity intensity index (HAII) based on nighttime light data and land cover data. Regression and dominance analyses were used to compare the effects of the HAII, precipitation, distance to river, distance to fault, topographic relief and slope on the landslides spatial density (LSD). The results showed that in the YRB, the HAII, as a dominance influencing factor, had a significant positive influence on the LSD. Moreover, regional differences in the human disturbance of nature intensify the spatial variation of LSD. To quantify the intensity of human disturbance to nature, a human-nature conflict index (HNCI) is constructed by quantifying the difference between the slope distributions of artificial and natural landscapes. The results show that in the middle section of the YRB, humans are developing more steep mountainous areas, leading to more dense landslides. This study provides a reference for landslide risk management and land use planning in the YRB.
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  • 文章类型: Journal Article
    硫(S)是一种重要的生物元素,在植物中具有重要的调节和催化功能,并与N和P紧密耦合。然而,对叶片S的整体化学计量模式及其与叶片N和P的关系的研究较少。我们为全球6652个站点的2600种植物物种编制了31939条基于叶子的数据记录。所有植物物种都分为不同的系统发育分类群和生长形式。采用标准主轴分析来拟合双变量元素关系。使用系统发育线性混合效应模型和多元回归模型将生物元素的变化划分为系统发育和环境,然后估计环境变量的重要性。全局几何平均叶S,N和P浓度分别为1.44、15.70和1.27mgg-1,植物群体间差异显著。叶片S-N-P呈正相关,忽略植物群。LN-LS的缩放指数,LP-LS和LN-LP分别为0.64、0.76和0.79,对于所有物种来说,但不同的植物群体。系统发育和环境都调节了生物元素。可变性,而不是平均温度,控制生物元素。系统发育比环境更能解释所有三种生物元素的浓度,其中S是受系统发育分类群影响最大的一个。
    Sulfur (S) is an essential bioelement with vital roles in serving regulatory and catalytic functions and tightly coupled with N and P in plants. However, globally stoichiometric patterns of leaf S and its relationships to leaf N and P are less well studied. We compiled 31 939 records of leaf-based data for 2600 plant species across 6652 sites worldwide. All plant species were divided into different phylogenetic taxa and growth forms. Standard major axis analysis was employed to fit the bivariate element relationships. A phylogenetic linear mixed-effect model and a multiple-regression model were used to partition the variations of bioelements into phylogeny and environments, and then to estimate the importance of environmental variables. Global geometric mean leaf S, N and P concentrations were 1.44, 15.70 and 1.27 mg g-1, respectively, with significant differences among plant groups. Leaf S-N-P positively correlated with each other, ignoring plant groups. The scaling exponents of LN-LS, LP-LS and LN-LP were 0.64, 0.76 and 0.79, respectively, for all species, but differed among plant groups. Both phylogeny and environments regulated the bioelements. The variability, rather than mean temperature, controlled the bioelements. Phylogeny explained more for the concentrations of all the three bioelements than environments, of which S was the one most affected by phylogenetic taxa.
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  • 文章类型: Journal Article
    海鸥通常依靠人类产生的废物作为其主要食物来源,有助于抗生素抗性细菌及其抗性基因的传播,本地和全球。我们对这一过程的理解仍然不完整,特别是与周围土壤和水的潜在相互作用。我们研究了小黑背海鸥,Larusfuscus,作为检查粪便细菌群落空间变化的模型,抗生素抗性基因(ARGs),和移动遗传元件(MGEs)及其与周围水和土壤的关系。我们在一个连接网络中进行了抽样活动,该网络由跨功能单元(FU)移动的不同海鸥群组成,每一个都代表一个高度互连的栖息地的模块,用于栖息和喂养。FU在栖息地使用方面有所不同,一些海鸥使用更多污染的场地(特别是垃圾填埋场),而其他人则更喜欢更自然的环境(例如,湿地或海滩)。来自羊群的海鸥中的粪便细菌群落访问并在垃圾填埋场花费更多的时间表现出更高的丰富性和多样性。粪便微生物群与土壤中的细菌群落显示出高度的组成重叠。与垃圾填埋场(11%)相比,与湿地土壤(6%)相比,重叠更大。与周围水中的细菌群落相比要低得多(垃圾填埋场和湿地水中的细菌群落分别为2%和1%,分别)。FU之间ARG和MGE的相对丰度相似,仅在ARG和MGE的特定家族中观察到差异。当探索鸟类粪便中ARG和MGE相对于土壤和水隔室的粪便运输时,海鸥粪便富含被归类为高风险的ARGs。我们的结果揭示了野生鸟类种群中抗生素耐药性传播的复杂动态,提供对海鸥运动和进食行为之间相互作用的见解,生境特征,以及抗生素抗性决定因素在环境水库中的传播。
    Gulls commonly rely on human-generated waste as their primary food source, contributing to the spread of antibiotic-resistant bacteria and their resistance genes, both locally and globally. Our understanding of this process remains incomplete, particularly in relation to its potential interaction with surrounding soil and water. We studied the lesser black-backed gull, Larus fuscus, as a model to examine the spatial variation of faecal bacterial communities, antibiotic resistance genes (ARGs), and mobile genetic elements (MGEs) and its relationship with the surrounding water and soil. We conducted sampling campaigns within a connectivity network of different flocks of gulls moving across functional units (FUs), each of which represents a module of highly interconnected patches of habitats used for roosting and feeding. The FUs vary in habitat use, with some gulls using more polluted sites (notably landfills), while others prefer more natural environments (e.g., wetlands or beaches). Faecal bacterial communities in gulls from flocks that visit and spend more time in landfills exhibited higher richness and diversity. The faecal microbiota showed a high compositional overlap with bacterial communities in soil. The overlap was greater when compared to landfill (11%) than to wetland soils (6%), and much lower when compared to bacterial communities in surrounding water (2% and 1% for landfill and wetland water, respectively). The relative abundance of ARGs and MGEs were similar between FUs, with variations observed only for specific families of ARGs and MGEs. When exploring the faecal carriage of ARGs and MGEs in bird faeces relative to soil and water compartments, gull faeces were enriched in ARGs classified as High-Risk. Our results shed light on the complex dynamics of antibiotic resistance spread in wild bird populations, providing insights into the interactions among gull movement and feeding behavior, habitat characteristics, and the dissemination of antibiotic resistance determinants across environmental reservoirs.
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  • 文章类型: Journal Article
    这项研究探讨了出生地和居住地在英国成年期认知变化中的作用。我们利用英国生物库中的大样本量和认知领域的数量,使用多层次建模来估计出生地和居住地对成年认知的影响。我们发现,与美国的研究一致,在两个时间点的位置效应在所有测量的认知域中贡献了适度的变异(<3%的变异),这表明共享环境在解释未来阿尔茨海默病和相关痴呆方面相对缺乏贡献。此外,女性对成年后认知功能的地理贡献略大于男性。这项研究是首次探索出生地和居住地与不同认知领域的独立和联合关联的影响。
    This study explores the role that place of birth and place of residence have in variation in cognition in adulthood in the UK. We take advantage of both the large sample size and number of cognitive domains in the UK Biobank to estimate the effect of place of birth and place of residence on adulthood cognition using multilevel modeling. We find, consistent with studies in the US, that place effects at both time points contribute modest variation (<3% of the variation) across all measured cognitive domains, suggesting a relative lack of contribution of shared environments in explaining future Alzheimer\'s Disease and Related Dementias. Moreover, the geographical contribution to cognitive function in adulthood was slightly larger for females than for males. This study is among the first to explore the impact of both the independent and joint associations of place of birth and place of residence with different cognitive domains.
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